PubMed

Surface translocation and tri-iodothyronine uptake of mutant MCT8 proteins are cell type-dependent.

Kinne A, Roth S, Biebermann H, Köhrle J, Grüters A, Schweizer U.

J Mol Endocrinol. 2009 Dec;43(6):263-71. Epub 2009 Jul 31.PMID: 19648159 [PubMed - in process]Related articles

Neuronal 3',3,5-triiodothyronine (T3) uptake and behavioral phenotype of mice deficient in Mct8, the neuronal T3 transporter mutated in Allan-Herndon-Dudley syndrome.

Wirth EK, Roth S, Blechschmidt C, Hölter SM, Becker L, Racz I, Zimmer A, Klopstock T, Gailus-Durner V, Fuchs H, Wurst W, Naumann T, Bräuer A, de Angelis MH, Köhrle J, Grüters A, Schweizer U.

J Neurosci. 2009 Jul 29;29(30):9439-49.PMID: 19641107 [PubMed - indexed for MEDLINE]Related articles

The spectrum of phenotypes associated with mutations in steroidogenic factor 1 (SF-1, NR5A1, Ad4BP) includes severe penoscrotal hypospadias in 46,XY males without adrenal insufficiency.

Köhler B, Lin L, Mazen I, Cetindag C, Biebermann H, Akkurt I, Rossi R, Hiort O, Grüters A, Achermann JC.

Eur J Endocrinol. 2009 Aug;161(2):237-42. Epub 2009 May 13.PMID: 19439508 [PubMed - indexed for MEDLINE]Related articlesFree article

Expanded clinical spectrum in hepatocyte nuclear factor 1b-maturity-onset diabetes of the young.

Raile K, Klopocki E, Holder M, Wessel T, Galler A, Deiss D, Müller D, Riebel T, Horn D, Maringa M, Weber J, Ullmann R, Grüters A.

J Clin Endocrinol Metab. 2009 Jul;94(7):2658-64. Epub 2009 May 5.PMID: 19417042 [PubMed - indexed for MEDLINE]Related articles

Is there a further acceleration in the age at onset of menarche? A cross-sectional study in 1840 school children focusing on age and bodyweight at the onset of menarche.

Bau AM, Ernert A, Schenk L, Wiegand S, Martus P, Grüters A, Krude H.

Eur J Endocrinol. 2009 Jan;160(1):107-13. Epub 2008 Oct 30.PMID: 18974233 [PubMed - indexed for MEDLINE]Related articles

HNF1B abnormality (mature-onset diabetes of the young 5) in children and adolescents: high prevalence in autoantibody-negative type 1 diabetes with kidney defects.

Raile K, Klopocki E, Wessel T, Deiss D, Horn D, Müller D, Ullmann R, Grüters A.

Diabetes Care. 2008 Nov;31(11):e83. No abstract available. PMID: 18955710 [PubMed - indexed for MEDLINE]Related articlesFree article

Mutations in the iodotyrosine deiodinase gene and hypothyroidism.

Moreno JC, Klootwijk W, van Toor H, Pinto G, D'Alessandro M, Lèger A, Goudie D, Polak M, Grüters A, Visser TJ.

N Engl J Med. 2008 Apr 24;358(17):1811-8.PMID: 18434651 [PubMed - indexed for MEDLINE]Related articlesFree article

Update on the management of congenital hypothyroidism.

Grüters A, Krude H.

Horm Res. 2007;68 Suppl 5:107-11. Epub 2007 Dec 10. Review.PMID: 18174723 [PubMed - indexed for MEDLINE]Related articles

Endocrine disruptors and the thyroid gland--a combined in vitro and in vivo analysis of potential new biomarkers.

Schmutzler C, Gotthardt I, Hofmann PJ, Radovic B, Kovacs G, Stemmler L, Nobis I, Bacinski A, Mentrup B, Ambrugger P, Grüters A, Malendowicz LK, Christoffel J, Jarry H, Seidlovà-Wuttke D, Wuttke W, Köhrle J.

Environ Health Perspect. 2007 Dec;115 Suppl 1:77-83.PMID: 18174954 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced 11beta-hydroxysteroid dehydrogenase type 1 activity in obese boys.

Wiegand S, Richardt A, Remer T, Wudy SA, Tomlinson JW, Hughes B, Grüters A, Stewart PM, Strasburger CJ, Quinkler M.

Eur J Endocrinol. 2007 Sep;157(3):319-24.PMID: 17766714 [PubMed - indexed for MEDLINE]Related articlesFree article

Five novel mutations in steroidogenic factor 1 (SF1, NR5A1) in 46,XY patients with severe underandrogenization but without adrenal insufficiency.

Köhler B, Lin L, Ferraz-de-Souza B, Wieacker P, Heidemann P, Schröder V, Biebermann H, Schnabel D, Grüters A, Achermann JC.

Hum Mutat. 2008 Jan;29(1):59-64.PMID: 17694559 [PubMed - indexed for MEDLINE]Related articlesFree article

Thyroid hormone transporter defects.

Grüters A.

Endocr Dev. 2007;10:118-26. Review.PMID: 17684393 [PubMed - indexed for MEDLINE]Related articles

Evolutionary aspects in evaluating mutations in the melanocortin 4 receptor.

Stäubert C, Tarnow P, Brumm H, Pitra C, Gudermann T, Grüters A, Schöneberg T, Biebermann H, Römpler H.

Endocrinology. 2007 Oct;148(10):4642-8. Epub 2007 Jul 12.PMID: 17628007 [PubMed - indexed for MEDLINE]Related articlesFree article

Screening for mutations in transcription factors in a Czech cohort of 170 patients with congenital and early-onset hypothyroidism: identification of a novel PAX8 mutation in dominantly inherited early-onset non-autoimmune hypothyroidism.

Al Taji E, Biebermann H, Límanová Z, Hníková O, Zikmund J, Dame C, Grüters A, Lebl J, Krude H.

Eur J Endocrinol. 2007 May;156(5):521-9.PMID: 17468187 [PubMed - indexed for MEDLINE]Related articlesFree article

The ultraviolet filter benzophenone 2 interferes with the thyroid hormone axis in rats and is a potent in vitro inhibitor of human recombinant thyroid peroxidase.

Schmutzler C, Bacinski A, Gotthardt I, Huhne K, Ambrugger P, Klammer H, Schlecht C, Hoang-Vu C, Grüters A, Wuttke W, Jarry H, Köhrle J.

Endocrinology. 2007 Jun;148(6):2835-44. Epub 2007 Mar 22.PMID: 17379648 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional analysis of monocarboxylate transporter 8 mutations identified in patients with X-linked psychomotor retardation and elevated serum triiodothyronine.

Jansen J, Friesema EC, Kester MH, Milici C, Reeser M, Grüters A, Barrett TG, Mancilla EE, Svensson J, Wemeau JL, Busi da Silva Canalli MH, Lundgren J, McEntagart ME, Hopper N, Arts WF, Visser TJ.

J Clin Endocrinol Metab. 2007 Jun;92(6):2378-81. Epub 2007 Mar 13.PMID: 17356046 [PubMed - indexed for MEDLINE]Related articlesFree article

[Diagnostic classification of mental disorders in infants and toddlers age 0 to 5]

Wiefel A, Titze K, Kuntze L, Winter M, Seither C, Witte B, Lenz K, Grüters A, Lehmkuhl U.

Prax Kinderpsychol Kinderpsychiatr. 2007;56(1):59-81. Review. German. PMID: 17323818 [PubMed - indexed for MEDLINE]Related articles

Homozygosity mapping in consanguineous families reveals extreme heterogeneity of non-syndromic autosomal recessive mental retardation and identifies 8 novel gene loci.

Najmabadi H, Motazacker MM, Garshasbi M, Kahrizi K, Tzschach A, Chen W, Behjati F, Hadavi V, Nieh SE, Abedini SS, Vazifehmand R, Firouzabadi SG, Jamali P, Falah M, Seifati SM, Grüters A, Lenzner S, Jensen LR, Rüschendorf F, Kuss AW, Ropers HH.

Hum Genet. 2007 Mar;121(1):43-8. Epub 2006 Nov 21.PMID: 17120046 [PubMed - indexed for MEDLINE]Related articles

Arteries define the position of the thyroid gland during its developmental relocalisation.

Alt B, Elsalini OA, Schrumpf P, Haufs N, Lawson ND, Schwabe GC, Mundlos S, Grüters A, Krude H, Rohr KB.

Development. 2006 Oct;133(19):3797-804.PMID: 16968815 [PubMed - indexed for MEDLINE]Related articlesFree article

A role for beta-melanocyte-stimulating hormone in human body-weight regulation.

Biebermann H, Castañeda TR, van Landeghem F, von Deimling A, Escher F, Brabant G, Hebebrand J, Hinney A, Tschöp MH, Grüters A, Krude H.

Cell Metab. 2006 Feb;3(2):141-6.PMID: 16459315 [PubMed - indexed for MEDLINE]Related articles

Impaired glucose tolerance and type 2 diabetes mellitus: a new field for pediatrics in Europe.

Wiegand S, Dannemann A, Krude H, Grüters A.

Int J Obes (Lond). 2005 Sep;29 Suppl 2:S136-42.PMID: 16385766 [PubMed - indexed for MEDLINE]Related articles

Hypothalamic and gonadal components of hypogonadism in boys with Prader-Labhart- Willi syndrome.

Eiholzer U, l'Allemand D, Rousson V, Schlumpf M, Gasser T, Girard J, Grüters A, Simoni M.

J Clin Endocrinol Metab. 2006 Mar;91(3):892-8. Epub 2005 Dec 13.PMID: 16352691 [PubMed - indexed for MEDLINE]Related articlesFree article

MC4R oligomerizes independently of extracellular cysteine residues.

Elsner A, Tarnow P, Schaefer M, Ambrugger P, Krude H, Grüters A, Biebermann H.

Peptides. 2006 Feb;27(2):372-9. Epub 2005 Nov 9.PMID: 16289450 [PubMed - indexed for MEDLINE]Related articles

[The pediatric-to-adult transit clinic as a quality-securing measure in endocrinological diseases]

Grüters A.

MMW Fortschr Med. 2005 Mar 10;147(10):29, 31-2. Review. German. PMID: 15803780 [PubMed - indexed for MEDLINE]Related articles

[Who needs what? New approaches to multidisciplinary diagnostics and therapy for adipose children and youths in a multiethnic city]

Wiegand S, Dannemann A, Vahabzadeh Z, Ernst M, Krude H, Grüters A.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2005 Mar;48(3):307-14. German. PMID: 15768303 [PubMed - indexed for MEDLINE]Related articles

Childhood obesity.

Speiser PW, Rudolf MC, Anhalt H, Camacho-Hubner C, Chiarelli F, Eliakim A, Freemark M, Gruters A, Hershkovitz E, Iughetti L, Krude H, Latzer Y, Lustig RH, Pescovitz OH, Pinhas-Hamiel O, Rogol AD, Shalitin S, Sultan C, Stein D, Vardi P, Werther GA, Zadik Z, Zuckerman-Levin N, Hochberg Z; Obesity Consensus Working Group.

J Clin Endocrinol Metab. 2005 Mar;90(3):1871-87. Epub 2004 Dec 14. Review.PMID: 15598688 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular genetic defects in congenital hypothyroidism.

Grüters A, Krude H, Biebermann H.

Eur J Endocrinol. 2004 Nov;151 Suppl 3:U39-44. Review.PMID: 15554885 [PubMed - indexed for MEDLINE]Related articlesFree article

Endocrine active compounds affect thyrotropin and thyroid hormone levels in serum as well as endpoints of thyroid hormone action in liver, heart and kidney.

Schmutzler C, Hamann I, Hofmann PJ, Kovacs G, Stemmler L, Mentrup B, Schomburg L, Ambrugger P, Grüters A, Seidlova-Wuttke D, Jarry H, Wuttke W, Köhrle J.

Toxicology. 2004 Dec 1;205(1-2):95-102.PMID: 15458794 [PubMed - indexed for MEDLINE]Related articles

The use of L-T4 as liquid solution improves the practicability and individualized dosage in newborns and infants with congenital hypothyroidism.

von Heppe JH, Krude H, L'Allemand D, Schnabel D, Grüters A.

J Pediatr Endocrinol Metab. 2004 Jul;17(7):967-74.PMID: 15301044 [PubMed - indexed for MEDLINE]Related articles

Type 2 diabetes and impaired glucose tolerance in European children and adolescents with obesity -- a problem that is no longer restricted to minority groups.

Wiegand S, Maikowski U, Blankenstein O, Biebermann H, Tarnow P, Grüters A.

Eur J Endocrinol. 2004 Aug;151(2):199-206.PMID: 15296475 [PubMed - indexed for MEDLINE]Related articlesFree article

[Characteristic features of autoimmune thyroid disease in children]

Grüters A.

Z Arztl Fortbild Qualitatssich. 2004 May;98 Suppl 5:67-71. Review. German. PMID: 15255316 [PubMed - indexed for MEDLINE]Related articles

Minimal inflammation, acute phase response and avoidance of misclassification of vitamin A and iron status in infants--importance of a high-sensitivity C-reactive protein (CRP) assay.

Abraham K, Müller C, Grüters A, Wahn U, Schweigert FJ.

Int J Vitam Nutr Res. 2003 Nov;73(6):423-30.PMID: 14743546 [PubMed - indexed for MEDLINE]Related articles

Autosomal-dominant mode of inheritance of a melanocortin-4 receptor mutation in a patient with severe early-onset obesity is due to a dominant-negative effect caused by receptor dimerization.

Biebermann H, Krude H, Elsner A, Chubanov V, Gudermann T, Grüters A.

Diabetes. 2003 Dec;52(12):2984-8.PMID: 14633860 [PubMed - indexed for MEDLINE]Related articlesFree article

Obesity due to proopiomelanocortin deficiency: three new cases and treatment trials with thyroid hormone and ACTH4-10.

Krude H, Biebermann H, Schnabel D, Tansek MZ, Theunissen P, Mullis PE, Grüters A.

J Clin Endocrinol Metab. 2003 Oct;88(10):4633-40.PMID: 14557433 [PubMed - indexed for MEDLINE]Related articlesFree article

[Hypothyroidism in dizygotic premature twins due to excessive prepartal vaginal iodine application]

Müther S, Krude H, Jäger R, Rhode W, Grüters A, Rossi R.

Zentralbl Gynakol. 2003 Jun;125(6):226-8. German. PMID: 14556121 [PubMed - indexed for MEDLINE]Related articles

Mutationally induced disulfide bond formation within the third extracellular loop causes melanocortin 4 receptor inactivation in patients with obesity.

Tarnow P, Schoneberg T, Krude H, Gruters A, Biebermann H.

J Biol Chem. 2003 Dec 5;278(49):48666-73. Epub 2003 Sep 22.PMID: 14504270 [PubMed - indexed for MEDLINE]Related articlesFree article

Mutations in the human proopiomelanocortin gene.

Krude H, Biebermann H, Gruters A.

Ann N Y Acad Sci. 2003 Jun;994:233-9. Review.PMID: 12851321 [PubMed - indexed for MEDLINE]Related articles

The prevalence of anti-thyroid peroxidase antibodies and autoimmune thyroiditis in children and adolescents in an iodine replete area.

Kabelitz M, Liesenkötter KP, Stach B, Willgerodt H, Stäblein W, Singendonk W, Jäger-Roman E, Litzenbörger H, Ehnert B, Grüters A.

Eur J Endocrinol. 2003 Mar;148(3):301-7.PMID: 12611610 [PubMed - indexed for MEDLINE]Related articlesFree article

Neonatal thyroid disorders.

Grüters A, Biebermann H, Krude H.

Horm Res. 2003;59 Suppl 1:24-9. Review.PMID: 12566717 [PubMed - indexed for MEDLINE]Related articles

Aminoglycoside pretreatment partially restores the function of truncated V(2) vasopressin receptors found in patients with nephrogenic diabetes insipidus.

Schulz A, Sangkuhl K, Lennert T, Wigger M, Price DA, Nuuja A, Grüters A, Schultz G, Schöneberg T.

J Clin Endocrinol Metab. 2002 Nov;87(11):5247-57.PMID: 12414899 [PubMed - indexed for MEDLINE]Related articlesFree article

Congenital central hypothyroidism due to homozygous thyrotropin beta 313 Delta T mutation is caused by a Founder effect.

Brumm H, Pfeufer A, Biebermann H, Schnabel D, Deiss D, Grüters A.

J Clin Endocrinol Metab. 2002 Oct;87(10):4811-6.PMID: 12364478 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term consequences of congenital hypothyroidism in the era of screening programmes.

Grüters A, Jenner A, Krude H.

Best Pract Res Clin Endocrinol Metab. 2002 Jun;16(2):369-82. Review.PMID: 12064898 [PubMed - indexed for MEDLINE]Related articles

Mutations in TITF-1 are associated with benign hereditary chorea.

Breedveld GJ, van Dongen JW, Danesino C, Guala A, Percy AK, Dure LS, Harper P, Lazarou LP, van der Linde H, Joosse M, Grüters A, MacDonald ME, de Vries BB, Arts WF, Oostra BA, Krude H, Heutink P.

Hum Mol Genet. 2002 Apr 15;11(8):971-9.PMID: 11971878 [PubMed - indexed for MEDLINE]Related articlesFree article

[Gene, fast food and no motion. Causes of childhood obesity]

Grüters A, Wiegand S, Krude H.

MMW Fortschr Med. 2002 Feb 28;144(9):34-6. German. PMID: 11921649 [PubMed - indexed for MEDLINE]Related articles

Associations between body mass, leptin, IGF-I and circulating adrenal androgens in children with obesity and premature adrenarche.

l'Allemand D, Schmidt S, Rousson V, Brabant G, Gasser T, Grüters A.

Eur J Endocrinol. 2002 Apr;146(4):537-43.PMID: 11916623 [PubMed - indexed for MEDLINE]Related articlesFree article

Choreoathetosis, hypothyroidism, and pulmonary alterations due to human NKX2-1 haploinsufficiency.

Krude H, Schütz B, Biebermann H, von Moers A, Schnabel D, Neitzel H, Tönnies H, Weise D, Lafferty A, Schwarz S, DeFelice M, von Deimling A, van Landeghem F, DiLauro R, Grüters A.

J Clin Invest. 2002 Feb;109(4):475-80.PMID: 11854319 [PubMed - indexed for MEDLINE]Related articlesFree article

Short stature homeobox-containing gene deletion screening by fluorescence in situ hybridisation in patients with short stature.

Musebeck J, Mohnike K, Beye P, Tönnies H, Neitzel H, Schnabel D, Grüters A, Wieacker PF, Stumm M.

Eur J Pediatr. 2001 Sep;160(9):561-5.PMID: 11585080 [PubMed - indexed for MEDLINE]Related articles

The first activating TSH receptor mutation in transmembrane domain 1 identified in a family with nonautoimmune hyperthyroidism.

Biebermann H, Schöneberg T, Hess C, Germak J, Gudermann T, Grüters A.

J Clin Endocrinol Metab. 2001 Sep;86(9):4429-33.PMID: 11549687 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel mutations of the thyroid peroxidase gene in patients with permanent congenital hypothyroidism.

Ambrugger P, Stoeva I, Biebermann H, Torresani T, Leitner C, Grüters A.

Eur J Endocrinol. 2001 Jul;145(1):19-24.PMID: 11415848 [PubMed - indexed for MEDLINE]Related articlesFree article

[No title available]

Grüters A, Krude H, Biebermann H, Netchine And S Amselem I.

An Esp Pediatr. 2001 May;54(Supl 1):28-30. No abstract available. PMID: 11333501 [PubMed - as supplied by publisher]Free article