PubMed

Monotherapy with anti-LFA-1 monoclonal antibody promotes long-term survival of rat islet xenografts.

Tredget EB, Arefanian H, Gill RG, Rajotte RV, Rayat GR.

Cell Transplant. 2008;17(6):599-608.PMID: 18819248 [PubMed - indexed for MEDLINE]Related articles

Both innate and adaptive major histocompatibility complex class I-dependent immunity impair long-term islet xenograft survival.

Ramirez-Victorio F, Beilke JN, Gill RG.

Transplant Proc. 2008 Mar;40(2):557-8.PMID: 18374128 [PubMed - indexed for MEDLINE]Related articles

"Indirect" acute islet allograft destruction in nonobese diabetic mice is independent of donor major histocompatibility complex and requires host B lymphocytes.

Kupfer T, Beilke JN, Pham K, Buhrman J, Gill RG.

Transplant Proc. 2008 Mar;40(2):462-3.PMID: 18374102 [PubMed - indexed for MEDLINE]Related articles

Combination of anti-CD4 with anti-LFA-1 and anti-CD154 monoclonal antibodies promotes long-term survival and function of neonatal porcine islet xenografts in spontaneously diabetic NOD mice.

Arefanian H, Tredget EB, Rajotte RV, Korbutt GS, Gill RG, Rayat GR.

Cell Transplant. 2007;16(8):787-98.PMID: 18087999 [PubMed - indexed for MEDLINE]Related articles

Frontiers in nephrology: the varied faces of natural killer cells in transplantation--contributions to both allograft immunity and tolerance.

Beilke JN, Gill RG.

J Am Soc Nephrol. 2007 Aug;18(8):2262-7. Epub 2007 Jul 18. Review.PMID: 17634430 [PubMed - indexed for MEDLINE]Related articlesFree article

Islet allograft rejection by contact-dependent CD8+ T cells: perforin and FasL play alternate but obligatory roles.

Sleater M, Diamond AS, Gill RG.

Am J Transplant. 2007 Aug;7(8):1927-33.PMID: 17617855 [PubMed - indexed for MEDLINE]Related articles

Priming and effector dependence on insulin B:9-23 peptide in NOD islet autoimmunity.

Nakayama M, Beilke JN, Jasinski JM, Kobayashi M, Miao D, Li M, Coulombe MG, Liu E, Elliott JF, Gill RG, Eisenbarth GS.

J Clin Invest. 2007 Jul;117(7):1835-43.PMID: 17607359 [PubMed - indexed for MEDLINE]Related articlesFree article

Dominant negative mutant forms of the cAMP response element binding protein induce apoptosis and decrease the anti-apoptotic action of growth factors in human islets.

Sarkar SA, Gunter J, Bouchard R, Reusch JE, Wiseman A, Gill RG, Hutton JC, Pugazhenthi S.

Diabetologia. 2007 Aug;50(8):1649-59. Epub 2007 Jun 26.PMID: 17593347 [PubMed - indexed for MEDLINE]Related articles

Spontaneous allograft tolerance in B7-deficient mice independent of preexisting endogenous CD4+CD25+ regulatory T-cells.

Grazia TJ, Plenter RJ, Doan AN, Kelly BP, Weber SM, Kurche JS, Cushing SO, Gill RG, Pietra BA.

Transplantation. 2007 Jun 15;83(11):1449-58.PMID: 17565318 [PubMed - indexed for MEDLINE]Related articles

Progressive biliary destruction is independent of a functional tumor necrosis factor-alpha pathway in a rhesus rotavirus-induced murine model of biliary atresia.

Tucker RM, Hendrickson RJ, Mukaida N, Gill RG, Mack CL.

Viral Immunol. 2007 Spring;20(1):34-43.PMID: 17425419 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of indoleamine 2,3-dioxygenase by interferon-gamma in human islets.

Sarkar SA, Wong R, Hackl SI, Moua O, Gill RG, Wiseman A, Davidson HW, Hutton JC.

Diabetes. 2007 Jan;56(1):72-9.PMID: 17192467 [PubMed - indexed for MEDLINE]Related articlesFree article

Rosiglitazone promotes development of a novel adipocyte population from bone marrow-derived circulating progenitor cells.

Crossno JT Jr, Majka SM, Grazia T, Gill RG, Klemm DJ.

J Clin Invest. 2006 Dec;116(12):3220-8.PMID: 17143331 [PubMed - indexed for MEDLINE]Related articlesFree article

Cellular and humoral autoimmunity directed at bile duct epithelia in murine biliary atresia.

Mack CL, Tucker RM, Lu BR, Sokol RJ, Fontenot AP, Ueno Y, Gill RG.

Hepatology. 2006 Nov;44(5):1231-9.PMID: 17058262 [PubMed - indexed for MEDLINE]Related articlesFree article

Initial results of screening of nondiabetic organ donors for expression of islet autoantibodies.

Gianani R, Putnam A, Still T, Yu L, Miao D, Gill RG, Beilke J, Supon P, Valentine A, Iveson A, Dunn S, Eisenbarth GS, Hutton J, Gottlieb P, Wiseman A.

J Clin Endocrinol Metab. 2006 May;91(5):1855-61. Epub 2006 Feb 14.PMID: 16478822 [PubMed - indexed for MEDLINE]Related articlesFree article

LFA-1 (CD11a) as a therapeutic target.

Nicolls MR, Gill RG.

Am J Transplant. 2006 Jan;6(1):27-36.PMID: 16433753 [PubMed - indexed for MEDLINE]Related articles

Peripheral CD4 T-cell depletion is not sufficient to prevent ischemic acute renal failure.

Faubel S, Ljubanovic D, Poole B, Dursun B, He Z, Cushing S, Somerset H, Gill RG, Edelstein CL.

Transplantation. 2005 Sep 15;80(5):643-9.PMID: 16177639 [PubMed - indexed for MEDLINE]Related articles

NK cells promote islet allograft tolerance via a perforin-dependent mechanism.

Beilke JN, Kuhl NR, Van Kaer L, Gill RG.

Nat Med. 2005 Oct;11(10):1059-65. Epub 2005 Sep 11. Erratum in: Nat Med. 2006 Mar;12(3):367. PMID: 16155578 [PubMed - indexed for MEDLINE]Related articles

Perturbation of leukocyte function-associated antigen-1/intercellular adhesion molecule-1 results in differential outcomes in cardiac vs islet allograft survival.

Grazia TJ, Gill RG, Gelhaus HC Jr, Doan AN, Sleater ML, Pietra BA.

J Heart Lung Transplant. 2005 Sep;24(9):1410-4.PMID: 16143264 [PubMed - indexed for MEDLINE]Related articles

MHC-mismatched islet allografts are vulnerable to autoimmune recognition in vivo.

Kupfer TM, Crawford ML, Pham K, Gill RG.

J Immunol. 2005 Aug 15;175(4):2309-16.PMID: 16081800 [PubMed - indexed for MEDLINE]Related articlesFree article

Simultaneous LFA-1 and CD40 ligand antagonism prevents airway remodeling in orthotopic airway transplantation: implications for the role of respiratory epithelium as a modulator of fibrosis.

Murakawa T, Kerklo MM, Zamora MR, Wei Y, Gill RG, Henson PM, Grover FL, Nicolls MR.

J Immunol. 2005 Apr 1;174(7):3869-79.PMID: 15778341 [PubMed - indexed for MEDLINE]Related articlesFree article

Indefinite survival of neonatal porcine islet xenografts by simultaneous targeting of LFA-1 and CD154 or CD45RB.

Rayat GR, Gill RG.

Diabetes. 2005 Feb;54(2):443-51.PMID: 15677502 [PubMed - indexed for MEDLINE]Related articlesFree article

The immunobiology of pancreatic islet transplantation.

Coulombe M, Gill RG.

Adv Exp Med Biol. 2004;552:154-69. Review. No abstract available. PMID: 15622963 [PubMed - indexed for MEDLINE]Related articles

To help and help not.

Homann D, Gill RG.

Nat Immunol. 2004 Sep;5(9):878-80. No abstract available. PMID: 15334082 [PubMed - indexed for MEDLINE]Related articles

A major role for host MHC class I antigen presentation for promoting islet allograft survival.

Beilke J, Johnson Z, Kuhl N, Gill RG.

Transplant Proc. 2004 May;36(4):1173-4.PMID: 15194406 [PubMed - indexed for MEDLINE]Related articles

Distinct requirements for host CD80/CD86 costimulatory molecules in cardiac versus islet rejection.

Johnson Z, Beilke J, Pietra B, Kelly B, Gill RG.

Transplant Proc. 2004 May;36(4):1171-2.PMID: 15194405 [PubMed - indexed for MEDLINE]Related articles

A two-step model of acute CD4 T-cell mediated cardiac allograft rejection.

Grazia TJ, Pietra BA, Johnson ZA, Kelly BP, Plenter RJ, Gill RG.

J Immunol. 2004 Jun 15;172(12):7451-8.PMID: 15187123 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for a primary islet autoantigen (preproinsulin 1) for insulitis and diabetes in the nonobese diabetic mouse.

Moriyama H, Abiru N, Paronen J, Sikora K, Liu E, Miao D, Devendra D, Beilke J, Gianani R, Gill RG, Eisenbarth GS.

Proc Natl Acad Sci U S A. 2003 Sep 2;100(18):10376-81. Epub 2003 Aug 18.PMID: 12925730 [PubMed - indexed for MEDLINE]Related articlesFree article

Pancreatic islet xenotransplantation: barriers and prospects.

Rayat GR, Gill RG.

Curr Diab Rep. 2003 Aug;3(4):336-43. Review.PMID: 12866998 [PubMed - indexed for MEDLINE]Related articles

The degree of phylogenetic disparity of islet grafts dictates the reliance on indirect CD4 T-cell antigen recognition for rejection.

Rayat GR, Johnson ZA, Beilke JN, Korbutt GS, Rajotte RV, Gill RG.

Diabetes. 2003 Jun;52(6):1433-40.PMID: 12765954 [PubMed - indexed for MEDLINE]Related articlesFree article

Proteomics as a tool for discovery: proteins implicated in Alzheimer's disease are highly expressed in normal pancreatic islets.

Nicolls MR, D'Antonio JM, Hutton JC, Gill RG, Czwornog JL, Duncan MW.

J Proteome Res. 2003 Mar-Apr;2(2):199-205.PMID: 12716134 [PubMed - indexed for MEDLINE]Related articles

CD4-dependent generation of dominant transplantation tolerance induced by simultaneous perturbation of CD154 and LFA-1 pathways.

Nicolls MR, Coulombe M, Beilke J, Gelhaus HC, Gill RG.

J Immunol. 2002 Nov 1;169(9):4831-9.PMID: 12391193 [PubMed - indexed for MEDLINE]Related articlesFree article

Interferon-gamma is not a universal requirement for islet allograft survival.

Nicolls MR, Coulombe M, Diamond AS, Beilke J, Gill RG.

Transplantation. 2002 Aug 27;74(4):472-7.PMID: 12352904 [PubMed - indexed for MEDLINE]Related articles

Use of small animal models for screening immunoisolation approaches to cellular transplantation.

Gill RG.

Ann N Y Acad Sci. 2001 Nov;944:35-46. Review.PMID: 11797684 [PubMed - indexed for MEDLINE]Related articles

Donor IFN-gamma receptors are critical for acute CD4(+) T cell-mediated cardiac allograft rejection.

Wiseman AC, Pietra BA, Kelly BP, Rayat GR, Rizeq M, Gill RG.

J Immunol. 2001 Nov 1;167(9):5457-63.PMID: 11673565 [PubMed - indexed for MEDLINE]Related articlesFree article

The basis of immunogenicity of endocrine allografts.

Nicolls MR, Coulombe M, Gill RG.

Crit Rev Immunol. 2001;21(1-3):87-101. Review.PMID: 11642616 [PubMed - indexed for MEDLINE]Related articles

Immunobiology of cardiac allograft and xenograft transplantation.

Pietra BA, Gill RG.

Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2001;4:123-57. Review.PMID: 11460981 [PubMed - indexed for MEDLINE]Related articles

alpha4 integrin in islet allograft rejection.

Stegall MD, Dean PG, Ninova D, Cohen AJ, Shepard GM, Gup C, Gill RG.

Transplantation. 2001 Jun 15;71(11):1549-55.PMID: 11435963 [PubMed - indexed for MEDLINE]Related articles

CD4 T cell-mediated cardiac allograft rejection requires donor but not host MHC class II.

Pietra BA, Wiseman A, Bolwerk A, Rizeq M, Gill RG.

J Clin Invest. 2000 Oct;106(8):1003-10.PMID: 11032860 [PubMed - indexed for MEDLINE]Related articlesFree article

An essential contribution by IFN-gamma to CD8+ T cell-mediated rejection of pancreatic islet allografts.

Diamond AS, Gill RG.

J Immunol. 2000 Jul 1;165(1):247-55.PMID: 10861058 [PubMed - indexed for MEDLINE]Related articlesFree article

Anti-LFA-1 therapy induces long-term islet allograft acceptance in the absence of IFN-gamma or IL-4.

Nicolls MR, Coulombe M, Yang H, Bolwerk A, Gill RG.

J Immunol. 2000 Apr 1;164(7):3627-34.PMID: 10725719 [PubMed - indexed for MEDLINE]Related articlesFree article

Bioartificial organs and acceptable risk.

Hunkeler D, Sun AM, Korbutt GS, Rajotte RV, Gill RG, Calafiore R, Morel P.

Nat Biotechnol. 1999 Nov;17(11):1045. No abstract available. PMID: 10545868 [PubMed - indexed for MEDLINE]Related articles

Cellular immune response to phogrin in the NOD mouse: cloned T-cells cause destruction of islet transplants.

Kelemen K, Crawford ML, Gill RG, Hutton JC, Wegmann D.

Diabetes. 1999 Aug;48(8):1529-34.PMID: 10426369 [PubMed - indexed for MEDLINE]Related articlesFree article

Antigen presentation pathways for immunity to islet transplants. Relevance to immunoisolation.

Gill RG.

Ann N Y Acad Sci. 1999 Jun 18;875:255-60. Review.PMID: 10415572 [PubMed - indexed for MEDLINE]Related articles

Different roles for alpha 4-integrin/VCAM-1 and alpha 4/fibronectin interactions in allograft rejection.

Stegall MD, Elices M, Pietra W, Shepard G, Gup C, Gill RG.

Transplant Proc. 1999 Feb-Mar;31(1-2):786. No abstract available. PMID: 10083336 [PubMed - indexed for MEDLINE]Related articles

The 2C T-cell transgenic mouse: an in vivo model of allospecific cytotoxic T-cell activation and homing.

Stegall MD, Elices M, Shepard G, Gup C, Ninova D, Ferguson D, Gill RG.

Transplant Proc. 1999 Feb-Mar;31(1-2):779. No abstract available. PMID: 10083330 [PubMed - indexed for MEDLINE]Related articles

CD4 T cells acutely reject cardiac allografts via direct donor recognition.

Pietra B, Rizeq M, Bolwerk A, Gill RG.

Transplant Proc. 1999 Feb-Mar;31(1-2):92. No abstract available. PMID: 10083022 [PubMed - indexed for MEDLINE]Related articles

Tolerance to antigen-presenting cell-depleted islet allografts is CD4 T cell dependent.

Coulombe M, Yang H, Wolf LA, Gill RG.

J Immunol. 1999 Mar 1;162(5):2503-10.PMID: 10072489 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of deletion versus regulation in the maintenance of self-tolerance.

Gill RG.

Diabetes Metab Rev. 1997 Dec;13(4):309-14. Review. No abstract available. PMID: 9509281 [PubMed - indexed for MEDLINE]Related articles

Autoimmune islet damage mediated by insulin-specific T cells.

Crawford M, Daniel D, Wegmann D, Yang H, Gill RG.

Transplant Proc. 1997 Feb-Mar;29(1-2):758-9. No abstract available. PMID: 9123512 [PubMed - indexed for MEDLINE]Related articles

Adoptive transfer of CD4 T-cell dependent allograft tolerance.

Coulombe M, Yang H, Gill RG.

Transplant Proc. 1997 Feb-Mar;29(1-2):1166-7. No abstract available. PMID: 9123256 [PubMed - indexed for MEDLINE]Related articles