PubMed

Developments in the scientific understanding of rheumatoid arthritis.

Goronzy JJ, Weyand CM.

Arthritis Res Ther. 2009 Oct 14;11(5):249. [Epub ahead of print]PMID: 19835638 [PubMed - as supplied by publisher]Related articles

Rejuvenating the immune system in rheumatoid arthritis.

Weyand CM, Fujii H, Shao L, Goronzy JJ.

Nat Rev Rheumatol. 2009 Oct;5(10):583-8.PMID: 19798035 [PubMed - in process]Related articles

Vascular damage in giant cell arteritis.

Piggott K, Biousse V, Newman NJ, Goronzy JJ, Weyand CM.

Autoimmunity. 2009 Nov;42(7):596-604.PMID: 19657775 [PubMed - in process]Related articles

Epigenetic regulation of killer immunoglobulin-like receptor expression in T cells.

Li G, Yu M, Weyand CM, Goronzy JJ.

Blood. 2009 Oct 15;114(16):3422-30. Epub 2009 Jul 23.PMID: 19628706 [PubMed - indexed for MEDLINE]Related articles

Treating autoimmune disease by targeting CD8(+) T suppressor cells.

Konya C, Goronzy JJ, Weyand CM.

Expert Opin Biol Ther. 2009 Aug;9(8):951-65. Review.PMID: 19522557 [PubMed - indexed for MEDLINE]Related articles

Deficiency of the DNA repair enzyme ATM in rheumatoid arthritis.

Shao L, Fujii H, Colmegna I, Oishi H, Goronzy JJ, Weyand CM.

J Exp Med. 2009 Jun 8;206(6):1435-49. Epub 2009 May 18.PMID: 19451263 [PubMed - indexed for MEDLINE]Related articles

Altered naive and memory CD4+ T-cell homeostasis and immunosenescence characterize younger patients with myelodysplastic syndrome.

Zou JX, Rollison DE, Boulware D, Chen DT, Sloand EM, Pfannes LV, Goronzy JJ, Bai F, Painter JS, Wei S, Cosgrove D, List AF, Epling-Burnette PK.

Leukemia. 2009 Jul;23(7):1288-96. Epub 2009 Mar 12.PMID: 19282834 [PubMed - indexed for MEDLINE]Related articles

Telomerase insufficiency in rheumatoid arthritis.

Fujii H, Shao L, Colmegna I, Goronzy JJ, Weyand CM.

Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4360-5. Epub 2009 Mar 2.PMID: 19255426 [PubMed - indexed for MEDLINE]Related articlesFree article

[Pathogenesis of medium- and large-vessel vasculitis]

Weyand CM, Goronzy JJ.

Z Rheumatol. 2009 Mar;68(2):100-7. Review. German. PMID: 19224227 [PubMed - indexed for MEDLINE]Related articles

Toll-like receptors 4 and 5 induce distinct types of vasculitis.

Deng J, Ma-Krupa W, Gewirtz AT, Younge BR, Goronzy JJ, Weyand CM.

Circ Res. 2009 Feb 27;104(4):488-95. Epub 2009 Jan 15.PMID: 19150884 [PubMed - indexed for MEDLINE]Related articles

Age-dependent signature of metallothionein expression in primary CD4 T cell responses is due to sustained zinc signaling.

Lee WW, Cui D, Czesnikiewicz-Guzik M, Vencio RZ, Shmulevich I, Aderem A, Weyand CM, Goronzy JJ.

Rejuvenation Res. 2008 Dec;11(6):1001-11.PMID: 19072254 [PubMed - indexed for MEDLINE]Related articles

T-cell co-stimulatory pathways in autoimmunity.

Goronzy JJ, Weyand CM.

Arthritis Res Ther. 2008;10 Suppl 1:S3. Epub 2008 Oct 15. Review.PMID: 19007423 [PubMed - indexed for MEDLINE]Related articlesFree article

T cells in arteritis and atherosclerosis.

Weyand CM, Younge BR, Goronzy JJ.

Curr Opin Lipidol. 2008 Oct;19(5):469-77. Review.PMID: 18841594 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibitory CD8+ T cells in autoimmune disease.

Suzuki M, Konya C, Goronzy JJ, Weyand CM.

Hum Immunol. 2008 Nov;69(11):781-9. Epub 2008 Sep 21. Review.PMID: 18812196 [PubMed - indexed for MEDLINE]Related articlesFree article

Vessel-specific Toll-like receptor profiles in human medium and large arteries.

Pryshchep O, Ma-Krupa W, Younge BR, Goronzy JJ, Weyand CM.

Circulation. 2008 Sep 16;118(12):1276-84. Epub 2008 Sep 2.PMID: 18765390 [PubMed - indexed for MEDLINE]Related articlesFree article

Epigenetic mechanisms of age-dependent KIR2DL4 expression in T cells.

Li G, Weyand CM, Goronzy JJ.

J Leukoc Biol. 2008 Sep;84(3):824-34. Epub 2008 Jun 27.PMID: 18586981 [PubMed - indexed for MEDLINE]Related articlesFree article

Occurrence of giant cell arteritis...suddenly.

Younge BR, Weyand CM, Goronzy JJ.

Trans Am Ophthalmol Soc. 2007;105:141-4; discussion 144-5.PMID: 18427603 [PubMed - indexed for MEDLINE]Related articlesFree article

Defective proliferative capacity and accelerated telomeric loss of hematopoietic progenitor cells in rheumatoid arthritis.

Colmegna I, Diaz-Borjon A, Fujii H, Schaefer L, Goronzy JJ, Weyand CM.

Arthritis Rheum. 2008 Apr;58(4):990-1000.PMID: 18383391 [PubMed - indexed for MEDLINE]Related articlesFree article

TLR-mediated induction of negative regulatory ligands on dendritic cells.

Gröschel S, Piggott KD, Vaglio A, Ma-Krupa W, Singh K, Goronzy JJ, Weyand CM.

J Mol Med. 2008 Apr;86(4):443-55. Epub 2008 Feb 6.PMID: 18253710 [PubMed - indexed for MEDLINE]Related articlesFree article

T cell subset-specific susceptibility to aging.

Czesnikiewicz-Guzik M, Lee WW, Cui D, Hiruma Y, Lamar DL, Yang ZZ, Ouslander JG, Weyand CM, Goronzy JJ.

Clin Immunol. 2008 Apr;127(1):107-18. Epub 2008 Jan 28.PMID: 18222733 [PubMed - indexed for MEDLINE]Related articlesFree article

Immune-mediated mechanisms in atherosclerosis: prevention and treatment of clinical manifestations.

Niessner A, Goronzy JJ, Weyand CM.

Curr Pharm Des. 2007;13(36):3701-10. Review.PMID: 18220809 [PubMed - indexed for MEDLINE]Related articles

Synoviocyte stimulation by the LFA-1-intercellular adhesion molecule-2-Ezrin-Akt pathway in rheumatoid arthritis.

Singh K, Colmegna I, He X, Weyand CM, Goronzy JJ.

J Immunol. 2008 Feb 1;180(3):1971-8.PMID: 18209096 [PubMed - indexed for MEDLINE]Related articlesFree article

Vessel wall-embedded dendritic cells induce T-cell autoreactivity and initiate vascular inflammation.

Han JW, Shimada K, Ma-Krupa W, Johnson TL, Nerem RM, Goronzy JJ, Weyand CM.

Circ Res. 2008 Mar 14;102(5):546-53. Epub 2008 Jan 17.PMID: 18202318 [PubMed - indexed for MEDLINE]Related articlesFree article

Synergistic proinflammatory effects of the antiviral cytokine interferon-alpha and Toll-like receptor 4 ligands in the atherosclerotic plaque.

Niessner A, Shin MS, Pryshchep O, Goronzy JJ, Chaikof EL, Weyand CM.

Circulation. 2007 Oct 30;116(18):2043-52. Epub 2007 Oct 15.PMID: 17938289 [PubMed - indexed for MEDLINE]Related articlesFree article

Fractalkine mediates T cell-dependent proliferation of synovial fibroblasts in rheumatoid arthritis.

Sawai H, Park YW, He X, Goronzy JJ, Weyand CM.

Arthritis Rheum. 2007 Oct;56(10):3215-25.PMID: 17907166 [PubMed - indexed for MEDLINE]Related articlesFree article

Unchecked CD70 expression on T cells lowers threshold for T cell activation in rheumatoid arthritis.

Lee WW, Yang ZZ, Li G, Weyand CM, Goronzy JJ.

J Immunol. 2007 Aug 15;179(4):2609-15.PMID: 17675524 [PubMed - indexed for MEDLINE]Related articlesFree article

Aging and T-cell diversity.

Goronzy JJ, Lee WW, Weyand CM.

Exp Gerontol. 2007 May;42(5):400-6. Epub 2007 Jan 10. Review.PMID: 17218073 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional profile of activated dendritic cells in unstable atherosclerotic plaque.

Erbel C, Sato K, Meyer FB, Kopecky SL, Frye RL, Goronzy JJ, Weyand CM.

Basic Res Cardiol. 2007 Mar;102(2):123-32. Epub 2006 Dec 1.PMID: 17136419 [PubMed - indexed for MEDLINE]Related articles

Treatment of chronic inflammatory diseases with biologic agents: opportunities and risks for the elderly.

Diaz-Borjon A, Weyand CM, Goronzy JJ.

Exp Gerontol. 2006 Dec;41(12):1250-5. Epub 2006 Nov 27. Review.PMID: 17125948 [PubMed - indexed for MEDLINE]Related articlesFree article

Pathogen-sensing plasmacytoid dendritic cells stimulate cytotoxic T-cell function in the atherosclerotic plaque through interferon-alpha.

Niessner A, Sato K, Chaikof EL, Colmegna I, Goronzy JJ, Weyand CM.

Circulation. 2006 Dec 5;114(23):2482-9. Epub 2006 Nov 20.PMID: 17116765 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunosuppression in atherosclerosis: mobilizing the opposition within.

Goronzy JJ, Weyand CM.

Circulation. 2006 Oct 31;114(18):1901-4. No abstract available. PMID: 17075023 [PubMed - indexed for MEDLINE]Related articlesFree article

HLA-DRB1 haplotype did not affect the medium-term results of total knee arthroplasty in patients with rheumatoid arthritis.

Takemura S, Toda Y, Goronzy JJ, Weyand CM, Ogawa R, Iida H.

Mod Rheumatol. 2004;14(1):37-42.PMID: 17028803 [PubMed - in process]Related articles

Treatment of giant cell arteritis using induction therapy with high-dose glucocorticoids: a double-blind, placebo-controlled, randomized prospective clinical trial.

Mazlumzadeh M, Hunder GG, Easley KA, Calamia KT, Matteson EL, Griffing WL, Younge BR, Weyand CM, Goronzy JJ.

Arthritis Rheum. 2006 Oct;54(10):3310-8.PMID: 17009270 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of HLA-C3 and smoking with vasculitis in patients with rheumatoid arthritis.

Turesson C, Schaid DJ, Weyand CM, Jacobsson LT, Goronzy JJ, Petersson IF, Dechant SA, Nyähll-Wåhlin BM, Truedsson L, Sturfelt G, Matteson EL.

Arthritis Rheum. 2006 Sep;54(9):2776-83.PMID: 16947780 [PubMed - indexed for MEDLINE]Related articlesFree article

T-cell-targeted therapies in rheumatoid arthritis.

Weyand CM, Goronzy JJ.

Nat Clin Pract Rheumatol. 2006 Apr;2(4):201-10. Review.PMID: 16932686 [PubMed - indexed for MEDLINE]Related articles

T cell recognition and killing of vascular smooth muscle cells in acute coronary syndrome.

Pryshchep S, Sato K, Goronzy JJ, Weyand CM.

Circ Res. 2006 May 12;98(9):1168-76. Epub 2006 Apr 6.PMID: 16601227 [PubMed - indexed for MEDLINE]Related articlesFree article

Pathomechanisms in rheumatoid arthritis--time for a string theory?

Weyand CM, Goronzy JJ.

J Clin Invest. 2006 Apr;116(4):869-71.PMID: 16585957 [PubMed - indexed for MEDLINE]Related articlesFree article

Lymphoma in rheumatoid arthritis: an immune system set up for failure.

Weyand CM, Goronzy JJ, Kurtin PJ.

Arthritis Rheum. 2006 Mar;54(3):685-9. Review. No abstract available. PMID: 16508924 [PubMed - indexed for MEDLINE]Related articlesFree article

Uncoupling of T-cell effector functions by inhibitory killer immunoglobulin-like receptors.

Henel G, Singh K, Cui D, Pryshchep S, Lee WW, Weyand CM, Goronzy JJ.

Blood. 2006 Jun 1;107(11):4449-57. Epub 2006 Feb 9.PMID: 16469873 [PubMed - indexed for MEDLINE]Related articlesFree article

Vascular dendritic cells in giant cell arteritis.

Weyand CM, Ma-Krupa W, Pryshchep O, Gröschel S, Bernardino R, Goronzy JJ.

Ann N Y Acad Sci. 2005 Dec;1062:195-208. Review.PMID: 16461802 [PubMed - indexed for MEDLINE]Related articles

Costimulatory pathways in rheumatoid synovitis and T-cell senescence.

Goronzy JJ, Henel G, Sawai H, Singh K, Lee EB, Pryshchep S, Weyand CM.

Ann N Y Acad Sci. 2005 Dec;1062:182-94. Review.PMID: 16461801 [PubMed - indexed for MEDLINE]Related articles

Simvastatin suppresses endotoxin-induced upregulation of toll-like receptors 4 and 2 in vivo.

Niessner A, Steiner S, Speidl WS, Pleiner J, Seidinger D, Maurer G, Goronzy JJ, Weyand CM, Kopp CW, Huber K, Wolzt M, Wojta J.

Atherosclerosis. 2006 Dec;189(2):408-13. Epub 2006 Jan 26.PMID: 16443229 [PubMed - indexed for MEDLINE]Related articles

Telomeres, immune aging and autoimmunity.

Goronzy JJ, Fujii H, Weyand CM.

Exp Gerontol. 2006 Mar;41(3):246-51. Epub 2006 Jan 19. Review.PMID: 16427234 [PubMed - indexed for MEDLINE]Related articles

Interleukin 12 induces T-cell recruitment into the atherosclerotic plaque.

Zhang X, Niessner A, Nakajima T, Ma-Krupa W, Kopecky SL, Frye RL, Goronzy JJ, Weyand CM.

Circ Res. 2006 Mar 3;98(4):524-31. Epub 2006 Jan 19.PMID: 16424368 [PubMed - indexed for MEDLINE]Related articlesFree article

TRAIL-expressing T cells induce apoptosis of vascular smooth muscle cells in the atherosclerotic plaque.

Sato K, Niessner A, Kopecky SL, Frye RL, Goronzy JJ, Weyand CM.

J Exp Med. 2006 Jan 23;203(1):239-50. Epub 2006 Jan 17.PMID: 16418392 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue trafficking patterns of effector memory CD4+ T cells in rheumatoid arthritis.

Zhang X, Nakajima T, Goronzy JJ, Weyand CM.

Arthritis Rheum. 2005 Dec;52(12):3839-49.PMID: 16329093 [PubMed - indexed for MEDLINE]Related articlesFree article

The impact of HLA-DRB1 genes on extra-articular disease manifestations in rheumatoid arthritis.

Turesson C, Schaid DJ, Weyand CM, Jacobsson LT, Goronzy JJ, Petersson IF, Sturfelt G, Nyhäll-Wåhlin BM, Truedsson L, Dechant SA, Matteson EL.

Arthritis Res Ther. 2005;7(6):R1386-93. Epub 2005 Oct 11.PMID: 16277691 [PubMed - indexed for MEDLINE]Related articlesFree article

BLyS and APRIL in rheumatoid arthritis.

Seyler TM, Park YW, Takemura S, Bram RJ, Kurtin PJ, Goronzy JJ, Weyand CM.

J Clin Invest. 2005 Nov;115(11):3083-92. Epub 2005 Oct 20.PMID: 16239971 [PubMed - indexed for MEDLINE]Related articlesFree article

Rheumatoid arthritis is an independent risk factor for multi-vessel coronary artery disease: a case control study.

Warrington KJ, Kent PD, Frye RL, Lymp JF, Kopecky SL, Goronzy JJ, Weyand CM.

Arthritis Res Ther. 2005;7(5):R984-91. Epub 2005 Jun 29.PMID: 16207339 [PubMed - indexed for MEDLINE]Related articlesFree article

Modulation of CD28 expression with anti-tumor necrosis factor alpha therapy in rheumatoid arthritis.

Bryl E, Vallejo AN, Matteson EL, Witkowski JM, Weyand CM, Goronzy JJ.

Arthritis Rheum. 2005 Oct;52(10):2996-3003.PMID: 16200579 [PubMed - indexed for MEDLINE]Related articlesFree article