PubMed

Candidate genetic analysis of plasma high-density lipoprotein-cholesterol and severity of coronary atherosclerosis.

Chen SN, Cilingiroglu M, Todd J, Lombardi R, Willerson JT, Gotto AM Jr, Ballantyne CM, Marian AJ.

BMC Med Genet. 2009 Oct 30;10:111.PMID: 19878569 [PubMed - in process]Related articlesFree article

Design of the DEFINE trial: determining the EFficacy and tolerability of CETP INhibition with AnacEtrapib.

Cannon CP, Dansky HM, Davidson M, Gotto AM Jr, Brinton EA, Gould AL, Stepanavage M, Liu SX, Shah S, Rubino J, Gibbons P, Hermanowski-Vosatka A, Binkowitz B, Mitchel Y, Barter P; DEFINE investigators.

Am Heart J. 2009 Oct;158(4):513-519.e3.PMID: 19781408 [PubMed - indexed for MEDLINE]Related articles

Effects of increasing high-density lipoprotein cholesterol and decreasing low-density lipoprotein cholesterol on the incidence of first acute coronary events (from the Air Force/Texas Coronary Atherosclerosis Prevention Study).

Cui Y, Watson DJ, Girman CJ, Shapiro DR, Gotto AM, Hiserote P, Clearfield MB.

Am J Cardiol. 2009 Sep 15;104(6):829-34.PMID: 19733719 [PubMed - indexed for MEDLINE]Related articles

The benefits of statins in people without established cardiovascular disease but with cardiovascular risk factors: meta-analysis of randomised controlled trials.

Brugts JJ, Yetgin T, Hoeks SE, Gotto AM, Shepherd J, Westendorp RG, de Craen AJ, Knopp RH, Nakamura H, Ridker P, van Domburg R, Deckers JW.

BMJ. 2009 Jun 30;338:b2376. doi: 10.1136/bmj.b2376. Review.PMID: 19567909 [PubMed - indexed for MEDLINE]Related articlesFree article

Improving lipid goal attainment: is it enough?

Gotto AM Jr.

Circulation. 2009 Jul 7;120(1):3-5. Epub 2009 Jun 22. No abstract available. PMID: 19546383 [PubMed - indexed for MEDLINE]Related articles

Atherosclerosis in LDLR-knockout mice is inhibited, but not reversed, by the PPARgamma ligand pioglitazone.

Nakaya H, Summers BD, Nicholson AC, Gotto AM Jr, Hajjar DP, Han J.

Am J Pathol. 2009 Jun;174(6):2007-14. Epub 2009 May 12.PMID: 19435790 [PubMed - indexed for MEDLINE]Related articles

Pitavastatin suppresses mitogen activated protein kinase-mediated Erg-1 induction in human vascular smooth muscle cells.

Lamon BD, Summers BD, Gotto AM Jr, Hajjar DP.

Eur J Pharmacol. 2009 Mar 15;606(1-3):72-6. Epub 2009 Jan 14.PMID: 19374880 [PubMed - indexed for MEDLINE]Related articles

A randomized trial of rosuvastatin in the prevention of venous thromboembolism.

Glynn RJ, Danielson E, Fonseca FA, Genest J, Gotto AM Jr, Kastelein JJ, Koenig W, Libby P, Lorenzatti AJ, MacFadyen JG, Nordestgaard BG, Shepherd J, Willerson JT, Ridker PM.

N Engl J Med. 2009 Apr 30;360(18):1851-61. Epub 2009 Mar 29.PMID: 19329822 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: a prospective study of the JUPITER trial.

Ridker PM, Danielson E, Fonseca FA, Genest J, Gotto AM Jr, Kastelein JJ, Koenig W, Libby P, Lorenzatti AJ, Macfadyen JG, Nordestgaard BG, Shepherd J, Willerson JT, Glynn RJ; JUPITER Trial Study Group.

Lancet. 2009 Apr 4;373(9670):1175-82. Epub 2009 Mar 28.PMID: 19329177 [PubMed - indexed for MEDLINE]Related articles

The 9p21 susceptibility locus for coronary artery disease and the severity of coronary atherosclerosis.

Chen SN, Ballantyne CM, Gotto AM Jr, Marian AJ.

BMC Cardiovasc Disord. 2009 Jan 27;9:3.PMID: 19173706 [PubMed - indexed for MEDLINE]Related articlesFree article

Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein.

Ridker PM, Danielson E, Fonseca FA, Genest J, Gotto AM Jr, Kastelein JJ, Koenig W, Libby P, Lorenzatti AJ, MacFadyen JG, Nordestgaard BG, Shepherd J, Willerson JT, Glynn RJ; JUPITER Study Group.

N Engl J Med. 2008 Nov 20;359(21):2195-207. Epub 2008 Nov 9.PMID: 18997196 [PubMed - indexed for MEDLINE]Related articlesFree article

Ethical issues and global health.

Fins JJ, Fein OT, Gotto AM Jr.

Acad Med. 2008 Nov;83(11):997. No abstract available. PMID: 18971647 [PubMed - indexed for MEDLINE]Related articles

Activation of peroxisome proliferator-activated receptor-alpha in mice induces expression of the hepatic low-density lipoprotein receptor.

Huang Z, Zhou X, Nicholson AC, Gotto AM Jr, Hajjar DP, Han J.

Br J Pharmacol. 2008 Oct;155(4):596-605. Epub 2008 Aug 18.PMID: 18852694 [PubMed - indexed for MEDLINE]Related articlesFree article

Baseline characteristics of participants in the JUPITER trial, a randomized placebo-controlled primary prevention trial of statin therapy among individuals with low low-density lipoprotein cholesterol and elevated high-sensitivity C-reactive protein.

Ridker PM, Fonseca FA, Genest J, Gotto AM, Kastelein JJ, Khurmi NS, Koenig W, Libby P, Lorenzatti AJ, Nordestgaard BG, Shepherd J, Willerson JT, Glynn RJ; JUPITER Trial Study Group.

Am J Cardiol. 2007 Dec 1;100(11):1659-64. Epub 2007 Oct 24.PMID: 18036365 [PubMed - indexed for MEDLINE]Related articles

Genetic deletion of low density lipoprotein receptor impairs sterol-induced mouse macrophage ABCA1 expression. A new SREBP1-dependent mechanism.

Zhou X, He W, Huang Z, Gotto AM Jr, Hajjar DP, Han J.

J Biol Chem. 2008 Jan 25;283(4):2129-38. Epub 2007 Nov 20.PMID: 18029360 [PubMed - indexed for MEDLINE]Related articlesFree article

HDL cholesterol, very low levels of LDL cholesterol, and cardiovascular events.

Barter P, Gotto AM, LaRosa JC, Maroni J, Szarek M, Grundy SM, Kastelein JJ, Bittner V, Fruchart JC; Treating to New Targets Investigators.

N Engl J Med. 2007 Sep 27;357(13):1301-10.PMID: 17898099 [PubMed - indexed for MEDLINE]Related articlesFree article

Treatment of HIV-associated dyslipidemia: a role for omega-3 fatty acids.

Metroka CE, Truong P, Gotto AM Jr.

AIDS Read. 2007 Jul;17(7):362-4, 367-73. Review.PMID: 17672015 [PubMed - indexed for MEDLINE]Related articles

Does torcetrapib reduce the progression of atherosclerotic disease?

Gotto AM Jr.

Nat Clin Pract Cardiovasc Med. 2007 Sep;4(9):478-9. Epub 2007 Jul 10. No abstract available. PMID: 17622223 [PubMed]Related articles

A trilogy of primary prevention statin trials. Panel discussion.

Matsuzawa Y, Kita T, Shepherd J, Gotto AM Jr, Nakamura H, Sacks FM, Oikawa S, Sasaki J.

Atheroscler Suppl. 2007 Aug;8(2):19-24. Epub 2007 Jun 27.PMID: 17588827 [PubMed - indexed for MEDLINE]Related articles

Establishing the benefit of statins in low-to-moderate--risk primary prevention: the Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS).

Gotto AM Jr.

Atheroscler Suppl. 2007 Aug;8(2):3-8. Epub 2007 Jun 27.PMID: 17588826 [PubMed - indexed for MEDLINE]Related articles

Anti-adipogenic action of pitavastatin occurs through the coordinate regulation of PPARgamma and Pref-1 expression.

Nicholson AC, Hajjar DP, Zhou X, He W, Gotto AM Jr, Han J.

Br J Pharmacol. 2007 Jul;151(6):807-15. Epub 2007 Jun 4.PMID: 17549051 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of C-reactive protein in coronary risk reduction: focus on primary prevention.

Gotto AM Jr.

Am J Cardiol. 2007 Mar 1;99(5):718-25. Epub 2007 Jan 10. Review. Erratum in: Am J Cardiol. 2007 Aug 15;100(4):746. PMID: 17317380 [PubMed - indexed for MEDLINE]Related articles

Cardiologist's role in improving glucose control and global cardiovascular risk in patients with type 2 diabetes mellitus.

Gotto AM Jr.

Am J Cardiol. 2007 Feb 19;99(4A):3B-5B. Epub 2006 Dec 20. Review.PMID: 17307053 [PubMed - indexed for MEDLINE]Related articles

Statin therapy and the elderly: SAGE advice?

Gotto AM Jr.

Circulation. 2007 Feb 13;115(6):681-3. No abstract available. PMID: 17296867 [PubMed - indexed for MEDLINE]Related articlesFree article

The Editor's Roundtable: the metabolic syndrome.

Friedewald VE, Grundy S, Gotto AM Jr, Haffner S, Denke MA, Hollander P, Roberts WC.

Am J Cardiol. 2007 Feb 1;99(3):382-9. Epub 2006 Dec 8. No abstract available. PMID: 17261403 [PubMed - indexed for MEDLINE]Related articles

Drug insight: the role of statins in combination with ezetimibe to lower LDL cholesterol.

Gotto AM Jr, Farmer JA.

Nat Clin Pract Cardiovasc Med. 2006 Dec;3(12):664-72. Review.PMID: 17122799 [PubMed - indexed for MEDLINE]Related articles

Effects of high-dose atorvastatin on cerebrovascular events in patients with stable coronary disease in the TNT (treating to new targets) study.

Waters DD, LaRosa JC, Barter P, Fruchart JC, Gotto AM Jr, Carter R, Breazna A, Kastelein JJ, Grundy SM.

J Am Coll Cardiol. 2006 Nov 7;48(9):1793-9. Epub 2006 Oct 17.PMID: 17084252 [PubMed - indexed for MEDLINE]Related articles

Is it appropriate to make statins available over the counter? Over-the-counter statins are worth considering in primary prevention of cardiovascular disease.

Gotto AM Jr.

Circulation. 2006 Sep 19;114(12):1310-4; discussion 1314. No abstract available. PMID: 16982952 [PubMed - indexed for MEDLINE]Related articlesFree article

Statins, cardiovascular disease, and drug safety.

Gotto AM Jr.

Am J Cardiol. 2006 Apr 17;97(8A):3C-5C. Epub 2006 Jan 25. Review.PMID: 16581326 [PubMed - indexed for MEDLINE]Related articles

The benefits of statin therapy--what questions remain?

Gotto AM Jr, LaRosa JC.

Clin Cardiol. 2005 Nov;28(11):499-503. Review.PMID: 16450792 [PubMed - indexed for MEDLINE]Related articles

The metabolic syndrome: a call to action.

Gotto AM Jr, Blackburn GL, Dailey GE 3rd, Garber AJ, Grundy SM, Sobel BE, Weir MR.

Coron Artery Dis. 2006 Feb;17(1):77-80. Review.PMID: 16374146 [PubMed - indexed for MEDLINE]Related articles

Implications from the Air Force/Texas Coronary Atherosclerosis Prevention Study for the Adult Treatment Panel III guidelines.

Clearfield M, Downs JR, Lee M, Langendorfer A, McConathy W, Gotto AM Jr.

Am J Cardiol. 2005 Dec 15;96(12):1674-80. Epub 2005 Nov 2.PMID: 16360356 [PubMed - indexed for MEDLINE]Related articles

Should patients with combined hyperlipidemia receive statin-fibrate combination therapy?

Gotto AM Jr.

Nat Clin Pract Cardiovasc Med. 2005 Jun;2(6):284-5. No abstract available. PMID: 16265530 [PubMed]Related articles

Building a transcontinental affiliation: a new model for academic health centers.

Sostman HD, Forese LL, Boom ML, Schroth L, Klein AA, Mushlin AI, Hagale JE, Pardes H, Girotto RG, Gotto AM Jr.

Acad Med. 2005 Nov;80(11):1046-53.PMID: 16249304 [PubMed - indexed for MEDLINE]Related articles

Evolving concepts of dyslipidemia, atherosclerosis, and cardiovascular disease: the Louis F. Bishop Lecture.

Gotto AM Jr.

J Am Coll Cardiol. 2005 Oct 4;46(7):1219-24. Review. No abstract available. PMID: 16198834 [PubMed - indexed for MEDLINE]Related articles

Over-the-counter statins and cardiovascular disease prevention: perspectives, challenges, and opportunities.

Gotto AM Jr.

Clin Pharmacol Ther. 2005 Sep;78(3):213-7. No abstract available. PMID: 16153391 [PubMed - indexed for MEDLINE]Related articles

Review of primary and secondary prevention trials with lovastatin, pravastatin, and simvastatin.

Gotto AM Jr.

Am J Cardiol. 2005 Sep 5;96(5A):34F-38F. Review.PMID: 16126021 [PubMed - indexed for MEDLINE]Related articles

A common PCSK9 haplotype, encompassing the E670G coding single nucleotide polymorphism, is a novel genetic marker for plasma low-density lipoprotein cholesterol levels and severity of coronary atherosclerosis.

Chen SN, Ballantyne CM, Gotto AM Jr, Tan Y, Willerson JT, Marian AJ.

J Am Coll Cardiol. 2005 May 17;45(10):1611-9. Epub 2005 Apr 21.PMID: 15893176 [PubMed - indexed for MEDLINE]Related articles

Intensive lipid lowering with atorvastatin in patients with stable coronary disease.

LaRosa JC, Grundy SM, Waters DD, Shear C, Barter P, Fruchart JC, Gotto AM, Greten H, Kastelein JJ, Shepherd J, Wenger NK; Treating to New Targets (TNT) Investigators.

N Engl J Med. 2005 Apr 7;352(14):1425-35. Epub 2005 Mar 8.PMID: 15755765 [PubMed - indexed for MEDLINE]Related articlesFree article

A randomized trial of a strategy for increasing high-density lipoprotein cholesterol levels: effects on progression of coronary heart disease and clinical events.

Whitney EJ, Krasuski RA, Personius BE, Michalek JE, Maranian AM, Kolasa MW, Monick E, Brown BG, Gotto AM Jr.

Ann Intern Med. 2005 Jan 18;142(2):95-104.PMID: 15657157 [PubMed - indexed for MEDLINE]Related articlesFree article

Efficacy and safety of statin therapy in children with familial hypercholesterolemia: a randomized controlled trial.

Gotto AM.

J Pediatr. 2005 Jan;146(1):144-5. No abstract available. PMID: 15644844 [PubMed]Related articles

Functional interplay between the macrophage scavenger receptor class B type I and pitavastatin (NK-104).

Han J, Parsons M, Zhou X, Nicholson AC, Gotto AM Jr, Hajjar DP.

Circulation. 2004 Nov 30;110(22):3472-9. Epub 2004 Nov 22.PMID: 15557368 [PubMed - indexed for MEDLINE]Related articlesFree article

The case for over-the-counter statins.

Gotto AM Jr.

Am J Cardiol. 2004 Sep 15;94(6):753-6. Review. No abstract available. PMID: 15374779 [PubMed - indexed for MEDLINE]Related articles

Update on statins: 2003.

Vaughan CJ, Gotto AM Jr.

Circulation. 2004 Aug 17;110(7):886-92. Review. No abstract available. PMID: 15313959 [PubMed - indexed for MEDLINE]Related articlesFree article

Intensive versus moderate lipid lowering with statins after acute coronary syndromes.

Gotto AM Jr.

N Engl J Med. 2004 Aug 12;351(7):714-7; author reply 714-7. No abstract available. PMID: 15309745 [PubMed - indexed for MEDLINE]Related articles

Targeting high-risk young patients for statin therapy.

Gotto AM Jr.

JAMA. 2004 Jul 21;292(3):377-8. No abstract available. PMID: 15265854 [PubMed - indexed for MEDLINE]Related articles

C-reactive protein and coronary heart disease.

Foody JM, Gotto AM, Wenger N.

N Engl J Med. 2004 Jul 15;351(3):295-8; author reply 295-8. No abstract available. PMID: 15257565 [PubMed - indexed for MEDLINE]Related articles

Inflammation in atherosclerosis and implications for therapy.

Paoletti R, Gotto AM Jr, Hajjar DP.

Circulation. 2004 Jun 15;109(23 Suppl 1):III20-6. Review.PMID: 15198962 [PubMed - indexed for MEDLINE]Related articlesFree article

HDL cholesterol and protective factors in atherosclerosis.

Assmann G, Gotto AM Jr.

Circulation. 2004 Jun 15;109(23 Suppl 1):III8-14. Review.PMID: 15198960 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of PPARalpha, gamma and delta haplotypes on plasma levels of lipids, severity and progression of coronary atherosclerosis and response to statin therapy in the lipoprotein coronary atherosclerosis study.

Chen S, Tsybouleva N, Ballantyne CM, Gotto AM Jr, Marian AJ.

Pharmacogenetics. 2004 Jan;14(1):61-71.PMID: 15128052 [PubMed - indexed for MEDLINE]Related articles