PubMed

No Evidence of PGRN or MAPT Gene Dosage Alterations in a Collection of Patients with Frontotemporal Lobar Degeneration.

Skoglund L, Ingvast S, Matsui T, Freeman SH, Frosch MP, Brundin R, Giedraitis V, Growdon JH, Hyman BT, Lannfelt L, Ingelsson M, Glaser A.

Dement Geriatr Cogn Disord. 2009 Nov 23;28(5):471-475. [Epub ahead of print]PMID: 19940479 [PubMed - as supplied by publisher]Related articles

The Gly2019Ser mutation in LRRK2 is not fully penetrant in familial Parkinson's disease: the GenePD study.

Latourelle JC, Sun M, Lew MF, Suchowersky O, Klein C, Golbe LI, Mark MH, Growdon JH, Wooten GF, Watts RL, Guttman M, Racette BA, Perlmutter JS, Ahmed A, Shill HA, Singer C, Goldwurm S, Pezzoli G, Zini M, Saint-Hilaire MH, Hendricks AE, Williamson S, Nagle MW, Wilk JB, Massood T, Huskey KW, Laramie JM, DeStefano AL, Baker KB, Itin I, Litvan I, Nicholson G, Corbett A, Nance M, Drasby E, Isaacson S, Burn DJ, Chinnery PF, Pramstaller PP, Al-hinti J, Moller AT, Ostergaard K, Sherman SJ, Roxburgh R, Snow B, Slevin JT, Cambi F, Gusella JF, Myers RH.

BMC Med. 2008 Nov 5;6:32.PMID: 18986508 [PubMed - indexed for MEDLINE]Related articlesFree article

Shorter telomeres may mark early risk of dementia: preliminary analysis of 62 participants from the nurses' health study.

Grodstein F, van Oijen M, Irizarry MC, Rosas HD, Hyman BT, Growdon JH, De Vivo I.

PLoS One. 2008 Feb 13;3(2):e1590.PMID: 18795148 [PubMed - indexed for MEDLINE]Related articlesFree article

Imaging amyloid deposition in Lewy body diseases.

Gomperts SN, Rentz DM, Moran E, Becker JA, Locascio JJ, Klunk WE, Mathis CA, Elmaleh DR, Shoup T, Fischman AJ, Hyman BT, Growdon JH, Johnson KA.

Neurology. 2008 Sep 16;71(12):903-10.PMID: 18794492 [PubMed - indexed for MEDLINE]Related articlesFree article

Huntington CAG repeat size does not modify onset age in familial Parkinson's disease: the GenePD study.

McNicoll CF, Latourelle JC, MacDonald ME, Lew MF, Suchowersky O, Klein C, Golbe LI, Mark MH, Growdon JH, Wooten GF, Watts RL, Guttman M, Racette BA, Perlmutter JS, Ahmed A, Shill HA, Singer C, Saint-Hilaire MH, Massood T, Huskey KW, DeStefano AL, Gillis T, Mysore J, Goldwurm S, Pezzoli G, Baker KB, Itin I, Litvan I, Nicholson G, Corbett A, Nance M, Drasby E, Isaacson S, Burn DJ, Chinnery PF, Pramstaller PP, Al-Hinti J, Moller AT, Ostergaard K, Sherman SJ, Roxburgh R, Snow B, Slevin JT, Cambi F, Gusella JF, Myers RH.

Mov Disord. 2008 Aug 15;23(11):1596-601.PMID: 18649400 [PubMed - indexed for MEDLINE]Related articlesFree article

The cortical signature of Alzheimer's disease: regionally specific cortical thinning relates to symptom severity in very mild to mild AD dementia and is detectable in asymptomatic amyloid-positive individuals.

Dickerson BC, Bakkour A, Salat DH, Feczko E, Pacheco J, Greve DN, Grodstein F, Wright CI, Blacker D, Rosas HD, Sperling RA, Atri A, Growdon JH, Hyman BT, Morris JC, Fischl B, Buckner RL.

Cereb Cortex. 2009 Mar;19(3):497-510. Epub 2008 Jul 16.PMID: 18632739 [PubMed - in process]Related articlesFree article

Replication of association between ELAVL4 and Parkinson disease: the GenePD study.

DeStefano AL, Latourelle J, Lew MF, Suchowersky O, Klein C, Golbe LI, Mark MH, Growdon JH, Wooten GF, Watts R, Guttman M, Racette BA, Perlmutter JS, Marlor L, Shill HA, Singer C, Goldwurm S, Pezzoli G, Saint-Hilaire MH, Hendricks AE, Gower A, Williamson S, Nagle MW, Wilk JB, Massood T, Huskey KW, Baker KB, Itin I, Litvan I, Nicholson G, Corbett A, Nance M, Drasby E, Isaacson S, Burn DJ, Chinnery PF, Pramstaller PP, Al-Hinti J, Moller AT, Ostergaard K, Sherman SJ, Roxburgh R, Snow B, Slevin JT, Cambi F, Gusella JF, Myers RH.

Hum Genet. 2008 Aug;124(1):95-9. Epub 2008 Jun 29.PMID: 18587682 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term course and effectiveness of combination therapy in Alzheimer disease.

Atri A, Shaughnessy LW, Locascio JJ, Growdon JH.

Alzheimer Dis Assoc Disord. 2008 Jul-Sep;22(3):209-21.PMID: 18580597 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasma amyloid beta-protein and C-reactive protein in relation to the rate of progression of Alzheimer disease.

Locascio JJ, Fukumoto H, Yap L, Bottiglieri T, Growdon JH, Hyman BT, Irizarry MC.

Arch Neurol. 2008 Jun;65(6):776-85.PMID: 18541797 [PubMed - indexed for MEDLINE]Related articlesFree article

Haplotypes and gene expression implicate the MAPT region for Parkinson disease: the GenePD Study.

Tobin JE, Latourelle JC, Lew MF, Klein C, Suchowersky O, Shill HA, Golbe LI, Mark MH, Growdon JH, Wooten GF, Racette BA, Perlmutter JS, Watts R, Guttman M, Baker KB, Goldwurm S, Pezzoli G, Singer C, Saint-Hilaire MH, Hendricks AE, Williamson S, Nagle MW, Wilk JB, Massood T, Laramie JM, DeStefano AL, Litvan I, Nicholson G, Corbett A, Isaacson S, Burn DJ, Chinnery PF, Pramstaller PP, Sherman S, Al-hinti J, Drasby E, Nance M, Moller AT, Ostergaard K, Roxburgh R, Snow B, Slevin JT, Cambi F, Gusella JF, Myers RH.

Neurology. 2008 Jul 1;71(1):28-34. Epub 2008 May 28.PMID: 18509094 [PubMed - indexed for MEDLINE]Related articlesFree article

White matter pathology isolates the hippocampal formation in Alzheimer's disease.

Salat DH, Tuch DS, van der Kouwe AJ, Greve DN, Pappu V, Lee SY, Hevelone ND, Zaleta AK, Growdon JH, Corkin S, Fischl B, Rosas HD.

Neurobiol Aging. 2008 May 2. [Epub ahead of print]PMID: 18455835 [PubMed - as supplied by publisher]Related articles

How to solve three puzzles.

Munir K, Coulter S, Growdon JH, MacDonald A, Skerrett PJ, Leopold JA.

Newsweek. 2008 Jan 21;151(3):64, 66. No abstract available. PMID: 18314825 [PubMed - indexed for MEDLINE]Related articles

TAR-DNA binding protein 43 in Pick disease.

Freeman SH, Spires-Jones T, Hyman BT, Growdon JH, Frosch MP.

J Neuropathol Exp Neurol. 2008 Jan;67(1):62-7.PMID: 18091558 [PubMed - indexed for MEDLINE]Related articles

Analysis of feature space for monitoring persons with Parkinson's disease with application to a wireless wearable sensor system.

Patel S, Lorincz K, Hughes R, Huggins N, Growdon JH, Welsh M, Bonato P.

Conf Proc IEEE Eng Med Biol Soc. 2007;2007:6291-4.PMID: 18003459 [PubMed - indexed for MEDLINE]Related articles

Plasma F2A isoprostane levels in Alzheimer's and Parkinson's disease.

Irizarry MC, Yao Y, Hyman BT, Growdon JH, Praticò D.

Neurodegener Dis. 2007;4(6):403-5. Epub 2007 Oct 9.PMID: 17934322 [PubMed - indexed for MEDLINE]Related articles

Increase in the relative expression of tau with four microtubule binding repeat regions in frontotemporal lobar degeneration and progressive supranuclear palsy brains.

Ingelsson M, Ramasamy K, Russ C, Freeman SH, Orne J, Raju S, Matsui T, Growdon JH, Frosch MP, Ghetti B, Brown RH, Irizarry MC, Hyman BT.

Acta Neuropathol. 2007 Nov;114(5):471-9. Epub 2007 Aug 25.PMID: 17721707 [PubMed - indexed for MEDLINE]Related articles

DLB and PDD boundary issues: diagnosis, treatment, molecular pathology, and biomarkers.

Lippa CF, Duda JE, Grossman M, Hurtig HI, Aarsland D, Boeve BF, Brooks DJ, Dickson DW, Dubois B, Emre M, Fahn S, Farmer JM, Galasko D, Galvin JE, Goetz CG, Growdon JH, Gwinn-Hardy KA, Hardy J, Heutink P, Iwatsubo T, Kosaka K, Lee VM, Leverenz JB, Masliah E, McKeith IG, Nussbaum RL, Olanow CW, Ravina BM, Singleton AB, Tanner CM, Trojanowski JQ, Wszolek ZK; DLB/PDD Working Group.

Neurology. 2007 Mar 13;68(11):812-9. Review.PMID: 17353469 [PubMed - indexed for MEDLINE]Related articles

Molecular imaging with Pittsburgh Compound B confirmed at autopsy: a case report.

Bacskai BJ, Frosch MP, Freeman SH, Raymond SB, Augustinack JC, Johnson KA, Irizarry MC, Klunk WE, Mathis CA, Dekosky ST, Greenberg SM, Hyman BT, Growdon JH.

Arch Neurol. 2007 Mar;64(3):431-4.PMID: 17353389 [PubMed - indexed for MEDLINE]Related articlesFree article

Tau missing from CSF: a case report.

Alberici A, Armani M, Paterlini A, Benussi L, Nicosia F, Ghidoni R, Signorini S, Cotelli M, Frisoni GB, Geroldi C, Trevisan CP, Growdon JH, Borroni B, Padovani A, Rossini PM, Binetti G.

J Neurol. 2007 Jan;254(1):107-9. Epub 2007 Feb 3. No abstract available. PMID: 17277912 [PubMed - indexed for MEDLINE]Related articles

Molecular markers of early Parkinson's disease based on gene expression in blood.

Scherzer CR, Eklund AC, Morse LJ, Liao Z, Locascio JJ, Fefer D, Schwarzschild MA, Schlossmacher MG, Hauser MA, Vance JM, Sudarsky LR, Standaert DG, Growdon JH, Jensen RV, Gullans SR.

Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):955-60. Epub 2007 Jan 10.PMID: 17215369 [PubMed - indexed for MEDLINE]Related articlesFree article

Herbicide exposure modifies GSTP1 haplotype association to Parkinson onset age: the GenePD Study.

Wilk JB, Tobin JE, Suchowersky O, Shill HA, Klein C, Wooten GF, Lew MF, Mark MH, Guttman M, Watts RL, Singer C, Growdon JH, Latourelle JC, Saint-Hilaire MH, DeStefano AL, Prakash R, Williamson S, Berg CJ, Sun M, Goldwurm S, Pezzoli G, Racette BA, Perlmutter JS, Parsian A, Baker KB, Giroux ML, Litvan I, Pramstaller PP, Nicholson G, Burn DJ, Chinnery PF, Vieregge P, Slevin JT, Cambi F, MacDonald ME, Gusella JF, Myers RH, Golbe LI.

Neurology. 2006 Dec 26;67(12):2206-10.PMID: 17190945 [PubMed - indexed for MEDLINE]Related articles

Prevalence and effects of lobar microhemorrhages in early-stage dementia.

Atri A, Locascio JJ, Lin JM, Yap L, Dickerson BC, Grodstein F, Irizarry MC, Growdon JH, Greenberg SM.

Neurodegener Dis. 2005;2(6):305-12.PMID: 16909013 [PubMed - indexed for MEDLINE]Related articles

Can the immune system fight Alzheimer disease?

Hyman BT, Growdon JH.

Nat Med. 2006 Jul;12(7):755-6; discussion 756. No abstract available. PMID: 16829929 [PubMed - indexed for MEDLINE]Related articles

No alteration in tau exon 10 alternative splicing in tangle-bearing neurons of the Alzheimer's disease brain.

Ingelsson M, Ramasamy K, Cantuti-Castelvetri I, Skoglund L, Matsui T, Orne J, Kowa H, Raju S, Vanderburg CR, Augustinack JC, de Silva R, Lees AJ, Lannfelt L, Growdon JH, Frosch MP, Standaert DG, Irizarry MC, Hyman BT.

Acta Neuropathol. 2006 Oct;112(4):439-49. Epub 2006 Jun 27.PMID: 16802167 [PubMed - indexed for MEDLINE]Related articles

Influence of heterozygosity for parkin mutation on onset age in familial Parkinson disease: the GenePD study.

Sun M, Latourelle JC, Wooten GF, Lew MF, Klein C, Shill HA, Golbe LI, Mark MH, Racette BA, Perlmutter JS, Parsian A, Guttman M, Nicholson G, Xu G, Wilk JB, Saint-Hilaire MH, DeStefano AL, Prakash R, Williamson S, Suchowersky O, Labelle N, Growdon JH, Singer C, Watts RL, Goldwurm S, Pezzoli G, Baker KB, Pramstaller PP, Burn DJ, Chinnery PF, Sherman S, Vieregge P, Litvan I, Gillis T, MacDonald ME, Myers RH, Gusella JF.

Arch Neurol. 2006 Jun;63(6):826-32.PMID: 16769863 [PubMed - indexed for MEDLINE]Related articlesFree article

Current pharmacotherapy for Alzheimer's disease.

Lleó A, Greenberg SM, Growdon JH.

Annu Rev Med. 2006;57:513-33. Review.PMID: 16409164 [PubMed - indexed for MEDLINE]Related articles

Plasma beta-amyloid and white matter lesions in AD, MCI, and cerebral amyloid angiopathy.

Gurol ME, Irizarry MC, Smith EE, Raju S, Diaz-Arrastia R, Bottiglieri T, Rosand J, Growdon JH, Greenberg SM.

Neurology. 2006 Jan 10;66(1):23-9.PMID: 16401840 [PubMed - indexed for MEDLINE]Related articles

Association of homocysteine with plasma amyloid beta protein in aging and neurodegenerative disease.

Irizarry MC, Gurol ME, Raju S, Diaz-Arrastia R, Locascio JJ, Tennis M, Hyman BT, Growdon JH, Greenberg SM, Bottiglieri T.

Neurology. 2005 Nov 8;65(9):1402-8.PMID: 16275827 [PubMed - indexed for MEDLINE]Related articles

Commentary on "Diagnosis of Alzheimer's disease: Two decades of progress." The NIA's Alzheimer Disease Centers.

Growdon JH.

Alzheimers Dement. 2005 Oct;1(2):101. No abstract available. PMID: 19595834 [PubMed - in process]Related articles

Frontotemporal dementia: impact of P301L tau mutation on a healthy carrier.

Alberici A, Gobbo C, Panzacchi A, Nicosia F, Ghidoni R, Benussi L, Hock C, Papassotiropoulos A, Liberini P, Growdon JH, Frisoni GB, Villa A, Zanetti O, Cappa S, Fazio F, Binetti G.

J Neurol Neurosurg Psychiatry. 2004 Nov;75(11):1607-10.PMID: 15489396 [PubMed - indexed for MEDLINE]Related articlesFree article

Early Abeta accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain.

Ingelsson M, Fukumoto H, Newell KL, Growdon JH, Hedley-Whyte ET, Frosch MP, Albert MS, Hyman BT, Irizarry MC.

Neurology. 2004 Mar 23;62(6):925-31.PMID: 15037694 [PubMed - indexed for MEDLINE]Related articles

Effects of Alzheimer disease on memory for verbal emotional information.

Kensinger EA, Anderson A, Growdon JH, Corkin S.

Neuropsychologia. 2004;42(6):791-800.PMID: 15037057 [PubMed - indexed for MEDLINE]Related articles

Clinical, pathological, and biochemical spectrum of Alzheimer disease associated with PS-1 mutations.

Lleó A, Berezovska O, Growdon JH, Hyman BT.

Am J Geriatr Psychiatry. 2004 Mar-Apr;12(2):146-56. Review.PMID: 15010344 [PubMed - indexed for MEDLINE]Related articles

Effects of normal aging and Alzheimer's disease on emotional memory.

Kensinger EA, Brierley B, Medford N, Growdon JH, Corkin S.

Emotion. 2002 Jun;2(2):118-34.PMID: 12899186 [PubMed - indexed for MEDLINE]Related articles

Age but not diagnosis is the main predictor of plasma amyloid beta-protein levels.

Fukumoto H, Tennis M, Locascio JJ, Hyman BT, Growdon JH, Irizarry MC.

Arch Neurol. 2003 Jul;60(7):958-64.PMID: 12873852 [PubMed - indexed for MEDLINE]Related articlesFree article

Working memory in mild Alzheimer's disease and early Parkinson's disease.

Kensinger EA, Shearer DK, Locascio JJ, Growdon JH, Corkin S.

Neuropsychology. 2003 Apr;17(2):230-9.PMID: 12803428 [PubMed - indexed for MEDLINE]Related articles

Selective reduction of soluble tau proteins in sporadic and familial frontotemporal dementias: an international follow-up study.

Zhukareva V, Sundarraj S, Mann D, Sjogren M, Blenow K, Clark CM, McKeel DW, Goate A, Lippa CF, Vonsattel JP, Growdon JH, Trojanowski JQ, Lee VM.

Acta Neuropathol. 2003 May;105(5):469-76. Epub 2003 Jan 25.PMID: 12677447 [PubMed - indexed for MEDLINE]Related articles

Relation between clinical characteristics of Parkinson's disease and cognitive decline.

Locascio JJ, Corkin S, Growdon JH.

J Clin Exp Neuropsychol. 2003 Feb;25(1):94-109.PMID: 12607175 [PubMed - indexed for MEDLINE]Related articles

Incorporating biomarkers into clinical drug trials in Alzheimer's disease.

Growdon JH.

J Alzheimers Dis. 2001 Jun;3(3):287-292.PMID: 12214049 [PubMed - as supplied by publisher]Related articles

PARK3 influences age at onset in Parkinson disease: a genome scan in the GenePD study.

DeStefano AL, Lew MF, Golbe LI, Mark MH, Lazzarini AM, Guttman M, Montgomery E, Waters CH, Singer C, Watts RL, Currie LJ, Wooten GF, Maher NE, Wilk JB, Sullivan KM, Slater KM, Saint-Hilaire MH, Feldman RG, Suchowersky O, Lafontaine AL, Labelle N, Growdon JH, Vieregge P, Pramstaller PP, Klein C, Hubble JP, Reider CR, Stacy M, MacDonald ME, Gusella JF, Myers RH.

Am J Hum Genet. 2002 May;70(5):1089-95. Epub 2002 Mar 27.PMID: 11920285 [PubMed - indexed for MEDLINE]Related articlesFree article

Diagnosing dementia with Lewy bodies.

Pompeu F, Growdon JH.

Arch Neurol. 2002 Jan;59(1):29-30. No abstract available. PMID: 11790227 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide scan for Parkinson's disease: the GenePD Study.

DeStefano AL, Golbe LI, Mark MH, Lazzarini AM, Maher NE, Saint-Hilaire M, Feldman RG, Guttman M, Watts RL, Suchowersky O, Lafontaine AL, Labelle N, Lew MF, Waters CH, Growdon JH, Singer C, Currie LJ, Wooten GF, Vieregge P, Pramstaller PP, Klein C, Hubble JP, Stacy M, Montgomery E, MacDonald ME, Gusella JF, Myers RH.

Neurology. 2001 Sep 25;57(6):1124-6.PMID: 11571351 [PubMed - indexed for MEDLINE]Related articles

Elevation of cystatin C in susceptible neurons in Alzheimer's disease.

Deng A, Irizarry MC, Nitsch RM, Growdon JH, Rebeck GW.

Am J Pathol. 2001 Sep;159(3):1061-8.PMID: 11549598 [PubMed - indexed for MEDLINE]Related articlesFree article

Treatment with the selective muscarinic agonist talsaclidine decreases cerebrospinal fluid levels of total amyloid beta-peptide in patients with Alzheimer's disease.

Hock C, Maddalena A, Heuser I, Naber D, Oertel W, von der Kammer H, Wienrich M, Raschig A, Deng M, Growdon JH, Nitsch RM.

Ann N Y Acad Sci. 2000;920:285-91.PMID: 11193166 [PubMed - indexed for MEDLINE]Related articles

The selective muscarinic M1 agonist AF102B decreases levels of total Abeta in cerebrospinal fluid of patients with Alzheimer's disease.

Nitsch RM, Deng M, Tennis M, Schoenfeld D, Growdon JH.

Ann Neurol. 2000 Dec;48(6):913-8.PMID: 11117548 [PubMed - indexed for MEDLINE]Related articles

Genetic association of a cystatin C gene polymorphism with late-onset Alzheimer disease.

Finckh U, von der Kammer H, Velden J, Michel T, Andresen B, Deng A, Zhang J, Müller-Thomsen T, Zuchowski K, Menzer G, Mann U, Papassotiropoulos A, Heun R, Zurdel J, Holst F, Benussi L, Stoppe G, Reiss J, Miserez AR, Staehelin HB, Rebeck GW, Hyman BT, Binetti G, Hock C, Growdon JH, Nitsch RM.

Arch Neurol. 2000 Nov;57(11):1579-83.PMID: 11074789 [PubMed - indexed for MEDLINE]Related articlesFree article

Clozapine and risperidone treatment of psychosis in Parkinson's disease.

Ellis T, Cudkowicz ME, Sexton PM, Growdon JH.

J Neuropsychiatry Clin Neurosci. 2000 Summer;12(3):364-9.PMID: 10956570 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of proximal and distal muscles' groups contraction and mental stress on the amplitude and frequency of physiological finger tremor. An accelerometric study.

Growdon W, Ghika J, Henderson J, van Melle G, Regli F, Bogousslavsky J, Growdon JH.

Electromyogr Clin Neurophysiol. 2000 Jul-Aug;40(5):295-303.PMID: 10938996 [PubMed - indexed for MEDLINE]Related articles

Head injury and the risk of AD in the MIRAGE study.

Guo Z, Cupples LA, Kurz A, Auerbach SH, Volicer L, Chui H, Green RC, Sadovnick AD, Duara R, DeCarli C, Johnson K, Go RC, Growdon JH, Haines JL, Kukull WA, Farrer LA.

Neurology. 2000 Mar 28;54(6):1316-23.PMID: 10746604 [PubMed - indexed for MEDLINE]Related articles

Differences between Pick disease and Alzheimer disease in clinical appearance and rate of cognitive decline.

Binetti G, Locascio JJ, Corkin S, Vonsattel JP, Growdon JH.

Arch Neurol. 2000 Feb;57(2):225-32.PMID: 10681082 [PubMed - indexed for MEDLINE]Related articlesFree article