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    Results: 29

    1.

    Improved insulin sensitivity and islet function after PPARdelta activation in diabetic db/db mice.

    Winzell MS, Wulff EM, Olsen GS, Sauerberg P, Gotfredsen CF, Ahrén B.

    Eur J Pharmacol. 2009 Oct 8. [Epub ahead of print]PMID: 19818749 [PubMed - as supplied by publisher]Related articles

    2.

    Synergistic effect of the human GLP-1 analogue liraglutide and a dual PPARalpha/gamma agonist on glycaemic control in Zucker diabetic fatty rats.

    Brand CL, Galsgaard ED, Tornehave D, Rømer J, Gotfredsen CF, Wassermann K, Knudsen LB, Vølund A, Sturis J.

    Diabetes Obes Metab. 2009 Aug;11(8):795-803. Epub 2009 Jun 10.PMID: 19519868 [PubMed - in process]Related articles

    3.

    Combination of the insulin sensitizer, pioglitazone, and the long-acting GLP-1 human analog, liraglutide, exerts potent synergistic glucose-lowering efficacy in severely diabetic ZDF rats.

    Larsen PJ, Wulff EM, Gotfredsen CF, Brand CL, Sturis J, Vrang N, Knudsen LB, Lykkegaard K.

    Diabetes Obes Metab. 2008 Apr;10(4):301-11.PMID: 18333889 [PubMed - indexed for MEDLINE]Related articles

    4.

    Evaluation of beta-cell mass and function in the Göttingen minipig.

    Larsen MO, Rolin B, Raun K, Bjerre Knudsen L, Gotfredsen CF, Bock T.

    Diabetes Obes Metab. 2007 Nov;9 Suppl 2:170-9.PMID: 17919191 [PubMed - indexed for MEDLINE]Related articles

    5.

    Liraglutide, a long-acting glucagon-like peptide-1 analog, reduces body weight and food intake in obese candy-fed rats, whereas a dipeptidyl peptidase-IV inhibitor, vildagliptin, does not.

    Raun K, von Voss P, Gotfredsen CF, Golozoubova V, Rolin B, Knudsen LB.

    Diabetes. 2007 Jan;56(1):8-15.PMID: 17192459 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Measurements of insulin responses as predictive markers of pancreatic beta-cell mass in normal and beta-cell-reduced lean and obese Göttingen minipigs in vivo.

    Larsen MO, Rolin B, Sturis J, Wilken M, Carr RD, Pørksen N, Gotfredsen CF.

    Am J Physiol Endocrinol Metab. 2006 Apr;290(4):E670-7. Epub 2005 Nov 8.PMID: 16278249 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Long-term AICAR administration and exercise prevents diabetes in ZDF rats.

    Pold R, Jensen LS, Jessen N, Buhl ES, Schmitz O, Flyvbjerg A, Fujii N, Goodyear LJ, Gotfredsen CF, Brand CL, Lund S.

    Diabetes. 2005 Apr;54(4):928-34.PMID: 15793229 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Reduction of beta cell mass: partial insulin secretory compensation from the residual beta cell population in the nicotinamide-streptozotocin Göttingen minipig after oral glucose in vivo and in the perfused pancreas.

    Larsen MO, Rolin B, Gotfredsen CF, Carr RD, Holst JJ.

    Diabetologia. 2004 Nov;47(11):1873-8. Epub 2004 Nov 24.PMID: 15565374 [PubMed - indexed for MEDLINE]Related articles

    9.

    Beta-cell function and islet morphology in normal, obese, and obese beta-cell mass-reduced Göttingen minipigs.

    Larsen MO, Juhl CB, Pørksen N, Gotfredsen CF, Carr RD, Ribel U, Wilken M, Rolin B.

    Am J Physiol Endocrinol Metab. 2005 Feb;288(2):E412-21. Epub 2004 Oct 12.PMID: 15479954 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Changes in expression of IL-1 beta influenced proteins in transplanted islets during development of diabetes in diabetes-prone BB rats.

    Sparre T, Christensen UB, Gotfredsen CF, Larsen PM, Fey SJ, Hjernø K, Roepstorff P, Pociot F, Karlsen AE, Nerup J.

    Diabetologia. 2004 May;47(5):892-908. Epub 2004 Apr 23.PMID: 15105991 [PubMed - indexed for MEDLINE]Related articles

    11.

    Improved beta-cell survival and reduced insulitis in a type 1 diabetic rat model after treatment with a beta-cell-selective K(ATP) channel opener.

    Skak K, Gotfredsen CF, Lundsgaard D, Hansen JB, Sturis J, Markholst H.

    Diabetes. 2004 Apr;53(4):1089-95.PMID: 15047626 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Valine pyrrolidide preserves intact glucose-dependent insulinotropic peptide and improves abnormal glucose tolerance in minipigs with reduced beta-cell mass.

    Larsen MO, Rolin B, Ribel U, Wilken M, Deacon CF, Svendsen O, Gotfredsen CF, Carr RD.

    Exp Diabesity Res. 2003 Apr-Jun;4(2):93-105.PMID: 14630571 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    GLP-1 derivative liraglutide in rats with beta-cell deficiencies: influence of metabolic state on beta-cell mass dynamics.

    Sturis J, Gotfredsen CF, Rømer J, Rolin B, Ribel U, Brand CL, Wilken M, Wassermann K, Deacon CF, Carr RD, Knudsen LB.

    Br J Pharmacol. 2003 Sep;140(1):123-32. Epub 2003 Jul 29.PMID: 12967942 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Loss of beta-cell mass leads to a reduction of pulse mass with normal periodicity, regularity and entrainment of pulsatile insulin secretion in Göttingen minipigs.

    Larsen MO, Gotfredsen CF, Wilken M, Carr RD, Pørksen N, Rolin B.

    Diabetologia. 2003 Feb;46(2):195-202. Epub 2003 Jan 11. Erratum in: Diabetologia. 2004 Jan;47(1):155. PMID: 12627318 [PubMed - indexed for MEDLINE]Related articles

    15.

    Measurements of insulin secretory capacity and glucose tolerance to predict pancreatic beta-cell mass in vivo in the nicotinamide/streptozotocin Göttingen minipig, a model of moderate insulin deficiency and diabetes.

    Larsen MO, Rolin B, Wilken M, Carr RD, Gotfredsen CF.

    Diabetes. 2003 Jan;52(1):118-23.PMID: 12502501 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Dual PPARalpha /gamma activation provides enhanced improvement of insulin sensitivity and glycemic control in ZDF rats.

    Brand CL, Sturis J, Gotfredsen CF, Fleckner J, Fledelius C, Hansen BF, Andersen B, Ye JM, Sauerberg P, Wassermann K.

    Am J Physiol Endocrinol Metab. 2003 Apr;284(4):E841-54. Epub 2002 Dec 10.PMID: 12475752 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    The long-acting GLP-1 derivative NN2211 ameliorates glycemia and increases beta-cell mass in diabetic mice.

    Rolin B, Larsen MO, Gotfredsen CF, Deacon CF, Carr RD, Wilken M, Knudsen LB.

    Am J Physiol Endocrinol Metab. 2002 Oct;283(4):E745-52.PMID: 12217892 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Nateglinide, but not repaglinide, stimulates growth hormone release in rat pituitary cells by inhibition of K channels and stimulation of cyclic AMP-dependent exocytosis.

    Gromada J, Bokvist K, Høy M, Olsen HL, Lindström P, Hansen BS, Gotfredsen CF, Rorsman P, Thomsen MK.

    Eur J Endocrinol. 2002 Jul;147(1):133-42.PMID: 12088930 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Mild streptozotocin diabetes in the Göttingen minipig. A novel model of moderate insulin deficiency and diabetes.

    Larsen MO, Wilken M, Gotfredsen CF, Carr RD, Svendsen O, Rolin B.

    Am J Physiol Endocrinol Metab. 2002 Jun;282(6):E1342-51.PMID: 12006365 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Gi2 proteins couple somatostatin receptors to low-conductance K+ channels in rat pancreatic alpha-cells.

    Gromada J, Høy M, Olsen HL, Gotfredsen CF, Buschard K, Rorsman P, Bokvist K.

    Pflugers Arch. 2001 Apr;442(1):19-26.PMID: 11374064 [PubMed - indexed for MEDLINE]Related articles

    21.

    Characterisation of sulphonylurea and ATP-regulated K+ channels in rat pancreatic A-cells.

    Bokvist K, Olsen HL, Høy M, Gotfredsen CF, Holmes WF, Buschard K, Rorsman P, Gromada J.

    Pflugers Arch. 1999 Sep;438(4):428-36.PMID: 10519134 [PubMed - indexed for MEDLINE]Related articles

    22.

    Fetal rat pancreas transplantation in BB rats: immunohistochemical and functional evaluation.

    Yderstraede KB, Starklint H, Steinbruchel D, Jørgensen TW, Gotfredsen CF.

    Virchows Arch B Cell Pathol Incl Mol Pathol. 1993;64(1):13-9.PMID: 8401812 [PubMed - indexed for MEDLINE]Related articles

    23.

    The fate of transplanted encapsulated islets in spontaneously diabetic BB/Wor rats.

    Gotfredsen CF, Stewart MG, O'Shea GM, Vose JR, Horn T, Moody AJ.

    Diabetes Res. 1990 Dec;15(4):157-63.PMID: 2132404 [PubMed - indexed for MEDLINE]Related articles

    24.

    Immunological and insulin secretory studies on isolated porcine islets of Langerhans.

    Crowther NJ, Gotfredsen CF, Moody AJ, Green IC.

    J Endocrinol. 1990 Jul;126(1):43-9.PMID: 1696304 [PubMed - indexed for MEDLINE]Related articles

    25.

    Porcine islet isolation, cellular composition and secretory response.

    Crowther NJ, Gotfredsen CF, Moody AJ, Green IC.

    Horm Metab Res. 1989 Nov;21(11):590-5.PMID: 2480322 [PubMed - indexed for MEDLINE]Related articles

    26.

    Reduction of diabetes incidence of BB Wistar rats by early prophylactic insulin treatment of diabetes-prone animals.

    Gotfredsen CF, Buschard K, Frandsen EK.

    Diabetologia. 1985 Dec;28(12):933-5.PMID: 4092862 [PubMed - indexed for MEDLINE]Related articles

    27.

    Cellular localization of stable solid liposomes in the liver of rats.

    Gotfredsen CF, Van Berkel TJ, Kruijt JK, Goethals A.

    Biochem Pharmacol. 1983 Nov 15;32(22):3389-96.PMID: 6651863 [PubMed - indexed for MEDLINE]Related articles

    28.

    Disposition of intact liposomes of different compositions and of liposomal degradation products.

    Gotfredsen CF, Frøkjaer S, Hjorth EL, Jørgensen KD, Debroux-Guisset MC.

    Biochem Pharmacol. 1983 Nov 15;32(22):3381-7.PMID: 6651862 [PubMed - indexed for MEDLINE]Related articles

    29.

    Dynamics of sulfonylurea-induced insulin release from the isolated perfused rat pancreas.

    Gotfredsen CF.

    Diabetologia. 1976 Aug;12(4):339-42.PMID: 134920 [PubMed - indexed for MEDLINE]Related articles

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