PubMed

The strength of T cell receptor signal controls the polarization of cytotoxic machinery to the immunological synapse.

Jenkins MR, Tsun A, Stinchcombe JC, Griffiths GM.

Immunity. 2009 Oct 16;31(4):621-31.PMID: 19833087 [PubMed - indexed for MEDLINE]Related articles

FRAGMATIC: a randomised phase III clinical trial investigating the effect of fragmin added to standard therapy in patients with lung cancer.

Griffiths GO, Burns S, Noble SI, Macbeth FR, Cohen D, Maughan TS.

BMC Cancer. 2009 Oct 6;9:355.PMID: 19807917 [PubMed - in process]Related articlesFree article

Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11.

zur Stadt U, Rohr J, Seifert W, Koch F, Grieve S, Pagel J, Strauss J, Kasper B, Nürnberg G, Becker C, Maul-Pavicic A, Beutel K, Janka G, Griffiths G, Ehl S, Hennies HC.

Am J Hum Genet. 2009 Oct;85(4):482-92.PMID: 19804848 [PubMed - indexed for MEDLINE]Related articles

Inflammatory gene expression in response to sub-lethal ricin exposure in Balb/c mice.

David J, Wilkinson LJ, Griffiths GD.

Toxicology. 2009 Oct 1;264(1-2):119-30. Epub 2009 Aug 12.PMID: 19682533 [PubMed - indexed for MEDLINE]Related articles

Two patients with Hermansky Pudlak Syndrome Type 2 and novel mutations in AP3B1.

Wenham M, Grieve S, Cummins M, Jones ML, Booth S, Kilner R, Ancliff PJ, Griffiths GM, Mumford AD.

Haematologica. 2009 Aug 13. [Epub ahead of print]PMID: 19679886 [PubMed - as supplied by publisher]Related articlesFree article

Broad recognition of ricin toxins prepared from a range of Ricinus cultivars using immunochromatographic tests.

Thullier P, Griffiths G.

Clin Toxicol (Phila). 2009 Aug;47(7):643-50.PMID: 19656008 [PubMed - indexed for MEDLINE]Related articles

Transient assembly of F-actin by phagosomes delays phagosome fusion with lysosomes in cargo-overloaded macrophages.

Liebl D, Griffiths G.

J Cell Sci. 2009 Aug 15;122(Pt 16):2935-45. Epub 2009 Jul 28.PMID: 19638408 [PubMed - indexed for MEDLINE]Related articles

Help is just a text away: The use of short message service texting to provide an additional means of support for health care students during practice placements.

Young P, Moore E, Griffiths G, Raine R, Stewart R, Cownie M, Frutos-Perez M.

Nurse Educ Today. 2009 Jul 23. [Epub ahead of print]PMID: 19632011 [PubMed - as supplied by publisher]Related articles

Membrane rupture generates single open membrane sheets during vaccinia virus assembly.

Chlanda P, Carbajal MA, Cyrklaff M, Griffiths G, Krijnse-Locker J.

Cell Host Microbe. 2009 Jul 23;6(1):81-90.PMID: 19616767 [PubMed - indexed for MEDLINE]Related articles

TNF-alpha-induced up-regulation of pro-inflammatory cytokines is reduced by phosphatidylcholine in intestinal epithelial cells.

Treede I, Braun A, Jeliaskova P, Giese T, Füllekrug J, Griffiths G, Stremmel W, Ehehalt R.

BMC Gastroenterol. 2009 Jul 13;9:53.PMID: 19594939 [PubMed - indexed for MEDLINE]Related articlesFree article

Melt brushes of diblock copolymer.

Matsen MW, Griffiths GH.

Eur Phys J E Soft Matter. 2009 Jun;29(2):219-27. Epub 2009 Jun 24.PMID: 19551414 [PubMed]Related articles

Physiologic upper limit of pore size in the blood-tumor barrier of malignant solid tumors.

Sarin H, Kanevsky AS, Wu H, Sousa AA, Wilson CM, Aronova MA, Griffiths GL, Leapman RD, Vo HQ.

J Transl Med. 2009 Jun 23;7:51.PMID: 19549317 [PubMed - indexed for MEDLINE]Related articlesFree article

Facilitating comfort for hospitalized patients using non-pharmacological measures: preliminary development of clinical practice guidelines.

Williams AM, Davies A, Griffiths G.

Int J Nurs Pract. 2009 Jun;15(3):145-55. Review.PMID: 19531072 [PubMed - indexed for MEDLINE]Related articles

Synthesis and characterization of a new fluorogenic substrate for alpha-galactosidase.

Shi ZD, Motabar O, Goldin E, Liu K, Southall N, Sidransky E, Austin CP, Griffiths GL, Zheng W.

Anal Bioanal Chem. 2009 Aug;394(7):1903-9. Epub 2009 Jun 13.PMID: 19521690 [PubMed - indexed for MEDLINE]Related articlesFree article

Radioactivity-synchronized fluorescence enhancement using a radionuclide fluorescence-quenched dye.

Berezin MY, Guo K, Teng B, Edwards WB, Anderson CJ, Vasalatiy O, Gandjbakhche A, Griffiths GL, Achilefu S.

J Am Chem Soc. 2009 Jul 8;131(26):9198-200.PMID: 19514722 [PubMed - indexed for MEDLINE]Related articles

Determining molecular mass distributions and compositions of functionalized dendrimer nanoparticles.

Sousa AA, Aronova MA, Wu H, Sarin H, Griffiths GL, Leapman RD.

Nanomed. 2009 Jun;4(4):391-9.PMID: 19505242 [PubMed - indexed for MEDLINE]Related articles

Porins facilitate nitric oxide-mediated killing of mycobacteria.

Fabrino DL, Bleck CK, Anes E, Hasilik A, Melo RC, Niederweis M, Griffiths G, Gutierrez MG.

Microbes Infect. 2009 Sep;11(10-11):868-75. Epub 2009 May 19.PMID: 19460455 [PubMed - indexed for MEDLINE]Related articles

A new resorufin-based alpha-glucosidase assay for high-throughput screening.

Motabar O, Shi ZD, Goldin E, Liu K, Southall N, Sidransky E, Austin CP, Griffiths GL, Zheng W.

Anal Biochem. 2009 Jul 1;390(1):79-84. Epub 2009 Apr 14.PMID: 19371716 [PubMed - indexed for MEDLINE]Related articles

Clusterin facilitates exchange of glycosyl phosphatidylinositol-linked SPAM1 between reproductive luminal fluids and mouse and human sperm membranes.

Griffiths GS, Galileo DS, Aravindan RG, Martin-DeLeon PA.

Biol Reprod. 2009 Sep;81(3):562-70. Epub 2009 Apr 8.PMID: 19357365 [PubMed - in process]Related articles

A phase II trial of continuous 5-fluorouracil in recurrent or metastatic transitional cell carcinoma of the urinary tract.

Highley MS, Griffiths GO, Uscinska BM, Huddart RA, Barber JB, Parmar MK, Harper PG; NCRI Bladder Cancer Clinical Studies Group.

Clin Oncol (R Coll Radiol). 2009 Jun;21(5):394-400. Epub 2009 Mar 9.PMID: 19269798 [PubMed - indexed for MEDLINE]Related articles

Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial.

Sebag-Montefiore D, Stephens RJ, Steele R, Monson J, Grieve R, Khanna S, Quirke P, Couture J, de Metz C, Myint AS, Bessell E, Griffiths G, Thompson LC, Parmar M.

Lancet. 2009 Mar 7;373(9666):811-20.PMID: 19269519 [PubMed - indexed for MEDLINE]Related articlesFree article

Researching breathlessness in palliative care: consensus statement of the National Cancer Research Institute Palliative Care Breathlessness Subgroup.

Dorman S, Jolley C, Abernethy A, Currow D, Johnson M, Farquhar M, Griffiths G, Peel T, Moosavi S, Byrne A, Wilcock A, Alloway L, Bausewein C, Higginson I, Booth S.

Palliat Med. 2009 Apr;23(3):213-27. Epub 2009 Feb 27.PMID: 19251835 [PubMed - in process]Related articles

Lipids regulate P2X7-receptor-dependent actin assembly by phagosomes via ADP translocation and ATP synthesis in the phagosome lumen.

Kuehnel MP, Rybin V, Anand PK, Anes E, Griffiths G.

J Cell Sci. 2009 Feb 15;122(Pt 4):499-504. Epub 2009 Jan 27.PMID: 19174471 [PubMed - indexed for MEDLINE]Related articlesFree article

Sphingosine-1-phosphate receptors stimulate macrophage plasma-membrane actin assembly via ADP release, ATP synthesis and P2X7R activation.

Kuehnel MP, Reiss M, Anand PK, Treede I, Holzer D, Hoffmann E, Klapperstueck M, Steinberg TH, Markwardt F, Griffiths G.

J Cell Sci. 2009 Feb 15;122(Pt 4):505-12. Epub 2009 Jan 27.PMID: 19174470 [PubMed - indexed for MEDLINE]Related articlesFree article

Candida albicans actively modulates intracellular membrane trafficking in mouse macrophage phagosomes.

Fernández-Arenas E, Bleck CK, Nombela C, Gil C, Griffiths G, Diez-Orejas R.

Cell Microbiol. 2009 Apr;11(4):560-89. Epub 2008 Dec 24.PMID: 19134116 [PubMed - indexed for MEDLINE]Related articles

Effective transvascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells.

Sarin H, Kanevsky AS, Wu H, Brimacombe KR, Fung SH, Sousa AA, Auh S, Wilson CM, Sharma K, Aronova MA, Leapman RD, Griffiths GL, Hall MD.

J Transl Med. 2008 Dec 18;6:80.PMID: 19094226 [PubMed - indexed for MEDLINE]Related articlesFree article

Association between periodontitis and common variants in the promoter of the interleukin-6 gene.

Nibali L, D'Aiuto F, Donos N, Griffiths GS, Parkar M, Tonetti MS, Humphries SE, Brett PM.

Cytokine. 2009 Jan;45(1):50-4. Epub 2008 Dec 11.PMID: 19084430 [PubMed - indexed for MEDLINE]Related articles

Modelling phagosomal lipid networks that regulate actin assembly.

Kühnel M, Mayorga LS, Dandekar T, Thakar J, Schwarz R, Anes E, Griffiths G, Reich J.

BMC Syst Biol. 2008 Dec 5;2:107.PMID: 19061496 [PubMed - indexed for MEDLINE]Related articlesFree article

Balloon angioplasty as the primary treatment for failing infra-inguinal vein grafts.

Mofidi R, Flett M, Nagy J, Ross R, Griffiths GD, Chakraverty S, Stonebridge PA.

Eur J Vasc Endovasc Surg. 2009 Feb;37(2):198-205. Epub 2008 Nov 28.PMID: 19046905 [PubMed - indexed for MEDLINE]Related articles

Role of lipids in killing mycobacteria by macrophages: evidence for NF-kappaB-dependent and -independent killing induced by different lipids.

Gutierrez MG, Gonzalez AP, Anes E, Griffiths G.

Cell Microbiol. 2009 Mar;11(3):406-20. Epub 2008 Nov 7.PMID: 19016780 [PubMed - indexed for MEDLINE]Related articles

Outcome from abdominal aortic aneurysms in Scotland, 1991-2006.

Mofidi R, Suttie SA, Howd A, Dawson AR, Griffiths GD, Stonebridge PA.

Br J Surg. 2008 Dec;95(12):1475-9.PMID: 18991274 [PubMed - indexed for MEDLINE]Related articles

Application of high-content analysis to the study of post-translational modifications of the cytoskeleton.

Drake PJ, Griffiths GJ, Shaw L, Benson RP, Corfe BM.

J Proteome Res. 2009 Jan;8(1):28-34.PMID: 18983182 [PubMed - indexed for MEDLINE]Related articles

Too old to exercise? Unusual muscular uptake on 99mTc methylene diphosphonate bone scintigraphy.

Griffiths G, Rees J.

Br J Hosp Med (Lond). 2008 Oct;69(10):592. No abstract available. PMID: 18949952 [PubMed - indexed for MEDLINE]Related articles

Effects of omega-3 and -6 fatty acids on Mycobacterium tuberculosis in macrophages and in mice.

Jordao L, Lengeling A, Bordat Y, Boudou F, Gicquel B, Neyrolles O, Becker PD, Guzman CA, Griffiths G, Anes E.

Microbes Infect. 2008 Oct;10(12-13):1379-86. Epub 2008 Aug 14.PMID: 18771745 [PubMed - indexed for MEDLINE]Related articles

A familial analysis of aggressive periodontitis - clinical and genetic findings.

Nibali L, Donos N, Brett PM, Parkar M, Ellinas T, Llorente M, Griffiths GS.

J Periodontal Res. 2008 Dec;43(6):627-34. Epub 2008 Aug 22.PMID: 18752567 [PubMed - indexed for MEDLINE]Related articles

Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum.

Axe EL, Walker SA, Manifava M, Chandra P, Roderick HL, Habermann A, Griffiths G, Ktistakis NT.

J Cell Biol. 2008 Aug 25;182(4):685-701.PMID: 18725538 [PubMed - indexed for MEDLINE]Related articlesFree article

Mitochondrial NADH fluorescence is enhanced by complex I binding.

Blinova K, Levine RL, Boja ES, Griffiths GL, Shi ZD, Ruddy B, Balaban RS.

Biochemistry. 2008 Sep 9;47(36):9636-45. Epub 2008 Aug 15.PMID: 18702505 [PubMed - indexed for MEDLINE]Related articles

Cetuximab therapy in first-line metastatic colorectal cancer and intermittent palliative chemotherapy: review of the COIN trial.

Adams R, Meade A, Wasan H, Griffiths G, Maughan T.

Expert Rev Anticancer Ther. 2008 Aug;8(8):1237-45. Review.PMID: 18699762 [PubMed - indexed for MEDLINE]Related articles

NF-kappa B activation controls phagolysosome fusion-mediated killing of mycobacteria by macrophages.

Gutierrez MG, Mishra BB, Jordao L, Elliott E, Anes E, Griffiths G.

J Immunol. 2008 Aug 15;181(4):2651-63.PMID: 18684956 [PubMed - indexed for MEDLINE]Related articlesFree article

Use of a Javidtrade mark shunt in the management of axillary artery injury as a complication of fracture of the surgical neck of the humerus: a case report.

Suttie SA, Mofidi R, Howd A, Griffiths GD.

J Med Case Reports. 2008 Aug 5;2:259.PMID: 18681953 [PubMed - in process]Related articlesFree article

The value of vein graft surveillance in bypasses performed with small-diameter vein grafts.

Mofidi R, Pandanaboyana S, Flett MM, Nagy J, Griffiths GD, Stonebridge PA; East of Scotland Vascular Network.

Ann Vasc Surg. 2009 Jan-Feb;23(1):17-23. Epub 2008 Jul 10.PMID: 18619778 [PubMed - indexed for MEDLINE]Related articles

Preparation of cells and tissues for immuno EM.

Webster P, Schwarz H, Griffiths G.

Methods Cell Biol. 2008;88:45-58. Review.PMID: 18617027 [PubMed - indexed for MEDLINE]Related articles

Direct visualization of the outer membrane of mycobacteria and corynebacteria in their native state.

Zuber B, Chami M, Houssin C, Dubochet J, Griffiths G, Daffé M.

J Bacteriol. 2008 Aug;190(16):5672-80. Epub 2008 Jun 20.PMID: 18567661 [PubMed - indexed for MEDLINE]Related articlesFree article

Development of a model of hookworm infection exhibiting salient characteristics of human infection.

Griffiths GD, Brown AP, Hooi DS, Pearce PC, Hornby RJ, Scott L, Pritchard DI.

Am J Trop Med Hyg. 2008 Jun;78(6):936-45.PMID: 18541773 [PubMed - indexed for MEDLINE]Related articlesFree article

Synthesis and pharmacological characterization of [(125)I]MRS1898, a high-affinity, selective radioligand for the rat A(3) adenosine receptor.

Gao ZG, Teng B, Wu H, Joshi BV, Griffiths GL, Jacobson KA.

Purinergic Signal. 2009 Mar;5(1):31-7. Epub 2008 Jun 5.PMID: 18528782 [PubMed - in process]Related articlesFree article

Mutations affecting mRNA splicing are the most common molecular defect in patients with familial hemophagocytic lymphohistiocytosis type 3.

Santoro A, Cannella S, Trizzino A, Bruno G, De Fusco C, Notarangelo LD, Pende D, Griffiths GM, Aricò M.

Haematologica. 2008 Jul;93(7):1086-90. Epub 2008 May 19.PMID: 18492689 [PubMed - indexed for MEDLINE]Related articlesFree article

The morpho-functional organization of secretory traffic. Here today, where tomorrow?

Luini A, Mironov AA, De Matteis MA, Griffiths G.

Med Secoli. 2007;19(1):29-54. Review.PMID: 18447166 [PubMed - indexed for MEDLINE]Related articles

Vitamin D receptor polymorphism (-1056 Taq-I) interacts with smoking for the presence and progression of periodontitis.

Nibali L, Parkar M, D'Aiuto F, Suvan JE, Brett PM, Griffiths GS, Rosin M, Schwahn C, Tonetti MS.

J Clin Periodontol. 2008 Jul;35(7):561-7. Epub 2008 Apr 10.PMID: 18410395 [PubMed - indexed for MEDLINE]Related articles

Investigating the role of murine epididymosomes and uterosomes in GPI-linked protein transfer to sperm using SPAM1 as a model.

Griffiths GS, Galileo DS, Reese K, Martin-Deleon PA.

Mol Reprod Dev. 2008 Nov;75(11):1627-36.PMID: 18384048 [PubMed - indexed for MEDLINE]Related articles

Murine SPAM1 is secreted by the estrous uterus and oviduct in a form that can bind to sperm during capacitation: acquisition enhances hyaluronic acid-binding ability and cumulus dispersal efficiency.

Griffiths GS, Miller KA, Galileo DS, Martin-DeLeon PA.

Reproduction. 2008 Mar;135(3):293-301.PMID: 18299422 [PubMed - indexed for MEDLINE]Related articlesFree article