PubMed

Suppression of diacylglycerol acyltransferase-2 (DGAT2), but not DGAT1, with antisense oligonucleotides reverses diet-induced hepatic steatosis and insulin resistance.

Choi CS, Savage DB, Kulkarni A, Yu XX, Liu ZX, Morino K, Kim S, Distefano A, Samuel VT, Neschen S, Zhang D, Wang A, Zhang XM, Kahn M, Cline GW, Pandey SK, Geisler JG, Bhanot S, Monia BP, Shulman GI.

J Biol Chem. 2007 Aug 3;282(31):22678-88. Epub 2007 May 27.PMID: 17526931 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of protein kinase Cepsilon prevents hepatic insulin resistance in nonalcoholic fatty liver disease.

Samuel VT, Liu ZX, Wang A, Beddow SA, Geisler JG, Kahn M, Zhang XM, Monia BP, Bhanot S, Shulman GI.

J Clin Invest. 2007 Mar;117(3):739-45. Epub 2007 Feb 22.PMID: 17318260 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeting foxo1 in mice using antisense oligonucleotide improves hepatic and peripheral insulin action.

Samuel VT, Choi CS, Phillips TG, Romanelli AJ, Geisler JG, Bhanot S, McKay R, Monia B, Shutter JR, Lindberg RA, Shulman GI, Veniant MM.

Diabetes. 2006 Jul;55(7):2042-50.PMID: 16804074 [PubMed - indexed for MEDLINE]Related articlesFree article

Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2.

Savage DB, Choi CS, Samuel VT, Liu ZX, Zhang D, Wang A, Zhang XM, Cline GW, Yu XX, Geisler JG, Bhanot S, Monia BP, Shulman GI.

J Clin Invest. 2006 Mar;116(3):817-24. Epub 2006 Feb 16.PMID: 16485039 [PubMed - indexed for MEDLINE]Related articlesFree article

Estrogen can prevent or reverse obesity and diabetes in mice expressing human islet amyloid polypeptide.

Geisler JG, Zawalich W, Zawalich K, Lakey JR, Stukenbrok H, Milici AJ, Soeller WC.

Diabetes. 2002 Jul;51(7):2158-69.PMID: 12086946 [PubMed - indexed for MEDLINE]Related articlesFree article

Nspl1, a new Z-band-associated protein.

Geisler JG, Palmer RJ, Stubbs LJ, Mucenski ML.

J Muscle Res Cell Motil. 1999 Oct;20(7):661-8.PMID: 10672514 [PubMed - indexed for MEDLINE]Related articles

Molecular cloning of a novel mouse gene with predominant muscle and neural expression.

Geisler JG, Stubbs LJ, Wasserman WW, Mucenski ML.

Mamm Genome. 1998 Apr;9(4):274-82.PMID: 9530622 [PubMed - indexed for MEDLINE]Related articles

Ectopic expression of the agouti gene in transgenic mice causes obesity, features of type II diabetes, and yellow fur.

Klebig ML, Wilkinson JE, Geisler JG, Woychik RP.

Proc Natl Acad Sci U S A. 1995 May 23;92(11):4728-32.PMID: 7761391 [PubMed - indexed for MEDLINE]Related articlesFree article