PubMed

Reducing effect of a Phaseolus vulgaris dry extract on food intake, body weight, and glycemia in rats.

Fantini N, Cabras C, Lobina C, Colombo G, Gessa GL, Riva A, Donzelli F, Morazzoni P, Bombardelli E, Carai MA.

J Agric Food Chem. 2009 Oct 14;57(19):9316-23.PMID: 19731962 [PubMed - in process]Related articles

Delineating the psychic structure of substance abuse and addictions: Should anxiety, mood and impulse-control dysregulation be included?

Pani PP, Maremmani I, Trogu E, Gessa GL, Ruiz P, Akiskal HS.

J Affect Disord. 2009 Jul 6. [Epub ahead of print]PMID: 19584019 [PubMed - as supplied by publisher]Related articles

Reduction of alcohol's reinforcing and motivational properties by the positive allosteric modulator of the GABA(B) receptor, BHF177, in alcohol-preferring rats.

Maccioni P, Carai MA, Kaupmann K, Guery S, Froestl W, Leite-Morris KA, Gessa GL, Colombo G.

Alcohol Clin Exp Res. 2009 Oct;33(10):1749-56. Epub 2009 Jul 1.PMID: 19572981 [PubMed - in process]Related articles

Specific reduction of alcohol's motivational properties by the positive allosteric modulator of the GABAB receptor, GS39783--comparison with the effect of the GABAB receptor direct agonist, baclofen.

Maccioni P, Fantini N, Froestl W, Carai MA, Gessa GL, Colombo G.

Alcohol Clin Exp Res. 2008 Sep;32(9):1558-64. Epub 2008 Jul 9.PMID: 18616673 [PubMed - indexed for MEDLINE]Related articles

Sleep deprivation disrupts prepulse inhibition of the startle reflex: reversal by antipsychotic drugs.

Frau R, Orrù M, Puligheddu M, Gessa GL, Mereu G, Marrosu F, Bortolato M.

Int J Neuropsychopharmacol. 2008 Nov;11(7):947-55. Epub 2008 May 14.PMID: 18477413 [PubMed - indexed for MEDLINE]Related articles

Suppression by the cannabinoid CB1 receptor antagonist, rimonabant, of the reinforcing and motivational properties of a chocolate-flavoured beverage in rats.

Maccioni P, Pes D, Carai MA, Gessa GL, Colombo G.

Behav Pharmacol. 2008 May;19(3):197-209.PMID: 18469537 [PubMed - indexed for MEDLINE]Related articles

Baclofen attenuates cue-induced reinstatement of alcohol-seeking behavior in Sardinian alcohol-preferring (sP) rats.

Maccioni P, Bienkowski P, Carai MA, Gessa GL, Colombo G.

Drug Alcohol Depend. 2008 Jun 1;95(3):284-7. Epub 2008 Mar 28.PMID: 18374518 [PubMed - indexed for MEDLINE]Related articles

gamma-Hydroxybutyric acid (GHB) suppresses alcohol's motivational properties in alcohol-preferring rats.

Maccioni P, Pes D, Fantini N, Carai MA, Gessa GL, Colombo G.

Alcohol. 2008 Mar;42(2):107-13.PMID: 18358989 [PubMed - indexed for MEDLINE]Related articles

Antipsychotic-like properties of 5-alpha-reductase inhibitors.

Bortolato M, Frau R, Orrù M, Bourov Y, Marrosu F, Mereu G, Devoto P, Gessa GL.

Neuropsychopharmacology. 2008 Dec;33(13):3146-56. Epub 2008 Mar 19.PMID: 18354385 [PubMed - indexed for MEDLINE]Related articlesFree article

Gamma-aminobutyric acidB (GABAB)-receptor mediation of different in vivo effects of gamma-butyrolactone.

Carai MA, Lobina C, Maccioni P, Cabras C, Colombo G, Gessa GL.

J Pharmacol Sci. 2008 Feb;106(2):199-207. Epub 2008 Feb 9.PMID: 18270475 [PubMed - indexed for MEDLINE]Related articlesFree article

6-Hydroxydopamine lesion in the ventral tegmental area fails to reduce extracellular dopamine in the cerebral cortex.

Devoto P, Flore G, Saba P, Castelli MP, Piras AP, Luesu W, Viaggi MC, Ennas MG, Gessa GL.

J Neurosci Res. 2008 May 15;86(7):1647-58.PMID: 18189323 [PubMed - indexed for MEDLINE]Related articles

The cannabinoid CB1 receptor antagonist, rimonabant, as a promising pharmacotherapy for alcohol dependence: preclinical evidence.

Colombo G, Orrù A, Lai P, Cabras C, Maccioni P, Rubio M, Gessa GL, Carai MA.

Mol Neurobiol. 2007 Aug;36(1):102-12. Epub 2007 Jul 3. Review.PMID: 17952655 [PubMed - indexed for MEDLINE]Related articles

Repeated exposure to alcoholic beer does not induce long-lasting changes in alcohol self-administration and intake in Sardinian alcohol-preferring and Sardinian non-preferring rats.

Orrù A, Lobina C, Maccioni P, Gessa GL, Carai MA, Colombo G.

Alcohol Alcohol. 2007 Nov-Dec;42(6):513-24. Epub 2007 Sep 18.PMID: 17878214 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term lithium treatment and survival from external causes including suicide.

Bocchetta A, Fadda D, Satta G, Del Zompo M, Gessa GL, Cocco P.

J Clin Psychopharmacol. 2007 Oct;27(5):544-6. No abstract available. PMID: 17873708 [PubMed - indexed for MEDLINE]Related articles

Alcohol use disorders, and at-risk drinking in patients affected by a mood disorder, in Cagliari, Italy: sensitivity and specificity of different questionnaires.

Agabio R, Marras P, Gessa GL, Carpiniello B.

Alcohol Alcohol. 2007 Nov-Dec;42(6):575-81. Epub 2007 Aug 31.PMID: 17766313 [PubMed - indexed for MEDLINE]Related articlesFree article

Dysregulation of the endogenous cannabinoid system in adult rats prenatally treated with the cannabinoid agonist WIN 55,212-2.

Castelli MP, Paola Piras A, D'Agostino A, Pibiri F, Perra S, Gessa GL, Maccarrone M, Pistis M.

Eur J Pharmacol. 2007 Nov 14;573(1-3):11-9. Epub 2007 Jul 4.PMID: 17644084 [PubMed - indexed for MEDLINE]Related articles

Gamma-hydroxybutyrate reduces both withdrawal syndrome and hypercortisolism in severe abstinent alcoholics: an open study vs. diazepam.

Nava F, Premi S, Manzato E, Campagnola W, Lucchini A, Gessa GL.

Am J Drug Alcohol Abuse. 2007;33(3):379-92.PMID: 17613965 [PubMed - indexed for MEDLINE]Related articles

Activation of GABA(B) receptors reverses spontaneous gating deficits in juvenile DBA/2J mice.

Bortolato M, Frau R, Orrù M, Piras AP, Fà M, Tuveri A, Puligheddu M, Gessa GL, Castelli MP, Mereu G, Marrosu F.

Psychopharmacology (Berl). 2007 Oct;194(3):361-9. Epub 2007 Jun 29.PMID: 17604981 [PubMed - indexed for MEDLINE]Related articles

Baclofen suppresses alcohol intake and craving for alcohol in a schizophrenic alcohol-dependent patient: a case report.

Agabio R, Marras P, Addolorato G, Carpiniello B, Gessa GL.

J Clin Psychopharmacol. 2007 Jun;27(3):319-20. No abstract available. PMID: 17502794 [PubMed - indexed for MEDLINE]Related articles

Cue-induced reinstatement of ethanol seeking in Sardinian alcohol-preferring rats.

Maccioni P, Orrú A, Korkosz A, Gessa GL, Carai MA, Colombo G, Bienkowski P.

Alcohol. 2007 Feb;41(1):31-9.PMID: 17452297 [PubMed - indexed for MEDLINE]Related articles

Reducing effect of the positive allosteric modulator of the GABA(B) receptor, GS39,783, on alcohol self-administration in alcohol-preferring rats.

Maccioni P, Pes D, Orrù A, Froestl W, Gessa GL, Carai MA, Colombo G.

Psychopharmacology (Berl). 2007 Aug;193(2):171-8. Epub 2007 Mar 29.PMID: 17393141 [PubMed - indexed for MEDLINE]Related articles

Medial forebrain bundle stimulation evokes endocannabinoid-mediated modulation of ventral tegmental area dopamine neuron firing in vivo.

Pillolla G, Melis M, Perra S, Muntoni AL, Gessa GL, Pistis M.

Psychopharmacology (Berl). 2007 Apr;191(3):843-53. Epub 2007 Feb 16.PMID: 17334799 [PubMed - indexed for MEDLINE]Related articles

Evaluation for the withdrawal syndrome from gamma-hydroxybutyric acid (GHB), gamma-butyrolactone (GBL), and 1,4-butanediol (1,4-BD) in different rat lines.

Quang LS, Colombo G, Lobina C, Maccioni P, Orru A, Gessa GL, Maher TJ, Carai MA.

Ann N Y Acad Sci. 2006 Aug;1074:545-58.PMID: 17105952 [PubMed - indexed for MEDLINE]Related articles

Baclofen-induced suppression of alcohol deprivation effect in Sardinian alcohol-preferring (sP) rats exposed to different alcohol concentrations.

Colombo G, Serra S, Vacca G, Carai MA, Gessa GL.

Eur J Pharmacol. 2006 Nov 21;550(1-3):123-6. Epub 2006 Sep 8.PMID: 17022968 [PubMed - indexed for MEDLINE]Related articles

Phenotypic characterization of genetically selected Sardinian alcohol-preferring (sP) and -non-preferring (sNP) rats.

Colombo G, Lobina C, Carai MA, Gessa GL.

Addict Biol. 2006 Sep;11(3-4):324-38. Review.PMID: 16961762 [PubMed - indexed for MEDLINE]Related articles

Efficacy of rimonabant and other cannabinoid CB1 receptor antagonists in reducing food intake and body weight: preclinical and clinical data.

Carai MA, Colombo G, Maccioni P, Gessa GL.

CNS Drug Rev. 2006 Summer;12(2):91-9. Review.PMID: 16958983 [PubMed - indexed for MEDLINE]Related articles

Investigation on the relationship between cannabinoid CB1 and opioid receptors in gastrointestinal motility in mice.

Carai MA, Colombo G, Gessa GL, Yalamanchili R, Basavarajappa BS, Hungund BL.

Br J Pharmacol. 2006 Aug;148(8):1043-50. Epub 2006 Jul 17. Erratum in: Br J Pharmacol. 2007 Jan;150(2):249. Basavarajppa, Balapal S [corrected to Basavarajappa, Balapal S]. PMID: 16847440 [PubMed - indexed for MEDLINE]Related articlesFree article

Protective activation of the endocannabinoid system during ischemia in dopamine neurons.

Melis M, Pillolla G, Bisogno T, Minassi A, Petrosino S, Perra S, Muntoni AL, Lutz B, Gessa GL, Marsicano G, Di Marzo V, Pistis M.

Neurobiol Dis. 2006 Oct;24(1):15-27. Epub 2006 Jun 8.PMID: 16762556 [PubMed - indexed for MEDLINE]Related articles

Cannabinoids modulate spontaneous neuronal activity and evoked inhibition of locus coeruleus noradrenergic neurons.

Muntoni AL, Pillolla G, Melis M, Perra S, Gessa GL, Pistis M.

Eur J Neurosci. 2006 May;23(9):2385-94.PMID: 16706846 [PubMed - indexed for MEDLINE]Related articles

Identification of miltirone as active ingredient of Salvia miltiorrhiza responsible for the reducing effect of root extracts on alcohol intake in rats.

Colombo G, Serra S, Vacca G, Orrù A, Maccioni P, Morazzoni P, Bombardelli E, Riva A, Gessa GL, Carai MA.

Alcohol Clin Exp Res. 2006 May;30(5):754-62.PMID: 16634843 [PubMed - indexed for MEDLINE]Related articles

Anxiolytic-like properties of the anandamide transport inhibitor AM404.

Bortolato M, Campolongo P, Mangieri RA, Scattoni ML, Frau R, Trezza V, La Rana G, Russo R, Calignano A, Gessa GL, Cuomo V, Piomelli D.

Neuropsychopharmacology. 2006 Dec;31(12):2652-9. Epub 2006 Mar 15.PMID: 16541083 [PubMed - indexed for MEDLINE]Related articlesFree article

Lack of tolerance to the suppressing effect of rimonabant on chocolate intake in rats.

Gessa GL, Orrù A, Lai P, Maccioni P, Lecca R, Lobina C, Carai MA, Colombo G.

Psychopharmacology (Berl). 2006 Apr;185(2):248-54. Epub 2006 Feb 21.PMID: 16491428 [PubMed - indexed for MEDLINE]Related articles

Alcohol use disorders in primary care patients in Cagliari, Italy.

Agabio R, Nioi M, Serra C, Valle P, Gessa GL.

Alcohol Alcohol. 2006 May-Jun;41(3):341-4. Epub 2006 Feb 20.PMID: 16490789 [PubMed - indexed for MEDLINE]Related articlesFree article

Baclofen in the treatment of alcohol withdrawal syndrome: a comparative study vs diazepam.

Addolorato G, Leggio L, Abenavoli L, Agabio R, Caputo F, Capristo E, Colombo G, Gessa GL, Gasbarrini G.

Am J Med. 2006 Mar;119(3):276.e13-8.PMID: 16490478 [PubMed - indexed for MEDLINE]Related articles

Resuscitative treatments on 1,4-butanediol mortality in mice.

Carai MA, Colombo G, Quang LS, Maher TJ, Gessa GL.

Ann Emerg Med. 2006 Feb;47(2):184-9. Epub 2005 Dec 27.PMID: 16431232 [PubMed - indexed for MEDLINE]Related articles

Prenatal exposure to a cannabinoid receptor agonist does not affect sensorimotor gating in rats.

Bortolato M, Frau R, Orrù M, Casti A, Aru GN, Fà M, Manunta M, Usai A, Mereu G, Gessa GL.

Eur J Pharmacol. 2006 Feb 15;531(1-3):166-70. Epub 2006 Jan 19.PMID: 16423346 [PubMed - indexed for MEDLINE]Related articles

Baclofen-induced reduction of alcohol reinforcement in alcohol-preferring rats.

Maccioni P, Serra S, Vacca G, Orrù A, Pes D, Agabio R, Addolorato G, Carai MA, Gessa GL, Colombo G.

Alcohol. 2005 Jul;36(3):161-8.PMID: 16377457 [PubMed - indexed for MEDLINE]Related articles

Reducing effect of the positive allosteric modulators of the GABA(B) receptor, CGP7930 and GS39783, on alcohol intake in alcohol-preferring rats.

Orrù A, Lai P, Lobina C, Maccioni P, Piras P, Scanu L, Froestl W, Gessa GL, Carai MA, Colombo G.

Eur J Pharmacol. 2005 Nov 21;525(1-3):105-11. Epub 2005 Nov 14.PMID: 16289452 [PubMed - indexed for MEDLINE]Related articles

Involvement of the endogenous cannabinoid system in the effects of alcohol in the mesolimbic reward circuit: electrophysiological evidence in vivo.

Perra S, Pillolla G, Melis M, Muntoni AL, Gessa GL, Pistis M.

Psychopharmacology (Berl). 2005 Dec;183(3):368-77. Epub 2005 Oct 15.PMID: 16228194 [PubMed - indexed for MEDLINE]Related articles

Differential G-protein coupling to GABAB receptor in limbic areas of alcohol-preferring and -nonpreferring rats.

Castelli MP, Pibiri F, Piras AP, Carboni G, Orrù A, Gessa GL, Carai MA, Colombo G.

Eur J Pharmacol. 2005 Oct 31;523(1-3):67-70. Epub 2005 Oct 13.PMID: 16226245 [PubMed - indexed for MEDLINE]Related articles

Endogenous gamma-aminobutyric acid (GABA)(A) receptor active neurosteroids and the sedative/hypnotic action of gamma-hydroxybutyric acid (GHB): a study in GHB-S (sensitive) and GHB-R (resistant) rat lines.

Barbaccia ML, Carai MA, Colombo G, Lobina C, Purdy RH, Gessa GL.

Neuropharmacology. 2005 Jul;49(1):48-58. Epub 2005 Mar 31.PMID: 15992580 [PubMed - indexed for MEDLINE]Related articles

Kappa opioid receptor activation disrupts prepulse inhibition of the acoustic startle in rats.

Bortolato M, Aru GN, Frau R, Orrù M, Fà M, Manunta M, Puddu M, Mereu G, Gessa GL.

Biol Psychiatry. 2005 Jun 15;57(12):1550-8.PMID: 15953492 [PubMed - indexed for MEDLINE]Related articles

Resuscitative effect of a gamma-aminobutyric acid B receptor antagonist on gamma-hydroxybutyric acid mortality in mice.

Carai MA, Colombo G, Gessa GL.

Ann Emerg Med. 2005 Jun;45(6):614-9.PMID: 15940094 [PubMed - indexed for MEDLINE]Related articles

Endocannabinoid system and alcohol addiction: pharmacological studies.

Colombo G, Serra S, Vacca G, Carai MA, Gessa GL.

Pharmacol Biochem Behav. 2005 Jun;81(2):369-80. Review.PMID: 15939463 [PubMed - indexed for MEDLINE]Related articles

Rimonabant: the first therapeutically relevant cannabinoid antagonist.

Carai MA, Colombo G, Gessa GL.

Life Sci. 2005 Sep 23;77(19):2339-50. Review.PMID: 15935395 [PubMed - indexed for MEDLINE]Related articles

Suppression of maintenance of alcohol-drinking behavior by the concurrent availability of saccharin in Sardinian alcohol-preferring (sP) rats.

Colombo G, Lobina C, Maccioni P, Mascia MF, Orrù A, Gessa GL, Carai MA.

Alcohol. 2005 Jan;35(1):35-41.PMID: 15922136 [PubMed - indexed for MEDLINE]Related articles

Suppression of acquisition of alcohol-drinking behavior by the concurrent availability of saccharin in Sardinian alcohol-preferring (sP) rats.

Colombo G, Lobina C, Maccioni P, Mascia MF, Orrù A, Gessa GL, Carai MA.

Alcohol. 2005 Jan;35(1):27-33.PMID: 15922135 [PubMed - indexed for MEDLINE]Related articles

Up-regulation of GABA(B) receptors by chronic administration of the GABA(B) receptor antagonist SCH 50,911.

Pibiri F, Carboni G, Carai MA, Gessa GL, Castelli MP.

Eur J Pharmacol. 2005 May 16;515(1-3):94-8.PMID: 15893746 [PubMed - indexed for MEDLINE]Related articles

Withdrawal syndrome from gamma-hydroxybutyric acid (GHB) and 1,4-butanediol (1,4-BD) in Sardinian alcohol-preferring rats.

Carai MA, Quang LS, Atzeri S, Lobina C, Maccioni P, Orrù A, Gessa GL, Maher TJ, Colombo G.

Brain Res Brain Res Protoc. 2005 Jul;15(2):75-8.PMID: 15886053 [PubMed - indexed for MEDLINE]Related articles

GHB-C rats: the control line of GHB-sensitive (GHB-S) and GHB-resistant (GHB-R) rats.

Lobina C, Colombo G, Orrù A, Maccioni P, Gessa GL, Carai MA.

Brain Res Brain Res Protoc. 2005 May;15(1):1-5.PMID: 15878144 [PubMed - indexed for MEDLINE]Related articles