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Gm614 Protects Germinal Center B Cells From Death by Suppressing Caspase-1 Transcription in Lupus-Prone Mice.
He Y, Xu R, Zhai B, Zhou S, Wang X, Wang R. He Y, et al. Front Immunol. 2020 Oct 21;11:585726. doi: 10.3389/fimmu.2020.585726. eCollection 2020. Front Immunol. 2020. PMID: 33193409 Free PMC article.
We demonstrated that mechanistically, nuclear-localized Gm614 reduced caspase-1 expression in GC B cells by binding with caspase-1 promoter to suppress its activation. Our results suggest that Gm614 protects GC B cells from death by suppressing caspase-1 transcripti …
We demonstrated that mechanistically, nuclear-localized Gm614 reduced caspase-1 expression in GC B cells by binding with caspase-1 pr …
The C terminus of p73 is essential for hippocampal development.
Amelio I, Panatta E, Niklison-Chirou MV, Steinert JR, Agostini M, Morone N, Knight RA, Melino G. Amelio I, et al. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):15694-15701. doi: 10.1073/pnas.2000917117. Epub 2020 Jun 22. Proc Natl Acad Sci U S A. 2020. PMID: 32571922 Free PMC article.
Loss of p53 in mesenchymal stem cells promotes alteration of bone remodeling through negative regulation of osteoprotegerin.
Velletri T, Huang Y, Wang Y, Li Q, Hu M, Xie N, Yang Q, Chen X, Chen Q, Shou P, Gan Y, Candi E, Annicchiarico-Petruzzelli M, Agostini M, Yang H, Melino G, Shi Y, Wang Y. Velletri T, et al. Cell Death Differ. 2021 Jan;28(1):156-169. doi: 10.1038/s41418-020-0590-4. Epub 2020 Jul 21. Cell Death Differ. 2021. PMID: 32694652 Free PMC article.
TAp73 contributes to the oxidative stress response by regulating protein synthesis.
Marini A, Rotblat B, Sbarrato T, Niklison-Chirou MV, Knight JRP, Dudek K, Jones C, Bushell M, Knight RA, Amelio I, Willis AE, Melino G. Marini A, et al. Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):6219-6224. doi: 10.1073/pnas.1718531115. Epub 2018 May 29. Proc Natl Acad Sci U S A. 2018. PMID: 29844156 Free PMC article.
11 results