PubMed

Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans.

Stanhope KL, Schwarz JM, Keim NL, Griffen SC, Bremer AA, Graham JL, Hatcher B, Cox CL, Dyachenko A, Zhang W, McGahan JP, Seibert A, Krauss RM, Chiu S, Schaefer EJ, Ai M, Otokozawa S, Nakajima K, Nakano T, Beysen C, Hellerstein MK, Berglund L, Havel PJ.

J Clin Invest. 2009 May;119(5):1322-34. doi: 10.1172/JCI37385. Epub 2009 Apr 20.PMID: 19381015 [PubMed - indexed for MEDLINE]Related articlesFree article

Development and characterization of a novel rat model of type 2 diabetes mellitus: the UC Davis type 2 diabetes mellitus UCD-T2DM rat.

Cummings BP, Digitale EK, Stanhope KL, Graham JL, Baskin DG, Reed BJ, Sweet IR, Griffen SC, Havel PJ.

Am J Physiol Regul Integr Comp Physiol. 2008 Dec;295(6):R1782-93. Epub 2008 Oct 1.PMID: 18832086 [PubMed - indexed for MEDLINE]Related articles

Twenty-four-hour endocrine and metabolic profiles following consumption of high-fructose corn syrup-, sucrose-, fructose-, and glucose-sweetened beverages with meals.

Stanhope KL, Griffen SC, Bair BR, Swarbrick MM, Keim NL, Havel PJ.

Am J Clin Nutr. 2008 May;87(5):1194-203.PMID: 18469239 [PubMed - indexed for MEDLINE]Related articlesFree article

Consumption of fructose-sweetened beverages for 10 weeks increases postprandial triacylglycerol and apolipoprotein-B concentrations in overweight and obese women.

Swarbrick MM, Stanhope KL, Elliott SS, Graham JL, Krauss RM, Christiansen MP, Griffen SC, Keim NL, Havel PJ.

Br J Nutr. 2008 Nov;100(5):947-52.PMID: 18384705 [PubMed - indexed for MEDLINE]Related articles

Increased toll-like receptor (TLR) 2 and TLR4 expression in monocytes from patients with type 1 diabetes: further evidence of a proinflammatory state.

Devaraj S, Dasu MR, Rockwood J, Winter W, Griffen SC, Jialal I.

J Clin Endocrinol Metab. 2008 Feb;93(2):578-83. Epub 2007 Nov 20.PMID: 18029454 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence of increased inflammation and microcirculatory abnormalities in patients with type 1 diabetes and their role in microvascular complications.

Devaraj S, Cheung AT, Jialal I, Griffen SC, Nguyen D, Glaser N, Aoki T.

Diabetes. 2007 Nov;56(11):2790-6. Epub 2007 Aug 8.PMID: 17686944 [PubMed - indexed for MEDLINE]Related articlesFree article

Concomitant reduction of low-density lipoprotein-cholesterol and biomarkers of inflammation with low-dose simvastatin therapy in patients with type 1 diabetes.

Jialal I, Miguelino E, Griffen SC, Devaraj S.

J Clin Endocrinol Metab. 2007 Aug;92(8):3136-40. Epub 2007 May 22.PMID: 17519305 [PubMed - indexed for MEDLINE]Related articlesFree article

Administration of Lispro insulin with meals improves glycemic control, increases circulating leptin, and suppresses ghrelin, compared with regular/NPH insulin in female patients with type 1 diabetes.

Griffen SC, Oostema K, Stanhope KL, Graham J, Styne DM, Glaser N, Cummings DE, Connors MH, Havel PJ.

J Clin Endocrinol Metab. 2006 Feb;91(2):485-91. Epub 2005 Nov 29.PMID: 16317063 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: application of pre-mRNA analysis and chromatin immunoprecipitation to assess formation of functional transcriptional complexes.

Iype T, Francis J, Garmey JC, Schisler JC, Nesher R, Weir GC, Becker TC, Newgard CB, Griffen SC, Mirmira RG.

J Biol Chem. 2005 Apr 29;280(17):16798-807. Epub 2005 Mar 2.PMID: 15743769 [PubMed - indexed for MEDLINE]Related articlesFree article

MAP kinases and their roles in pancreatic beta-cells.

Khoo S, Gibson TB, Arnette D, Lawrence M, January B, McGlynn K, Vanderbilt CA, Griffen SC, German MS, Cobb MH.

Cell Biochem Biophys. 2004;40(3 Suppl):191-200. Review.PMID: 15289654 [PubMed - indexed for MEDLINE]Related articles

Neurogenin3 and hepatic nuclear factor 1 cooperate in activating pancreatic expression of Pax4.

Smith SB, Gasa R, Watada H, Wang J, Griffen SC, German MS.

J Biol Chem. 2003 Oct 3;278(40):38254-9. Epub 2003 Jul 1.PMID: 12837760 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of insulin gene transcription by ERK1 and ERK2 in pancreatic beta cells.

Khoo S, Griffen SC, Xia Y, Baer RJ, German MS, Cobb MH.

J Biol Chem. 2003 Aug 29;278(35):32969-77. Epub 2003 Jun 16.PMID: 12810726 [PubMed - indexed for MEDLINE]Related articlesFree article

A genetic defect in beta-cell gene expression segregates independently from the fa locus in the ZDF rat.

Griffen SC, Wang J, German MS.

Diabetes. 2001 Jan;50(1):63-8.PMID: 11147796 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel glucose-responsive element in the human insulin gene functions uniquely in primary cultured islets.

Sander M, Griffen SC, Huang J, German MS.

Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):11572-7.PMID: 9751707 [PubMed - indexed for MEDLINE]Related articlesFree article

Vasopressin response to haemorrhage in rats: effect of hypoxia and water restriction.

Raff H, Rossing MH, Doepker SK, Griffen SC, Jankowski BM.

Clin Exp Pharmacol Physiol. 1991 Oct;18(10):725-9.PMID: 1764817 [PubMed - indexed for MEDLINE]Related articles

Vasopressin responses to hypoxia in conscious rats: interaction with water restriction.

Griffen SC, Raff H.

J Endocrinol. 1990 Apr;125(1):61-6.PMID: 2338532 [PubMed - indexed for MEDLINE]Related articles

Insulin exerts metabolic and growth-promoting effects by a direct action on the liver in vivo: clarification of the functional significance of the portal vascular link between the beta cells of the pancreatic islets and the liver.

Griffen SC, Russell SM, Katz LS, Nicoll CS.

Proc Natl Acad Sci U S A. 1987 Oct;84(20):7300-4.PMID: 3313390 [PubMed - indexed for MEDLINE]Related articlesFree article