PubMed

Advanced glycation of the Arg-Gly-Asp (RGD) tripeptide motif modulates retinal microvascular endothelial cell dysfunction.

McDonald DM, Coleman G, Bhatwadekar A, Gardiner TA, Stitt AW.

Mol Vis. 2009 Aug 5;15:1509-20.PMID: 19668595 [PubMed - indexed for MEDLINE]Related articlesFree article

Persistent measles virus infection of mouse neural cells lacking known human entry receptors.

Abdullah H, Earle JA, Gardiner TA, Tangy F, Cosby SL.

Neuropathol Appl Neurobiol. 2009 Oct;35(5):473-86.PMID: 19490430 [PubMed - indexed for MEDLINE]Related articles

Retinal endothelial cell apoptosis stimulates recruitment of endothelial progenitor cells.

Bhatwadekar AD, Glenn JV, Curtis TM, Grant MB, Stitt AW, Gardiner TA.

Invest Ophthalmol Vis Sci. 2009 Oct;50(10):4967-73. Epub 2009 May 27.PMID: 19474402 [PubMed - indexed for MEDLINE]Related articles

Microvascular lesions of diabetic retinopathy: clues towards understanding pathogenesis?

Curtis TM, Gardiner TA, Stitt AW.

Eye (Lond). 2009 Jul;23(7):1496-508. Epub 2009 May 15.PMID: 19444297 [PubMed - in process]Related articles

Investigation of pericytes, hypoxia, and vascularity in bladder tumors: association with clinical outcomes.

O'Keeffe MB, Devlin AH, Burns AJ, Gardiner TA, Logan ID, Hirst DG, McKeown SR.

Oncol Res. 2008;17(3):93-101.PMID: 18669161 [PubMed - indexed for MEDLINE]Related articles

The pleiotropic effects of simvastatin on retinal microvascular endothelium has important implications for ischaemic retinopathies.

Medina RJ, O'Neill CL, Devine AB, Gardiner TA, Stitt AW.

PLoS One. 2008 Jul 9;3(7):e2584.PMID: 18612412 [PubMed - indexed for MEDLINE]Related articlesFree article

Evaluation of N (epsilon)-(3-formyl-3,4-dehydropiperidino)lysine as a novel biomarker for the severity of diabetic retinopathy.

Zhang X, Lai Y, McCance DR, Uchida K, McDonald DM, Gardiner TA, Stitt AW, Curtis TM.

Diabetologia. 2008 Sep;51(9):1723-30. Epub 2008 Jun 28.PMID: 18587559 [PubMed - indexed for MEDLINE]Related articles

Advanced glycation of fibronectin impairs vascular repair by endothelial progenitor cells: implications for vasodegeneration in diabetic retinopathy.

Bhatwadekar AD, Glenn JV, Li G, Curtis TM, Gardiner TA, Stitt AW.

Invest Ophthalmol Vis Sci. 2008 Mar;49(3):1232-41.PMID: 18326753 [PubMed - indexed for MEDLINE]Related articlesFree article

A new advanced glycation inhibitor, LR-90, prevents experimental diabetic retinopathy in rats.

Bhatwadekar A, Glenn JV, Figarola JL, Scott S, Gardiner TA, Rahbar S, Stitt AW.

Br J Ophthalmol. 2008 Apr;92(4):545-7. Epub 2008 Jan 22.PMID: 18211931 [PubMed - indexed for MEDLINE]Related articles

Inhibition of advanced glycation and absence of galectin-3 prevent blood-retinal barrier dysfunction during short-term diabetes.

Canning P, Glenn JV, Hsu DK, Liu FT, Gardiner TA, Stitt AW.

Exp Diabetes Res. 2007;2007:51837.PMID: 17641742 [PubMed - indexed for MEDLINE]Related articlesFree article

Arteriolar involvement in the microvascular lesions of diabetic retinopathy: implications for pathogenesis.

Gardiner TA, Archer DB, Curtis TM, Stitt AW.

Microcirculation. 2007 Jan;14(1):25-38. Review.PMID: 17365659 [PubMed - indexed for MEDLINE]Related articles

Kit-positive interstitial cells in the rabbit urethra: structural relationships with nerves and smooth muscle.

Lyons AD, Gardiner TA, McCloskey KD.

BJU Int. 2007 Mar;99(3):687-94. Epub 2006 Dec 20.PMID: 17212607 [PubMed - indexed for MEDLINE]Related articles

Involvement of MAPKs in endostatin-mediated regulation of blood-retinal barrier function.

Campbell M, Collery R, McEvoy A, Gardiner TA, Stitt AW, Brankin B.

Curr Eye Res. 2006 Dec;31(12):1033-45.PMID: 17169842 [PubMed - indexed for MEDLINE]Related articles

Retinopathy is reduced during experimental diabetes in a mouse model of outer retinal degeneration.

de Gooyer TE, Stevenson KA, Humphries P, Simpson DA, Gardiner TA, Stitt AW.

Invest Ophthalmol Vis Sci. 2006 Dec;47(12):5561-8.PMID: 17122149 [PubMed - indexed for MEDLINE]Related articlesFree article

Rod photoreceptor loss in Rho-/- mice reduces retinal hypoxia and hypoxia-regulated gene expression.

de Gooyer TE, Stevenson KA, Humphries P, Simpson DA, Curtis TM, Gardiner TA, Stitt AW.

Invest Ophthalmol Vis Sci. 2006 Dec;47(12):5553-60.PMID: 17122148 [PubMed - indexed for MEDLINE]Related articlesFree article

Kv1.5 is a major component underlying the A-type potassium current in retinal arteriolar smooth muscle.

McGahon MK, Dawicki JM, Arora A, Simpson DA, Gardiner TA, Stitt AW, Scholfield CN, McGeown JG, Curtis TM.

Am J Physiol Heart Circ Physiol. 2007 Feb;292(2):H1001-8. Epub 2006 Oct 13.PMID: 17040965 [PubMed - indexed for MEDLINE]Related articlesFree article

Recombinant alpha2(IV)NC1 domain of type IV collagen is an effective regulator of retinal capillary endothelial cell proliferation and inhibits pre-retinal neovascularisation.

Coleman G, Gardiner TA, Boutaud A, Stitt AW.

Graefes Arch Clin Exp Ophthalmol. 2007 Apr;245(4):581-7. Epub 2006 Aug 17.PMID: 16915401 [PubMed - indexed for MEDLINE]Related articles

VEGF165b, an endogenous C-terminal splice variant of VEGF, inhibits retinal neovascularization in mice.

Konopatskaya O, Churchill AJ, Harper SJ, Bates DO, Gardiner TA.

Mol Vis. 2006 May 26;12:626-32.PMID: 16735996 [PubMed - indexed for MEDLINE]Related articlesFree article

Endostatin modulates VEGF-mediated barrier dysfunction in the retinal microvascular endothelium.

Brankin B, Campbell M, Canning P, Gardiner TA, Stitt AW.

Exp Eye Res. 2005 Jul;81(1):22-31.PMID: 15978251 [PubMed - indexed for MEDLINE]Related articles

Impaired retinal angiogenesis in diabetes: role of advanced glycation end products and galectin-3.

Stitt AW, McGoldrick C, Rice-McCaldin A, McCance DR, Glenn JV, Hsu DK, Liu FT, Thorpe SR, Gardiner TA.

Diabetes. 2005 Mar;54(3):785-94.PMID: 15734857 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of tumor necrosis factor-alpha improves physiological angiogenesis and reduces pathological neovascularization in ischemic retinopathy.

Gardiner TA, Gibson DS, de Gooyer TE, de la Cruz VF, McDonald DM, Stitt AW.

Am J Pathol. 2005 Feb;166(2):637-44.PMID: 15681845 [PubMed - indexed for MEDLINE]Related articlesFree article

Advanced glycation endproduct modified basement membrane attenuates endothelin-1 induced [Ca2+]i signalling and contraction in retinal microvascular pericytes.

Hughes SJ, Wall N, Scholfield CN, McGeown JG, Gardiner TA, Stitt AW, Curtis TM.

Mol Vis. 2004 Dec 27;10:996-1004.PMID: 15635291 [PubMed - indexed for MEDLINE]Related articlesFree article

Substrates modified by advanced glycation end-products cause dysfunction and death in retinal pericytes by reducing survival signals mediated by platelet-derived growth factor.

Stitt AW, Hughes SJ, Canning P, Lynch O, Cox O, Frizzell N, Thorpe SR, Cotter TG, Curtis TM, Gardiner TA.

Diabetologia. 2004 Oct;47(10):1735-46. Epub 2004 Oct 22.PMID: 15502926 [PubMed - indexed for MEDLINE]Related articles

Chloroquine causes lysosomal dysfunction in neural retina and RPE: implications for retinopathy.

Mahon GJ, Anderson HR, Gardiner TA, McFarlane S, Archer DB, Stitt AW.

Curr Eye Res. 2004 Apr;28(4):277-84.PMID: 15259297 [PubMed - indexed for MEDLINE]Related articles

Ocular wounding prevents pre-retinal neovascularization and upregulates PEDF expression in the inner retina.

Stitt AW, Graham D, Gardiner TA.

Mol Vis. 2004 Jun 28;10:432-8.PMID: 15235573 [PubMed - indexed for MEDLINE]Related articlesFree article

Sources of PDGF expression in murine retina and the effect of short-term diabetes.

Cox OT, Simpson DA, Stitt AW, Gardiner TA.

Mol Vis. 2003 Dec 10;9:665-72.PMID: 14685146 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of advanced glycation end-products protects against retinal capillary basement membrane expansion during long-term diabetes.

Gardiner TA, Anderson HR, Stitt AW.

J Pathol. 2003 Oct;201(2):328-33.PMID: 14517851 [PubMed - indexed for MEDLINE]Related articles

The role of advanced glycation end products in retinal microvascular leukostasis.

Moore TC, Moore JE, Kaji Y, Frizzell N, Usui T, Poulaki V, Campbell IL, Stitt AW, Gardiner TA, Archer DB, Adamis AP.

Invest Ophthalmol Vis Sci. 2003 Oct;44(10):4457-64.PMID: 14507893 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevention of retinal capillary basement membrane thickening in diabetic dogs by a non-steroidal anti-inflammatory drug.

Gardiner TA, Anderson HR, Degenhardt T, Thorpe SR, Baynes JW, Archer DB, Stitt AW.

Diabetologia. 2003 Sep;46(9):1269-75. Epub 2003 Jul 12.PMID: 12861449 [PubMed - indexed for MEDLINE]Related articles

Characterisation of WE-14 in porcine ocular tissue.

Curry WJ, McCollum AP, Brockbank S, Gardiner TA, Maule AG, Stitt AW.

Regul Pept. 2003 May 15;113(1-3):41-7.PMID: 12686459 [PubMed - indexed for MEDLINE]Related articles

Role of vascular endothelial growth factor and placental growth factors during retinal vascular development and hyaloid regression.

Feeney SA, Simpson DA, Gardiner TA, Boyle C, Jamison P, Stitt AW.

Invest Ophthalmol Vis Sci. 2003 Feb;44(2):839-47.PMID: 12556420 [PubMed - indexed for MEDLINE]Related articlesFree article

The AGE inhibitor pyridoxamine inhibits development of retinopathy in experimental diabetes.

Stitt A, Gardiner TA, Alderson NL, Canning P, Frizzell N, Duffy N, Boyle C, Januszewski AS, Chachich M, Baynes JW, Thorpe SR.

Diabetes. 2002 Sep;51(9):2826-32. Erratum in: Diabetes 2003 Jan;52(1):223. Anderson Nathan L [corrected to Alderson Nathan L]. PMID: 12196477 [PubMed - indexed for MEDLINE]Related articlesFree article

Anti-angiogenic therapy for uveal melanoma--more haste, less speed.

Stitt AW, Gardiner TA.

Br J Ophthalmol. 2002 Apr;86(4):368-9. No abstract available. PMID: 11914199 [PubMed - indexed for MEDLINE]Related articlesFree article

Nerve pathology in the type 1 diabetic dog: effects of treatment with sulindac.

Walker D, Siddique I, Anderson H, Gardiner TA, Archer DB, Boulton AJM, Malik RA.

J Peripher Nerv Syst. 2001 Dec;6(4):219-26.PMID: 11800045 [PubMed - indexed for MEDLINE]Related articles

Synthetic peptides interacting with the 67-kd laminin receptor can reduce retinal ischemia and inhibit hypoxia-induced retinal neovascularization.

Gebarowska D, Stitt AW, Gardiner TA, Harriott P, Greer B, Nelson J.

Am J Pathol. 2002 Jan;160(1):307-13.PMID: 11786424 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of the 67 kDa laminin receptor (67LR) during retinal development: correlations with angiogenesis.

McKenna DJ, Simpson DA, Feeney S, Gardiner TA, Boyle C, Nelson J, Stitt AW.

Exp Eye Res. 2001 Jul;73(1):81-92.PMID: 11428865 [PubMed - indexed for MEDLINE]Related articles

Advanced glycation end products induce blood-retinal barrier dysfunction in normoglycemic rats.

Stitt AW, Bhaduri T, McMullen CB, Gardiner TA, Archer DB.

Mol Cell Biol Res Commun. 2000 Jun;3(6):380-8.PMID: 11032761 [PubMed - indexed for MEDLINE]Related articles

Expression of the VEGF gene family during retinal vaso-obliteration and hypoxia.

Simpson DA, Murphy GM, Bhaduri T, Gardiner TA, Archer DB, Stitt AW.

Biochem Biophys Res Commun. 1999 Aug 27;262(2):333-40.PMID: 10462475 [PubMed - indexed for MEDLINE]Related articles

Polyamine system in developing rat eye and an animal model of retinopathy of prematurity.

Gralek M, Sasiak K, Wojcik A, Gardiner TA, Fogel WA.

Graefes Arch Clin Exp Ophthalmol. 1999 Sep;237(9):781-6.PMID: 10447655 [PubMed - indexed for MEDLINE]Related articles

Endothelium-derived agents in pericyte function/dysfunction.

Chakravarthy U, Gardiner TA.

Prog Retin Eye Res. 1999 Jul;18(4):511-27. Review.PMID: 10217481 [PubMed - indexed for MEDLINE]Related articles

Expression of vascular endothelial growth factor (VEGF) and its receptors is regulated in eyes with intra-ocular tumours.

Stitt AW, Simpson DA, Boocock C, Gardiner TA, Murphy GM, Archer DB.

J Pathol. 1998 Nov;186(3):306-12.PMID: 10211121 [PubMed - indexed for MEDLINE]Related articles

The 67-kd laminin receptor is preferentially expressed by proliferating retinal vessels in a murine model of ischemic retinopathy.

Stitt AW, McKenna D, Simpson DA, Gardiner TA, Harriott P, Archer DB, Nelson J.

Am J Pathol. 1998 May;152(5):1359-65.PMID: 9588904 [PubMed - indexed for MEDLINE]Related articlesFree article

Advanced glycation end products (AGEs) co-localize with AGE receptors in the retinal vasculature of diabetic and of AGE-infused rats.

Stitt AW, Li YM, Gardiner TA, Bucala R, Archer DB, Vlassara H.

Am J Pathol. 1997 Feb;150(2):523-31.PMID: 9033268 [PubMed - indexed for MEDLINE]Related articlesFree article

Retinal and choroidal response to panretinal photocoagulation and ultrastructural perspective.

Stitt AW, Gardiner TA, Archer DB.

Graefes Arch Clin Exp Ophthalmol. 1996 May;234(5):349. No abstract available. PMID: 8740258 [PubMed - indexed for MEDLINE]Related articles

Endothelin-like immunoreactivity and receptor binding in the choroid and retina.

Stitt AW, Chakravarthy U, Gardiner TA, Archer DB.

Curr Eye Res. 1996 Jan;15(1):111-7.PMID: 8631198 [PubMed - indexed for MEDLINE]Related articles

Diabetic retinopathy: morphometric analysis of basement membrane thickening of capillaries in different retinal layers within arterial and venous environments.

Anderson HR, Stitt AW, Gardiner TA, Archer DB.

Br J Ophthalmol. 1995 Dec;79(12):1120-3.PMID: 8562548 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased endocytosis in retinal vascular endothelial cells grown in high glucose medium is modulated by inhibitors of nonenzymatic glycosylation.

Stitt AW, Chakravarthy U, Archer DB, Gardiner TA.

Diabetologia. 1995 Nov;38(11):1271-5.PMID: 8582535 [PubMed - indexed for MEDLINE]Related articles

Retinal and choroidal responses to panretinal photocoagulation: an ultrastructural perspective.

Stitt AW, Gardiner TA, Archer DB.

Graefes Arch Clin Exp Ophthalmol. 1995 Nov;233(11):699-705.PMID: 8566826 [PubMed - indexed for MEDLINE]Related articles

Histological and ultrastructural investigation of retinal microaneurysm development in diabetic patients.

Stitt AW, Gardiner TA, Archer DB.

Br J Ophthalmol. 1995 Apr;79(4):362-7.PMID: 7742285 [PubMed - indexed for MEDLINE]Related articlesFree article

Retinal vascular endothelial cell endocytosis increases in early diabetes.

Gardiner TA, Stitt AW, Archer DB.

Lab Invest. 1995 Apr;72(4):439-44.PMID: 7723283 [PubMed - indexed for MEDLINE]Related articles