PubMed

Analysis of mouse models of cytochrome c oxidase deficiency due to mutations in Sco2.

Yang H, Brosel S, Acin-Perez R, Slavkovich V, Nishino I, Khan R, Goldberg IJ, Graziano J, Manfredi G, Schon EA.

Hum Mol Genet. 2009 Oct 16. [Epub ahead of print]PMID: 19837698 [PubMed - as supplied by publisher]Related articles

DGAT1 expression increases heart triglyceride content but ameliorates lipotoxicity.

Liu L, Shi X, Bharadwaj KG, Ikeda S, Yamashita H, Yagyu H, Schaffer JE, Yu YH, Goldberg IJ.

J Biol Chem. 2009 Sep 24. [Epub ahead of print]PMID: 19778901 [PubMed - as supplied by publisher]Related articles

Paradoxical coupling of triglyceride synthesis and fatty acid oxidation in skeletal muscle overexpressing DGAT1.

Liu L, Shi X, Choi CS, Shulman GI, Klaus K, Nair KS, Schwartz GJ, Zhang Y, Goldberg IJ, Yu YH.

Diabetes. 2009 Nov;58(11):2516-24. Epub 2009 Aug 12.PMID: 19675136 [PubMed - in process]Related articles

Cholesterol ester transfer protein inhibition: understanding the problems.

Goldberg IJ.

J Cardiovasc Pharmacol. 2009 Jul;54(1):1-2. No abstract available. PMID: 19617777 [PubMed - in process]Related articles

Actein activates stress- and statin-associated responses and is bioavailable in Sprague-Dawley rats.

Einbond LS, Soffritti M, Esposti DD, Park T, Cruz E, Su T, Wu HA, Wang X, Zhang YJ, Ham J, Goldberg IJ, Kronenberg F, Vladimirova A.

Fundam Clin Pharmacol. 2009 Jun;23(3):311-21.PMID: 19527300 [PubMed - indexed for MEDLINE]Related articles

Serine palmitoyltransferase (SPT) deficient mice absorb less cholesterol.

Li Z, Park TS, Li Y, Pan X, Iqbal J, Lu D, Tang W, Yu L, Goldberg IJ, Hussain MM, Jiang XC.

Biochim Biophys Acta. 2009 Apr;1791(4):297-306. Epub 2009 Jan 29.PMID: 19416652 [PubMed - indexed for MEDLINE]Related articles

Hypertriglyceridemia: impact and treatment.

Goldberg IJ.

Endocrinol Metab Clin North Am. 2009 Mar;38(1):137-49. Review.PMID: 19217516 [PubMed - indexed for MEDLINE]Related articles

Hypertriglyceridemia-induced pancreatitis created by oral estrogen and in vitro fertilization ovulation induction.

Lee J, Goldberg IJ.

J Clin Lipidol. 2008 Feb;2(1):63-66.PMID: 19190717 [PubMed]Related articlesFree article

Regulation of fatty acid uptake into tissues: lipoprotein lipase- and CD36-mediated pathways.

Goldberg IJ, Eckel RH, Abumrad NA.

J Lipid Res. 2009 Apr;50 Suppl:S86-90. Epub 2008 Nov 24.PMID: 19033209 [PubMed - indexed for MEDLINE]Related articles

Challenges to the diagnosis, evaluation, treatment, and management of clustered cardiometabolic risk factors.

Wilson PW, Black HR, Fabricatore AN, Goldberg IJ.

J Cardiometab Syndr. 2008 Summer;3(3):177-82.PMID: 18983336 [PubMed - indexed for MEDLINE]Related articles

Regulation of plasma fructose and mortality in mice by the aldose reductase inhibitor lidorestat.

Noh HL, Hu Y, Park TS, DiCioccio T, Nichols AJ, Okajima K, Homma S, Goldberg IJ.

J Pharmacol Exp Ther. 2009 Feb;328(2):496-503. Epub 2008 Oct 30.PMID: 18974362 [PubMed - indexed for MEDLINE]Related articlesFree article

Skeletal muscle-specific deletion of lipoprotein lipase enhances insulin signaling in skeletal muscle but causes insulin resistance in liver and other tissues.

Wang H, Knaub LA, Jensen DR, Young Jung D, Hong EG, Ko HJ, Coates AM, Goldberg IJ, de la Houssaye BA, Janssen RC, McCurdy CE, Rahman SM, Soo Choi C, Shulman GI, Kim JK, Friedman JE, Eckel RH.

Diabetes. 2009 Jan;58(1):116-24. Epub 2008 Oct 24.PMID: 18952837 [PubMed - indexed for MEDLINE]Related articlesFree article

ABCG1 and HDL protect against endothelial dysfunction in mice fed a high-cholesterol diet.

Terasaka N, Yu S, Yvan-Charvet L, Wang N, Mzhavia N, Langlois R, Pagler T, Li R, Welch CL, Goldberg IJ, Tall AR.

J Clin Invest. 2008 Nov;118(11):3701-13. Epub 2008 Oct 16.PMID: 18924609 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardiac metabolic compensation to hypertension requires lipoprotein lipase.

Yamashita H, Bharadwaj KG, Ikeda S, Park TS, Goldberg IJ.

Am J Physiol Endocrinol Metab. 2008 Sep;295(3):E705-13. Epub 2008 Jul 22.PMID: 18647880 [PubMed - indexed for MEDLINE]Related articlesFree article

Ceramide is a cardiotoxin in lipotoxic cardiomyopathy.

Park TS, Hu Y, Noh HL, Drosatos K, Okajima K, Buchanan J, Tuinei J, Homma S, Jiang XC, Abel ED, Goldberg IJ.

J Lipid Res. 2008 Oct;49(10):2101-12. Epub 2008 May 30.PMID: 18515784 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipoproteini lipase-derived fatty acids: physiology and dysfunction.

Lee J, Goldberg IJ.

Curr Hypertens Rep. 2007 Dec;9(6):462-6. Review.PMID: 18367009 [PubMed - indexed for MEDLINE]Related articles

The molecular basis of retinoid absorption: a genetic dissection.

Wongsiriroj N, Piantedosi R, Palczewski K, Goldberg IJ, Johnston TP, Li E, Blaner WS.

J Biol Chem. 2008 May 16;283(20):13510-9. Epub 2008 Mar 17.PMID: 18348983 [PubMed - indexed for MEDLINE]Related articlesFree article

Decreased lipoprotein clearance is responsible for increased cholesterol in LDL receptor knockout mice with streptozotocin-induced diabetes.

Goldberg IJ, Hu Y, Noh HL, Wei J, Huggins LA, Rackmill MG, Hamai H, Reid BN, Blaner WS, Huang LS.

Diabetes. 2008 Jun;57(6):1674-82. Epub 2008 Mar 17.PMID: 18346984 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatic overexpression of hormone-sensitive lipase and adipose triglyceride lipase promotes fatty acid oxidation, stimulates direct release of free fatty acids, and ameliorates steatosis.

Reid BN, Ables GP, Otlivanchik OA, Schoiswohl G, Zechner R, Blaner WS, Goldberg IJ, Schwabe RF, Chua SC Jr, Huang LS.

J Biol Chem. 2008 May 9;283(19):13087-99. Epub 2008 Mar 12.PMID: 18337240 [PubMed - indexed for MEDLINE]Related articlesFree article

In vivo arterial lipoprotein lipase expression augments inflammatory responses and impairs vascular dilatation.

Takahashi M, Hiyama Y, Yokoyama M, Yu S, Hu Y, Melford K, Bensadoun A, Goldberg IJ.

Arterioscler Thromb Vasc Biol. 2008 Mar;28(3):455-62. Epub 2008 Feb 7.PMID: 18258818 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of diabetes on murine lipoproteins and vascular disease.

Dansky HM, Goldberg IJ.

Curr Drug Targets. 2007 Nov;8(11):1196-202. Review.PMID: 18045098 [PubMed - indexed for MEDLINE]Related articles

Cardiomyocyte expression of PPARgamma leads to cardiac dysfunction in mice.

Son NH, Park TS, Yamashita H, Yokoyama M, Huggins LA, Okajima K, Homma S, Szabolcs MJ, Huang LS, Goldberg IJ.

J Clin Invest. 2007 Oct;117(10):2791-801.PMID: 17823655 [PubMed - indexed for MEDLINE]Related articlesFree article

Recipes for creating animal models of diabetic cardiovascular disease.

Hsueh W, Abel ED, Breslow JL, Maeda N, Davis RC, Fisher EA, Dansky H, McClain DA, McIndoe R, Wassef MK, Rabadán-Diehl C, Goldberg IJ.

Circ Res. 2007 May 25;100(10):1415-27. Review.PMID: 17525381 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipids in the heart: a source of fuel and a source of toxins.

Park TS, Yamashita H, Blaner WS, Goldberg IJ.

Curr Opin Lipidol. 2007 Jun;18(3):277-82. Review.PMID: 17495601 [PubMed - indexed for MEDLINE]Related articles

Effects of lipoprotein lipase and statins on cholesterol uptake into heart and skeletal muscle.

Yokoyama M, Seo T, Park T, Yagyu H, Hu Y, Son NH, Augustus AS, Vikramadithyan RK, Ramakrishnan R, Pulawa LK, Eckel RH, Goldberg IJ.

J Lipid Res. 2007 Mar;48(3):646-55. Epub 2006 Dec 22.PMID: 17189607 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardiac metabolism and mechanics are altered by genetic loss of lipoprotein triglyceride lipolysis.

Noh HL, Yamashita H, Goldberg IJ.

Cardiovasc Drugs Ther. 2006 Dec;20(6):441-4. Review.PMID: 17139480 [PubMed - indexed for MEDLINE]Related articles

Inhibition of pancreatic lipase by poloxamer 407 may provide an adjunct treatment strategy for weight loss.

Johnston TP, Goldberg IJ.

J Pharm Pharmacol. 2006 Aug;58(8):1099-105.PMID: 16872557 [PubMed - indexed for MEDLINE]Related articles

Addition of dietary fat to cholesterol in the diets of LDL receptor knockout mice: effects on plasma insulin, lipoproteins, and atherosclerosis.

Wu L, Vikramadithyan R, Yu S, Pau C, Hu Y, Goldberg IJ, Dansky HM.

J Lipid Res. 2006 Oct;47(10):2215-22. Epub 2006 Jul 13.PMID: 16840797 [PubMed - indexed for MEDLINE]Related articlesFree article

Diabetic vascular disease: an experimental objective.

Goldberg IJ, Dansky HM.

Arterioscler Thromb Vasc Biol. 2006 Aug;26(8):1693-701. Epub 2006 Jun 8. Review.PMID: 16763160 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute lipoprotein lipase deletion in adult mice leads to dyslipidemia and cardiac dysfunction.

Noh HL, Okajima K, Molkentin JD, Homma S, Goldberg IJ.

Am J Physiol Endocrinol Metab. 2006 Oct;291(4):E755-60. Epub 2006 May 9. Erratum in: Am J Physiol Endocrinol Metab. 2007 Jan;292(1):E367. Homma, Sunichi [corrected to Homma, Shunichi]. PMID: 16684851 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanism of glucose intolerance in mice with dominant negative mutation of CEACAM1.

Park SY, Cho YR, Kim HJ, Hong EG, Higashimori T, Lee SJ, Goldberg IJ, Shulman GI, Najjar SM, Kim JK.

Am J Physiol Endocrinol Metab. 2006 Sep;291(3):E517-24. Epub 2006 Apr 25.PMID: 16638824 [PubMed - indexed for MEDLINE]Related articlesFree article

Ins and outs modulating hepatic triglyceride and development of nonalcoholic fatty liver disease.

Goldberg IJ, Ginsberg HN.

Gastroenterology. 2006 Apr;130(4):1343-6. Review. No abstract available. PMID: 16618425 [PubMed - indexed for MEDLINE]Related articles

Loss of lipoprotein lipase-derived fatty acids leads to increased cardiac glucose metabolism and heart dysfunction.

Augustus AS, Buchanan J, Park TS, Hirata K, Noh HL, Sun J, Homma S, D'armiento J, Abel ED, Goldberg IJ.

J Biol Chem. 2006 Mar 31;281(13):8716-23. Epub 2006 Jan 12.PMID: 16410253 [PubMed - indexed for MEDLINE]Related articlesFree article

Human aldose reductase expression accelerates diabetic atherosclerosis in transgenic mice.

Vikramadithyan RK, Hu Y, Noh HL, Liang CP, Hallam K, Tall AR, Ramasamy R, Goldberg IJ.

J Clin Invest. 2005 Sep;115(9):2434-43. Epub 2005 Aug 25.PMID: 16127462 [PubMed - indexed for MEDLINE]Related articlesFree article

Retinoid absorption and storage is impaired in mice lacking lecithin:retinol acyltransferase (LRAT).

O'Byrne SM, Wongsiriroj N, Libien J, Vogel S, Goldberg IJ, Baehr W, Palczewski K, Blaner WS.

J Biol Chem. 2005 Oct 21;280(42):35647-57. Epub 2005 Aug 22.PMID: 16115871 [PubMed - indexed for MEDLINE]Related articlesFree article

Perfusion of hearts with triglyceride-rich particles reproduces the metabolic abnormalities in lipotoxic cardiomyopathy.

Pillutla P, Hwang YC, Augustus A, Yokoyama M, Yagyu H, Johnston TP, Kaneko M, Ramasamy R, Goldberg IJ.

Am J Physiol Endocrinol Metab. 2005 Jun;288(6):E1229-35. Epub 2005 Feb 8.PMID: 15701679 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator-activated receptor agonists modulate heart function in transgenic mice with lipotoxic cardiomyopathy.

Vikramadithyan RK, Hirata K, Yagyu H, Hu Y, Augustus A, Homma S, Goldberg IJ.

J Pharmacol Exp Ther. 2005 May;313(2):586-93. Epub 2005 Jan 25.PMID: 15671204 [PubMed - indexed for MEDLINE]Related articlesFree article

Pancreatic beta-cell lipoprotein lipase independently regulates islet glucose metabolism and normal insulin secretion.

Pappan KL, Pan Z, Kwon G, Marshall CA, Coleman T, Goldberg IJ, McDaniel ML, Semenkovich CF.

J Biol Chem. 2005 Mar 11;280(10):9023-9. Epub 2005 Jan 6.PMID: 15637076 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular interactions leading to lipoprotein retention and the initiation of atherosclerosis.

Khalil MF, Wagner WD, Goldberg IJ.

Arterioscler Thromb Vasc Biol. 2004 Dec;24(12):2211-8. Epub 2004 Oct 7. Review.PMID: 15472124 [PubMed - indexed for MEDLINE]Related articlesFree article

Statin inhibition of Fc receptor-mediated phagocytosis by macrophages is modulated by cell activation and cholesterol.

Loike JD, Shabtai DY, Neuhut R, Malitzky S, Lu E, Husemann J, Goldberg IJ, Silverstein SC.

Arterioscler Thromb Vasc Biol. 2004 Nov;24(11):2051-6. Epub 2004 Sep 2.PMID: 15345508 [PubMed - indexed for MEDLINE]Related articlesFree article

Why does diabetes increase atherosclerosis? I don't know!

Goldberg IJ.

J Clin Invest. 2004 Sep;114(5):613-5.PMID: 15343377 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipoprotein lipase and its role in regulation of plasma lipoproteins and cardiac risk.

Otarod JK, Goldberg IJ.

Curr Atheroscler Rep. 2004 Sep;6(5):335-42. Review.PMID: 15296698 [PubMed - indexed for MEDLINE]Related articles

Atherosclerosis in perlecan heterozygous mice.

Vikramadithyan RK, Kako Y, Chen G, Hu Y, Arikawa-Hirasawa E, Yamada Y, Goldberg IJ.

J Lipid Res. 2004 Oct;45(10):1806-12. Epub 2004 Jul 16.PMID: 15258195 [PubMed - indexed for MEDLINE]Related articlesFree article

Inflammatory cytokines and fatty acids regulate endothelial cell heparanase expression.

Chen G, Wang D, Vikramadithyan R, Yagyu H, Saxena U, Pillarisetti S, Goldberg IJ.

Biochemistry. 2004 May 4;43(17):4971-7.PMID: 15109255 [PubMed - indexed for MEDLINE]Related articles

Cardiac-specific knock-out of lipoprotein lipase alters plasma lipoprotein triglyceride metabolism and cardiac gene expression.

Augustus A, Yagyu H, Haemmerle G, Bensadoun A, Vikramadithyan RK, Park SY, Kim JK, Zechner R, Goldberg IJ.

J Biol Chem. 2004 Jun 11;279(24):25050-7. Epub 2004 Mar 17.PMID: 15028738 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of streptozotocin-induced diabetes in apolipoprotein AI deficient mice.

Goldberg IJ, Isaacs A, Sehayek E, Breslow JL, Huang LS.

Atherosclerosis. 2004 Jan;172(1):47-53.PMID: 14709356 [PubMed - indexed for MEDLINE]Related articles

Apolipoprotein B production reduces lipotoxic cardiomyopathy: studies in heart-specific lipoprotein lipase transgenic mouse.

Yokoyama M, Yagyu H, Hu Y, Seo T, Hirata K, Homma S, Goldberg IJ.

J Biol Chem. 2004 Feb 6;279(6):4204-11. Epub 2003 Nov 21.PMID: 14634011 [PubMed - indexed for MEDLINE]Related articlesFree article

Mice expressing only covalent dimeric heparin binding-deficient lipoprotein lipase: muscles inefficiently secrete dimeric enzyme.

Lutz EP, Kako Y, Yagyu H, Heeren J, Marks S, Wright T, Melford K, Ben-Zeev O, Radner H, Merkel M, Bensadoun A, Wong H, Goldberg IJ.

J Biol Chem. 2004 Jan 2;279(1):238-44. Epub 2003 Oct 21.PMID: 14570890 [PubMed - indexed for MEDLINE]Related articlesFree article

Poloxamer 407-mediated alterations in the activities of enzymes regulating lipid metabolism in rats.

Wasan KM, Subramanian R, Kwong M, Goldberg IJ, Wright T, Johnston TP.

J Pharm Pharm Sci. 2003 May-Aug;6(2):189-97.PMID: 12935429 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipoprotein lipase (LpL) on the surface of cardiomyocytes increases lipid uptake and produces a cardiomyopathy.

Yagyu H, Chen G, Yokoyama M, Hirata K, Augustus A, Kako Y, Seo T, Hu Y, Lutz EP, Merkel M, Bensadoun A, Homma S, Goldberg IJ.

J Clin Invest. 2003 Feb;111(3):419-26.PMID: 12569168 [PubMed - indexed for MEDLINE]Related articlesFree article