PubMed

Mechanical forces and TGF{beta}1 reduce podocyte adhesion through {alpha}3{beta}1 integrin downregulation.

Dessapt C, Baradez MO, Hayward A, Dei Cas A, Thomas SM, Viberti G, Gnudi L.

Nephrol Dial Transplant. 2009 Sep;24(9):2645-55. Epub 2009 May 6.PMID: 19420102 [PubMed - in process]Related articles

Roles of angiopoietins in kidney development and disease.

Woolf AS, Gnudi L, Long DA.

J Am Soc Nephrol. 2009 Feb;20(2):239-44. Epub 2008 Sep 17. Review.PMID: 18799719 [PubMed - indexed for MEDLINE]Related articles

Molecular mechanisms of proteinuria in diabetes.

Gnudi L.

Biochem Soc Trans. 2008 Oct;36(Pt 5):946-9.PMID: 18793166 [PubMed - indexed for MEDLINE]Related articles

Inducible overexpression of sFlt-1 in podocytes ameliorates glomerulopathy in diabetic mice.

Ku CH, White KE, Dei Cas A, Hayward A, Webster Z, Bilous R, Marshall S, Viberti G, Gnudi L.

Diabetes. 2008 Oct;57(10):2824-33. Epub 2008 Jul 22.PMID: 18647955 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiopoietin-1 therapy enhances fibrosis and inflammation following folic acid-induced acute renal injury.

Long DA, Price KL, Ioffe E, Gannon CM, Gnudi L, White KE, Yancopoulos GD, Rudge JS, Woolf AS.

Kidney Int. 2008 Aug;74(3):300-9. Epub 2008 May 14.PMID: 18480750 [PubMed - indexed for MEDLINE]Related articles

ACCORD and ADVANCE: a tale of two studies on the merits of glycaemic control in type 2 diabetic patients.

Karalliedde J, Gnudi L.

Nephrol Dial Transplant. 2008 Jun;23(6):1796-8. Epub 2008 Apr 10. No abstract available. PMID: 18403430 [PubMed - indexed for MEDLINE]Related articles

Future strategies to prevent renal microvascular disease complications in diabetes.

Karalliedde J, Gnudi L.

Future Cardiol. 2008 Jan;4(1):77-83.PMID: 19804273 [PubMed - in process]

Serum intact parathyroid hormone in diabetic patients on haemodialysis: what is the treatment goal?

Gnudi L.

Nephrol Dial Transplant. 2008 Jan;23(1):24-6. Epub 2007 Dec 1. Review. No abstract available. PMID: 18056070 [PubMed - indexed for MEDLINE]Related articles

Fluorescence-based sensing of glucose using engineered glucose/galactose-binding protein: a comparison of fluorescence resonance energy transfer and environmentally sensitive dye labelling strategies.

Khan F, Gnudi L, Pickup JC.

Biochem Biophys Res Commun. 2008 Jan 4;365(1):102-6. Epub 2007 Oct 30.PMID: 17976368 [PubMed - indexed for MEDLINE]Related articles

Mechanical forces in diabetic kidney disease: a trigger for impaired glucose metabolism.

Gnudi L, Thomas SM, Viberti G.

J Am Soc Nephrol. 2007 Aug;18(8):2226-32. Epub 2007 Jul 18. Review.PMID: 17634438 [PubMed - indexed for MEDLINE]Related articlesFree article

Podocyte-specific expression of angiopoietin-2 causes proteinuria and apoptosis of glomerular endothelia.

Davis B, Dei Cas A, Long DA, White KE, Hayward A, Ku CH, Woolf AS, Bilous R, Viberti G, Gnudi L.

J Am Soc Nephrol. 2007 Aug;18(8):2320-9. Epub 2007 Jul 11.PMID: 17625119 [PubMed - indexed for MEDLINE]Related articlesFree article

The link between mechanical stretch and glucose metabolism--a conceptual advance in understanding diabetic (and non diabetic?) renal disease.

Gnudi L, Viberti G.

Nephrol Dial Transplant. 2007 Feb;22(2):318-21. Epub 2006 Nov 18. No abstract available. PMID: 17114798 [PubMed - indexed for MEDLINE]Related articlesFree article

The link between Glut-1 and hypertension in diabetic nephropathy.

Gnudi L, Raij L.

Curr Hypertens Rep. 2006 Apr;8(1):79-83. Review.PMID: 16600163 [PubMed - indexed for MEDLINE]Related articles

Glucose induces increases in levels of the transcriptional repressor Id2 via the hexosamine pathway.

Grønning LM, Tingsabadh R, Hardy K, Dalen KT, Jat PS, Gnudi L, Shepherd PR.

Am J Physiol Endocrinol Metab. 2006 Apr;290(4):E599-606. Epub 2005 Oct 18.PMID: 16234270 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose-dependent changes in NAD(P)H-related fluorescence lifetime of adipocytes and fibroblasts in vitro: potential for non-invasive glucose sensing in diabetes mellitus.

Evans ND, Gnudi L, Rolinski OJ, Birch DJ, Pickup JC.

J Photochem Photobiol B. 2005 Aug 1;80(2):122-9.PMID: 15908228 [PubMed - indexed for MEDLINE]Related articles

Mechanical stretch induces monocyte chemoattractant activity via an NF-kappaB-dependent monocyte chemoattractant protein-1-mediated pathway in human mesangial cells: inhibition by rosiglitazone.

Gruden G, Setti G, Hayward A, Sugden D, Duggan S, Burt D, Buckingham RE, Gnudi L, Viberti G.

J Am Soc Nephrol. 2005 Mar;16(3):688-96. Epub 2005 Jan 26.PMID: 15677312 [PubMed - indexed for MEDLINE]Related articlesFree article

Non-invasive glucose monitoring by NAD(P)H autofluorescence spectroscopy in fibroblasts and adipocytes: a model for skin glucose sensing.

Evans ND, Gnudi L, Rolinski OJ, Birch DJ, Pickup JC.

Diabetes Technol Ther. 2003;5(5):807-16.PMID: 14633346 [PubMed - indexed for MEDLINE]Related articles

GLUT-1 overexpression: Link between hemodynamic and metabolic factors in glomerular injury?

Gnudi L, Viberti G, Raij L, Rodriguez V, Burt D, Cortes P, Hartley B, Thomas S, Maestrini S, Gruden G.

Hypertension. 2003 Jul;42(1):19-24. Epub 2003 May 27.PMID: 12771048 [PubMed - indexed for MEDLINE]Related articlesFree article

P38 mitogen-activated protein kinase mediates hexosamine-induced TGFbeta1 mRNA expression in human mesangial cells.

Burt DJ, Gruden G, Thomas SM, Tutt P, Dell'Anna C, Viberti GC, Gnudi L.

Diabetologia. 2003 Apr;46(4):531-7. Epub 2003 Apr 5.PMID: 12679868 [PubMed - indexed for MEDLINE]Related articles

IGF-I induces vascular endothelial growth factor in human mesangial cells via a Src-dependent mechanism.

Gruden G, Araf S, Zonca S, Burt D, Thomas S, Gnudi L, Viberti G.

Kidney Int. 2003 Apr;63(4):1249-55.PMID: 12631341 [PubMed - indexed for MEDLINE]Related articles

Mechanical stretch-induced fibronectin and transforming growth factor-beta1 production in human mesangial cells is p38 mitogen-activated protein kinase-dependent.

Gruden G, Zonca S, Hayward A, Thomas S, Maestrini S, Gnudi L, Viberti GC.

Diabetes. 2000 Apr;49(4):655-61.PMID: 10871205 [PubMed - indexed for MEDLINE]Related articlesFree article

Vascular endothelial growth factor receptors in human mesangium in vitro and in glomerular disease.

Thomas S, Vanuystel J, Gruden G, Rodríguez V, Burt D, Gnudi L, Hartley B, Viberti G.

J Am Soc Nephrol. 2000 Jul;11(7):1236-43.PMID: 10864579 [PubMed - indexed for MEDLINE]Related articlesFree article

Interaction of angiotensin II and mechanical stretch on vascular endothelial growth factor production by human mesangial cells.

Gruden G, Thomas S, Burt D, Zhou W, Chusney G, Gnudi L, Viberti G.

J Am Soc Nephrol. 1999 Apr;10(4):730-7.PMID: 10203356 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of DNA synthesis by a farnesyltransferase inhibitor involves inhibition of the p70(s6k) pathway.

Law BK, Nørgaard P, Gnudi L, Kahn BB, Poulson HS, Moses HL.

J Biol Chem. 1999 Feb 19;274(8):4743-8.PMID: 9988711 [PubMed - indexed for MEDLINE]Related articlesFree article

Multiple signal transduction pathways link Na+/K+-ATPase to growth-related genes in cardiac myocytes. The roles of Ras and mitogen-activated protein kinases.

Kometiani P, Li J, Gnudi L, Kahn BB, Askari A, Xie Z.

J Biol Chem. 1998 Jun 12;273(24):15249-56.PMID: 9614140 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of the ras mitogen-activated protein kinase-ribosomal protein kinase pathway is not required for the repression of phosphoenolpyruvate carboxykinase gene transcription by insulin.

Sutherland C, Waltner-Law M, Gnudi L, Kahn BB, Granner DK.

J Biol Chem. 1998 Feb 6;273(6):3198-204.PMID: 9452431 [PubMed - indexed for MEDLINE]Related articlesFree article

Amelioration of insulin resistance in streptozotocin diabetic mice by transgenic overexpression of GLUT4 driven by an adipose-specific promoter.

Tozzo E, Gnudi L, Kahn BB.

Endocrinology. 1997 Apr;138(4):1604-11.PMID: 9075721 [PubMed - indexed for MEDLINE]Related articlesFree article

High-fat feeding impairs insulin-stimulated GLUT4 recruitment via an early insulin-signaling defect.

Zierath JR, Houseknecht KL, Gnudi L, Kahn BB.

Diabetes. 1997 Feb;46(2):215-23.PMID: 9000697 [PubMed - indexed for MEDLINE]Related articles

Adenovirus-mediated gene transfer of dominant negative ras(asn17) in 3T3L1 adipocytes does not alter insulin-stimulated P13-kinase activity or glucose transport.

Gnudi L, Frevert EU, Houseknecht KL, Erhardt P, Kahn BB.

Mol Endocrinol. 1997 Jan;11(1):67-76.PMID: 8994189 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of Ha-ras selectively in adipose tissue of transgenic mice. Evidence for enhanced sensitivity to insulin.

Houseknecht KL, Zhu AX, Gnudi L, Hamann A, Zierath JR, Tozzo E, Flier JS, Kahn BB.

J Biol Chem. 1996 May 10;271(19):11347-55.PMID: 8626688 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipose-specific overexpression of GLUT-4 in transgenic mice alters lipoprotein lipase activity.

Gnudi L, Jensen DR, Tozzo E, Eckel RH, Kahn BB.

Am J Physiol. 1996 Apr;270(4 Pt 2):R785-92.PMID: 8967408 [PubMed - indexed for MEDLINE]Related articles

Over-expression of GLUT4 selectively in adipose tissue in transgenic mice: implications for nutrient partitioning.

Gnudi L, Shepherd PR, Kahn BB.

Proc Nutr Soc. 1996 Mar;55(1B):191-9. Review.PMID: 8832791 [PubMed - indexed for MEDLINE]Related articles

Insulin regulation of phosphoenolpyruvate carboxykinase gene expression does not require activation of the Ras/mitogen-activated protein kinase signaling pathway.

Gabbay RA, Sutherland C, Gnudi L, Kahn BB, O'Brien RM, Granner DK, Flier JS.

J Biol Chem. 1996 Jan 26;271(4):1890-7.PMID: 8567635 [PubMed - indexed for MEDLINE]Related articlesFree article

Transgenic GLUT-4 overexpression in fat enhances glucose metabolism: preferential effect on fatty acid synthesis.

Tozzo E, Shepherd PR, Gnudi L, Kahn BB.

Am J Physiol. 1995 May;268(5 Pt 1):E956-64.PMID: 7762651 [PubMed - indexed for MEDLINE]Related articles

High level overexpression of glucose transporter-4 driven by an adipose-specific promoter is maintained in transgenic mice on a high fat diet, but does not prevent impaired glucose tolerance.

Gnudi L, Tozzo E, Shepherd PR, Bliss JL, Kahn BB.

Endocrinology. 1995 Mar;136(3):995-1002.PMID: 7867610 [PubMed - indexed for MEDLINE]Related articles

Alcohol intake impairs glucose counterregulation during acute insulin-induced hypoglycemia in IDDM patients. Evidence for a critical role of free fatty acids.

Avogaro A, Beltramello P, Gnudi L, Maran A, Valerio A, Miola M, Marin N, Crepaldi C, Confortin L, Costa F, et al.

Diabetes. 1993 Nov;42(11):1626-34.PMID: 8405705 [PubMed - indexed for MEDLINE]Related articles

Adipose cell hyperplasia and enhanced glucose disposal in transgenic mice overexpressing GLUT4 selectively in adipose tissue.

Shepherd PR, Gnudi L, Tozzo E, Yang H, Leach F, Kahn BB.

J Biol Chem. 1993 Oct 25;268(30):22243-6.PMID: 8226728 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of different plasma glucose concentrations on lipolytic and ketogenic responsiveness to epinephrine in type I (insulin-dependent) diabetic subjects.

Avogaro A, Gnudi L, Valerio A, Maran A, Miola M, Opportuno A, Tiengo A, Bier DM.

J Clin Endocrinol Metab. 1993 Apr;76(4):845-50.PMID: 8473394 [PubMed - indexed for MEDLINE]Related articles

Ketone body metabolism in NIDDM. Effect of sulfonylurea treatment.

Avogaro A, Valerio A, Gnudi L, Maran A, Zolli M, Duner E, Riccio A, Del Prato S, Tiengo A, Nosadini R.

Diabetes. 1992 Aug;41(8):968-74.PMID: 1628772 [PubMed - indexed for MEDLINE]Related articles

Forearm ketone body metabolism in normal and in insulin-dependent diabetic patients.

Avogaro A, Doria A, Gnudi L, Carraro A, Duner E, Brocco E, Tiengo A, Crepaldi G, Bier DM, Nosadini R.

Am J Physiol. 1992 Aug;263(2 Pt 1):E261-7.PMID: 1514605 [PubMed - indexed for MEDLINE]Related articles

The effects of different plasma insulin concentrations on lipolytic and ketogenic responses to epinephrine in normal and type 1 (insulin-dependent) diabetic humans.

Avogaro A, Valerio A, Gnudi L, Maran A, Miola M, Duner E, Marescotti C, Iori E, Tiengo A, Nosadini R.

Diabetologia. 1992 Feb;35(2):129-38.PMID: 1547916 [PubMed - indexed for MEDLINE]Related articles

Renal metabolism of C peptide in type I (insulin-dependent) diabetic patients.

Zavaroni I, Robaudo C, Mazza S, Gnudi L, Saffioti S, Lugari R, Gnudi A, Deferrari G.

J Diabet Complications. 1991 Apr-Sep;5(2-3):110-1. No abstract available. PMID: 1770013 [PubMed - indexed for MEDLINE]Related articles

Effects of chronic alcohol intake on carbohydrate and lipid metabolism in subjects with type II (non-insulin-dependent) diabetes.

Ben G, Gnudi L, Maran A, Gigante A, Duner E, Iori E, Tiengo A, Avogaro A.

Am J Med. 1991 Jan;90(1):70-6.PMID: 1986593 [PubMed - indexed for MEDLINE]Related articles

Habitual leisure-time physical activity is associated with differences in various risk factors for coronary artery disease.

Zavaroni I, Angelo Bonati P, Luchetti L, Bonora E, Buonanno G, Bergonzani M, Pagliara M, Gnudi L, Butturini L, Passeri M, et al.

J Intern Med. 1989 Dec;226(6):417-21.PMID: 2489226 [PubMed - indexed for MEDLINE]Related articles

Risk factors for coronary artery disease in healthy persons with hyperinsulinemia and normal glucose tolerance.

Zavaroni I, Bonora E, Pagliara M, Dall'Aglio E, Luchetti L, Buonanno G, Bonati PA, Bergonzani M, Gnudi L, Passeri M, et al.

N Engl J Med. 1989 Mar 16;320(11):702-6.PMID: 2646537 [PubMed - indexed for MEDLINE]Related articles