PubMed

Phase I trial of a combination of the multikinase inhibitor sorafenib and the farnesyltransferase inhibitor tipifarnib in advanced malignancies.

Hong DS, Sebti SM, Newman RA, Blaskovich MA, Ye L, Gagel RF, Moulder S, Wheler JJ, Naing A, Tannir NM, Ng CS, Sherman SI, El Naggar AK, Khan R, Trent J, Wright JJ, Kurzrock R.

Clin Cancer Res. 2009 Nov 15;15(22):7061-8. Epub 2009 Nov 10.PMID: 19903778 [PubMed - in process]Related articles

NCCN Task Force Report: Bone Health in Cancer Care.

Gralow JR, Biermann JS, Farooki A, Fornier MN, Gagel RF, Kumar RN, Shapiro CL, Shields A, Smith MR, Srinivas S, Van Poznak CH.

J Natl Compr Canc Netw. 2009 Jun;7 Suppl 3:S1-S32; quiz S33-S35.PMID: 19555589 [PubMed - indexed for MEDLINE]Related articles

The calcitonin/calcitonin gene related peptide-alpha gene is not required for 1alpha,25-dihydroxyvitamin D3-mediated suppression of experimental autoimmune encephalomyelitis.

Becklund BR, James BJ, Gagel RF, DeLuca HF.

Arch Biochem Biophys. 2009 Aug 15;488(2):105-8. Epub 2009 Jun 27.PMID: 19563774 [PubMed - indexed for MEDLINE]Related articles

Targeted therapy for endocrine cancer: the medullary thyroid carcinoma paradigm.

Ye L, Santarpia L, Gagel RF.

Endocr Pract. 2009 Sep-Oct;15(6):597-604.PMID: 19546050 [PubMed - in process]Related articles

Beyond RET: potential therapeutic approaches for advanced and metastatic medullary thyroid carcinoma.

Santarpia L, Ye L, Gagel RF.

J Intern Med. 2009 Jul;266(1):99-113. Review.PMID: 19522829 [PubMed - indexed for MEDLINE]Related articles

Medullary thyroid cancer: management guidelines of the American Thyroid Association.

American Thyroid Association Guidelines Task Force, Kloos RT, Eng C, Evans DB, Francis GL, Gagel RF, Gharib H, Moley JF, Pacini F, Ringel MD, Schlumberger M, Wells SA Jr.

Thyroid. 2009 Jun;19(6):565-612. Review.PMID: 19469690 [PubMed - indexed for MEDLINE]Related articles

Expression analysis of fibroblast growth factor-23, matrix extracellular phosphoglycoprotein, secreted frizzled-related protein-4, and fibroblast growth factor-7: identification of fibroblast growth factor-23 and matrix extracellular phosphoglycoprotein as major factors involved in tumor-induced osteomalacia.

Habra MA, Jimenez C, Huang SC, Cote GJ, Murphy WA Jr, Gagel RF, Hoff AO.

Endocr Pract. 2008 Dec;14(9):1108-14.PMID: 19158050 [PubMed - indexed for MEDLINE]Related articles

Diabetes insipidus and panhypopituitarism due to intrasellar metastasis from medullary thyroid cancer.

Santarpia L, Gagel RF, Sherman SI, Sarlis NJ, Evans DB, Hoff AO.

Head Neck. 2009 Mar;31(3):419-23.PMID: 18798312 [PubMed - indexed for MEDLINE]Related articles

High resolution array-comparative genomic hybridization profiling reveals deoxyribonucleic acid copy number alterations associated with medullary thyroid carcinoma.

Ye L, Santarpia L, Cote GJ, El-Naggar AK, Gagel RF.

J Clin Endocrinol Metab. 2008 Nov;93(11):4367-72. Epub 2008 Sep 2.PMID: 18765511 [PubMed - indexed for MEDLINE]Related articlesFree article

Follow-up of pituitary tumor volume in patients with acromegaly treated with pegvisomant in clinical trials.

Jimenez C, Burman P, Abs R, Clemmons DR, Drake WM, Hutson KR, Messig M, Thorner MO, Trainer PJ, Gagel RF.

Eur J Endocrinol. 2008 Nov;159(5):517-23. Epub 2008 Aug 15.PMID: 18708436 [PubMed - indexed for MEDLINE]Related articlesFree article

Four patients with cutaneous metastases from medullary thyroid cancer.

Santarpia L, El-Naggar AK, Sherman SI, Hymes SR, Gagel RF, Shaw S, Sarlis NJ.

Thyroid. 2008 Aug;18(8):901-5.PMID: 18651821 [PubMed - indexed for MEDLINE]Related articles

Frequency and risk factors associated with osteonecrosis of the jaw in cancer patients treated with intravenous bisphosphonates.

Hoff AO, Toth BB, Altundag K, Johnson MM, Warneke CL, Hu M, Nooka A, Sayegh G, Guarneri V, Desrouleaux K, Cui J, Adamus A, Gagel RF, Hortobagyi GN.

J Bone Miner Res. 2008 Jun;23(6):826-36.PMID: 18558816 [PubMed - indexed for MEDLINE]Related articlesFree article

Management of medullary thyroid carcinoma.

Jiménez C, Hu MI, Gagel RF.

Endocrinol Metab Clin North Am. 2008 Jun;37(2):481-96, x-xi. Review.PMID: 18502338 [PubMed - indexed for MEDLINE]Related articles

Oral bisphosphonate-induced osteonecrosis: risk factors, prediction of risk using serum CTX testing, prevention, and treatment.

American Society for Bone and Mineral Research Task Force on Osteonecrosis of the Jaw, Khosla S, Burr D, Cauley J, Dempster DW, Ebeling PR, Felsenberg D, Gagel RF, Gilsanz V, Guise T, Koka S, McCauley LK, McGowan J, McKee MD, Mohla S, Pendrys DG, Raisz LG, Ruggiero SL, Shafer DM, Shum L, Silverman SL, Van Poznak CH, Watts N, Woo SB, Shane E.

J Oral Maxillofac Surg. 2008 Jun;66(6):1320-1; author reply 1321-2. No abstract available. Erratum in: J Oral Maxillofac Surg. 2008 Aug;66(8):1778. PMID: 18486811 [PubMed - indexed for MEDLINE]Related articles

Bone loss in patients with breast or prostate cancer.

Hu MI, Gagel RF, Jimenez C.

Curr Osteoporos Rep. 2007 Dec;5(4):170-8. Review.PMID: 18430392 [PubMed - indexed for MEDLINE]Related articles

Recent advances in thyroid cancer.

Grubbs EG, Rich TA, Li G, Sturgis EM, Younes MN, Myers JN, Edeiken-Monroe B, Fornage BD, Monroe DP, Staerkel GA, Williams MD, Waguespack SG, Hu MI, Cote G, Gagel RF, Cohen J, Weber RS, Anaya DA, Holsinger FC, Perrier ND, Clayman GL, Evans DB.

Curr Probl Surg. 2008 Mar;45(3):156-250. No abstract available. PMID: 18346477 [PubMed - indexed for MEDLINE]Related articles

Recent advances in thyroid cancer. In brief.

Grubbs EG, Rich TA, Li G, Sturgis EM, Younes MN, Myers JN, Edeiken-Monroe B, Fornage BD, Monroe DP, Staerkel GA, Williams MD, Waguespack SG, Hu MI, Cote G, Gagel RF, Cohen J, Weber RS, Anaya DA, Holsinger FC, Perrier ND, Clayman GL, Evans DB.

Curr Probl Surg. 2008 Mar;45(3):149-51. No abstract available. PMID: 18346476 [PubMed - indexed for MEDLINE]Related articles

Bisphosphonate-associated osteonecrosis of the jaw: report of a task force of the American Society for Bone and Mineral Research.

Khosla S, Burr D, Cauley J, Dempster DW, Ebeling PR, Felsenberg D, Gagel RF, Gilsanz V, Guise T, Koka S, McCauley LK, McGowan J, McKee MD, Mohla S, Pendrys DG, Raisz LG, Ruggiero SL, Shafer DM, Shum L, Silverman SL, Van Poznak CH, Watts N, Woo SB, Shane E; American Society for Bone and Mineral Research.

J Bone Miner Res. 2007 Oct;22(10):1479-91.PMID: 17663640 [PubMed - indexed for MEDLINE]Related articles

Thyroid carcinoma.

Sherman SI, Angelos P, Ball DW, Byrd D, Clark OH, Daniels GH, Dilawari RA, Ehya H, Farrar WB, Gagel RF, Kandeel F, Kloos RT, Kopp P, Lamonica DM, Loree TR, Lydiatt WM, McCaffrey J, Olson JA Jr, Ridge JA, Shah JP, Sisson JC, Tuttle RM, Urist MM; National Comprehensive Cancer Network Thyroid Carcinoma Panel.

J Natl Compr Canc Netw. 2007 Jul;5(6):568-621. No abstract available. PMID: 17623612 [PubMed - indexed for MEDLINE]Related articles

ASCO/SSO review of current role of risk-reducing surgery in common hereditary cancer syndromes.

Guillem JG, Wood WC, Moley JF, Berchuck A, Karlan BY, Mutch DG, Gagel RF, Weitzel J, Morrow M, Weber BL, Giardiello F, Rodriguez-Bigas MA, Church J, Gruber S, Offit K; ASCO; SSO.

J Clin Oncol. 2006 Oct 1;24(28):4642-60. Review.PMID: 17008706 [PubMed - indexed for MEDLINE]Related articles

ASCO/SSO review of current role of risk-reducing surgery in common hereditary cancer syndromes.

Guillem JG, Wood WC, Moley JF, Berchuck A, Karlan BY, Mutch DG, Gagel RF, Weitzel J, Morrow M, Weber BL, Giardiello F, Rodriguez-Bigas MA, Church J, Gruber S, Offit K.

Ann Surg Oncol. 2006 Oct;13(10):1296-321. Review.PMID: 16990987 [PubMed - indexed for MEDLINE]Related articles

Review: Should patients with apparently sporadic pheochromocytomas or paragangliomas be screened for hereditary syndromes?

Jiménez C, Cote G, Arnold A, Gagel RF.

J Clin Endocrinol Metab. 2006 Aug;91(8):2851-8. Epub 2006 May 30. Review.PMID: 16735498 [PubMed - indexed for MEDLINE]Related articlesFree article

Management of pancreatic endocrine tumors in multiple endocrine neoplasia type 1.

Kouvaraki MA, Shapiro SE, Cote GJ, Lee JE, Yao JC, Waguespack SG, Gagel RF, Evans DB, Perrier ND.

World J Surg. 2006 May;30(5):643-53.PMID: 16680581 [PubMed - indexed for MEDLINE]Related articles

Calcitonin plays a critical role in regulating skeletal mineral metabolism during lactation.

Woodrow JP, Sharpe CJ, Fudge NJ, Hoff AO, Gagel RF, Kovacs CS.

Endocrinology. 2006 Sep;147(9):4010-21. Epub 2006 May 4.PMID: 16675524 [PubMed - indexed for MEDLINE]Related articlesFree article

Thyrotoxicosis after denileukin diftitox therapy in patients with mycosis fungoides.

Ghori F, Polder KD, Pinter-Brown LC, Hoff AO, Gagel RF, Sherman SI, Duvic M.

J Clin Endocrinol Metab. 2006 Jun;91(6):2205-8. Epub 2006 Apr 4.PMID: 16595600 [PubMed - indexed for MEDLINE]Related articlesFree article

Teriparatide [human PTH(1-34)]: 2.5 years of experience on the use and safety of the drug for the treatment of osteoporosis.

Tashjian AH Jr, Gagel RF.

J Bone Miner Res. 2006 Mar;21(3):354-65. Epub 2005 Nov 11. Review. No abstract available. PMID: 16491282 [PubMed - indexed for MEDLINE]Related articles

Glucose homeostasis and safety in patients with acromegaly converted from long-acting octreotide to pegvisomant.

Barkan AL, Burman P, Clemmons DR, Drake WM, Gagel RF, Harris PE, Trainer PJ, van der Lely AJ, Vance ML.

J Clin Endocrinol Metab. 2005 Oct;90(10):5684-91. Epub 2005 Aug 2.PMID: 16076947 [PubMed - indexed for MEDLINE]Related articlesFree article

Primary hyperparathyroidism and osteosarcoma: examination of a large cohort identifies three cases of fibroblastic osteosarcoma.

Jimenez C, Yang Y, Kim HW, Al-Sagier F, Berry DA, El-Naggar AK, Patel S, Vassilopoulou-Sellin R, Gagel RF.

J Bone Miner Res. 2005 Sep;20(9):1562-8. Epub 2005 May 9.PMID: 16059628 [PubMed - indexed for MEDLINE]Related articles

RET proto-oncogene: a review and update of genotype-phenotype correlations in hereditary medullary thyroid cancer and associated endocrine tumors.

Kouvaraki MA, Shapiro SE, Perrier ND, Cote GJ, Gagel RF, Hoff AO, Sherman SI, Lee JE, Evans DB.

Thyroid. 2005 Jun;15(6):531-44. Review.PMID: 16029119 [PubMed - indexed for MEDLINE]Related articles

Thyroid carcinoma.

Sherman SI, Angelos P, Ball DW, Beenken SW, Byrd D, Clark OH, Daniels GH, Dilawari RA, Ehya H, Farrar WB, Gagel RF, Kandeel F, Kloos RT, Kopp P, Lamonica DM, Loree TR, Lydiatt WM, McCaffrey J, Olson JA Jr, Ridge JA, Robbins R, Shah JP, Sisson JC, Thompson NW; National Comprehensive Cancer Network.

J Natl Compr Canc Netw. 2005 May;3(3):404-57. No abstract available. PMID: 16002006 [PubMed - indexed for MEDLINE]Related articles

Osteoporosis in breast and prostate cancer survivors.

Hoff AO, Gagel RF.

Oncology (Williston Park). 2005 Apr;19(5):651-8. Review.PMID: 15945345 [PubMed - indexed for MEDLINE]Related articles

Surgical treatment of hyperparathyroidism in patients with multiple endocrine neoplasia type 1.

Lambert LA, Shapiro SE, Lee JE, Perrier ND, Truong M, Wallace MJ, Hoff AO, Gagel RF, Evans DB.

Arch Surg. 2005 Apr;140(4):374-82.PMID: 15841561 [PubMed - indexed for MEDLINE]Related articlesFree article

Decreased bone formation and osteopenia in mice lacking alpha-calcitonin gene-related peptide.

Schinke T, Liese S, Priemel M, Haberland M, Schilling AF, Catala-Lehnen P, Blicharski D, Rueger JM, Gagel RF, Emeson RB, Amling M.

J Bone Miner Res. 2004 Dec;19(12):2049-56. Epub 2004 Sep 20.PMID: 15537449 [PubMed - indexed for MEDLINE]Related articles

Pheochromocytoma and medullary thyroid carcinoma: a new genotype-phenotype correlation of the RET protooncogene 891 germline mutation.

Jimenez C, Habra MA, Huang SC, El-Naggar A, Shapiro SE, Evans DB, Cote G, Gagel RF.

J Clin Endocrinol Metab. 2004 Aug;89(8):4142-5.PMID: 15292360 [PubMed - indexed for MEDLINE]Related articlesFree article

Parathyroid carcinoma: a 22-year experience.

Busaidy NL, Jimenez C, Habra MA, Schultz PN, El-Naggar AK, Clayman GL, Asper JA, Diaz EM Jr, Evans DB, Gagel RF, Garden A, Hoff AO, Lee JE, Morrison WH, Rosenthal DI, Sherman SI, Sturgis EM, Waguespack SG, Weber RS, Wirfel K, Vassilopoulou-Sellin R.

Head Neck. 2004 Aug;26(8):716-26.PMID: 15287039 [PubMed - indexed for MEDLINE]Related articles

A novel point mutation of the RET protooncogene involving the second intracellular tyrosine kinase domain in a family with medullary thyroid carcinoma.

Jimenez C, Dang GT, Schultz PN, El-Naggar A, Shapiro S, Barnes EA, Evans DB, Vassilopoulou-Sellin R, Gagel RF, Cote GJ, Hoff AO.

J Clin Endocrinol Metab. 2004 Jul;89(7):3521-6.PMID: 15240641 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic testing in endocrinology: lessons learned from experience with multiple endocrine neoplasia type 2 (MEN2).

Jimenez C, Gagel RF.

Growth Horm IGF Res. 2004 Jun;14 Suppl A:S150-7. Review.PMID: 15135800 [PubMed - indexed for MEDLINE]Related articles

Surgical management of hereditary pheochromocytoma.

Yip L, Lee JE, Shapiro SE, Waguespack SG, Sherman SI, Hoff AO, Gagel RF, Arens JF, Evans DB.

J Am Coll Surg. 2004 Apr;198(4):525-34; discussion 534-5.PMID: 15051000 [PubMed - indexed for MEDLINE]Related articles

Ablation of calcitonin/calcitonin gene-related peptide-alpha impairs fetal magnesium but not calcium homeostasis.

McDonald KR, Fudge NJ, Woodrow JP, Friel JK, Hoff AO, Gagel RF, Kovacs CS.

Am J Physiol Endocrinol Metab. 2004 Aug;287(2):E218-26. Epub 2004 Mar 23.PMID: 15039145 [PubMed - indexed for MEDLINE]Related articlesFree article

Potential role for intraoperative gamma probe identification of normal parathyroid glands.

Pederson LC, Shapiro SE, Fritsche HA Jr, Delpassand ES, Gagel RF, Sherman SI, Vassilopoulou-Sellin R, Evans DB, Lee JE.

Am J Surg. 2003 Dec;186(6):711-7.PMID: 14672784 [PubMed - indexed for MEDLINE]Related articles

Sarcomatous change after sellar irradiation in a growth hormone-secreting pituitary adenoma.

Prabhu SS, Aldape KD, Gagel RF, Benjamin RS, Trent JC, McCutcheon IE.

Can J Neurol Sci. 2003 Nov;30(4):378-83.PMID: 14672272 [PubMed - indexed for MEDLINE]Related articles

Medullary thyroid carcinoma: results of a standardized surgical approach in a contemporary series of 80 consecutive patients.

Yen TW, Shapiro SE, Gagel RF, Sherman SI, Lee JE, Evans DB.

Surgery. 2003 Dec;134(6):890-9; discussion 899-901.PMID: 14668720 [PubMed - indexed for MEDLINE]Related articles

The role of genetics in the surgical management of familial endocrinopathy syndromes.

Shapiro SE, Cote GC, Lee JE, Gagel RF, Evans DB.

J Am Coll Surg. 2003 Nov;197(5):818-31. Review. No abstract available. PMID: 14585420 [PubMed - indexed for MEDLINE]Related articles

Lessons learned from the management of a rare genetic cancer.

Cote GJ, Gagel RF.

N Engl J Med. 2003 Oct 16;349(16):1566-8. No abstract available. PMID: 14561800 [PubMed - indexed for MEDLINE]Related articles

Multiple endocrine neoplasia type 2: evaluation of the genotype-phenotype relationship.

Yip L, Cote GJ, Shapiro SE, Ayers GD, Herzog CE, Sellin RV, Sherman SI, Gagel RF, Lee JE, Evans DB.

Arch Surg. 2003 Apr;138(4):409-16; discussion 416.PMID: 12686527 [PubMed - indexed for MEDLINE]Related articlesFree article

Amplification and overexpression of mutant RET in multiple endocrine neoplasia type 2-associated medullary thyroid carcinoma.

Huang SC, Torres-Cruz J, Pack SD, Koch CA, Vortmeyer AO, Mannan P, Lubensky IA, Gagel RF, Zhuang Z.

J Clin Endocrinol Metab. 2003 Jan;88(1):459-63.PMID: 12519890 [PubMed - indexed for MEDLINE]Related articlesFree article

Improving the yield of preoperative parathyroid localization: technetium Tc 99m-sestamibi imaging after thyroid suppression.

Royal RE, Delpassand ES, Shapiro SE, Fritsche HA Jr, Vassilopoulou-Sellin R, Sherman SI, Gagel RF, Evans DB, Lee JE.

Surgery. 2002 Dec;132(6):968-74; discussion 974-5.PMID: 12490843 [PubMed - indexed for MEDLINE]Related articles

Increased bone mass is an unexpected phenotype associated with deletion of the calcitonin gene.

Hoff AO, Catala-Lehnen P, Thomas PM, Priemel M, Rueger JM, Nasonkin I, Bradley A, Hughes MR, Ordonez N, Cote GJ, Amling M, Gagel RF.

J Clin Invest. 2002 Dec;110(12):1849-57.PMID: 12488435 [PubMed - indexed for MEDLINE]Related articlesFree article

Naturally occurring heterologous trans-splicing of adenovirus RNA with host cellular transcripts during infection.

Kikumori T, Cote GJ, Gagel RF.

FEBS Lett. 2002 Jul 3;522(1-3):41-6.PMID: 12095616 [PubMed - indexed for MEDLINE]Related articles

Genotype-phenotype analysis in multiple endocrine neoplasia type 1.

Kouvaraki MA, Lee JE, Shapiro SE, Gagel RF, Sherman SI, Sellin RV, Cote GJ, Evans DB.

Arch Surg. 2002 Jun;137(6):641-7.PMID: 12049533 [PubMed - indexed for MEDLINE]Related articlesFree article