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    Results: 1 to 50 of 92

    1.

    Mapatumumab, a fully human agonistic monoclonal antibody that targets TRAIL-R1, in combination with gemcitabine and cisplatin: a phase I study.

    Mom CH, Verweij J, Oldenhuis CN, Gietema JA, Fox NL, Miceli R, Eskens FA, Loos WJ, de Vries EG, Sleijfer S.

    Clin Cancer Res. 2009 Sep 1;15(17):5584-90. Epub 2009 Aug 18.PMID: 19690193 [PubMed - in process]Related articles

    2.

    Prevalence of paraneoplastic hyperthyroidism in patients with metastatic non-seminomatous germ-cell tumors.

    Oosting SF, de Haas EC, Links TP, de Bruin D, Sluiter WJ, de Jong IJ, Hoekstra HJ, Sleijfer DT, Gietema JA.

    Ann Oncol. 2009 Jul 15. [Epub ahead of print]PMID: 19605510 [PubMed - as supplied by publisher]Related articles

    3.

    Evaluation of sub-acute changes in cardiac function after cisplatin-based combination chemotherapy for testicular cancer.

    Altena R, de Haas EC, Nuver J, Brouwer CA, van den Berg MP, Smit AJ, Postma A, Sleijfer DT, Gietema JA.

    Br J Cancer. 2009 Jun 16;100(12):1861-6. Epub 2009 May 19.PMID: 19455138 [PubMed - indexed for MEDLINE]Related articles

    4.

    Cardiovascular toxicity caused by cancer treatment: strategies for early detection.

    Altena R, Perik PJ, van Veldhuisen DJ, de Vries EG, Gietema JA.

    Lancet Oncol. 2009 Apr;10(4):391-9. Review.PMID: 19341970 [PubMed - indexed for MEDLINE]Related articles

    5.

    Insulin-like growth factors and insulin-like growth factor-binding proteins in relation to disease status and incidence of hypoglycaemia in patients with a gastrointestinal stromal tumour.

    Rikhof B, van Doorn J, Suurmeijer AJ, Rautenberg MW, Groenen PJ, Verdijk MA, Jager PL, de Jong S, Gietema JA, van der Graaf WT.

    Ann Oncol. 2009 Sep;20(9):1582-8. Epub 2009 Mar 10.PMID: 19276395 [PubMed - indexed for MEDLINE]Related articles

    6.

    Long-term morbidity of adjuvant whole abdominal radiotherapy (WART) or chemotherapy for early stage ovarian cancer.

    Engelen MJ, Snel BJ, Schaapveld M, Pras E, de Vries EG, Gietema JA, van der Zee AG, Willemse PH.

    Eur J Cancer. 2009 May;45(7):1193-200. Epub 2009 Feb 7.PMID: 19201598 [PubMed - indexed for MEDLINE]Related articles

    7.

    Clinical evaluation of M30 and M65 ELISA cell death assays as circulating biomarkers in a drug-sensitive tumor, testicular cancer.

    de Haas EC, di Pietro A, Simpson KL, Meijer C, Suurmeijer AJ, Lancashire LJ, Cummings J, de Jong S, de Vries EG, Dive C, Gietema JA.

    Neoplasia. 2008 Oct;10(10):1041-8.PMID: 18813353 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Low-dose anthracyclines in childhood Acute Lymphoblastic Leukemia (ALL): no cardiac deterioration more than 20 years post-treatment.

    Brouwer CA, Gietema JA, van den Berg MP, Bink-Boelkens MT, Elzenga NJ, Haaksma J, Kamps WA, Vonk JM, Postma A.

    J Cancer Surviv. 2007 Dec;1(4):255-60. Epub 2007 Sep 27.PMID: 18648960 [PubMed - indexed for MEDLINE]Related articles

    9.

    Weakness and numbness after chemotherapy for metastatic non-seminoma testis: a new neurological complication.

    Verdonk RC, Enting RH, Janmaat M, Schroder CP, Sleijfer DT, Gietema JA.

    Acta Oncol. 2008;47(8):1596-8. No abstract available. PMID: 18607855 [PubMed - indexed for MEDLINE]Related articles

    10.

    [Diagnostics and treatment of cholangiocarcinoma]

    Mantel HT, Verdonk RC, van Dullemen HM, Gietema JA, Slooff MJ, Porte RJ.

    Ned Tijdschr Geneeskd. 2008 May 3;152(18):1037-41. Review. Dutch. PMID: 18547024 [PubMed - indexed for MEDLINE]Related articles

    11.

    Semen quality in men with disseminated testicular cancer: relation with human chorionic gonadotropin beta-subunit and pituitary gonadal hormones.

    de Bruin D, de Jong IJ, Arts EG, Nuver J, Dullaart RP, Sluiter WJ, Hoekstra HJ, Sleijfer DT, Gietema JA.

    Fertil Steril. 2009 Jun;91(6):2481-6. Epub 2008 Apr 28.PMID: 18440530 [PubMed - indexed for MEDLINE]Related articles

    12.

    Variation in bleomycin hydrolase gene is associated with reduced survival after chemotherapy for testicular germ cell cancer.

    de Haas EC, Zwart N, Meijer C, Nuver J, Boezen HM, Suurmeijer AJ, Hoekstra HJ, van der Steege G, Sleijfer DT, Gietema JA.

    J Clin Oncol. 2008 Apr 10;26(11):1817-23.PMID: 18398146 [PubMed - indexed for MEDLINE]Related articles

    13.

    Prognostic versus predictive value of biomarkers in oncology.

    Oldenhuis CN, Oosting SF, Gietema JA, de Vries EG.

    Eur J Cancer. 2008 May;44(7):946-53. Epub 2008 Apr 7. Review.PMID: 18396036 [PubMed - indexed for MEDLINE]Related articles

    14.

    [Angiogenesis inhibitors for the systemic treatment of metastatic renal cell carcinoma: sunitinib, sorafenib, bevacizumab and temsirolimus]

    de Mulder PH, Haanen JB, Sleijfer S, Kruit WH, Gietema JA, Richel DJ, Groenewegen G, Voest EE, van den Eertwegh AJ, Osanto S, Jansen RL, Mulders PF.

    Ned Tijdschr Geneeskd. 2008 Feb 16;152(7):371-5. Review. Dutch. PMID: 18380383 [PubMed - indexed for MEDLINE]Related articles

    15.

    Cardiotoxicity associated with the use of trastuzumab in breast cancer patients.

    Perik PJ, de Korte MA, van Veldhuisen DJ, Gietema JA, Sleijfer DT, de Vries EG.

    Expert Rev Anticancer Ther. 2007 Dec;7(12):1763-71. Review.PMID: 18062750 [PubMed - indexed for MEDLINE]Related articles

    16.

    A phase I dose escalation study of BIBW 2992, an irreversible dual inhibitor of epidermal growth factor receptor 1 (EGFR) and 2 (HER2) tyrosine kinase in a 2-week on, 2-week off schedule in patients with advanced solid tumours.

    Eskens FA, Mom CH, Planting AS, Gietema JA, Amelsberg A, Huisman H, van Doorn L, Burger H, Stopfer P, Verweij J, de Vries EG.

    Br J Cancer. 2008 Jan 15;98(1):80-5. Epub 2007 Nov 20.PMID: 18026190 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Results of plasma N-terminal pro B-type natriuretic peptide and cardiac troponin monitoring in GIST patients do not support the existence of imatinib-induced cardiotoxicity.

    Perik PJ, Rikhof B, de Jong FA, Verweij J, Gietema JA, van der Graaf WT.

    Ann Oncol. 2008 Feb;19(2):359-61. Epub 2007 Oct 24.PMID: 17962203 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Treatment-specific risks of second malignancies and cardiovascular disease in 5-year survivors of testicular cancer.

    van den Belt-Dusebout AW, de Wit R, Gietema JA, Horenblas S, Louwman MW, Ribot JG, Hoekstra HJ, Ouwens GM, Aleman BM, van Leeuwen FE.

    J Clin Oncol. 2007 Oct 1;25(28):4370-8.PMID: 17906202 [PubMed - indexed for MEDLINE]Related articles

    19.

    111Indium-trastuzumab visualises myocardial human epidermal growth factor receptor 2 expression shortly after anthracycline treatment but not during heart failure: a clue to uncover the mechanisms of trastuzumab-related cardiotoxicity.

    de Korte MA, de Vries EG, Lub-de Hooge MN, Jager PL, Gietema JA, van der Graaf WT, Sluiter WJ, van Veldhuisen DJ, Suter TM, Sleijfer DT, Perik PJ.

    Eur J Cancer. 2007 Sep;43(14):2046-51. Epub 2007 Aug 24.PMID: 17719768 [PubMed - indexed for MEDLINE]Related articles

    20.

    Changes in body composition after childhood cancer treatment: impact on future health status--a review.

    Brouwer CA, Gietema JA, Kamps WA, de Vries EG, Postma A.

    Crit Rev Oncol Hematol. 2007 Jul;63(1):32-46. Epub 2007 Mar 6. Review.PMID: 17344062 [PubMed - indexed for MEDLINE]Related articles

    21.

    Granulosa cell tumors of the ovary: the clinical value of serum inhibin A and B levels in a large single center cohort.

    Mom CH, Engelen MJ, Willemse PH, Gietema JA, ten Hoor KA, de Vries EG, van der Zee AG.

    Gynecol Oncol. 2007 May;105(2):365-72. Epub 2007 Feb 15.PMID: 17306349 [PubMed - indexed for MEDLINE]Related articles

    22.

    Follow-up of successfully treated testicular cancer patients: consequences of the metabolic syndrome.

    de Haas EC, Sleijfer DT, Gietema JA.

    Ann Oncol. 2007 Feb;18(2):211-2. Epub 2007 Jan 17. No abstract available. PMID: 17229771 [PubMed - indexed for MEDLINE]Related articlesFree article

    23.

    The relation between soluble apoptotic proteins and subclinical cardiotoxicity in adjuvant-treated breast cancer patients.

    Perik PJ, De Vries EG, Boomsma F, Messerschmidt J, Van Veldhuisen DJ, Sleijfer DT, Gietema JA, Van der Graaf WT.

    Anticancer Res. 2006 Sep-Oct;26(5B):3803-11.PMID: 17094405 [PubMed - indexed for MEDLINE]Related articles

    24.

    The role of oral mucositis on the systemic inflammation parameter IL-8 in febrile neutropenic cancer patients.

    Stokman MA, Oude Nijhuis CS, Spijkervet FK, de Bont ES, Dijkstra PU, Daenen SM, Gietema JA, van der Graaf WT, Groen HJ, Vellenga E, Kamps WA.

    Cancer Invest. 2006 Aug-Sep;24(5):479-83.PMID: 16939955 [PubMed - indexed for MEDLINE]Related articles

    25.

    The clinical trail of TRAIL.

    Duiker EW, Mom CH, de Jong S, Willemse PH, Gietema JA, van der Zee AG, de Vries EG.

    Eur J Cancer. 2006 Sep;42(14):2233-40. Epub 2006 Aug 1. Review.PMID: 16884904 [PubMed - indexed for MEDLINE]Related articles

    26.

    Serum HER2 levels are increased in patients with chronic heart failure.

    Perik PJ, de Vries EG, Gietema JA, van der Graaf WT, Smilde TD, Sleijfer DT, van Veldhuisen DJ.

    Eur J Heart Fail. 2007 Feb;9(2):173-7. Epub 2006 Jul 24.PMID: 16860598 [PubMed - indexed for MEDLINE]Related articles

    27.

    Long-term cardiac follow-up in survivors of a malignant bone tumour.

    Brouwer CA, Gietema JA, van den Berg MP, Bink-Boelkens MT, Elzenga NJ, Haaksma J, Kamps WA, Vonk JM, de Vries EG, Postma A.

    Ann Oncol. 2006 Oct;17(10):1586-91. Epub 2006 Jul 20.PMID: 16857723 [PubMed - indexed for MEDLINE]Related articlesFree article

    28.

    A phase I study assessing the safety and pharmacokinetics of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 with gemcitabine and cisplatin in patients with solid tumors.

    Gietema JA, Hoekstra R, de Vos FY, Uges DR, van der Gaast A, Groen HJ, Loos WJ, Knight RA, Carr RA, Humerickhouse RA, Eskens FA.

    Ann Oncol. 2006 Aug;17(8):1320-7. Epub 2006 May 25.PMID: 16728485 [PubMed - indexed for MEDLINE]Related articlesFree article

    29.

    Indium-111-labeled trastuzumab scintigraphy in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer.

    Perik PJ, Lub-De Hooge MN, Gietema JA, van der Graaf WT, de Korte MA, Jonkman S, Kosterink JG, van Veldhuisen DJ, Sleijfer DT, Jager PL, de Vries EG.

    J Clin Oncol. 2006 May 20;24(15):2276-82.PMID: 16710024 [PubMed - indexed for MEDLINE]Related articles

    30.

    Tumor necrosis factor-related apoptosis-inducing ligand pathway and its therapeutic implications.

    de Vries EG, Gietema JA, de Jong S.

    Clin Cancer Res. 2006 Apr 15;12(8):2390-3. No abstract available. PMID: 16638843 [PubMed - indexed for MEDLINE]Related articlesFree article

    31.

    Phase I trial with BMS-275183, a novel oral taxane with promising antitumor activity.

    Bröker LE, de Vos FY, van Groeningen CJ, Kuenen BC, Gall HE, Woo MH, Voi M, Gietema JA, de Vries EG, Giaccone G.

    Clin Cancer Res. 2006 Mar 15;12(6):1760-7.PMID: 16551860 [PubMed - indexed for MEDLINE]Related articlesFree article

    32.

    Circulating apoptotic proteins are increased in long-term disease-free breast cancer survivors.

    Perik PJ, Van der Graaf WT, De Vries EG, Boomsma F, Messerschmidt J, Van Veldhuisen DJ, Sleijfer DT, Gietema JA.

    Acta Oncol. 2006;45(2):175-83.PMID: 16546863 [PubMed - indexed for MEDLINE]Related articles

    33.

    Long-term risk of cardiovascular disease in 5-year survivors of testicular cancer.

    van den Belt-Dusebout AW, Nuver J, de Wit R, Gietema JA, ten Bokkel Huinink WW, Rodrigus PT, Schimmel EC, Aleman BM, van Leeuwen FE.

    J Clin Oncol. 2006 Jan 20;24(3):467-75.PMID: 16421423 [PubMed - indexed for MEDLINE]Related articles

    34.

    Phase I study of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 with 5-fluorouracil and leucovorin: a safe combination.

    Hoekstra R, de Vos FY, Eskens FA, de Vries EG, Uges DR, Knight R, Carr RA, Humerickhouse R, Verweij J, Gietema JA.

    Eur J Cancer. 2006 Mar;42(4):467-72. Epub 2006 Jan 10.PMID: 16406507 [PubMed - indexed for MEDLINE]Related articles

    35.

    In vitro hypoxia-conditioned colon cancer cell lines derived from HCT116 and HT29 exhibit altered apoptosis susceptibility and a more angiogenic profile in vivo.

    Yao K, Gietema JA, Shida S, Selvakumaran M, Fonrose X, Haas NB, Testa J, O'Dwyer PJ.

    Br J Cancer. 2005 Dec 12;93(12):1356-63.PMID: 16333244 [PubMed - indexed for MEDLINE]Related articlesFree article

    36.

    Acute chemotherapy-induced cardiovascular changes in patients with testicular cancer.

    Nuver J, Smit AJ, van der Meer J, van den Berg MP, van der Graaf WT, Meinardi MT, Sleijfer DT, Hoekstra HJ, van Gessel AI, van Roon AM, Gietema JA.

    J Clin Oncol. 2005 Dec 20;23(36):9130-7. Epub 2005 Nov 21.PMID: 16301596 [PubMed - indexed for MEDLINE]Related articles

    37.

    Feasibility of withholding antibiotics in selected febrile neutropenic cancer patients.

    Oude Nijhuis C, Kamps WA, Daenen SM, Gietema JA, van der Graaf WT, Groen HJ, Vellenga E, Ten Vergert EM, Vermeulen KM, de Vries-Hospers HG, de Bont ES.

    J Clin Oncol. 2005 Oct 20;23(30):7437-44.PMID: 16234511 [PubMed - indexed for MEDLINE]Related articles

    38.

    Use of natriuretic peptides for detecting cardiac dysfunction in long-term disease-free breast cancer survivors.

    Perik PJ, De Vries EG, Boomsma F, van der Graaf WT, Sleijfer DT, van Veldhuisen DJ, Gietema JA.

    Anticancer Res. 2005 Sep-Oct;25(5):3651-7.PMID: 16101196 [PubMed - indexed for MEDLINE]Related articles

    39.

    Testicular germ cell tumours: the paradigm of chemo-sensitive solid tumours.

    di Pietro A, Vries EG, Gietema JA, Spierings DC, de Jong S.

    Int J Biochem Cell Biol. 2005 Dec;37(12):2437-56. Epub 2005 Aug 11. Review.PMID: 16099193 [PubMed - indexed for MEDLINE]Related articles

    40.

    Phase I safety, pharmacokinetic, and pharmacodynamic study of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 in patients with advanced cancer.

    Hoekstra R, de Vos FY, Eskens FA, Gietema JA, van der Gaast A, Groen HJ, Knight RA, Carr RA, Humerickhouse RA, Verweij J, de Vries EG.

    J Clin Oncol. 2005 Aug 1;23(22):5188-97.PMID: 16051960 [PubMed - indexed for MEDLINE]Related articles

    41.

    Natriuretic peptides in anthracycline-induced cardiotoxicity.

    Perik PJ, van Veldhuisen DJ, Gietema JA.

    Eur J Heart Fail. 2005 Aug;7(5):940-1; author reply 941. No abstract available. PMID: 16048743 [PubMed - indexed for MEDLINE]Related articles

    42.

    Genetic variation in the bleomycin hydrolase gene and bleomycin-induced pulmonary toxicity in germ cell cancer patients.

    Nuver J, Lutke Holzik MF, van Zweeden M, Hoekstra HJ, Meijer C, Suurmeijer AJ, Groen HJ, Hofstra RM, Sluiter WJ, Groen H, Sleijfer DT, Gietema JA.

    Pharmacogenet Genomics. 2005 Jun;15(6):399-405.PMID: 15900213 [PubMed - indexed for MEDLINE]Related articles

    43.

    The metabolic syndrome and disturbances in hormone levels in long-term survivors of disseminated testicular cancer.

    Nuver J, Smit AJ, Wolffenbuttel BH, Sluiter WJ, Hoekstra HJ, Sleijfer DT, Gietema JA.

    J Clin Oncol. 2005 Jun 1;23(16):3718-25. Epub 2005 Feb 28.PMID: 15738540 [PubMed - indexed for MEDLINE]Related articles

    44.

    A phase I study of intraperitoneal topotecan in combination with intravenous carboplatin and paclitaxel in advanced ovarian cancer.

    Bos AM, De Vos FY, de Vries EG, Beijnen JH, Rosing H, Mourits MJ, van der Zee AG, Gietema JA, Willemse PH.

    Eur J Cancer. 2005 Mar;41(4):539-48. Epub 2005 Jan 11.PMID: 15737558 [PubMed - indexed for MEDLINE]Related articles

    45.

    Left ventricular and cardiac autonomic function in survivors of testicular cancer.

    Nuver J, Smit AJ, Sleijfer DT, van Gessel AI, van Roon AM, van der Meer J, van den Berg MP, Hoekstra HJ, Sluiter WJ, Gietema JA.

    Eur J Clin Invest. 2005 Feb;35(2):99-103.PMID: 15667580 [PubMed - indexed for MEDLINE]Related articles

    46.

    The dilemma of the strive for apoptosis in oncology: mind the heart.

    Perik PJ, de Vries EG, Gietema JA, van der Graaf WT, Sleijfer DT, Suurmeijer AJ, van Veldhuisen DJ.

    Crit Rev Oncol Hematol. 2005 Feb;53(2):101-13. Review.PMID: 15661561 [PubMed - indexed for MEDLINE]Related articles

    47.

    Endothelial cell effects of cytotoxics: balance between desired and unwanted effects.

    de Vos FY, Willemse PH, de Vries EG, Gietema JA.

    Cancer Treat Rev. 2004 Oct;30(6):495-513. Review.PMID: 15325031 [PubMed - indexed for MEDLINE]Related articles

    48.

    Placental site trophoblastic tumor in a late recurrence of a nonseminomatous germ cell tumor of the testis.

    Suurmeijer AJ, Gietema JA, Hoekstra HJ.

    Am J Surg Pathol. 2004 Jun;28(6):830-3.PMID: 15166678 [PubMed - indexed for MEDLINE]Related articles

    49.

    A phase I study with MAG-camptothecin intravenously administered weekly for 3 weeks in a 4-week cycle in adult patients with solid tumours.

    Wachters FM, Groen HJ, Maring JG, Gietema JA, Porro M, Dumez H, de Vries EG, van Oosterom AT.

    Br J Cancer. 2004 Jun 14;90(12):2261-7.PMID: 15150611 [PubMed - indexed for MEDLINE]Related articlesFree article

    50.

    Imatinib mesylate for the treatment of gastrointestinal stromal tumours: best monitored with FDG PET.

    Jager PL, Gietema JA, van der Graaf WT.

    Nucl Med Commun. 2004 May;25(5):433-8.PMID: 15100500 [PubMed - indexed for MEDLINE]Related articles

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