PubMed

Early signaling by vascular endothelial growth factor and placental growth factor in human bone marrow-derived endothelial cells is mediated by superoxide.

Dhar-Mascareno M, Mascareno E, Golde DW.

J Vasc Res. 2009;46(6):601-8. Epub 2009 Jun 30.PMID: 19571580 [PubMed - indexed for MEDLINE]Related articles

Sequential therapy with fludarabine, high-dose cyclophosphamide, and rituximab in previously untreated patients with chronic lymphocytic leukemia produces high-quality responses: molecular remissions predict for durable complete responses.

Lamanna N, Jurcic JG, Noy A, Maslak P, Gencarelli AN, Panageas KS, Heaney ML, Brentjens RJ, Golde DW, Scheinberg DA, Zelenetz AD, Weiss MA.

J Clin Oncol. 2009 Feb 1;27(4):491-7. Epub 2008 Dec 15.PMID: 19075280 [PubMed - indexed for MEDLINE]Related articles

Vitamin C antagonizes the cytotoxic effects of antineoplastic drugs.

Heaney ML, Gardner JR, Karasavvas N, Golde DW, Scheinberg DA, Smith EA, O'Connor OA.

Cancer Res. 2008 Oct 1;68(19):8031-8.PMID: 18829561 [PubMed - indexed for MEDLINE]Related articlesFree article

Caspase-8 dependent TRAIL-induced apoptosis in cancer cell lines is inhibited by vitamin C and catalase.

Perez-Cruz I, Cárcamo JM, Golde DW.

Apoptosis. 2007 Jan;12(1):225-34.PMID: 17031493 [PubMed - indexed for MEDLINE]Related articles

The alpha subunit of the granulocyte-macrophage colony-stimulating factor receptor interacts with c-Kit and inhibits c-Kit signaling.

Chen J, Cárcamo JM, Golde DW.

J Biol Chem. 2006 Aug 4;281(31):22421-6. Epub 2006 Jun 7.PMID: 16760463 [PubMed - indexed for MEDLINE]Related articlesFree article

PI3-kinase activation by GM-CSF in endothelium is upstream of Jak/Stat pathway: role of alphaGMR.

Dhar-Mascareno M, Pedraza A, Golde DW.

Biochem Biophys Res Commun. 2005 Nov 18;337(2):551-6. Epub 2005 Sep 22.PMID: 16202975 [PubMed - indexed for MEDLINE]Related articles

Vitamin C enters mitochondria via facilitative glucose transporter 1 (Glut1) and confers mitochondrial protection against oxidative injury.

KC S, Cárcamo JM, Golde DW.

FASEB J. 2005 Oct;19(12):1657-67.PMID: 16195374 [PubMed - indexed for MEDLINE]Related articlesFree article

A quantitative measurement of the human somatic mutation rate.

Araten DJ, Golde DW, Zhang RH, Thaler HT, Gargiulo L, Notaro R, Luzzatto L.

Cancer Res. 2005 Sep 15;65(18):8111-7. Erratum in: Cancer Res. 2005 Nov 15;65(22):10635. PMID: 16166284 [PubMed - indexed for MEDLINE]Related articlesFree article

Antioxidants prevent oxidative DNA damage and cellular transformation elicited by the over-expression of c-MYC.

K C S, Cárcamo JM, Golde DW.

Mutat Res. 2006 Jan 29;593(1-2):64-79. Epub 2005 Aug 8.PMID: 16085125 [PubMed - indexed for MEDLINE]Related articles

Hypoxia-reoxygenation-induced mitochondrial damage and apoptosis in human endothelial cells are inhibited by vitamin C.

Dhar-Mascareño M, Cárcamo JM, Golde DW.

Free Radic Biol Med. 2005 May 15;38(10):1311-22.PMID: 15855049 [PubMed - indexed for MEDLINE]Related articles

Hydrogen peroxide generated extracellularly by receptor-ligand interaction facilitates cell signaling.

DeYulia GJ Jr, Cárcamo JM, Bórquez-Ojeda O, Shelton CC, Golde DW.

Proc Natl Acad Sci U S A. 2005 Apr 5;102(14):5044-9. Epub 2005 Mar 28.PMID: 15795385 [PubMed - indexed for MEDLINE]Related articlesFree article

Vitamin C protects HL60 and U266 cells from arsenic toxicity.

Karasavvas N, Cárcamo JM, Stratis G, Golde DW.

Blood. 2005 May 15;105(10):4004-12. Epub 2005 Jan 27.PMID: 15677571 [PubMed - indexed for MEDLINE]Related articlesFree article

Vitamin C inhibits hypoxia-induced damage and apoptotic signaling pathways in cardiomyocytes and ischemic hearts.

Guaiquil VH, Golde DW, Beckles DL, Mascareno EJ, Siddiqui MA.

Free Radic Biol Med. 2004 Nov 1;37(9):1419-29.PMID: 15454281 [PubMed - indexed for MEDLINE]Related articles

Vitamin C is a kinase inhibitor: dehydroascorbic acid inhibits IkappaBalpha kinase beta.

Cárcamo JM, Pedraza A, Bórquez-Ojeda O, Zhang B, Sanchez R, Golde DW.

Mol Cell Biol. 2004 Aug;24(15):6645-52.PMID: 15254232 [PubMed - indexed for MEDLINE]Related articlesFree article

A human sodium-dependent vitamin C transporter 2 isoform acts as a dominant-negative inhibitor of ascorbic acid transport.

Lutsenko EA, Carcamo JM, Golde DW.

Mol Cell Biol. 2004 Apr;24(8):3150-6. Erratum in: Mol Cell Biol. 2004 Jul;24(14):6537. PMID: 15060139 [PubMed - indexed for MEDLINE]Related articlesFree article

Vitamin C in cancer.

Golde DW.

Integr Cancer Ther. 2003 Jun;2(2):158-9. Review. No abstract available. PMID: 15035904 [PubMed - indexed for MEDLINE]Related articles

The laminin receptor modulates granulocyte-macrophage colony-stimulating factor receptor complex formation and modulates its signaling.

Chen J, Cárcamo JM, Bórquez-Ojeda O, Erdjument-Bromage H, Tempst P, Golde DW.

Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14000-5. Epub 2003 Nov 12.PMID: 14614142 [PubMed - indexed for MEDLINE]Related articlesFree article

Vitamin C inhibits FAS-induced apoptosis in monocytes and U937 cells.

Perez-Cruz I, Carcamo JM, Golde DW.

Blood. 2003 Jul 1;102(1):336-43. Epub 2003 Mar 6.PMID: 12623840 [PubMed - indexed for MEDLINE]Related articlesFree article

Granulocyte-macrophage colony-stimulating factor signals for increased glucose transport via phosphatidylinositol 3-kinase- and hydrogen peroxide-dependent mechanisms.

Dhar-Mascareno M, Chen J, Zhang RH, Cárcamo JM, Golde DW.

J Biol Chem. 2003 Mar 28;278(13):11107-14. Epub 2003 Jan 21.PMID: 12538575 [PubMed - indexed for MEDLINE]Related articlesFree article

Recycling of vitamin C by a bystander effect.

Nualart FJ, Rivas CI, Montecinos VP, Godoy AS, Guaiquil VH, Golde DW, Vera JC.

J Biol Chem. 2003 Mar 21;278(12):10128-33. Epub 2002 Nov 14.PMID: 12435736 [PubMed - indexed for MEDLINE]Related articlesFree article

Vitamin C suppresses TNF alpha-induced NF kappa B activation by inhibiting I kappa B alpha phosphorylation.

Cárcamo JM, Pedraza A, Bórquez-Ojeda O, Golde DW.

Biochemistry. 2002 Oct 29;41(43):12995-3002.PMID: 12390026 [PubMed - indexed for MEDLINE]Related articles

Cladribine underdosing in hairy-cell leukemia: a cause for apparent response failure.

Golde DW, Jakubowiak A, Caggiano J, Heaney ML.

Leuk Lymphoma. 2002 Feb;43(2):365-7.PMID: 11999571 [PubMed - indexed for MEDLINE]Related articles

Vitamin C inhibits granulocyte macrophage-colony-stimulating factor-induced signaling pathways.

Cárcamo JM, Bórquez-Ojeda O, Golde DW.

Blood. 2002 May 1;99(9):3205-12.PMID: 11964284 [PubMed - indexed for MEDLINE]Related articlesFree article

The precrystalline cytoplasmic granules of alveolar soft part sarcoma contain monocarboxylate transporter 1 and CD147.

Ladanyi M, Antonescu CR, Drobnjak M, Baren A, Lui MY, Golde DW, Cordon-Cardo C.

Am J Pathol. 2002 Apr;160(4):1215-21.PMID: 11943706 [PubMed - indexed for MEDLINE]Related articlesFree article

Vitamin C prevents DNA mutation induced by oxidative stress.

Lutsenko EA, Cárcamo JM, Golde DW.

J Biol Chem. 2002 May 10;277(19):16895-9. Epub 2002 Mar 7. Erratum in: J Biol Chem 2002 Jul 26;277(30):27576. PMID: 11884413 [PubMed - indexed for MEDLINE]Related articlesFree article

Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experimental stroke.

Huang J, Agus DB, Winfree CJ, Kiss S, Mack WJ, McTaggart RA, Choudhri TF, Kim LJ, Mocco J, Pinsky DJ, Fox WD, Israel RJ, Boyd TA, Golde DW, Connolly ES Jr.

Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11720-4.PMID: 11573006 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanism of vitamin C inhibition of cell death induced by oxidative stress in glutathione-depleted HL-60 cells.

Guaiquil VH, Vera JC, Golde DW.

J Biol Chem. 2001 Nov 2;276(44):40955-61. Epub 2001 Aug 30.PMID: 11533037 [PubMed - indexed for MEDLINE]Related articlesFree article

The predicted ATP-binding domains in the hexose transporter GLUT1 critically affect transporter activity.

Liu Q, Vera JC, Peng H, Golde DW.

Biochemistry. 2001 Jul 3;40(26):7874-81.PMID: 11425315 [PubMed - indexed for MEDLINE]Related articles

Direct inhibition of the hexose transporter GLUT1 by tyrosine kinase inhibitors.

Vera JC, Reyes AM, Velásquez FV, Rivas CI, Zhang RH, Strobel P, Slebe JC, Núñez-Alarcón J, Golde DW.

Biochemistry. 2001 Jan 23;40(3):777-90.PMID: 11170395 [PubMed - indexed for MEDLINE]Related articles

Critical evaluation of the World Health Organization classification of myelodysplasia and acute myeloid leukemia.

Heaney ML, Golde DW; WHO.

Curr Oncol Rep. 2000 Mar;2(2):140-3. Review.PMID: 11122835 [PubMed - indexed for MEDLINE]Related articles

Consolidation therapy with high-dose cyclophosphamide improves the quality of response in patients with chronic lymphocytic leukemia treated with fludarabine as induction therapy.

Weiss MA, Glenn M, Maslak P, Rahman Z, Noy A, Zelenetz A, Scheinberg DA, Golde DW.

Leukemia. 2000 Sep;14(9):1577-82.PMID: 10995003 [PubMed - indexed for MEDLINE]Related articles

Molecular characterization of a granulocyte macrophage-colony-stimulating factor receptor alpha subunit-associated protein, GRAP.

Tu J, Karasavvas N, Heaney ML, Vera JC, Golde DW.

Blood. 2000 Aug 1;96(3):794-9.PMID: 10910889 [PubMed - indexed for MEDLINE]Related articlesFree article

High-affinity binding to the GM-CSF receptor requires intact N-glycosylation sites in the extracellular domain of the beta subunit.

Niu L, Heaney ML, Vera JC, Golde DW.

Blood. 2000 Jun 1;95(11):3357-62.PMID: 10828016 [PubMed - indexed for MEDLINE]Related articlesFree article

Kinetic resolution of two mechanisms for high-affinity granulocyte-macrophage colony-stimulating factor binding to its receptor.

Niu L, Golde DW, Vera JC, Heaney ML.

Blood. 1999 Dec 1;94(11):3748-53.PMID: 10572088 [PubMed - indexed for MEDLINE]Related articlesFree article

Prostate cancer cell cycle regulators: response to androgen withdrawal and development of androgen independence.

Agus DB, Cordon-Cardo C, Fox W, Drobnjak M, Koff A, Golde DW, Scher HI.

J Natl Cancer Inst. 1999 Nov 3;91(21):1869-76.PMID: 10547394 [PubMed - indexed for MEDLINE]Related articlesFree article

Response of prostate cancer to anti-Her-2/neu antibody in androgen-dependent and -independent human xenograft models.

Agus DB, Scher HI, Higgins B, Fox WD, Heller G, Fazzari M, Cordon-Cardo C, Golde DW.

Cancer Res. 1999 Oct 1;59(19):4761-4.PMID: 10519379 [PubMed - indexed for MEDLINE]Related articlesFree article

Stromal cell oxidation: a mechanism by which tumors obtain vitamin C.

Agus DB, Vera JC, Golde DW.

Cancer Res. 1999 Sep 15;59(18):4555-8.PMID: 10493506 [PubMed - indexed for MEDLINE]Related articlesFree article

Myelodysplasia.

Heaney ML, Golde DW.

N Engl J Med. 1999 May 27;340(21):1649-60. Review. No abstract available. PMID: 10341278 [PubMed - indexed for MEDLINE]Related articles

Expression of the human GM-CSF receptor alpha subunit in Saccharomyces cerevisiae.

Tu J, Golde DW, Vera JC, Heaney ML.

Cytokines Cell Mol Ther. 1998 Sep;4(3):147-51.PMID: 9825839 [PubMed - indexed for MEDLINE]Related articles

Insulin-like growth factor-I resistance.

Jain S, Golde DW, Bailey R, Geffner ME.

Endocr Rev. 1998 Oct;19(5):625-46. Review. No abstract available. PMID: 9793761 [PubMed - indexed for MEDLINE]Related articlesFree article

Human monocarboxylate transporter 2 (MCT2) is a high affinity pyruvate transporter.

Lin RY, Vera JC, Chaganti RS, Golde DW.

J Biol Chem. 1998 Oct 30;273(44):28959-65.PMID: 9786900 [PubMed - indexed for MEDLINE]Related articlesFree article

Soluble receptors in human disease.

Heaney ML, Golde DW.

J Leukoc Biol. 1998 Aug;64(2):135-46. Review.PMID: 9715251 [PubMed - indexed for MEDLINE]Related articlesFree article

Positron emission tomography of a human prostate cancer xenograft: association of changes in deoxyglucose accumulation with other measures of outcome following androgen withdrawal.

Agus DB, Golde DW, Sgouros G, Ballangrud A, Cordon-Cardo C, Scher HI.

Cancer Res. 1998 Jul 15;58(14):3009-14.PMID: 9679964 [PubMed - indexed for MEDLINE]Related articlesFree article

A phase I trial of a single high dose of idarubicin combined with high-dose cytarabine as induction therapy in relapsed or refractory adult patients with acute lymphoblastic leukemia.

Weiss MA, Drullinsky P, Maslak P, Scheinberg D, Golde DW.

Leukemia. 1998 Jun;12(6):865-8.PMID: 9639412 [PubMed - indexed for MEDLINE]Related articles

Colony-stimulating factors signal for increased transport of vitamin C in human host defense cells.

Vera JC, Rivas CI, Zhang RH, Golde DW.

Blood. 1998 Apr 1;91(7):2536-46.PMID: 9516155 [PubMed - indexed for MEDLINE]Related articlesFree article

Vitamin C crosses the blood-brain barrier in the oxidized form through the glucose transporters.

Agus DB, Gambhir SS, Pardridge WM, Spielholz C, Baselga J, Vera JC, Golde DW.

J Clin Invest. 1997 Dec 1;100(11):2842-8.PMID: 9389750 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of granulocyte-macrophage colony-stimulating factor receptors in human prostate cancer.

Rivas CI, Vera JC, Delgado-López F, Heaney ML, Guaiquil VH, Zhang RH, Scher HI, Concha II, Nualart F, Cordon-Cardo C, Golde DW.

Blood. 1998 Feb 1;91(3):1037-43.PMID: 9446667 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased facilitated transport of dehydroascorbic acid without changes in sodium-dependent ascorbate transport in human melanoma cells.

Spielholz C, Golde DW, Houghton AN, Nualart F, Vera JC.

Cancer Res. 1997 Jun 15;57(12):2529-37.PMID: 9192836 [PubMed - indexed for MEDLINE]Related articlesFree article

Human erythrocytes express GLUT5 and transport fructose.

Concha II, Velásquez FV, Martínez JM, Angulo C, Droppelmann A, Reyes AM, Slebe JC, Vera JC, Golde DW.

Blood. 1997 Jun 1;89(11):4190-5.PMID: 9166863 [PubMed - indexed for MEDLINE]Related articlesFree article

Efficient transport and accumulation of vitamin C in HL-60 cells depleted of glutathione.

Guaiquil VH, Farber CM, Golde DW, Vera JC.

J Biol Chem. 1997 Apr 11;272(15):9915-21.PMID: 9092530 [PubMed - indexed for MEDLINE]Related articlesFree article