PubMed

DNA adducts of aristolochic acid II: total synthesis and site-specific mutagenesis studies in mammalian cells.

Attaluri S, Bonala RR, Yang IY, Lukin MA, Wen Y, Grollman AP, Moriya M, Iden CR, Johnson F.

Nucleic Acids Res. 2009 Oct 23. [Epub ahead of print]PMID: 19854934 [PubMed - as supplied by publisher]Related articlesFree article

Substrate specificity and excision kinetics of natural polymorphic variants and phosphomimetic mutants of human 8-oxoguanine-DNA glycosylase.

Sidorenko VS, Grollman AP, Jaruga P, Dizdaroglu M, Zharkov DO.

FEBS J. 2009 Sep;276(18):5149-62. Epub 2009 Aug 7.PMID: 19674107 [PubMed - indexed for MEDLINE]Related articles

Transplantation for Chinese herb nephropathy.

Morrissey PE, Gautam A, Yang A, Grollman AP, Esparza A, Gohh RY, Monaco AP.

Clin Transpl. 2006:560. No abstract available. PMID: 18365433 [PubMed - indexed for MEDLINE]Related articles

Molecular simulations reveal a common binding mode for glycosylase binding of oxidatively damaged DNA lesions.

Song K, Kelso C, de los Santos C, Grollman AP, Simmerling C.

J Am Chem Soc. 2007 Nov 28;129(47):14536-7. Epub 2007 Nov 8.PMID: 17988127 [PubMed - indexed for MEDLINE]Related articles

Limitations of "evidence-based indications" for herbs.

Marcus DM, Grollman AP.

Mayo Clin Proc. 2007 Nov;82(11):1433; author reply 1433-4. No abstract available. PMID: 17976363 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of environmental toxins in endemic (Balkan) nephropathy. October 2006, Zagreb, Croatia.

Grollman AP, Jelaković B.

J Am Soc Nephrol. 2007 Nov;18(11):2817-23. Epub 2007 Oct 17.PMID: 17942951 [PubMed - indexed for MEDLINE]Related articlesFree article

Aristolochic acid and the etiology of endemic (Balkan) nephropathy.

Grollman AP, Shibutani S, Moriya M, Miller F, Wu L, Moll U, Suzuki N, Fernandes A, Rosenquist T, Medverec Z, Jakovina K, Brdar B, Slade N, Turesky RJ, Goodenough AK, Rieger R, Vukelić M, Jelaković B.

Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12129-34. Epub 2007 Jul 9.PMID: 17620607 [PubMed - indexed for MEDLINE]Related articlesFree article

Chromatin structure regulation in transforming growth factor-beta-directed epithelial-mesenchymal transition.

Blumenberg M, Gao S, Dickman K, Grollman AP, Bottinger EP, Zavadil J.

Cells Tissues Organs. 2007;185(1-3):162-74. Review.PMID: 17587822 [PubMed - indexed for MEDLINE]Related articles

Molecular mechanics parameters for the FapydG DNA lesion.

Song K, Hornak V, de los Santos C, Grollman AP, Simmerling C.

J Comput Chem. 2008 Jan 15;29(1):17-23.PMID: 17551974 [PubMed - indexed for MEDLINE]Related articles

Selective toxicity of aristolochic acids I and II.

Shibutani S, Dong H, Suzuki N, Ueda S, Miller F, Grollman AP.

Drug Metab Dispos. 2007 Jul;35(7):1217-22. Epub 2007 Mar 28.PMID: 17392392 [PubMed - indexed for MEDLINE]Related articlesFree article

Catalytic mechanism of Escherichia coli endonuclease VIII: roles of the intercalation loop and the zinc finger.

Kropachev KY, Zharkov DO, Grollman AP.

Biochemistry. 2006 Oct 3;45(39):12039-49.PMID: 17002303 [PubMed - indexed for MEDLINE]Related articlesFree article

Computational analysis of the mode of binding of 8-oxoguanine to formamidopyrimidine-DNA glycosylase.

Song K, Hornak V, de Los Santos C, Grollman AP, Simmerling C.

Biochemistry. 2006 Sep 12;45(36):10886-94.PMID: 16953574 [PubMed - indexed for MEDLINE]Related articles

Structure of T4 pyrimidine dimer glycosylase in a reduced imine covalent complex with abasic site-containing DNA.

Golan G, Zharkov DO, Grollman AP, Dodson ML, McCullough AK, Lloyd RS, Shoham G.

J Mol Biol. 2006 Sep 15;362(2):241-58. Epub 2006 Jul 7.PMID: 16916523 [PubMed - indexed for MEDLINE]Related articles

Science and government. Review for NCCAM is overdue.

Marcus DM, Grollman AP.

Science. 2006 Jul 21;313(5785):301-2. No abstract available. PMID: 16857923 [PubMed - indexed for MEDLINE]Related articles

RNA aptamers selected against DNA polymerase beta inhibit the polymerase activities of DNA polymerases beta and kappa.

Gening LV, Klincheva SA, Reshetnjak A, Grollman AP, Miller H.

Nucleic Acids Res. 2006 May 17;34(9):2579-86. Print 2006.PMID: 16707660 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative determination of aristolochic acid-derived DNA adducts in rats using 32P-postlabeling/polyacrylamide gel electrophoresis analysis.

Dong H, Suzuki N, Torres MC, Bonala RR, Johnson F, Grollman AP, Shibutani S.

Drug Metab Dispos. 2006 Jul;34(7):1122-7. Epub 2006 Apr 12.PMID: 16611860 [PubMed - indexed for MEDLINE]Related articlesFree article

Proteomic approach to identification of proteins reactive for abasic sites in DNA.

Rieger RA, Zaika EI, Xie W, Johnson F, Grollman AP, Iden CR, Zharkov DO.

Mol Cell Proteomics. 2006 May;5(5):858-67. Epub 2006 Feb 11.PMID: 16474175 [PubMed - indexed for MEDLINE]Related articlesFree article

Dynamic behavior of DNA base pairs containing 8-oxoguanine.

Cheng X, Kelso C, Hornak V, de los Santos C, Grollman AP, Simmerling C.

J Am Chem Soc. 2005 Oct 12;127(40):13906-18.PMID: 16201812 [PubMed - indexed for MEDLINE]Related articles

Structure of the uncomplexed DNA repair enzyme endonuclease VIII indicates significant interdomain flexibility.

Golan G, Zharkov DO, Feinberg H, Fernandes AS, Zaika EI, Kycia JH, Grollman AP, Shoham G.

Nucleic Acids Res. 2005 Sep 6;33(15):5006-16. Print 2005.PMID: 16145054 [PubMed - indexed for MEDLINE]Related articlesFree article

Academic perspectives on dietary supplements use: the need for new guidelines.

Grollman AP.

Thromb Res. 2005;117(1-2):185-92; discussion 201-7. Epub 2005 Sep 6. No abstract available. PMID: 16143370 [PubMed - indexed for MEDLINE]Related articles

The DNA trackwalkers: principles of lesion search and recognition by DNA glycosylases.

Zharkov DO, Grollman AP.

Mutat Res. 2005 Sep 4;577(1-2):24-54. Review.PMID: 15939442 [PubMed - indexed for MEDLINE]Related articles

Mutagenic specificity of 2-acetylaminonaphthalene-derived DNA adduct in mammalian cells.

Tan X, Bonala RR, Suzuki N, Johnson F, Grollman AP, Shibutani S.

Chem Biol Interact. 2005 Apr 15;152(2-3):131-8.PMID: 15840386 [PubMed - indexed for MEDLINE]Related articles

Endemic nephropathy: the case for chronic poisoning by aristolochia.

Hranjec T, Kovac A, Kos J, Mao W, Chen JJ, Grollman AP, Jelaković B.

Croat Med J. 2005 Feb;46(1):116-25.PMID: 15726685 [PubMed - indexed for MEDLINE]Related articlesFree article

Substrate discrimination by formamidopyrimidine-DNA glycosylase: distinguishing interactions within the active site.

Perlow-Poehnelt RA, Zharkov DO, Grollman AP, Broyde S.

Biochemistry. 2004 Dec 28;43(51):16092-105.PMID: 15610004 [PubMed - indexed for MEDLINE]Related articles

Mechanism of frameshift (deletion) generated by acetylaminofluorene-derived DNA adducts in vitro.

Shibutani S, Suzuki N, Grollman AP.

Biochemistry. 2004 Dec 21;43(50):15929-35.PMID: 15595849 [PubMed - indexed for MEDLINE]Related articles

Mutagenic potential of benzo[a]pyrene-derived DNA adducts positioned in codon 273 of the human P53 gene.

Dong H, Bonala RR, Suzuki N, Johnson F, Grollman AP, Shibutani S.

Biochemistry. 2004 Dec 21;43(50):15922-8.PMID: 15595848 [PubMed - indexed for MEDLINE]Related articles

Mutagenic properties of 3-(deoxyguanosin-N2-yl)-2-acetylaminofluorene, a persistent acetylaminofluorene-derived DNA adduct in mammalian cells.

Yasui M, Dong H, Bonala RR, Suzuki N, Ohmori H, Hanaoka F, Johnson F, Grollman AP, Shibutani S.

Biochemistry. 2004 Nov 30;43(47):15005-13.PMID: 15554708 [PubMed - indexed for MEDLINE]Related articles

'Knock down' of DNA polymerase beta by RNA interference: recapitulation of null phenotype.

Polosina YY, Rosenquist TA, Grollman AP, Miller H.

DNA Repair (Amst). 2004 Nov 2;3(11):1469-74.PMID: 15380102 [PubMed - indexed for MEDLINE]Related articles

Crystallization and preliminary crystallographic analysis of endonuclease VIII in its uncomplexed form.

Golan G, Zharkov DO, Fernandes AS, Zaika E, Kycia JH, Wawrzak Z, Grollman AP, Shoham G.

Acta Crystallogr D Biol Crystallogr. 2004 Aug;60(Pt 8):1476-80. Epub 2004 Jul 21.PMID: 15272182 [PubMed - indexed for MEDLINE]Related articles

Lesion (in)tolerance reveals insights into DNA replication fidelity.

Freisinger E, Grollman AP, Miller H, Kisker C.

EMBO J. 2004 Apr 7;23(7):1494-505. Epub 2004 Apr 1.PMID: 15057282 [PubMed - indexed for MEDLINE]Related articlesFree article

Stereoselective excision of thymine glycol from oxidatively damaged DNA.

Miller H, Fernandes AS, Zaika E, McTigue MM, Torres MC, Wente M, Iden CR, Grollman AP.

Nucleic Acids Res. 2004 Jan 15;32(1):338-45. Print 2004.PMID: 14726482 [PubMed - indexed for MEDLINE]Related articlesFree article

The thermodynamics of template-directed DNA synthesis: base insertion and extension enthalpies.

Minetti CA, Remeta DP, Miller H, Gelfand CA, Plum GE, Grollman AP, Breslauer KJ.

Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):14719-24. Epub 2003 Nov 17.PMID: 14623953 [PubMed - indexed for MEDLINE]Related articlesFree article

Substrate discrimination by formamidopyrimidine-DNA glycosylase: a mutational analysis.

Zaika EI, Perlow RA, Matz E, Broyde S, Gilboa R, Grollman AP, Zharkov DO.

J Biol Chem. 2004 Feb 6;279(6):4849-61. Epub 2003 Nov 7.PMID: 14607836 [PubMed - indexed for MEDLINE]Related articlesFree article

Ephedra-free is not danger-free.

Marcus DM, Grollman AP.

Science. 2003 Sep 19;301(5640):1669-71; author reply 1669-71. No abstract available. PMID: 14500960 [PubMed - indexed for MEDLINE]Related articles

Identification of tamoxifen-DNA adducts in monkeys treated with tamoxifen.

Shibutani S, Suzuki N, Laxmi YR, Schild LJ, Divi RL, Grollman AP, Poirier MC.

Cancer Res. 2003 Aug 1;63(15):4402-6.PMID: 12907611 [PubMed - indexed for MEDLINE]Related articlesFree article

Structural characterization of the Fpg family of DNA glycosylases.

Zharkov DO, Shoham G, Grollman AP.

DNA Repair (Amst). 2003 Aug 12;2(8):839-62. Review.PMID: 12893082 [PubMed - indexed for MEDLINE]Related articles

Crystallographic characterization of an exocyclic DNA adduct: 3,N4-etheno-2'-deoxycytidine in the dodecamer 5'-CGCGAATTepsilonCGCG-3'.

Freisinger E, Fernandes A, Grollman AP, Kisker C.

J Mol Biol. 2003 Jun 13;329(4):685-97.PMID: 12787670 [PubMed - indexed for MEDLINE]Related articles

DNA repair investigations using siRNA.

Miller H, Grollman AP.

DNA Repair (Amst). 2003 Jun 11;2(6):759-63.PMID: 12767354 [PubMed - indexed for MEDLINE]Related articles

Energetics of lesion recognition by a DNA repair protein: thermodynamic characterization of formamidopyrimidine-glycosylase (Fpg) interactions with damaged DNA duplexes.

Minetti CA, Remeta DP, Zharkov DO, Plum GE, Johnson F, Grollman AP, Breslauer KJ.

J Mol Biol. 2003 May 16;328(5):1047-60.PMID: 12729740 [PubMed - indexed for MEDLINE]Related articles

The novel DNA glycosylase, NEIL1, protects mammalian cells from radiation-mediated cell death.

Rosenquist TA, Zaika E, Fernandes AS, Zharkov DO, Miller H, Grollman AP.

DNA Repair (Amst). 2003 May 13;2(5):581-91.PMID: 12713815 [PubMed - indexed for MEDLINE]Related articles

Structure of DNA polymerase beta with the mutagenic DNA lesion 8-oxodeoxyguanine reveals structural insights into its coding potential.

Krahn JM, Beard WA, Miller H, Grollman AP, Wilson SH.

Structure. 2003 Jan;11(1):121-7.PMID: 12517346 [PubMed - indexed for MEDLINE]Related articles

Botanical medicines--the need for new regulations.

Marcus DM, Grollman AP.

N Engl J Med. 2002 Dec 19;347(25):2073-6. No abstract available. PMID: 12490692 [PubMed - indexed for MEDLINE]Related articles

Mutagenic events in Escherichia coli and mammalian cells generated in response to acetylaminofluorene-derived DNA adducts positioned in the Nar I restriction enzyme site.

Tan X, Suzuki N, Grollman AP, Shibutani S.

Biochemistry. 2002 Dec 3;41(48):14255-62.PMID: 12450390 [PubMed - indexed for MEDLINE]Related articles

Combining structural and bioinformatics methods for the analysis of functionally important residues in DNA glycosylases.

Zharkov DO, Grollman AP.

Free Radic Biol Med. 2002 Jun 15;32(12):1254-63. Review.PMID: 12057763 [PubMed - indexed for MEDLINE]Related articles

Translesion synthesis by human DNA polymerase kappa on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-N(2)-BPDE (7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene).

Suzuki N, Ohashi E, Kolbanovskiy A, Geacintov NE, Grollman AP, Ohmori H, Shibutani S.

Biochemistry. 2002 May 14;41(19):6100-6.PMID: 11994005 [PubMed - indexed for MEDLINE]Related articles

Structure of formamidopyrimidine-DNA glycosylase covalently complexed to DNA.

Gilboa R, Zharkov DO, Golan G, Fernandes AS, Gerchman SE, Matz E, Kycia JH, Grollman AP, Shoham G.

J Biol Chem. 2002 May 31;277(22):19811-6. Epub 2002 Mar 23.PMID: 11912217 [PubMed - indexed for MEDLINE]Related articlesFree article

Genotoxic mechanism for the major acrolein-derived deoxyguanosine adduct in human cells.

Yang IY, Johnson F, Grollman AP, Moriya M.

Chem Res Toxicol. 2002 Feb;15(2):160-4.PMID: 11849041 [PubMed - indexed for MEDLINE]Related articles

Structural analysis of an Escherichia coli endonuclease VIII covalent reaction intermediate.

Zharkov DO, Golan G, Gilboa R, Fernandes AS, Gerchman SE, Kycia JH, Rieger RA, Grollman AP, Shoham G.

EMBO J. 2002 Feb 15;21(4):789-800.PMID: 11847126 [PubMed - indexed for MEDLINE]Related articlesFree article

Translesional synthesis past acetylaminofluorene-derived DNA adducts catalyzed by human DNA polymerase kappa and Escherichia coli DNA polymerase IV.

Suzuki N, Ohashi E, Hayashi K, Ohmori H, Grollman AP, Shibutani S.

Biochemistry. 2001 Dec 18;40(50):15176-83.PMID: 11735400 [PubMed - indexed for MEDLINE]Related articles

Translesion DNA synthesis catalyzed by human pol eta and pol kappa across 1,N6-ethenodeoxyadenosine.

Levine RL, Miller H, Grollman A, Ohashi E, Ohmori H, Masutani C, Hanaoka F, Moriya M.

J Biol Chem. 2001 Jun 1;276(22):18717-21. Epub 2001 Mar 16.PMID: 11376002 [PubMed - indexed for MEDLINE]Related articlesFree article