PubMed

The emerging role of SOX transcription factors in pancreatic endocrine cell development and function.

McDonald E, Krishnamurthy M, Goodyer CG, Wang R.

Stem Cells Dev. 2009 Sep 2. [Epub ahead of print]PMID: 19725755 [PubMed - as supplied by publisher]Related articles

Loss of anti-Bax function in gerstmann-Sträussler-Scheinker syndrome-associated prion protein mutants.

Jodoin J, Misiewicz M, Makhijani P, Giannopoulos PN, Hammond J, Goodyer CG, LeBlanc AC.

PLoS One. 2009 Aug 14;4(8):e6647.PMID: 19680558 [PubMed - in process]Related articlesFree article

beta1 integrin/FAK/ERK signalling pathway is essential for human fetal islet cell differentiation and survival.

Saleem S, Li J, Yee SP, Fellows GF, Goodyer CG, Wang R.

J Pathol. 2009 Oct;219(2):182-92.PMID: 19544355 [PubMed - in process]Related articles

Persistent organic pollutant residues in human fetal liver and placenta from Greater Montreal, Quebec: a longitudinal study from 1998 through 2006.

Doucet J, Tague B, Arnold DL, Cooke GM, Hayward S, Goodyer CG.

Environ Health Perspect. 2009 Apr;117(4):605-10. Epub 2008 Dec 10.PMID: 19440500 [PubMed - indexed for MEDLINE]Related articlesFree article

Structure and activity of the human growth hormone receptor (hGHR) gene V2 promoter.

Wei Y, Puzhko S, Wabitsch M, Goodyer CG.

Mol Endocrinol. 2009 Mar;23(3):360-72. Epub 2008 Dec 30.PMID: 19116246 [PubMed - indexed for MEDLINE]Related articles

Transcriptional regulation of the human growth hormone receptor (hGHR) gene V2 promoter by transcriptional activators and repressor.

Wei Y, Puzhko S, Wabitsch M, Goodyer CG.

Mol Endocrinol. 2009 Mar;23(3):373-87. Epub 2008 Dec 30.PMID: 19116245 [PubMed - indexed for MEDLINE]Related articles

Cytosolic prion protein is the predominant anti-Bax prion protein form: exclusion of transmembrane and secreted prion protein forms in the anti-Bax function.

Lin DT, Jodoin J, Baril M, Goodyer CG, Leblanc AC.

Biochim Biophys Acta. 2008 Oct;1783(10):2001-12. Epub 2008 Jun 6.PMID: 18590778 [PubMed - indexed for MEDLINE]Related articlesFree article

Transcription factor expression in the developing human fetal endocrine pancreas.

Lyttle BM, Li J, Krishnamurthy M, Fellows F, Wheeler MB, Goodyer CG, Wang R.

Diabetologia. 2008 Jul;51(7):1169-80. Epub 2008 May 20.PMID: 18491072 [PubMed - indexed for MEDLINE]Related articles

Developmental changes in the human GH receptor and its signal transduction pathways.

Kenth G, Mergelas JA, Goodyer CG.

J Endocrinol. 2008 Jul;198(1):71-82. Epub 2008 Apr 17.PMID: 18420710 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of the hepatic specific V1 messenger ribonucleic acid of the human growth hormone receptor gene is regulated by hepatic nuclear factor (HNF)-4alpha2 and HNF-4alpha8.

Goodyer CG, Rhani Z, Zheng H.

Mol Endocrinol. 2008 Feb;22(2):485-500. Epub 2007 Nov 8.PMID: 17991764 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of c-Kit receptor tyrosine kinase and effect on beta-cell development in the human fetal pancreas.

Li J, Quirt J, Do HQ, Lyte K, Fellows F, Goodyer CG, Wang R.

Am J Physiol Endocrinol Metab. 2007 Aug;293(2):E475-83. Epub 2007 May 22.PMID: 17519280 [PubMed - indexed for MEDLINE]Related articlesFree article

Defective retrotranslocation causes loss of anti-Bax function in human familial prion protein mutants.

Jodoin J, Laroche-Pierre S, Goodyer CG, LeBlanc AC.

J Neurosci. 2007 May 9;27(19):5081-91.PMID: 17494694 [PubMed - indexed for MEDLINE]Related articlesFree article

Mutations of the Wnt antagonist AXIN2 (Conductin) result in TCF-dependent transcription in medulloblastomas.

Koch A, Hrychyk A, Hartmann W, Waha A, Mikeska T, Waha A, Schüller U, Sörensen N, Berthold F, Goodyer CG, Wiestler OD, Birchmeier W, Behrens J, Pietsch T.

Int J Cancer. 2007 Jul 15;121(2):284-91.PMID: 17373666 [PubMed - indexed for MEDLINE]Related articles

SGNE1/7B2 is epigenetically altered and transcriptionally downregulated in human medulloblastomas.

Waha A, Koch A, Hartmann W, Milde U, Felsberg J, Hübner A, Mikeska T, Goodyer CG, Sörensen N, Lindberg I, Wiestler OD, Pietsch T, Waha A.

Oncogene. 2007 Aug 16;26(38):5662-8. Epub 2007 Mar 5.PMID: 17334394 [PubMed - indexed for MEDLINE]Related articles

Relationship of the human growth hormone receptor exon 3 genotype with final adult height and bone mineral density.

Kenth G, Shao Z, Cole DE, Goodyer CG.

J Clin Endocrinol Metab. 2007 Feb;92(2):725-8. Epub 2006 Nov 7.PMID: 17090634 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphatidylinositol 3'-kinase/AKT signaling is activated in medulloblastoma cell proliferation and is associated with reduced expression of PTEN.

Hartmann W, Digon-Söntgerath B, Koch A, Waha A, Endl E, Dani I, Denkhaus D, Goodyer CG, Sörensen N, Wiestler OD, Pietsch T.

Clin Cancer Res. 2006 May 15;12(10):3019-27.PMID: 16707597 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of growth hormone receptor messenger ribonucleic acid variants in human adipocytes.

Wei Y, Rhani Z, Goodyer CG.

J Clin Endocrinol Metab. 2006 May;91(5):1901-8. Epub 2006 Feb 21.PMID: 16492697 [PubMed - indexed for MEDLINE]Related articlesFree article

Stem cell factor/c-Kit interactions regulate human islet-epithelial cluster proliferation and differentiation.

Li J, Goodyer CG, Fellows F, Wang R.

Int J Biochem Cell Biol. 2006;38(5-6):961-72. Epub 2005 Sep 15.PMID: 16213778 [PubMed - indexed for MEDLINE]Related articles

Growth hormone during development.

Osafo J, Wei Y, Kenth G, Goodyer CG.

Rev Endocr Metab Disord. 2005 Aug;6(3):173-82. Review. No abstract available. PMID: 16151621 [PubMed - indexed for MEDLINE]Related articles

Caspase-1 activation of caspase-6 in human apoptotic neurons.

Guo H, Pétrin D, Zhang Y, Bergeron C, Goodyer CG, LeBlanc AC.

Cell Death Differ. 2006 Feb;13(2):285-92.PMID: 16123779 [PubMed - indexed for MEDLINE]Related articlesFree article

Role for beta1 integrin and its associated alpha3, alpha5, and alpha6 subunits in development of the human fetal pancreas.

Wang R, Li J, Lyte K, Yashpal NK, Fellows F, Goodyer CG.

Diabetes. 2005 Jul;54(7):2080-9.PMID: 15983209 [PubMed - indexed for MEDLINE]Related articlesFree article

Subtype-specific expression and genetic alterations of the chemokinereceptor gene CXCR4 in medulloblastomas.

Schüller U, Koch A, Hartmann W, Garrè ML, Goodyer CG, Cama A, Sörensen N, Wiestler OD, Pietsch T.

Int J Cancer. 2005 Oct 20;117(1):82-9.PMID: 15880586 [PubMed - indexed for MEDLINE]Related articles

Cellular prion protein inhibits proapoptotic Bax conformational change in human neurons and in breast carcinoma MCF-7 cells.

Roucou X, Giannopoulos PN, Zhang Y, Jodoin J, Goodyer CG, LeBlanc A.

Cell Death Differ. 2005 Jul;12(7):783-95.PMID: 15846375 [PubMed - indexed for MEDLINE]Related articlesFree article

No evidence for mutations or altered expression of the Suppressor of Fused gene (SUFU) in primitive neuroectodermal tumours.

Koch A, Waha A, Hartmann W, Milde U, Goodyer CG, Sörensen N, Berthold F, Digon-Söntgerath B, Krätzschmar J, Wiestler OD, Pietsch T.

Neuropathol Appl Neurobiol. 2004 Oct;30(5):532-9.PMID: 15488029 [PubMed - indexed for MEDLINE]Related articles

Estrogen and androgen protection of human neurons against intracellular amyloid beta1-42 toxicity through heat shock protein 70.

Zhang Y, Champagne N, Beitel LK, Goodyer CG, Trifiro M, LeBlanc A.

J Neurosci. 2004 Jun 9;24(23):5315-21.PMID: 15190103 [PubMed - indexed for MEDLINE]Related articlesFree article

Proteasomal degradation of caspase-6 in 17beta-estradiol-treated neurons.

Tounekti O, Zhang Y, Klaiman G, Goodyer CG, LeBlanc A.

J Neurochem. 2004 May;89(3):561-8.PMID: 15086513 [PubMed - indexed for MEDLINE]Related articles

Developmental changes in the expression of somatostatin receptors (1-5) in the brain, hypothalamus, pituitary and spinal cord of the human fetus.

Goodyer CG, Grigorakis SI, Patel YC, Kumar U.

Neuroscience. 2004;125(2):441-8.PMID: 15062986 [PubMed - indexed for MEDLINE]Related articles

Epigenetic silencing of the HIC-1 gene in human medulloblastomas.

Waha A, Waha A, Koch A, Meyer-Puttlitz B, Weggen S, Sörensen N, Tonn JC, Albrecht S, Goodyer CG, Berthold F, Wiestler OD, Pietsch T.

J Neuropathol Exp Neurol. 2003 Nov;62(11):1192-201.PMID: 14656076 [PubMed - indexed for MEDLINE]Related articles

Pitx1 in vivo promoter activity and mechanisms of positive autoregulation.

Goodyer CG, Tremblay JJ, Paradis FW, Marcil A, Lanctôt C, Gauthier Y, Drouin J.

Neuroendocrinology. 2003 Sep;78(3):129-37.PMID: 14512705 [PubMed - indexed for MEDLINE]Related articles

Cytosolic prion protein is not toxic and protects against Bax-mediated cell death in human primary neurons.

Roucou X, Guo Q, Zhang Y, Goodyer CG, LeBlanc AC.

J Biol Chem. 2003 Oct 17;278(42):40877-81. Epub 2003 Aug 12.PMID: 12917444 [PubMed - indexed for MEDLINE]Related articlesFree article

p75 neurotrophin receptor protects primary cultures of human neurons against extracellular amyloid beta peptide cytotoxicity.

Zhang Y, Hong Y, Bounhar Y, Blacker M, Roucou X, Tounekti O, Vereker E, Bowers WJ, Federoff HJ, Goodyer CG, LeBlanc A.

J Neurosci. 2003 Aug 13;23(19):7385-94.PMID: 12917374 [PubMed - indexed for MEDLINE]Related articlesFree article

Vulnerability of human neurons to T cell-mediated cytotoxicity.

Giuliani F, Goodyer CG, Antel JP, Yong VW.

J Immunol. 2003 Jul 1;171(1):368-79.PMID: 12817020 [PubMed - indexed for MEDLINE]Related articlesFree article

Exploitation of astrocytes by glioma cells to facilitate invasiveness: a mechanism involving matrix metalloproteinase-2 and the urokinase-type plasminogen activator-plasmin cascade.

Le DM, Besson A, Fogg DK, Choi KS, Waisman DM, Goodyer CG, Rewcastle B, Yong VW.

J Neurosci. 2003 May 15;23(10):4034-43.PMID: 12764090 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of human Dickkopf-1, an antagonist of wingless/WNT signaling, in human hepatoblastomas and Wilms' tumors.

Wirths O, Waha A, Weggen S, Schirmacher P, Kühne T, Goodyer CG, Albrecht S, Von Schweinitz D, Pietsch T.

Lab Invest. 2003 Mar;83(3):429-34.PMID: 12649343 [PubMed - indexed for MEDLINE]Related articles

Effect of tumor necrosis factor-alpha converting enzyme (TACE) and metalloprotease inhibitor on amyloid precursor protein metabolism in human neurons.

Blacker M, Noe MC, Carty TJ, Goodyer CG, LeBlanc AC.

J Neurochem. 2002 Dec;83(6):1349-57.PMID: 12472889 [PubMed - indexed for MEDLINE]Related articles

Alu elements in human growth hormone receptor gene 5' untranslated region exons.

Goodyer CG, Zheng H, Hendy GN.

J Mol Endocrinol. 2001 Dec;27(3):357-66.PMID: 11719288 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of the growth hormone receptor in human dermal fibroblasts and liver during development.

Goodyer CG, Figueiredo RM, Krackovitch S, De Souza Li L, Manalo JA, Zogopoulos G.

Am J Physiol Endocrinol Metab. 2001 Dec;281(6):E1213-20.PMID: 11701436 [PubMed - indexed for MEDLINE]Related articlesFree article

Galphas transcripts are biallelically expressed in the human kidney cortex: implications for pseudohypoparathyroidism type 1b.

Zheng H, Radeva G, McCann JA, Hendy GN, Goodyer CG.

J Clin Endocrinol Metab. 2001 Oct;86(10):4627-9.PMID: 11600515 [PubMed - indexed for MEDLINE]Related articlesFree article

17-beta-estradiol induces an inhibitor of active caspases.

Zhang Y, Tounekti O, Akerman B, Goodyer CG, LeBlanc A.

J Neurosci. 2001 Oct 15;21(20):RC176.PMID: 11588206 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence against GRB10 as the gene responsible for Silver-Russell syndrome.

McCann JA, Zheng H, Islam A, Goodyer CG, Polychronakos C.

Biochem Biophys Res Commun. 2001 Sep 7;286(5):943-8.PMID: 11527390 [PubMed - indexed for MEDLINE]Related articles

Prion protein protects human neurons against Bax-mediated apoptosis.

Bounhar Y, Zhang Y, Goodyer CG, LeBlanc A.

J Biol Chem. 2001 Oct 19;276(42):39145-9. Epub 2001 Aug 24.PMID: 11522774 [PubMed - indexed for MEDLINE]Related articlesFree article

GT repeat polymorphism in the 5' flanking region of the human growth hormone receptor gene.

Hadjiyannakis S, Zheng H, Hendy GN, Goodyer CG.

Mol Cell Probes. 2001 Aug;15(4):239-42.PMID: 11513560 [PubMed - indexed for MEDLINE]Related articles

Class III alleles of the variable number of tandem repeat insulin polymorphism associated with silencing of thymic insulin predispose to type 1 diabetes.

Vafiadis P, Ounissi-Benkalha H, Palumbo M, Grabs R, Rousseau M, Goodyer CG, Polychronakos C.

J Clin Endocrinol Metab. 2001 Aug;86(8):3705-10.PMID: 11502799 [PubMed - indexed for MEDLINE]Related articlesFree article

Organization and evolution of the human growth hormone receptor gene 5'-flanking region.

Goodyer CG, Zogopoulos G, Schwartzbauer G, Zheng H, Hendy GN, Menon RK.

Endocrinology. 2001 May;142(5):1923-34.PMID: 11316758 [PubMed - indexed for MEDLINE]Related articlesFree article

Alternative promoter usage and splicing of ZNF74 multifinger gene produce protein isoforms with a different repressor activity and nuclear partitioning.

Côté F, Boisvert FM, Grondin B, Bazinet M, Goodyer CG, Bazett-Jones DP, Aubry M.

DNA Cell Biol. 2001 Mar;20(3):159-73.PMID: 11313019 [PubMed - indexed for MEDLINE]Related articles

p57(KIP2) is not mutated in hepatoblastoma but shows increased transcriptional activity in a comparative analysis of the three imprinted genes p57(KIP2), IGF2, and H19.

Hartmann W, Waha A, Koch A, Goodyer CG, Albrecht S, von Schweinitz D, Pietsch T.

Am J Pathol. 2000 Oct;157(4):1393-403.PMID: 11021841 [PubMed - indexed for MEDLINE]Related articlesFree article

Interleukin-1 is a key regulator of matrix metalloproteinase-9 expression in human neurons in culture and following mouse brain trauma in vivo.

Vecil GG, Larsen PH, Corley SM, Herx LM, Besson A, Goodyer CG, Yong VW.

J Neurosci Res. 2000 Jul 15;61(2):212-24.PMID: 10878594 [PubMed - indexed for MEDLINE]Related articles

Transcriptional properties of Ptx1 and Ptx2 isoforms.

Tremblay JJ, Goodyer CG, Drouin J.

Neuroendocrinology. 2000 May;71(5):277-86.PMID: 10859489 [PubMed - indexed for MEDLINE]Related articles

Methylation patterns of human parathyroid hormone (PTH)/PTH-related peptide receptor gene promoters are established several weeks prior to onset of their function.

Bettoun JD, Kwan MY, Minagawa M, Alpert LC, Goodyer CG, Hendy GN, Goltzman D, White JH.

Biochem Biophys Res Commun. 2000 Jan 19;267(2):482-7.PMID: 10631087 [PubMed - indexed for MEDLINE]Related articles

The baboon: a model for the study of primate growth hormone receptor gene expression during development.

Zogopoulos G, Nathanielsz P, Hendy GN, Goodyer CG.

J Mol Endocrinol. 1999 Aug;23(1):67-75.PMID: 10425448 [PubMed - indexed for MEDLINE]Related articlesFree article