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    Results: 16

    1.

    A Point Mutation in Sec61{alpha}1 Leads to Diabetes and Hepatosteatosis in Mice.

    Lloyd DJ, Wheeler MC, Gekakis N.

    Diabetes. 2009 Nov 23. [Epub ahead of print]PMID: 19934005 [PubMed - as supplied by publisher]

    2.

    Negative regulators of insulin signaling revealed in a genome-wide functional screen.

    Huang SM, Hancock MK, Pitman JL, Orth AP, Gekakis N.

    PLoS One. 2009 Sep 3;4(9):e6871.PMID: 19727444 [PubMed - in process]Related articlesFree article

    3.

    Loss-of-function mutation in myostatin reduces tumor necrosis factor alpha production and protects liver against obesity-induced insulin resistance.

    Wilkes JJ, Lloyd DJ, Gekakis N.

    Diabetes. 2009 May;58(5):1133-43. Epub 2009 Feb 10.PMID: 19208906 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    CIPC is a mammalian circadian clock protein without invertebrate homologues.

    Zhao WN, Malinin N, Yang FC, Staknis D, Gekakis N, Maier B, Reischl S, Kramer A, Weitz CJ.

    Nat Cell Biol. 2007 Mar;9(3):268-75. Epub 2007 Feb 18.PMID: 17310242 [PubMed - indexed for MEDLINE]Related articles

    5.

    A role for Alström syndrome protein, alms1, in kidney ciliogenesis and cellular quiescence.

    Li G, Vega R, Nelms K, Gekakis N, Goodnow C, McNamara P, Wu H, Hong NA, Glynne R.

    PLoS Genet. 2007 Jan 5;3(1):e8. Epub 2006 Nov 30.PMID: 17206865 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Obesity, hyperphagia and increased metabolic efficiency in Pc1 mutant mice.

    Lloyd DJ, Bohan S, Gekakis N.

    Hum Mol Genet. 2006 Jun 1;15(11):1884-93. Epub 2006 Apr 27. Erratum in: Hum Mol Genet. 2008 Nov 1;17(21):3435. PMID: 16644867 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Diabetes insipidus in mice with a mutation in aquaporin-2.

    Lloyd DJ, Hall FW, Tarantino LM, Gekakis N.

    PLoS Genet. 2005 Aug;1(2):e20. Epub 2005 Aug 19.PMID: 16121255 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Ubiquitin signals protein trafficking via interaction with a novel ubiquitin binding domain in the membrane fusion regulator, Vps9p.

    Donaldson KM, Yin H, Gekakis N, Supek F, Joazeiro CA.

    Curr Biol. 2003 Feb 4;13(3):258-62.PMID: 12573224 [PubMed - indexed for MEDLINE]Related articles

    9.

    Mammalian circadian autoregulatory loop: a timeless ortholog and mPer1 interact and negatively regulate CLOCK-BMAL1-induced transcription.

    Sangoram AM, Saez L, Antoch MP, Gekakis N, Staknis D, Whiteley A, Fruechte EM, Vitaterna MH, Shimomura K, King DP, Young MW, Weitz CJ, Takahashi JS.

    Neuron. 1998 Nov;21(5):1101-13.PMID: 9856465 [PubMed - indexed for MEDLINE]Related articles

    10.

    Closing the circadian loop: CLOCK-induced transcription of its own inhibitors per and tim.

    Darlington TK, Wager-Smith K, Ceriani MF, Staknis D, Gekakis N, Steeves TD, Weitz CJ, Takahashi JS, Kay SA.

    Science. 1998 Jun 5;280(5369):1599-603.PMID: 9616122 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Role of the CLOCK protein in the mammalian circadian mechanism.

    Gekakis N, Staknis D, Nguyen HB, Davis FC, Wilsbacher LD, King DP, Takahashi JS, Weitz CJ.

    Science. 1998 Jun 5;280(5369):1564-9.PMID: 9616112 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Isolation of timeless by PER protein interaction: defective interaction between timeless protein and long-period mutant PERL.

    Gekakis N, Saez L, Delahaye-Brown AM, Myers MP, Sehgal A, Young MW, Weitz CJ.

    Science. 1995 Nov 3;270(5237):811-5.PMID: 7481773 [PubMed - indexed for MEDLINE]Related articles

    13.

    Control of the murine phosphofructokinase-A gene during muscle differentiation.

    Gekakis N, Sul HS.

    Biochemistry. 1994 Feb 22;33(7):1771-7.PMID: 8110779 [PubMed - indexed for MEDLINE]Related articles

    14.

    Structure, distribution, and functional expression of the phosphofructokinase C isozyme.

    Gekakis N, Johnson RC, Jerkins A, Mains RE, Sul HS.

    J Biol Chem. 1994 Feb 4;269(5):3348-55.PMID: 8106374 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Phosphofructokinase isozyme expression during myoblast differentiation.

    Gekakis N, Gehnrich SC, Sul HS.

    J Biol Chem. 1989 Mar 5;264(7):3658-61.PMID: 2521854 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Liver (B-type) phosphofructokinase mRNA. Cloning, structure, and expression.

    Gehnrich SC, Gekakis N, Sul HS.

    J Biol Chem. 1988 Aug 25;263(24):11755-9.PMID: 2969893 [PubMed - indexed for MEDLINE]Related articlesFree article

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