PubMed

Thyroid Hormone Induced Brown Adipose Tissue and Amelioration of Diabetes in a Patient with Extreme Insulin Resistance.

Skarulis MC, Celi FS, Mueller E, Zemskova M, Malek R, Hugendubler L, Cochran C, Solomon J, Chen C, Gorden P.

J Clin Endocrinol Metab. 2009 Nov 6. [Epub ahead of print]PMID: 19897683 [PubMed - as supplied by publisher]Related articles

Insulinoma.

Mathur A, Gorden P, Libutti SK.

Surg Clin North Am. 2009 Oct;89(5):1105-21.PMID: 19836487 [PubMed - in process]Related articles

Efficacy of leptin therapy in the different forms of human lipodystrophy.

Chong AY, Lupsa BC, Cochran EK, Gorden P.

Diabetologia. 2009 Sep 2. [Epub ahead of print]PMID: 19727665 [PubMed - as supplied by publisher]Related articles

Autoimmune forms of hypoglycemia.

Lupsa BC, Chong AY, Cochran EK, Soos MA, Semple RK, Gorden P.

Medicine (Baltimore). 2009 May;88(3):141-53. Review.PMID: 19440117 [PubMed - indexed for MEDLINE]Related articles

Localization of insulinomas to regions of the pancreas by intraarterial calcium stimulation: the NIH experience.

Guettier JM, Kam A, Chang R, Skarulis MC, Cochran C, Alexander HR, Libutti SK, Pingpank JF, Gorden P.

J Clin Endocrinol Metab. 2009 Apr;94(4):1074-80. Epub 2009 Feb 3.PMID: 19190102 [PubMed - indexed for MEDLINE]Related articles

Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis.

Semple RK, Sleigh A, Murgatroyd PR, Adams CA, Bluck L, Jackson S, Vottero A, Kanabar D, Charlton-Menys V, Durrington P, Soos MA, Carpenter TA, Lomas DJ, Cochran EK, Gorden P, O'Rahilly S, Savage DB.

J Clin Invest. 2009 Feb;119(2):315-22. doi: 10.1172/JCI37432. Epub 2009 Jan 26.PMID: 19164855 [PubMed - indexed for MEDLINE]Related articlesFree article

Complement abnormalities in acquired lipodystrophy revisited.

Savage DB, Semple RK, Clatworthy MR, Lyons PA, Morgan BP, Cochran EK, Gorden P, Raymond-Barker P, Murgatroyd PR, Adams C, Scobie I, Mufti GJ, Alexander GJ, Thiru S, Murano I, Cinti S, Chaudhry AN, Smith KG, O'Rahilly S.

J Clin Endocrinol Metab. 2009 Jan;94(1):10-6. Epub 2008 Oct 14.PMID: 18854390 [PubMed - indexed for MEDLINE]Related articles

Effect of depot medroxyprogesterone acetate on glucose tolerance in generalized lipodystrophy.

Yauger BJ, Gorden P, Park J, Cochran E, Stratton P.

Obstet Gynecol. 2008 Aug;112(2 Pt 2):445-7.PMID: 18669758 [PubMed - indexed for MEDLINE]Related articles

Plasma adiponectin as a marker of insulin receptor dysfunction: clinical utility in severe insulin resistance.

Semple RK, Cochran EK, Soos MA, Burling KA, Savage DB, Gorden P, O'Rahilly S.

Diabetes Care. 2008 May;31(5):977-9. Epub 2008 Feb 25.PMID: 18299442 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulinoma and gastrinoma syndromes from a single intrapancreatic neuroendocrine tumor.

Lodish MB, Powell AC, Abu-Asab M, Cochran C, Lenz P, Libutti SK, Pingpank JF, Tsokos M, Gorden P.

J Clin Endocrinol Metab. 2008 Apr;93(4):1123-8. Epub 2008 Feb 5.PMID: 18252785 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptin therapy for partial lipodystrophy linked to a PPAR-gamma mutation.

Guettier JM, Park JY, Cochran EK, Poitou C, Basdevant A, Meier M, Clément K, Magré J, Gorden P.

Clin Endocrinol (Oxf). 2008 Apr;68(4):547-54. Epub 2007 Dec 10.PMID: 18076675 [PubMed - indexed for MEDLINE]Related articlesFree article

Type 1 diabetes associated with acquired generalized lipodystrophy and insulin resistance: the effect of long-term leptin therapy.

Park JY, Chong AY, Cochran EK, Kleiner DE, Haller MJ, Schatz DA, Gorden P.

J Clin Endocrinol Metab. 2008 Jan;93(1):26-31. Epub 2007 Oct 16.PMID: 17940115 [PubMed - indexed for MEDLINE]Related articlesFree article

Spectrum of renal diseases associated with extreme forms of insulin resistance.

Musso C, Javor E, Cochran E, Balow JE, Gorden P.

Clin J Am Soc Nephrol. 2006 Jul;1(4):616-22. Epub 2006 Apr 26. Review.PMID: 17699267 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term efficacy of leptin replacement in patients with Dunnigan-type familial partial lipodystrophy.

Park JY, Javor ED, Cochran EK, DePaoli AM, Gorden P.

Metabolism. 2007 Apr;56(4):508-16.PMID: 17379009 [PubMed - indexed for MEDLINE]Related articlesFree article

Paradoxical elevation of high-molecular weight adiponectin in acquired extreme insulin resistance due to insulin receptor antibodies.

Semple RK, Halberg NH, Burling K, Soos MA, Schraw T, Luan J, Cochran EK, Dunger DB, Wareham NJ, Scherer PE, Gorden P, O'Rahilly S.

Diabetes. 2007 Jun;56(6):1712-7. Epub 2007 Feb 26.PMID: 17325257 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypoglycemia.

Guettier JM, Gorden P.

Endocrinol Metab Clin North Am. 2006 Dec;35(4):753-66, viii-ix. Review.PMID: 17127144 [PubMed - indexed for MEDLINE]Related articles

The clinical efficacy of the adipocyte-derived hormone leptin in metabolic dysfunction.

Gorden P, Park JY.

Arch Physiol Biochem. 2006 Apr;112(2):114-8. Review.PMID: 16931453 [PubMed - indexed for MEDLINE]Related articles

Elevated plasma adiponectin in humans with genetically defective insulin receptors.

Semple RK, Soos MA, Luan J, Mitchell CS, Wilson JC, Gurnell M, Cochran EK, Gorden P, Chatterjee VK, Wareham NJ, O'Rahilly S.

J Clin Endocrinol Metab. 2006 Aug;91(8):3219-23. Epub 2006 May 16.PMID: 16705075 [PubMed - indexed for MEDLINE]Related articlesFree article

The clinical utility of leptin therapy in metabolic dysfunction.

Park JY, Gavrilova O, Gorden P.

Minerva Endocrinol. 2006 Jun;31(2):125-31. Review.PMID: 16682936 [PubMed - indexed for MEDLINE]Related articles

A prospective evaluation of laparoscopic exploration with intraoperative ultrasound as a technique for localizing sporadic insulinomas.

Grover AC, Skarulis M, Alexander HR, Pingpank JF, Javor ED, Chang R, Shawker T, Gorden P, Cochran C, Libutti SK.

Surgery. 2005 Dec;138(6):1003-8; discussion 1008.PMID: 16360384 [PubMed - indexed for MEDLINE]Related articles

Leptin replacement therapy modulates circulating lymphocyte subsets and cytokine responsiveness in severe lipodystrophy.

Oral EA, Javor ED, Ding L, Uzel G, Cochran EK, Young JR, DePaoli AM, Holland SM, Gorden P.

J Clin Endocrinol Metab. 2006 Feb;91(2):621-8. Epub 2005 Nov 29.PMID: 16317060 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term efficacy of leptin replacement in patients with generalized lipodystrophy.

Javor ED, Cochran EK, Musso C, Young JR, Depaoli AM, Gorden P.

Diabetes. 2005 Jul;54(7):1994-2002.PMID: 15983199 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical evidence that hyperinsulinaemia independent of gonadotropins stimulates ovarian growth.

Musso C, Shawker T, Cochran E, Javor ED, Young J, Gorden P.

Clin Endocrinol (Oxf). 2005 Jul;63(1):73-8.PMID: 15963065 [PubMed - indexed for MEDLINE]Related articles

Malignant insulinoma: spectrum of unusual clinical features.

Hirshberg B, Cochran C, Skarulis MC, Libutti SK, Alexander HR, Wood BJ, Chang R, Kleiner DE, Gorden P.

Cancer. 2005 Jul 15;104(2):264-72. Review.PMID: 15937909 [PubMed - indexed for MEDLINE]Related articlesFree article

The impact of evidence-based medicine on diabetes therapy.

Gorden P, Musso C.

Curr Diab Rep. 2005 Jun;5(3):157-9. Review. No abstract available. PMID: 15929859 [PubMed - indexed for MEDLINE]Related articles

The use of U-500 in patients with extreme insulin resistance.

Cochran E, Musso C, Gorden P.

Diabetes Care. 2005 May;28(5):1240-4. Review. No abstract available. Erratum in: Diabetes Care. 2007 Apr;30(4):1035. PMID: 15855601 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptin reverses nonalcoholic steatohepatitis in patients with severe lipodystrophy.

Javor ED, Ghany MG, Cochran EK, Oral EA, DePaoli AM, Premkumar A, Kleiner DE, Gorden P.

Hepatology. 2005 Apr;41(4):753-60.PMID: 15791619 [PubMed - indexed for MEDLINE]Related articles

The role of thecal androgen production in the regulation of estradiol biosynthesis by dominant bovine follicles during the first follicular wave.

Valdez KE, Cuneo SP, Gorden PJ, Turzillo AM.

J Anim Sci. 2005 Mar;83(3):597-603.PMID: 15705756 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin resistance, acanthosis nigricans, and hypertriglyceridemia.

Eberting CL, Javor E, Gorden P, Turner ML, Cowen EW.

J Am Acad Dermatol. 2005 Feb;52(2):341-4. No abstract available. PMID: 15692481 [PubMed - indexed for MEDLINE]Related articles

The long-term effect of recombinant methionyl human leptin therapy on hyperandrogenism and menstrual function in female and pituitary function in male and female hypoleptinemic lipodystrophic patients.

Musso C, Cochran E, Javor E, Young J, Depaoli AM, Gorden P.

Metabolism. 2005 Feb;54(2):255-63.PMID: 15690321 [PubMed - indexed for MEDLINE]Related articles

Proteinuric nephropathy in acquired and congenital generalized lipodystrophy: baseline characteristics and course during recombinant leptin therapy.

Javor ED, Moran SA, Young JR, Cochran EK, DePaoli AM, Oral EA, Turman MA, Blackett PR, Savage DB, O'Rahilly S, Balow JE, Gorden P.

J Clin Endocrinol Metab. 2004 Jul;89(7):3199-207.PMID: 15240593 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical course of genetic diseases of the insulin receptor (type A and Rabson-Mendenhall syndromes): a 30-year prospective.

Musso C, Cochran E, Moran SA, Skarulis MC, Oral EA, Taylor S, Gorden P.

Medicine (Baltimore). 2004 Jul;83(4):209-22. Review.PMID: 15232309 [PubMed - indexed for MEDLINE]Related articles

Efficacy of recombinant methionyl human leptin therapy for the extreme insulin resistance of the Rabson-Mendenhall syndrome.

Cochran E, Young JR, Sebring N, DePaoli A, Oral EA, Gorden P.

J Clin Endocrinol Metab. 2004 Apr;89(4):1548-54.PMID: 15070911 [PubMed - indexed for MEDLINE]Related articlesFree article

Changes in body composition in patients with severe lipodystrophy after leptin replacement therapy.

Moran SA, Patten N, Young JR, Cochran E, Sebring N, Reynolds J, Premkumar A, Depaoli AM, Skarulis MC, Oral EA, Gorden P.

Metabolism. 2004 Apr;53(4):513-9.PMID: 15045701 [PubMed - indexed for MEDLINE]Related articles

Successful renal transplantation in a patient with congenital generalized lipodystrophy: a case report.

McNally M, Mannon RB, Javor ED, Swanson SJ, Hale DA, Gorden P, Kirk AD.

Am J Transplant. 2004 Mar;4(3):447-9. No abstract available. PMID: 14962001 [PubMed - indexed for MEDLINE]Related articles

Peak stimulated insulin secretion is associated with specific changes in gene expression profiles in sporadic insulinomas.

Kayton ML, Costouros NG, Lorang D, Alexander HR, Hewitt SM, Cochran C, Shalev A, Harlan D, Skarulis MC, Gorden P, Libutti SK.

Surgery. 2003 Dec;134(6):982-7; discussion 987-8.PMID: 14668731 [PubMed - indexed for MEDLINE]Related articles

The clinical uses of leptin.

Gorden P, Gavrilova O.

Curr Opin Pharmacol. 2003 Dec;3(6):655-9. Review.PMID: 14644019 [PubMed - indexed for MEDLINE]Related articles

Phenotypic and genetic heterogeneity in congenital generalized lipodystrophy.

Agarwal AK, Simha V, Oral EA, Moran SA, Gorden P, O'Rahilly S, Zaidi Z, Gurakan F, Arslanian SA, Klar A, Ricker A, White NH, Bindl L, Herbst K, Kennel K, Patel SB, Al-Gazali L, Garg A.

J Clin Endocrinol Metab. 2003 Oct;88(10):4840-7.PMID: 14557463 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of leptin replacement on pituitary hormone regulation in patients with severe lipodystrophy.

Oral EA, Ruiz E, Andewelt A, Sebring N, Wagner AJ, Depaoli AM, Gorden P.

J Clin Endocrinol Metab. 2002 Jul;87(7):3110-7.PMID: 12107209 [PubMed - indexed for MEDLINE]Related articlesFree article

Blind distal pancreatectomy for occult insulinoma, an inadvisable procedure.

Hirshberg B, Libutti SK, Alexander HR, Bartlett DL, Cochran C, Livi A, Chang R, Shawker T, Skarulis MC, Gorden P.

J Am Coll Surg. 2002 Jun;194(6):761-4.PMID: 12081066 [PubMed - indexed for MEDLINE]Related articles

John P. Peters: his role in diabetes, research, and patient care.

Gorden P.

Yale J Biol Med. 2002 Jan-Feb;75(1):13-7. No abstract available. PMID: 12074475 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy.

Petersen KF, Oral EA, Dufour S, Befroy D, Ariyan C, Yu C, Cline GW, DePaoli AM, Taylor SI, Gorden P, Shulman GI.

J Clin Invest. 2002 May;109(10):1345-50.PMID: 12021250 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical course of the syndrome of autoantibodies to the insulin receptor (type B insulin resistance): a 28-year perspective.

Arioglu E, Andewelt A, Diabo C, Bell M, Taylor SI, Gorden P.

Medicine (Baltimore). 2002 Mar;81(2):87-100. No abstract available. PMID: 11889410 [PubMed - indexed for MEDLINE]Related articles

Leptin-replacement therapy for lipodystrophy.

Oral EA, Simha V, Ruiz E, Andewelt A, Premkumar A, Snell P, Wagner AJ, DePaoli AM, Reitman ML, Taylor SI, Gorden P, Garg A.

N Engl J Med. 2002 Feb 21;346(8):570-8.PMID: 11856796 [PubMed - indexed for MEDLINE]Related articlesFree article

Intensive, long-term plasma exchange therapy for severe hypertriglyceridemia in acquired generalized lipoatrophy.

Bolan C, Oral EA, Gorden P, Taylor S, Leitman SF.

J Clin Endocrinol Metab. 2002 Jan;87(1):380-4.PMID: 11788680 [PubMed - indexed for MEDLINE]Related articlesFree article

Repaglinide-induced factitious hypoglycemia.

Hirshberg B, Skarulis MC, Pucino F, Csako G, Brennan R, Gorden P.

J Clin Endocrinol Metab. 2001 Feb;86(2):475-7.PMID: 11157993 [PubMed - indexed for MEDLINE]Related articlesFree article

Natural history of a proinsulin-secreting insulinoma: from symptomatic hypoglycemia to clinical diabetes.

Arioglu E, Gottlieb NA, Koch CA, Doppman JL, Grey NJ, Gorden P.

J Clin Endocrinol Metab. 2000 Oct;85(10):3628-30. No abstract available. PMID: 11061513 [PubMed - indexed for MEDLINE]Related articlesFree article

Forty-eight-hour fast: the diagnostic test for insulinoma.

Hirshberg B, Livi A, Bartlett DL, Libutti SK, Alexander HR, Doppman JL, Skarulis MC, Gorden P.

J Clin Endocrinol Metab. 2000 Sep;85(9):3222-6.PMID: 10999812 [PubMed - indexed for MEDLINE]Related articlesFree article

Operative management of islet-cell tumors arising in the head of the pancreas.

Park BJ, Alexander HR, Libutti SK, Huang J, Royalty D, Skarulis MC, Jensen RT, Gorden P, Doppman JL, Shawker TH, Fraker DL, Norton JA, Bartlett DL.

Surgery. 1998 Dec;124(6):1056-61; discussion 1061-2.PMID: 9854583 [PubMed - indexed for MEDLINE]Related articles

Long-term medical treatment of ectopic ACTH syndrome.

Comi RJ, Gorden P.

South Med J. 1998 Nov;91(11):1014-8. Review.PMID: 9824181 [PubMed - indexed for MEDLINE]Related articles