PubMed

Association of the FTO gene with obesity and the metabolic syndrome is independent of the IRS-2 gene in the female population of Southern France.

Attaoua R, Ait El Mkadem S, Lautier C, Kaouache S, Renard E, Brun JF, Fedou C, Gris JC, Bringer J, Grigorescu F.

Diabetes Metab. 2009 Oct 8. [Epub ahead of print]PMID: 19818665 [PubMed - as supplied by publisher]Related articles

[Glucose homeostasis, diabetes and neurodegenerative disorders]

Lautier C, Grigorescu F.

Med Sci (Paris). 2009 Apr;25(4):337-40. French. No abstract available. PMID: 19409181 [PubMed - indexed for MEDLINE]Related articles

FTO gene associates to metabolic syndrome in women with polycystic ovary syndrome.

Attaoua R, Ait El Mkadem S, Radian S, Fica S, Hanzu F, Albu A, Gheorghiu M, Coculescu M, Grigorescu F.

Biochem Biophys Res Commun. 2008 Aug 22;373(2):230-4. Epub 2008 Jun 20.PMID: 18572014 [PubMed - indexed for MEDLINE]Related articles

Follow-up study of two sisters with type A syndrome of severe insulin resistance gives a new insight into PCOS pathogenesis in relation to puberty and pregnancy outcome: a case report.

Vambergue A, Lautier C, Valat AS, Cortet-Rudelli C, Grigorescu F, Dewailly D.

Hum Reprod. 2006 May;21(5):1274-8. Epub 2006 Jan 12.PMID: 16410336 [PubMed - indexed for MEDLINE]Related articlesFree article

IGF-I receptor mutations resulting in intrauterine and postnatal growth retardation.

Abuzzahab MJ, Schneider A, Goddard A, Grigorescu F, Lautier C, Keller E, Kiess W, Klammt J, Kratzsch J, Osgood D, Pfäffle R, Raile K, Seidel B, Smith RJ, Chernausek SD; Intrauterine Growth Retardation (IUGR) Study Group.

N Engl J Med. 2003 Dec 4;349(23):2211-22.PMID: 14657428 [PubMed - indexed for MEDLINE]Related articlesFree article

Complex haplotypes of IRS2 gene are associated with severe obesity and reveal heterogeneity in the effect of Gly1057Asp mutation.

Lautier C, El Mkadem SA, Renard E, Brun JF, Gris JC, Bringer J, Grigorescu F.

Hum Genet. 2003 Jul;113(1):34-43. Epub 2003 Apr 10.PMID: 12687350 [PubMed - indexed for MEDLINE]Related articles

Genotype-phenotype relationships in Berardinelli-Seip congenital lipodystrophy.

Van Maldergem L, Magré J, Khallouf TE, Gedde-Dahl T Jr, Delépine M, Trygstad O, Seemanova E, Stephenson T, Albott CS, Bonnici F, Panz VR, Medina JL, Bogalho P, Huet F, Savasta S, Verloes A, Robert JJ, Loret H, De Kerdanet M, Tubiana-Rufi N, Mégarbané A, Maassen J, Polak M, Lacombe D, Kahn CR, Silveira EL, D'Abronzo FH, Grigorescu F, Lathrop M, Capeau J, O'Rahilly S.

J Med Genet. 2002 Oct;39(10):722-33. Erratum in: J Med Genet. 2003 Feb;40(2):150.. PMID: 12362029 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of allelic variants Gly972Arg of IRS-1 and Gly1057Asp of IRS-2 in moderate-to-severe insulin resistance of women with polycystic ovary syndrome.

El Mkadem SA, Lautier C, Macari F, Molinari N, Lefèbvre P, Renard E, Gris JC, Cros G, Daurès JP, Bringer J, White MF, Grigorescu F.

Diabetes. 2001 Sep;50(9):2164-8.PMID: 11522686 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of the gene altered in Berardinelli-Seip congenital lipodystrophy on chromosome 11q13.

Magré J, Delépine M, Khallouf E, Gedde-Dahl T Jr, Van Maldergem L, Sobel E, Papp J, Meier M, Mégarbané A, Bachy A, Verloes A, d'Abronzo FH, Seemanova E, Assan R, Baudic N, Bourut C, Czernichow P, Huet F, Grigorescu F, de Kerdanet M, Lacombe D, Labrune P, Lanza M, Loret H, Matsuda F, Navarro J, Nivelon-Chevalier A, Polak M, Robert JJ, Tric P, Tubiana-Rufi N, Vigouroux C, Weissenbach J, Savasta S, Maassen JA, Trygstad O, Bogalho P, Freitas P, Medina JL, Bonnicci F, Joffe BI, Loyson G, Panz VR, Raal FJ, O'Rahilly S, Stephenson T, Kahn CR, Lathrop M, Capeau J; BSCL Working Group.

Nat Genet. 2001 Aug;28(4):365-70.PMID: 11479539 [PubMed - indexed for MEDLINE]Related articles

[Insulin sensitivity and polycystic ovarian syndrome]

Bringer J, Raingeard I, Renard E, Grigorescu F, Lefebvre P.

Diabetes Metab. 2001 Apr;27(2 Pt 2):239-45. Review. French. PMID: 11452217 [PubMed - indexed for MEDLINE]Related articlesFree article

[Insulin resistance: from clinical diagnosis to molecular genetics. Implications in diabetes mellitus]

Jaffiol C, Rouard M, Macari F, Lautier C, Ait el Mkadem S, Méchaly I, Brun JF, Renard E, Cros G, Bringer J, Grigorescu F.

Bull Acad Natl Med. 1999;183(9):1761-75; discussion 1775-7. Review. French. PMID: 10987057 [PubMed - indexed for MEDLINE]Related articles

Studies of the variability of the genes encoding the insulin-like growth factor I receptor and its ligand in relation to type 2 diabetes mellitus.

Rasmussen SK, Lautier C, Hansen L, Echwald SM, Hansen T, Ekstrøm CT, Urhammer SA, Borch-Johnsen K, Grigorescu F, Smith RJ, Pedersen O.

J Clin Endocrinol Metab. 2000 Apr;85(4):1606-10.PMID: 10770205 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification by RT-PCR and immunolocalization of arginine vasopressin in rat pancreas.

Méchaly I, Macari F, Laliberté MF, Lautier C, Serrano JJ, Cros G, Grigorescu F.

Diabetes Metab. 1999 Dec;25(6):498-501.PMID: 10633874 [PubMed - indexed for MEDLINE]Related articlesFree article

Congenital insulin resistance associated with a conformational alteration in a conserved beta-sheet in the insulin receptor L1 domain.

Rouard M, Bass J, Grigorescu F, Garrett TP, Ward CW, Lipkind G, Jaffiole C, Steiner DF, Bell GI.

J Biol Chem. 1999 Jun 25;274(26):18487-91.PMID: 10373457 [PubMed - indexed for MEDLINE]Related articlesFree article

Refinement of genetic localization of the Alström syndrome on chromosome 2p12-13 by linkage analysis in a North African family.

Macari F, Lautier C, Girardet A, Dadoun F, Darmon P, Dutour A, Renard E, Bouvagnet P, Claustres M, Oliver C, Grigorescu F.

Hum Genet. 1998 Dec;103(6):658-61.PMID: 9921899 [PubMed - indexed for MEDLINE]Related articles

Identification and sequence analysis of arginine vasopressin mRNA in normal and Brattleboro rat aortic tissue.

Méchaly I, Macari F, Lautier C, Serrano JJ, Cros G, Grigorescu F.

Eur J Endocrinol. 1998 Jul;139(1):123-6.PMID: 9703389 [PubMed - indexed for MEDLINE]Related articlesFree article

Decrease in insulin and insulin-like growth factor I (IGF-I) binding to erythrocytes from patients with cystic fibrosis.

Dooghe C, Grizard G, Labbe A, Grigorescu F, Dardevet D, Grizard J.

Diabetes Metab. 1997 Dec;23(6):511-8.PMID: 9496557 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of two novel insulin receptor mutations, Asp59Gly and Leu62Pro, in type A syndrome of extreme insulin resistance.

Rouard M, Macari F, Bouix O, Lautier C, Brun JF, Lefebvre P, Renard E, Bringer J, Jaffiol C, Grigorescu F.

Biochem Biophys Res Commun. 1997 May 29;234(3):764-8.PMID: 9175790 [PubMed - indexed for MEDLINE]Related articles

Characterization of vanadyl sulfate effect on vascular contraction: roles of calcium and tyrosine phosphorylation.

Cadène A, Grigorescu F, Serrano JJ, Cros G.

J Pharmacol Exp Ther. 1997 Apr;281(1):491-8.PMID: 9103536 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-dependent phosphatidylinositol 3'-kinase activity co-precipitates with insulin receptor in human circulating mononuclear cells.

Renard E, Grigorescu F, Lavabre C, Kahn CR.

Biochem Biophys Res Commun. 1995 Apr 6;209(1):234-41.PMID: 7726840 [PubMed - indexed for MEDLINE]Related articles

Involvement of phosphoinositide 3-kinase in insulin- or IGF-1-induced membrane ruffling.

Kotani K, Yonezawa K, Hara K, Ueda H, Kitamura Y, Sakaue H, Ando A, Chavanieu A, Calas B, Grigorescu F, et al.

EMBO J. 1994 May 15;13(10):2313-21.PMID: 8194523 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevalence of mutations in the insulin receptor gene in subjects with features of the type A syndrome of insulin resistance.

Moller DE, Cohen O, Yamaguchi Y, Assiz R, Grigorescu F, Eberle A, Morrow LA, Moses AC, Flier JS.

Diabetes. 1994 Feb;43(2):247-55.PMID: 8288049 [PubMed - indexed for MEDLINE]Related articles

Insulin and IGF-1 signaling in oocyte maturation.

Grigorescu F, Baccara MT, Rouard M, Renard E.

Horm Res. 1994;42(1-2):55-61. Review.PMID: 7959635 [PubMed - indexed for MEDLINE]Related articles

Substrate specificity of the insulin receptor tyrosine kinase domain.

Keane NE, Levine BA, Quirk P, Calas B, Chavanieu A, Grigorescu F, Ellis L.

Biochem Soc Trans. 1993 Aug;21 ( Pt 3)(3):266S. No abstract available. PMID: 8224418 [PubMed - indexed for MEDLINE]Related articles

Insulin-mediated pseudoacromegaly: clinical and biochemical characterization of a syndrome of selective insulin resistance.

Flier JS, Moller DE, Moses AC, O'Rahilly S, Chaiken RL, Grigorescu F, Elahi D, Kahn BB, Weinreb JE, Eastman R.

J Clin Endocrinol Metab. 1993 Jun;76(6):1533-41.PMID: 8388881 [PubMed - indexed for MEDLINE]Related articles

Body composition and regional fat distribution in polycystic ovarian syndrome. Relationship to hormonal and metabolic profiles.

Bringer J, Lefebvre P, Boulet F, Grigorescu F, Renard E, Hedon B, Orsetti A, Jaffiol C.

Ann N Y Acad Sci. 1993 May 28;687:115-23. No abstract available. PMID: 8323166 [PubMed - indexed for MEDLINE]Related articles

Resin immobilized synthetic peptides used to characterize phosphorylation and antigenic properties of insulin receptor autophosphorylation domains.

Chavanieu A, Calas B, Grigorescu F.

Int J Pept Protein Res. 1993 Mar;41(3):212-22.PMID: 7681813 [PubMed - indexed for MEDLINE]Related articles

Kinase inhibition by a phosphorylated peptide corresponding to the major insulin receptor autophosphorylation domain.

Chavanieu A, Calas B, Vaglio P, Grigorescu F.

Eur J Biochem. 1992 Sep 1;208(2):367-73.PMID: 1381676 [PubMed - indexed for MEDLINE]Related articlesFree article

Cellular mechanism of metformin action.

Grigorescu F, Laurent A, Chavanieu A, Capony JP.

Diabete Metab. 1991 May;17(1 Pt 2):146-9. Review.PMID: 1936468 [PubMed - indexed for MEDLINE]Related articles

Tyrosine-kinase defect of the insulin receptor in cultured fibroblasts from patients with lipoatropic diabetes.

Magré J, Grigorescu F, Reynet C, Caron M, Capony JP, White MF, Picard J, Mirouze J, Capeau J.

J Clin Endocrinol Metab. 1989 Jul;69(1):142-50.PMID: 2543688 [PubMed - indexed for MEDLINE]Related articles

Defects in insulin binding and autophosphorylation of erythrocyte insulin receptors in patients with syndromes of severe insulin resistance and their parents.

Grigorescu F, Herzberg V, King G, Meistas M, Elders J, Frazer T, Kahn CR.

J Clin Endocrinol Metab. 1987 Mar;64(3):549-56.PMID: 3029156 [PubMed - indexed for MEDLINE]Related articles

Effects of heparin on insulin binding and biological activity.

Kriauciunas KM, Grigorescu F, Kahn CR.

Diabetes. 1987 Feb;36(2):163-8.PMID: 3542643 [PubMed - indexed for MEDLINE]Related articles

Carbohydrate metabolism in women who used oral contraceptives containing levonorgestrel or desogestrel: a 6-month prospective study.

Luyckx AS, Gaspard UJ, Romus MA, Grigorescu F, De Meyts P, Lefèbvre PJ.

Fertil Steril. 1986 May;45(5):635-42.PMID: 2938985 [PubMed - indexed for MEDLINE]Related articles

The human erythrocyte insulin-like growth factor I receptor: characterization and demonstration of ligand-stimulated autophosphorylation.

Catanese VM, Grigorescu F, King GL, Kahn CR.

J Clin Endocrinol Metab. 1986 Apr;62(4):692-9.PMID: 3005355 [PubMed - indexed for MEDLINE]Related articles

Characterization of binding and phosphorylation defects of erythrocyte insulin receptors in the type A syndrome of insulin resistance.

Grigorescu F, Flier JS, Kahn CR.

Diabetes. 1986 Feb;35(2):127-38.PMID: 3510919 [PubMed - indexed for MEDLINE]Related articles

Distribution and characterization of insulin and insulin-like growth factor I receptors in normal human ovary.

Poretsky L, Grigorescu F, Seibel M, Moses AC, Flier JS.

J Clin Endocrinol Metab. 1985 Oct;61(4):728-34.PMID: 2993346 [PubMed - indexed for MEDLINE]Related articles

Characterization of insulin receptor carbohydrate by comparison of chemical and enzymatic deglycosylation.

Herzberg VL, Grigorescu F, Edge AS, Spiro RG, Kahn CR.

Biochem Biophys Res Commun. 1985 Jun 28;129(3):789-96.PMID: 2990467 [PubMed - indexed for MEDLINE]Related articles

Defect in insulin receptor phosphorylation in erythrocytes and fibroblasts associated with severe insulin resistance.

Grigorescu F, Flier JS, Kahn CR.

J Biol Chem. 1984 Dec 25;259(24):15003-6.PMID: 6392291 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin binding and insulin-dependent phosphorylation of the insulin receptor solubilized from human erythrocytes.

Grigorescu F, White MF, Kahn CR.

J Biol Chem. 1983 Nov 25;258(22):13708-16.PMID: 6358209 [PubMed - indexed for MEDLINE]Related articlesFree article

[Clinical usefulness of the determination of erythrocyte insulin receptors]

Grigorescu F, Lambert B, De Meyts P.

Journ Annu Diabetol Hotel Dieu. 1982:31-4. French. No abstract available. PMID: 7098254 [PubMed - indexed for MEDLINE]Related articles

High level of human growth hormone (HGH) in cerebrospinal fluid patients with pituitary tumors.

Coculescu M, Simionescu L, Constantinovici A, Login SS, Simionescu N, Dimitriu V, Oprescu M, Grigorescu F.

Endocrinologie. 1979 Jul-Sep;17(3):205-11.PMID: 504962 [PubMed - indexed for MEDLINE]Related articles

Administration of arginine-vasotocin (AVT) to human subjects.

Coculescu M, Simionescu L, Cristoveanu A, Serbänescu A, Matulevicius V, Grigorescu F, Temeli E.

Prog Brain Res. 1979;52:535-7. No abstract available. PMID: 121475 [PubMed - indexed for MEDLINE]Related articles

Blood-cerebrospinal fluid barrier for human growth hormone.

Grigorescu F, Coculescu M, Dimitriu V, Iager AC.

Neurol Psychiatr (Bucur). 1978 Jan-Mar;16(1):33-6. No abstract available. PMID: 635415 [PubMed - indexed for MEDLINE]Related articles

[Incomplete chronic duodenal stenosis caused by compression by the aorta and mesenteric artery]

Pretorian R, Grigorescu A, Vosnesenschi M, Grigorescu F, Guluţà V, Jager A.

Rev Chir Oncol Radiol O R L Oftalmol Stomatol Chir. 1976 May-Jun;25(3):193-8. Romanian. PMID: 134404 [PubMed - indexed for MEDLINE]Related articles