PubMed

European population genetic substructure: further definition of ancestry informative markers for distinguishing among diverse European ethnic groups.

Tian C, Kosoy R, Nassir R, Lee A, Villoslada P, Klareskog L, Hammarström L, Garchon HJ, Pulver AE, Ransom M, Gregersen PK, Seldin MF.

Mol Med. 2009 Nov-Dec;15(11-12):371-83. Epub 2009 Aug 27.PMID: 19707526 [PubMed - in process]Related articlesFree article

Comprehensive linkage and association analyses identify haplotype, near to the TNFSF15 gene, significantly associated with spondyloarthritis.

Zinovieva E, Bourgain C, Kadi A, Letourneur F, Izac B, Said-Nahal R, Lebrun N, Cagnard N, Vigier A, Jacques S, Miceli-Richard C, Garchon HJ, Heath S, Charon C, Bacq D, Boland A, Zelenika D, Chiocchia G, Breban M.

PLoS Genet. 2009 Jun;5(6):e1000528. Epub 2009 Jun 19.PMID: 19543369 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of HLA-A in autoimmune myasthenia gravis with thymoma.

Vandiedonck C, Raffoux C, Eymard B, Tranchant C, Dulmet E, Krumeich S, Gajdos P, Garchon HJ.

J Neuroimmunol. 2009 May 29;210(1-2):120-3. Epub 2009 Mar 10.PMID: 19278738 [PubMed - indexed for MEDLINE]Related articles

Genetic factors in autoimmune myasthenia gravis.

Giraud M, Vandiedonck C, Garchon HJ.

Ann N Y Acad Sci. 2008;1132:180-92.PMID: 18567868 [PubMed - indexed for MEDLINE]Related articles

Polymorphic markers of the fibrillin-1 gene and systemic sclerosis in European Caucasian patients.

Wipff J, Giraud M, Sibilia J, Mouthon L, Meyer O, Tiev K, Airo P, Caramaschi P, Guiducci S, Garchon HJ, Matucci-Cerinic M, Kahan A, Avouac J, Boileau C, Allanore Y.

J Rheumatol. 2008 Apr;35(4):643-9. Epub 2008 Feb 15.PMID: 18278837 [PubMed - indexed for MEDLINE]Related articles

An IRF8-binding promoter variant and AIRE control CHRNA1 promiscuous expression in thymus.

Giraud M, Taubert R, Vandiedonck C, Ke X, Lévi-Strauss M, Pagani F, Baralle FE, Eymard B, Tranchant C, Gajdos P, Vincent A, Willcox N, Beeson D, Kyewski B, Garchon HJ.

Nature. 2007 Aug 23;448(7156):934-7. Epub 2007 Aug 8.PMID: 17687331 [PubMed - indexed for MEDLINE]Related articles

Genetic and functional analysis of the Nkt1 locus using congenic NOD mice: improved Valpha14-NKT cell performance but failure to protect against type 1 diabetes.

Rocha-Campos AC, Melki R, Zhu R, Deruytter N, Damotte D, Dy M, Herbelin A, Garchon HJ.

Diabetes. 2006 Apr;55(4):1163-70.PMID: 16567543 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of the PTPN22*R620W polymorphism with autoimmune myasthenia gravis.

Vandiedonck C, Capdevielle C, Giraud M, Krumeich S, Jais JP, Eymard B, Tranchant C, Gajdos P, Garchon HJ.

Ann Neurol. 2006 Feb;59(2):404-7.PMID: 16437561 [PubMed - indexed for MEDLINE]Related articles

Association of a common coding polymorphism (N453S) of the cytochrome P450 1B1 (CYP1B1) gene with optic disc cupping and visual field alteration in French patients with primary open-angle glaucoma.

Melki R, Lefort N, Brézin AP, Garchon HJ.

Mol Vis. 2005 Nov 23;11:1012-7.PMID: 16319821 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetics of autoimmune myasthenia gravis: the multifaceted contribution of the HLA complex.

Vandiedonck C, Giraud M, Garchon HJ.

J Autoimmun. 2005;25 Suppl:6-11. Epub 2005 Nov 2. Review.PMID: 16260117 [PubMed - indexed for MEDLINE]Related articles

XMR, a dual location protein in the XY pair and in its associated nucleolus in mouse spermatocytes.

Escalier D, Garchon HJ.

Mol Reprod Dev. 2005 Sep;72(1):105-12.PMID: 15818601 [PubMed - indexed for MEDLINE]Related articles

Mapping non-class II H2-linked loci for type 1 diabetes in nonobese diabetic mice.

Deruytter N, Boulard O, Garchon HJ.

Diabetes. 2004 Dec;53(12):3323-7.PMID: 15561967 [PubMed - indexed for MEDLINE]Related articlesFree article

Pleiotropic effects of the 8.1 HLA haplotype in patients with autoimmune myasthenia gravis and thymus hyperplasia.

Vandiedonck C, Beaurain G, Giraud M, Hue-Beauvais C, Eymard B, Tranchant C, Gajdos P, Dausset J, Garchon HJ.

Proc Natl Acad Sci U S A. 2004 Oct 26;101(43):15464-9. Epub 2004 Oct 15.PMID: 15489265 [PubMed - indexed for MEDLINE]Related articlesFree article

CYP1B1 mutations in French patients with early-onset primary open-angle glaucoma.

Melki R, Colomb E, Lefort N, Brézin AP, Garchon HJ.

J Med Genet. 2004 Sep;41(9):647-51.PMID: 15342693 [PubMed - indexed for MEDLINE]Related articlesFree article

A functional variant of SUMO4, a new I kappa B alpha modifier, is associated with type 1 diabetes.

Guo D, Li M, Zhang Y, Yang P, Eckenrode S, Hopkins D, Zheng W, Purohit S, Podolsky RH, Muir A, Wang J, Dong Z, Brusko T, Atkinson M, Pozzilli P, Zeidler A, Raffel LJ, Jacob CO, Park Y, Serrano-Rios M, Larrad MT, Zhang Z, Garchon HJ, Bach JF, Rotter JI, She JX, Wang CY.

Nat Genet. 2004 Aug;36(8):837-41. Epub 2004 Jul 11. Erratum in: Nat Genet. 2004 Sep;36(9):1024. PMID: 15247916 [PubMed - indexed for MEDLINE]Related articles

Genetic control of autoantibody expression in autoimmune myasthenia gravis: role of the self-antigen and of HLA-linked loci.

Giraud M, Beaurain G, Eymard B, Tranchant C, Gajdos P, Garchon HJ.

Genes Immun. 2004 Aug;5(5):398-404.PMID: 15201863 [PubMed - indexed for MEDLINE]Related articles

Association of the gene encoding the delta-subunit of the muscle acetylcholine receptor (CHRND) with acquired autoimmune myasthenia gravis.

Giraud M, Eymard B, Tranchant C, Gajdos P, Garchon HJ.

Genes Immun. 2004 Jan;5(1):80-3.PMID: 14735155 [PubMed - indexed for MEDLINE]Related articles

Novel cytochrome P450 1B1 (CYP1B1) mutations in patients with primary congenital glaucoma in France.

Colomb E, Kaplan J, Garchon HJ.

Hum Mutat. 2003 Dec;22(6):496.PMID: 14635112 [PubMed - indexed for MEDLINE]Related articles

The M98K variant of the OPTINEURIN (OPTN) gene modifies initial intraocular pressure in patients with primary open angle glaucoma.

Melki R, Belmouden A, Akhayat O, Brézin A, Garchon HJ.

J Med Genet. 2003 Nov;40(11):842-4. No abstract available. PMID: 14627677 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetics of autoimmune myasthenia gravis, a model for antibody-mediated autoimmunity in man.

Garchon HJ.

J Autoimmun. 2003 Sep;21(2):105-10. Review.PMID: 12935778 [PubMed - indexed for MEDLINE]Related articles

Myocilin analysis by DHPLC in French POAG patients: increased prevalence of Q368X mutation.

Melki R, Belmouden A, Brézin A, Garchon HJ.

Hum Mutat. 2003 Aug;22(2):179.PMID: 12872267 [PubMed - indexed for MEDLINE]Related articles

Mutational analysis of the Myocilin gene in patients with primary open-angle glaucoma in Morocco.

Melki R, Idhajji A, Driouiche S, Hassani M, Boukabboucha A, Akhayat O, Garchon H, Belmouden A.

Ophthalmic Genet. 2003 Sep;24(3):153-60.PMID: 12868033 [PubMed - indexed for MEDLINE]Related articles

TNFA-TNFB haplotypes modify susceptibility to type I diabetes mellitus independently of HLA class II in a Moroccan population.

Bouqbis L, Akhayat O, Garchon HJ, Calafell F, Izaabel H.

Tissue Antigens. 2003 Jan;61(1):72-9.PMID: 12622777 [PubMed - indexed for MEDLINE]Related articles

A genome-wide scan for primary open-angle glaucoma (POAG): the Barbados Family Study of Open-Angle Glaucoma.

Nemesure B, Jiao X, He Q, Leske MC, Wu SY, Hennis A, Mendell N, Redman J, Garchon HJ, Agarwala R, Schäffer AA, Hejtmancik F; Barbados Family Study Group.

Hum Genet. 2003 May;112(5-6):600-9. Epub 2003 Mar 4.PMID: 12616399 [PubMed - indexed for MEDLINE]Related articles

Sex-specific gene expression during meiotic prophase I: Xlr (X linked, lymphocyte regulated), not its male homologue Xmr (Xlr related, meiosis regulated), is expressed in mouse oocytes.

Escalier D, Eloy L, Garchon HJ.

Biol Reprod. 2002 Nov;67(5):1646-52.PMID: 12390899 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel frameshift founder mutation in the cytochrome P450 1B1 (CYP1B1) gene is associated with primary congenital glaucoma in Morocco.

Belmouden A, Melki R, Hamdani M, Zaghloul K, Amraoui A, Nadifi S, Akhayat O, Garchon HJ.

Clin Genet. 2002 Oct;62(4):334-9.PMID: 12372064 [PubMed - indexed for MEDLINE]Related articles

Meiotic sex chromosome inactivation in male mice with targeted disruptions of Xist.

Turner JM, Mahadevaiah SK, Elliott DJ, Garchon HJ, Pehrson JR, Jaenisch R, Burgoyne PS.

J Cell Sci. 2002 Nov 1;115(Pt 21):4097-105.PMID: 12356914 [PubMed - indexed for MEDLINE]Related articlesFree article

An interval tightly linked to but distinct from the H2 complex controls both overt diabetes (Idd16) and chronic experimental autoimmune thyroiditis (Ceat1) in nonobese diabetic mice.

Boulard O, Damotte D, Deruytter N, Fluteau G, Carnaud C, Garchon HJ.

Diabetes. 2002 Jul;51(7):2141-7.PMID: 12086944 [PubMed - indexed for MEDLINE]Related articlesFree article

Apolipoprotein E-promoter single-nucleotide polymorphisms affect the phenotype of primary open-angle glaucoma and demonstrate interaction with the myocilin gene.

Copin B, Brézin AP, Valtot F, Dascotte JC, Béchetoille A, Garchon HJ.

Am J Hum Genet. 2002 Jun;70(6):1575-81. Epub 2002 May 3.PMID: 11992263 [PubMed - indexed for MEDLINE]Related articlesFree article

Unexpected sensitivity of nonobese diabetic mice with a disrupted poly(ADP-Ribose) polymerase-1 gene to streptozotocin-induced and spontaneous diabetes.

Gonzalez C, Ménissier De Murcia J, Janiak P, Bidouard JP, Beauvais C, Karray S, Garchon HJ, Lévi-Strauss M.

Diabetes. 2002 May;51(5):1470-6.PMID: 11978644 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic analysis of autoimmune sialadenitis in nonobese diabetic mice: a major susceptibility region on chromosome 1.

Boulard O, Fluteau G, Eloy L, Damotte D, Bedossa P, Garchon HJ.

J Immunol. 2002 Apr 15;168(8):4192-201.PMID: 11937580 [PubMed - indexed for MEDLINE]Related articlesFree article

Further mapping of the Idd5.1 locus for autoimmune diabetes in NOD mice.

Lamhamedi-Cherradi SE, Boulard O, Gonzalez C, Kassis N, Damotte D, Eloy L, Fluteau G, Lévi-Strauss M, Garchon HJ.

Diabetes. 2001 Dec;50(12):2874-8.PMID: 11723074 [PubMed - indexed for MEDLINE]Related articlesFree article

Linkage of HLA to myasthenia gravis and genetic heterogeneity depending on anti-titin antibodies.

Giraud M, Beaurain G, Yamamoto AM, Eymard B, Tranchant C, Gajdos P, Garchon HJ.

Neurology. 2001 Nov 13;57(9):1555-60.PMID: 11706089 [PubMed - indexed for MEDLINE]Related articles

Association of a single nucleotide polymorphism in the TIGR/MYOCILIN gene promoter with the severity of primary open-angle glaucoma.

Colomb E, Nguyen TD, Béchetoille A, Dascotte JC, Valtot F, Brézin AP, Berkani M, Copin B, Gomez L, Polansky JR, Garchon HJ.

Clin Genet. 2001 Sep;60(3):220-5.PMID: 11595024 [PubMed - indexed for MEDLINE]Related articles

Genetics of human type 1 diabetes mellitus.

Bach JF, Garchon HJ, van Endert P.

Curr Dir Autoimmun. 2001;4:1-30. Review. No abstract available. PMID: 11569399 [PubMed - indexed for MEDLINE]Related articles

Genetic influences on the end-stage effector phase of arthritis.

Ji H, Gauguier D, Ohmura K, Gonzalez A, Duchatelle V, Danoy P, Garchon HJ, Degott C, Lathrop M, Benoist C, Mathis D.

J Exp Med. 2001 Aug 6;194(3):321-30.PMID: 11489951 [PubMed - indexed for MEDLINE]Related articlesFree article

Anti-titin antibodies in myasthenia gravis: tight association with thymoma and heterogeneity of nonthymoma patients.

Yamamoto AM, Gajdos P, Eymard B, Tranchant C, Warter JM, Gomez L, Bourquin C, Bach JF, Garchon HJ.

Arch Neurol. 2001 Jun;58(6):885-90.PMID: 11405802 [PubMed - indexed for MEDLINE]Related articlesFree article

CTLA-4-/- mice display T cell-apoptosis resistance resembling that ascribed to autoimmune-prone non-obese diabetic (NOD) mice.

Bergman ML, Cilio CM, Penha-Gonçalves C, Lamhamedi-Cherradi SE, Löfgren A, Colucci F, Lejon K, Garchon HJ, Holmberg D.

J Autoimmun. 2001 Mar;16(2):105-13.PMID: 11247636 [PubMed - indexed for MEDLINE]Related articles

Protection against diabetes and improved NK/NKT cell performance in NOD.NK1.1 mice congenic at the NK complex.

Carnaud C, Gombert J, Donnars O, Garchon H, Herbelin A.

J Immunol. 2001 Feb 15;166(4):2404-11.PMID: 11160299 [PubMed - indexed for MEDLINE]Related articlesFree article

XMR is associated with the asynapsed segments of sex chromosomes in the XY body of mouse primary spermatocytes.

Escalier D, Garchon HJ.

Chromosoma. 2000 Jul;109(4):259-65.PMID: 10968254 [PubMed - indexed for MEDLINE]Related articles

Genetic and physical mapping of a type 1 diabetes susceptibility gene (IDDM12) to a 100-kb phagemid artificial chromosome clone containing D2S72-CTLA4-D2S105 on chromosome 2q33.

Marron MP, Zeidler A, Raffel LJ, Eckenrode SE, Yang JJ, Hopkins DI, Garchon HJ, Jacob CO, Serrano-Rios M, Martinez Larrad MT, Park Y, Bach JF, Rotter JI, Yang MC, She JX.

Diabetes. 2000 Mar;49(3):492-9.PMID: 10868973 [PubMed - indexed for MEDLINE]Related articlesFree article

High level expression of the Xlr nuclear protein in immature thymocytes and colocalization with the matrix-associated region-binding SATB1 protein.

Escalier D, Allenet B, Badrichani A, Garchon HJ.

J Immunol. 1999 Jan 1;162(1):292-8.PMID: 9886398 [PubMed - indexed for MEDLINE]Related articlesFree article

Young age and HLA markers enhance the risk of progression to type 1 diabetes in antibody-positive siblings of diabetic children.

Yamamoto AM, Deschamps I, Garchon HJ, Roussely H, Moreau N, Beaurain G, Robert JJ, Bach JF.

J Autoimmun. 1998 Dec;11(6):643-50.PMID: 9878086 [PubMed - indexed for MEDLINE]Related articles

Novel TIGR/MYOC mutations in families with juvenile onset primary open angle glaucoma.

Stoilova D, Child A, Brice G, Desai T, Barsoum-Homsy M, Ozdemir N, Chevrette L, Adam MF, Garchon HJ, Pitts Crick R, Sarfarazi M.

J Med Genet. 1998 Dec;35(12):989-92.PMID: 9863594 [PubMed - indexed for MEDLINE]Related articlesFree article

N-terminus cleavage of bcl-2 by a novel cellular non-ICE cysteine proteinase.

Yamamoto AM, Eloy L, Bach JF, Garchon HJ.

Leukemia. 1998 Sep;12(9):1467-72.PMID: 9737698 [PubMed - indexed for MEDLINE]Related articles

Founder effect in GLC1A-linked familial open-angle glaucoma in Northern France.

Brézin AP, Adam MF, Belmouden A, Lureau MA, Chaventré A, Copin B, Gomez L, De Dinechin SD, Berkani M, Valtot F, Rouland JF, Dascotte JC, Bach JF, Garchon HJ.

Am J Med Genet. 1998 Apr 13;76(5):438-45.PMID: 9556305 [PubMed - indexed for MEDLINE]Related articles

Resistance of T-cells to apoptosis in autoimmune diabetic (NOD) mice is increased early in life and is associated with dysregulated expression of Bcl-x.

Lamhamedi-Cherradi SE, Luan JJ, Eloy L, Fluteau G, Bach JF, Garchon HJ.

Diabetologia. 1998 Feb;41(2):178-84.PMID: 9498651 [PubMed - indexed for MEDLINE]Related articles

HLA class II DNA polymorphism in a Moroccan population from the Souss, Agadir area.

Izaabel H, Garchon HJ, Caillat-Zucman S, Beaurain G, Akhayat O, Bach JF, Sanchez-Mazas A.

Tissue Antigens. 1998 Jan;51(1):106-10.PMID: 9459511 [PubMed - indexed for MEDLINE]Related articles

Recurrent mutations in a single exon encoding the evolutionarily conserved olfactomedin-homology domain of TIGR in familial open-angle glaucoma.

Adam MF, Belmouden A, Binisti P, Brézin AP, Valtot F, Béchetoille A, Dascotte JC, Copin B, Gomez L, Chaventré A, Bach JF, Garchon HJ.

Hum Mol Genet. 1997 Nov;6(12):2091-7.PMID: 9328473 [PubMed - indexed for MEDLINE]Related articlesFree article

No evidence for an association of AChR beta-subunit gene (CHRNB1) with myasthenia gravis.

Djabiri F, Gajdos P, Eymard B, Gomez L, Bach JF, Garchon HJ.

J Neuroimmunol. 1997 Sep;78(1-2):86-9.PMID: 9307231 [PubMed - indexed for MEDLINE]Related articles