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    Results: 1 to 50 of 109

    1.

    Diabetic retinopathy is associated with bone marrow neuropathy and a depressed peripheral clock.

    Busik JV, Tikhonenko M, Bhatwadekar A, Opreanu M, Yakubova N, Caballero S, Player D, Nakagawa T, Afzal A, Kielczewski J, Sochacki A, Hasty S, Calzi SL, Kim S, Duclas SK, Segal MS, Guberski DL, Esselman WJ, Boulton ME, Grant MB.

    J Exp Med. 2009 Nov 23. [Epub ahead of print]PMID: 19934019 [PubMed - as supplied by publisher]

    2.

    Insulin-like growth factor binding protein-3 mediates vascular repair by enhancing nitric oxide generation.

    Kielczewski JL, Jarajapu YP, McFarland EL, Cai J, Afzal A, Calzi SL, Chang KH, Lydic T, Shaw LC, Busik J, Hughes J, Cardounel AJ, Wilson K, Lyons TJ, Boulton ME, Mames RN, Chan-Ling T, Grant MB.

    Circ Res. 2009 Oct 23;105(9):897-905. Epub 2009 Sep 17.PMID: 19762684 [PubMed - indexed for MEDLINE]Related articles

    3.

    Targeting retinal and choroid neovascularization using the small molecule inhibitor carboxyamidotriazole.

    Afzal A, Caballero S, Palii SS, Jurczyk S, Pardue M, Geroski D, Edelhauser H, Hochhaus G, Kim M, Franklin A, Shapiro G, Grant MB.

    Brain Res Bull. 2009 Aug 11. [Epub ahead of print]PMID: 19679174 [PubMed - as supplied by publisher]Related articles

    4.

    Delivery of Antioxidant Enzyme Genes Protects Against Ischemia/Reperfusion-Induced Injury to Retinal Microvasculature.

    Chen B, Caballero S, Seo S, Grant MB, Lewin AS.

    Invest Ophthalmol Vis Sci. 2009 Jul 23. [Epub ahead of print]PMID: 19628743 [PubMed - as supplied by publisher]Related articles

    5.

    Regulation of adult hematopoietic stem cells fate for enhanced tissue-specific repair.

    Sengupta N, Caballero S, Sullivan SM, Chang LJ, Afzal A, Li Calzi S, Kielczewski JL, Prabarakan S, Ellis EA, Moldovan L, Moldovan NI, Boulton ME, Grant MB.

    Mol Ther. 2009 Sep;17(9):1594-604. Epub 2009 Jul 7.PMID: 19584817 [PubMed - indexed for MEDLINE]Related articles

    6.

    Retinal endothelial cell apoptosis stimulates recruitment of endothelial progenitor cells.

    Bhatwadekar AD, Glenn JV, Curtis TM, Grant MB, Stitt AW, Gardiner TA.

    Invest Ophthalmol Vis Sci. 2009 Oct;50(10):4967-73. Epub 2009 May 27.PMID: 19474402 [PubMed - indexed for MEDLINE]Related articles

    7.

    Labeling of stem cells with monocrystalline iron oxide for tracking and localization by magnetic resonance imaging.

    Li Calzi S, Kent DL, Chang KH, Padgett KR, Afzal A, Chandra SB, Caballero S, English D, Garlington W, Hiscott PS, Sheridan CM, Grant MB, Forder JR.

    Microvasc Res. 2009 Jun;78(1):132-9. Epub 2009 Apr 5.PMID: 19345699 [PubMed - indexed for MEDLINE]Related articles

    8.

    Lowering blood pressure blocks mesangiolysis and mesangial nodules, but not tubulointerstitial injury, in diabetic eNOS knockout mice.

    Kosugi T, Heinig M, Nakayama T, Connor T, Yuzawa Y, Li Q, Hauswirth WW, Grant MB, Croker BP, Campbell-Thompson M, Zhang L, Atkinson MA, Segal MS, Nakagawa T.

    Am J Pathol. 2009 Apr;174(4):1221-9. Epub 2009 Feb 26.PMID: 19246639 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    The role of ACAID and CD4+CD25+FOXP3+ regulatory T cells on CTL function against MHC alloantigens.

    Saban DR, Cornelius J, Masli S, Schwartzkopff J, Doyle M, Chauhan SK, Peck AB, Grant MB.

    Mol Vis. 2008;14:2435-42. Epub 2008 Dec 19.PMID: 19104677 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Anti-sphingosine-1-phosphate monoclonal antibodies inhibit angiogenesis and sub-retinal fibrosis in a murine model of laser-induced choroidal neovascularization.

    Caballero S, Swaney J, Moreno K, Afzal A, Kielczewski J, Stoller G, Cavalli A, Garland W, Hansen G, Sabbadini R, Grant MB.

    Exp Eye Res. 2009 Mar;88(3):367-77. Epub 2008 Aug 6.PMID: 18723015 [PubMed - indexed for MEDLINE]Related articles

    11.

    Inhibition of protein kinase CK2 suppresses angiogenesis and hematopoietic stem cell recruitment to retinal neovascularization sites.

    Kramerov AA, Saghizadeh M, Caballero S, Shaw LC, Li Calzi S, Bretner M, Montenarh M, Pinna LA, Grant MB, Ljubimov AV.

    Mol Cell Biochem. 2008 Sep;316(1-2):177-86. Epub 2008 Jul 9.PMID: 18612802 [PubMed - indexed for MEDLINE]Related articles

    12.

    The pivotal role of VEGF on glomerular macrophage infiltration in advanced diabetic nephropathy.

    Sato W, Kosugi T, Zhang L, Roncal CA, Heinig M, Campbell-Thompson M, Yuzawa Y, Atkinson MA, Grant MB, Croker BP, Nakagawa T.

    Lab Invest. 2008 Sep;88(9):949-61. Epub 2008 Jul 7.PMID: 18607348 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Nonpeptide somatostatin receptor agonists specifically target ocular neovascularization via the somatostatin type 2 receptor.

    Palii SS, Afzal A, Shaw LC, Pan H, Caballero S, Miller RC, Jurczyk S, Reubi JC, Tan Y, Hochhaus G, Edelhauser H, Geroski D, Shapiro G, Grant MB.

    Invest Ophthalmol Vis Sci. 2008 Nov;49(11):5094-102. Epub 2008 Jul 3.PMID: 18599562 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Carbon monoxide and nitric oxide mediate cytoskeletal reorganization in microvascular cells via vasodilator-stimulated phosphoprotein phosphorylation: evidence for blunted responsiveness in diabetes.

    Li Calzi S, Purich DL, Chang KH, Afzal A, Nakagawa T, Busik JV, Agarwal A, Segal MS, Grant MB.

    Diabetes. 2008 Sep;57(9):2488-94. Epub 2008 Jun 16.PMID: 18559661 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Hyperglycemia-induced reactive oxygen species toxicity to endothelial cells is dependent on paracrine mediators.

    Busik JV, Mohr S, Grant MB.

    Diabetes. 2008 Jul;57(7):1952-65. Epub 2008 Apr 16.PMID: 18420487 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Characterization of intraocular immunopathology following intracameral inoculation with alloantigen.

    Saban DR, Elder IA, Nguyen CQ, Smith WC, Timmers AM, Grant MB, Peck AB.

    Mol Vis. 2008 Mar 26;14:615-24.PMID: 18385797 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    gamma-Secretase: a multifaceted regulator of angiogenesis.

    Boulton ME, Cai J, Grant MB.

    J Cell Mol Med. 2008 Jun;12(3):781-95. Epub 2008 Feb 8. Review.PMID: 18266961 [PubMed - indexed for MEDLINE]Related articles

    18.

    Erythropoietin: when liability becomes asset in neurovascular repair.

    Grant MB, Boulton ME, Ljubimov AV.

    J Clin Invest. 2008 Feb;118(2):467-70.PMID: 18219388 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Gamma-secretase regulates VEGFR-1 signalling in vascular endothelium and RPE.

    Boulton ME, Cai J, Grant MB, Zhang Y.

    Adv Exp Med Biol. 2008;613:313-9. Review.PMID: 18188959 [PubMed - indexed for MEDLINE]Related articles

    20.

    Studies with an orally bioavailable alpha V integrin antagonist in animal models of ocular vasculopathy: retinal neovascularization in mice and retinal vascular permeability in diabetic rats.

    Santulli RJ, Kinney WA, Ghosh S, Decorte BL, Liu L, Tuman RW, Zhou Z, Huebert N, Bursell SE, Clermont AC, Grant MB, Shaw LC, Mousa SA, Galemmo RA Jr, Johnson DL, Maryanoff BE, Damiano BP.

    J Pharmacol Exp Ther. 2008 Mar;324(3):894-901. Epub 2007 Dec 14.PMID: 18083913 [PubMed - indexed for MEDLINE]Related articlesFree article

    21.

    Myogenic tone and reactivity of cerebral arteries in type II diabetic BBZDR/Wor rat.

    Jarajapu YP, Guberski DL, Grant MB, Knot HJ.

    Eur J Pharmacol. 2008 Jan 28;579(1-3):298-307. Epub 2007 Oct 25.PMID: 18036520 [PubMed - indexed for MEDLINE]Related articles

    22.

    Retinal and choroidal microangiopathies: therapeutic opportunities.

    Afzal A, Shaw LC, Ljubimov AV, Boulton ME, Segal MS, Grant MB.

    Microvasc Res. 2007 Sep-Nov;74(2-3):131-44. Epub 2007 May 21. Review.PMID: 17585951 [PubMed - indexed for MEDLINE]Related articles

    23.

    IGF binding protein-3 regulates hematopoietic stem cell and endothelial precursor cell function during vascular development.

    Chang KH, Chan-Ling T, McFarland EL, Afzal A, Pan H, Baxter LC, Shaw LC, Caballero S, Sengupta N, Li Calzi S, Sullivan SM, Grant MB.

    Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10595-600. Epub 2007 Jun 13.PMID: 17567755 [PubMed - indexed for MEDLINE]Related articlesFree article

    24.

    Generation of functional hemangioblasts from human embryonic stem cells.

    Lu SJ, Feng Q, Caballero S, Chen Y, Moore MA, Grant MB, Lanza R.

    Nat Methods. 2007 Jun;4(6):501-9. Epub 2007 May 7.PMID: 17486087 [PubMed - indexed for MEDLINE]Related articles

    25.

    Adenoviruses increase endothelial cell proliferation, migration, and tube formation: partial reversal by the focal adhesion kinase inhibitor, FRNK.

    Kornberg LJ, Grant MB.

    Microvasc Res. 2007 May;73(3):157-62. Epub 2007 Feb 23.PMID: 17407784 [PubMed - indexed for MEDLINE]Related articlesFree article

    26.

    Ischemic vascular damage can be repaired by healthy, but not diabetic, endothelial progenitor cells.

    Caballero S, Sengupta N, Afzal A, Chang KH, Li Calzi S, Guberski DL, Kern TS, Grant MB.

    Diabetes. 2007 Apr;56(4):960-7.PMID: 17395742 [PubMed - indexed for MEDLINE]Related articlesFree article

    27.

    Stromal cell-derived factor 1 promotes angiogenesis via a heme oxygenase 1-dependent mechanism.

    Deshane J, Chen S, Caballero S, Grochot-Przeczek A, Was H, Li Calzi S, Lach R, Hock TD, Chen B, Hill-Kapturczak N, Siegal GP, Dulak J, Jozkowicz A, Grant MB, Agarwal A.

    J Exp Med. 2007 Mar 19;204(3):605-18. Epub 2007 Mar 5.PMID: 17339405 [PubMed - indexed for MEDLINE]Related articlesFree article

    28.

    Medical treatment of diabetic retinopathy with somatostatin analogues.

    Palii SS, Caballero S Jr, Shapiro G, Grant MB.

    Expert Opin Investig Drugs. 2007 Jan;16(1):73-82. Review.PMID: 17155855 [PubMed - indexed for MEDLINE]Related articles

    29.

    Characteristics of myogenic tone in the rat ophthalmic artery.

    Ito I, Jarajapu YP, Grant MB, Knot HJ.

    Am J Physiol Heart Circ Physiol. 2007 Jan;292(1):H360-8. Epub 2006 Aug 18.PMID: 16920804 [PubMed - indexed for MEDLINE]Related articlesFree article

    30.

    The dipeptide Arg-Gln inhibits retinal neovascularization in the mouse model of oxygen-induced retinopathy.

    Neu J, Afzal A, Pan H, Gallego E, Li N, Li Calzi S, Caballero S, Spoerri PE, Shaw LC, Grant MB.

    Invest Ophthalmol Vis Sci. 2006 Jul;47(7):3151-5.PMID: 16799062 [PubMed - indexed for MEDLINE]Related articlesFree article

    31.

    Proceedings of the Third International Symposium on Retinopathy of Prematurity: an update on ROP from the lab to the nursery (November 2003, Anaheim, California).

    Lutty GA, Chan-Ling T, Phelps DL, Adamis AP, Berns KI, Chan CK, Cole CH, D'Amore PA, Das A, Deng WT, Dobson V, Flynn JT, Friedlander M, Fulton A, Good WV, Grant MB, Hansen R, Hauswirth WW, Hardy RJ, Hinton DR, Hughes S, McLeod DS, Palmer EA, Patz A, Penn JS, Raisler BJ, Repka MX, Saint-Geniez M, Shaw LC, Shima DT, Smith BT, Smith LE, Tahija SG, Tasman W, Trese MT.

    Mol Vis. 2006 May 23;12:532-80.PMID: 16735995 [PubMed - indexed for MEDLINE]Related articlesFree article

    32.

    Expression of protein kinase CK2 in astroglial cells of normal and neovascularized retina.

    Kramerov AA, Saghizadeh M, Pan H, Kabosova A, Montenarh M, Ahmed K, Penn JS, Chan CK, Hinton DR, Grant MB, Ljubimov AV.

    Am J Pathol. 2006 May;168(5):1722-36.PMID: 16651637 [PubMed - indexed for MEDLINE]Related articlesFree article

    33.

    Bone marrow-derived cells home to and regenerate retinal pigment epithelium after injury.

    Harris JR, Brown GA, Jorgensen M, Kaushal S, Ellis EA, Grant MB, Scott EW.

    Invest Ophthalmol Vis Sci. 2006 May;47(5):2108-13.PMID: 16639022 [PubMed - indexed for MEDLINE]Related articlesFree article

    34.

    Hematopoietic stem cells provide repair functions after laser-induced Bruch's membrane rupture model of choroidal neovascularization.

    Chan-Ling T, Baxter L, Afzal A, Sengupta N, Caballero S, Rosinova E, Grant MB.

    Am J Pathol. 2006 Mar;168(3):1031-44.PMID: 16507916 [PubMed - indexed for MEDLINE]Related articlesFree article

    35.

    Effects of VEGFR-1, VEGFR-2, and IGF-IR hammerhead ribozymes on glucose-mediated tight junction expression in cultured human retinal endothelial cells.

    Spoerri PE, Afzal A, Li Calzi S, Shaw LC, Cai J, Pan H, Boulton M, Grant MB.

    Mol Vis. 2006 Jan 12;12:32-42.PMID: 16446700 [PubMed - indexed for MEDLINE]Related articlesFree article

    36.

    Proliferating endothelial cell-specific expression of IGF-I receptor ribozyme inhibits retinal neovascularization.

    Shaw LC, Pan H, Afzal A, Calzi SL, Spoerri PE, Sullivan SM, Grant MB.

    Gene Ther. 2006 May;13(9):752-60.PMID: 16437130 [PubMed - indexed for MEDLINE]Related articles

    37.

    Myogenic tone and reactivity of rat ophthalmic artery in acute exposure to high glucose and in a type II diabetic model.

    Ito I, Jarajapu YP, Guberski DL, Grant MB, Knot HJ.

    Invest Ophthalmol Vis Sci. 2006 Feb;47(2):683-92.PMID: 16431968 [PubMed - indexed for MEDLINE]Related articlesFree article

    38.

    Nitric oxide cytoskeletal-induced alterations reverse the endothelial progenitor cell migratory defect associated with diabetes.

    Segal MS, Shah R, Afzal A, Perrault CM, Chang K, Schuler A, Beem E, Shaw LC, Li Calzi S, Harrison JK, Tran-Son-Tay R, Grant MB.

    Diabetes. 2006 Jan;55(1):102-9.PMID: 16380482 [PubMed - indexed for MEDLINE]Related articlesFree article

    39.

    Nitric oxide synthases modulate progenitor and resident endothelial cell behavior in galactosemia.

    Ellis EA, Sengupta N, Caballero S, Guthrie SM, Mames RN, Grant MB.

    Antioxid Redox Signal. 2005 Nov-Dec;7(11-12):1413-22.PMID: 16356104 [PubMed - indexed for MEDLINE]Related articles

    40.

    Pigment epithelium-derived factor inhibits angiogenesis via regulated intracellular proteolysis of vascular endothelial growth factor receptor 1.

    Cai J, Jiang WG, Grant MB, Boulton M.

    J Biol Chem. 2006 Feb 10;281(6):3604-13. Epub 2005 Dec 8.PMID: 16339148 [PubMed - indexed for MEDLINE]Related articlesFree article

    41.

    The potential role of octreotide in the treatment of diabetic retinopathy.

    Grant MB, Caballero S Jr.

    Treat Endocrinol. 2005;4(4):199-203. Review.PMID: 16053337 [PubMed - indexed for MEDLINE]Related articles

    42.

    P450 in the angiogenesis affair: the unusual suspect.

    Ljubimov AV, Grant MB.

    Am J Pathol. 2005 Feb;166(2):341-4. No abstract available. PMID: 15681818 [PubMed - indexed for MEDLINE]Related articlesFree article

    43.

    SDF-1 is both necessary and sufficient to promote proliferative retinopathy.

    Butler JM, Guthrie SM, Koc M, Afzal A, Caballero S, Brooks HL, Mames RN, Segal MS, Grant MB, Scott EW.

    J Clin Invest. 2005 Jan;115(1):86-93.PMID: 15630447 [PubMed - indexed for MEDLINE]Related articlesFree article

    44.

    Preventing stem cell incorporation into choroidal neovascularization by targeting homing and attachment factors.

    Sengupta N, Caballero S, Mames RN, Timmers AM, Saban D, Grant MB.

    Invest Ophthalmol Vis Sci. 2005 Jan;46(1):343-8.PMID: 15623794 [PubMed - indexed for MEDLINE]Related articlesFree article

    45.

    Vitreous levels of vascular endothelial growth factor and stromal-derived factor 1 in patients with diabetic retinopathy and cystoid macular edema before and after intraocular injection of triamcinolone.

    Brooks HL Jr, Caballero S Jr, Newell CK, Steinmetz RL, Watson D, Segal MS, Harrison JK, Scott EW, Grant MB.

    Arch Ophthalmol. 2004 Dec;122(12):1801-7.PMID: 15596583 [PubMed - indexed for MEDLINE]Related articles

    46.

    Involvement of protein kinase CK2 in angiogenesis and retinal neovascularization.

    Ljubimov AV, Caballero S, Aoki AM, Pinna LA, Grant MB, Castellon R.

    Invest Ophthalmol Vis Sci. 2004 Dec;45(12):4583-91.PMID: 15557471 [PubMed - indexed for MEDLINE]Related articlesFree article

    47.

    Focal adhesion kinase overexpression induces enhanced pathological retinal angiogenesis.

    Kornberg LJ, Shaw LC, Spoerri PE, Caballero S, Grant MB.

    Invest Ophthalmol Vis Sci. 2004 Dec;45(12):4463-9.PMID: 15557455 [PubMed - indexed for MEDLINE]Related articlesFree article

    48.

    The nitric oxide pathway modulates hemangioblast activity of adult hematopoietic stem cells.

    Guthrie SM, Curtis LM, Mames RN, Simon GG, Grant MB, Scott EW.

    Blood. 2005 Mar 1;105(5):1916-22. Epub 2004 Nov 16.PMID: 15546953 [PubMed - indexed for MEDLINE]Related articlesFree article

    49.

    Analysis of the vascular potential of hematopoietic stem cells.

    Guthrie SM, Caballero S, Mames RN, Grant MB, Scott EW.

    Methods Mol Med. 2005;105:369-80.PMID: 15492408 [PubMed - indexed for MEDLINE]Related articles

    50.

    The role of growth factors in the pathogenesis of diabetic retinopathy.

    Grant MB, Afzal A, Spoerri P, Pan H, Shaw LC, Mames RN.

    Expert Opin Investig Drugs. 2004 Oct;13(10):1275-93. Review.PMID: 15461557 [PubMed - indexed for MEDLINE]Related articles

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