PubMed

Primary vulvar Ewing sarcoma/primitive neuroectodermal tumor: a report of 2 cases and review of the literature.

Cetiner H, Kir G, Gelmann EP, Ozdemirli M.

Int J Gynecol Cancer. 2009 Aug;19(6):1131-6.PMID: 19820381 [PubMed - in process]Related articles

Interactions of the acidic domain and SRF interacting motifs with the NKX3.1 homeodomain.

Ju JH, Maeng JS, Lee DY, Piszczek G, Gelmann EP, Gruschus JM.

Biochemistry. 2009 Nov 10;48(44):10601-7.PMID: 19780584 [PubMed - indexed for MEDLINE]Related articles

Cumulative incidence of false-positive results in repeated, multimodal cancer screening.

Croswell JM, Kramer BS, Kreimer AR, Prorok PC, Xu JL, Baker SG, Fagerstrom R, Riley TL, Clapp JD, Berg CD, Gohagan JK, Andriole GL, Chia D, Church TR, Crawford ED, Fouad MN, Gelmann EP, Lamerato L, Reding DJ, Schoen RE.

Ann Fam Med. 2009 May-Jun;7(3):212-22.PMID: 19433838 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinically relevant prognostic markers for prostate cancer: the search goes on.

Gelmann EP, Henshall SM.

Ann Intern Med. 2009 May 5;150(9):647-9. No abstract available. PMID: 19414846 [PubMed - indexed for MEDLINE]Related articlesFree article

Mortality results from a randomized prostate-cancer screening trial.

Andriole GL, Crawford ED, Grubb RL 3rd, Buys SS, Chia D, Church TR, Fouad MN, Gelmann EP, Kvale PA, Reding DJ, Weissfeld JL, Yokochi LA, O'Brien B, Clapp JD, Rathmell JM, Riley TL, Hayes RB, Kramer BS, Izmirlian G, Miller AB, Pinsky PF, Prorok PC, Gohagan JK, Berg CD; PLCO Project Team.

N Engl J Med. 2009 Mar 26;360(13):1310-9. Epub 2009 Mar 18. Erratum in: N Engl J Med. 2009 Apr 23;360(17):1797. PMID: 19297565 [PubMed - indexed for MEDLINE]Related articlesFree article

NKX3.1 activates expression of insulin-like growth factor binding protein-3 to mediate insulin-like growth factor-I signaling and cell proliferation.

Muhlbradt E, Asatiani E, Ortner E, Wang A, Gelmann EP.

Cancer Res. 2009 Mar 15;69(6):2615-22. Epub 2009 Mar 3.PMID: 19258508 [PubMed - indexed for MEDLINE]Related articles

Prostate cancer screening in the Prostate, Lung, Colorectal and Ovarian cancer screening trial: update on findings from the initial four rounds of screening in a randomized trial.

Grubb RL 3rd, Pinsky PF, Greenlee RT, Izmirlian G, Miller AB, Hickey TP, Riley TL, Mabie JE, Levin DL, Chia D, Kramer BS, Reding DJ, Church TR, Yokochi LA, Kvale PA, Weissfeld JL, Urban DA, Buys SS, Gelmann EP, Ragard LR, Crawford ED, Prorok PC, Gohagan JK, Berg CD, Andriole GL.

BJU Int. 2008 Dec;102(11):1524-30.PMID: 19035857 [PubMed - indexed for MEDLINE]Related articles

Inflammatory cytokines induce phosphorylation and ubiquitination of prostate suppressor protein NKX3.1.

Markowski MC, Bowen C, Gelmann EP.

Cancer Res. 2008 Sep 1;68(17):6896-901.PMID: 18757402 [PubMed - indexed for MEDLINE]Related articlesFree article

Silencing mediator for retinoid and thyroid hormone receptor and nuclear receptor corepressor attenuate transcriptional activation by the beta-catenin-TCF4 complex.

Song LN, Gelmann EP.

J Biol Chem. 2008 Sep 19;283(38):25988-99. Epub 2008 Jul 16.PMID: 18632669 [PubMed - indexed for MEDLINE]Related articlesFree article

A phase II study of mifepristone (RU-486) in castration-resistant prostate cancer, with a correlative assessment of androgen-related hormones.

Taplin ME, Manola J, Oh WK, Kantoff PW, Bubley GJ, Smith M, Barb D, Mantzoros C, Gelmann EP, Balk SP.

BJU Int. 2008 May;101(9):1084-9.PMID: 18399827 [PubMed - indexed for MEDLINE]Related articles

Complexities of prostate-cancer risk.

Gelmann EP.

N Engl J Med. 2008 Feb 28;358(9):961-3. Epub 2008 Jan 16. No abstract available. PMID: 18199856 [PubMed - indexed for MEDLINE]Related articles

Transcription factor Stat5 synergizes with androgen receptor in prostate cancer cells.

Tan SH, Dagvadorj A, Shen F, Gu L, Liao Z, Abdulghani J, Zhang Y, Gelmann EP, Zellweger T, Culig Z, Visakorpi T, Bubendorf L, Kirken RA, Karras J, Nevalainen MT.

Cancer Res. 2008 Jan 1;68(1):236-48.PMID: 18172316 [PubMed - indexed for MEDLINE]Related articlesFree article

Serum lycopene, other carotenoids, and prostate cancer risk: a nested case-control study in the prostate, lung, colorectal, and ovarian cancer screening trial.

Peters U, Leitzmann MF, Chatterjee N, Wang Y, Albanes D, Gelmann EP, Friesen MD, Riboli E, Hayes RB.

Cancer Epidemiol Biomarkers Prev. 2007 May;16(5):962-8.PMID: 17507623 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide association study of prostate cancer identifies a second risk locus at 8q24.

Yeager M, Orr N, Hayes RB, Jacobs KB, Kraft P, Wacholder S, Minichiello MJ, Fearnhead P, Yu K, Chatterjee N, Wang Z, Welch R, Staats BJ, Calle EE, Feigelson HS, Thun MJ, Rodriguez C, Albanes D, Virtamo J, Weinstein S, Schumacher FR, Giovannucci E, Willett WC, Cancel-Tassin G, Cussenot O, Valeri A, Andriole GL, Gelmann EP, Tucker M, Gerhard DS, Fraumeni JF Jr, Hoover R, Hunter DJ, Chanock SJ, Thomas G.

Nat Genet. 2007 May;39(5):645-9. Epub 2007 Apr 1.PMID: 17401363 [PubMed - indexed for MEDLINE]Related articles

NKX3.1 homeodomain protein binds to topoisomerase I and enhances its activity.

Bowen C, Stuart A, Ju JH, Tuan J, Blonder J, Conrads TP, Veenstra TD, Gelmann EP.

Cancer Res. 2007 Jan 15;67(2):455-64.PMID: 17234752 [PubMed - indexed for MEDLINE]Related articlesFree article

Repeat prostate biopsy in the prostate, lung, colorectal and ovarian cancer screening trial.

Pinsky PF, Crawford ED, Kramer BS, Andriole GL, Gelmann EP, Grubb R, Greenlee R, Gohagan JK.

BJU Int. 2007 Apr;99(4):775-9. Epub 2007 Jan 12.PMID: 17223921 [PubMed - indexed for MEDLINE]Related articles

Physical and functional interactions between the prostate suppressor homeoprotein NKX3.1 and serum response factor.

Ju JH, Maeng JS, Zemedkun M, Ahronovitz N, Mack JW, Ferretti JA, Gelmann EP, Gruschus JM.

J Mol Biol. 2006 Jul 28;360(5):989-99. Epub 2006 Jun 15.PMID: 16814806 [PubMed - indexed for MEDLINE]Related articles

Molecular biology of prostate-cancer pathogenesis.

Shand RL, Gelmann EP.

Curr Opin Urol. 2006 May;16(3):123-31. Review.PMID: 16679847 [PubMed - indexed for MEDLINE]Related articles

Prostate specific antigen changes as related to the initial prostate specific antigen: data from the prostate, lung, colorectal and ovarian cancer screening trial.

Crawford ED, Pinsky PF, Chia D, Kramer BS, Fagerstrom RM, Andriole G, Reding D, Gelmann EP, Levin DL, Gohagan JK.

J Urol. 2006 Apr;175(4):1286-90; discussion 1290.PMID: 16515981 [PubMed - indexed for MEDLINE]Related articles

Effect of homeodomain protein NKX3.1 R52C polymorphism on prostate gland size.

Rodriguez Ortner E, Hayes RB, Weissfeld J, Gelmann EP.

Urology. 2006 Feb;67(2):311-5. Epub 2006 Jan 25.PMID: 16442598 [PubMed - indexed for MEDLINE]Related articles

Germ-line mutation of NKX3.1 cosegregates with hereditary prostate cancer and alters the homeodomain structure and function.

Zheng SL, Ju JH, Chang BL, Ortner E, Sun J, Isaacs SD, Sun J, Wiley KE, Liu W, Zemedkun M, Walsh PC, Ferretti J, Gruschus J, Isaacs WB, Gelmann EP, Xu J.

Cancer Res. 2006 Jan 1;66(1):69-77.PMID: 16397218 [PubMed - indexed for MEDLINE]Related articlesFree article

Interaction of beta-catenin and TIF2/GRIP1 in transcriptional activation by the androgen receptor.

Song LN, Gelmann EP.

J Biol Chem. 2005 Nov 11;280(45):37853-67. Epub 2005 Sep 1.PMID: 16141201 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of signal transducer and activator of transcription-5 in prostate cancer predicts early recurrence.

Li H, Zhang Y, Glass A, Zellweger T, Gehan E, Bubendorf L, Gelmann EP, Nevalainen MT.

Clin Cancer Res. 2005 Aug 15;11(16):5863-8.PMID: 16115927 [PubMed - indexed for MEDLINE]Related articlesFree article

Methods for etiologic and early marker investigations in the PLCO trial.

Hayes RB, Sigurdson A, Moore L, Peters U, Huang WY, Pinsky P, Reding D, Gelmann EP, Rothman N, Pfeiffer RM, Hoover RN, Berg CD; for the PLCO Trial Team.

Mutat Res. 2005 Dec 30;592(1-2):147-54. Epub 2005 Jul 27.PMID: 16054167 [PubMed - indexed for MEDLINE]Related articles

The ubiquitin-proteasome pathway and its role in cancer.

Mani A, Gelmann EP.

J Clin Oncol. 2005 Jul 20;23(21):4776-89. Review.PMID: 16034054 [PubMed - indexed for MEDLINE]Related articles

Targeted therapies for prostate cancer.

Asatiani E, Gelmann EP.

Expert Opin Ther Targets. 2005 Apr;9(2):283-98. Review.PMID: 15934916 [PubMed - indexed for MEDLINE]Related articles

Prostate Cancer Screening in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial: findings from the initial screening round of a randomized trial.

Andriole GL, Levin DL, Crawford ED, Gelmann EP, Pinsky PF, Chia D, Kramer BS, Reding D, Church TR, Grubb RL, Izmirlian G, Ragard LR, Clapp JD, Prorok PC, Gohagan JK; PLCO Project Team.

J Natl Cancer Inst. 2005 Mar 16;97(6):433-8.PMID: 15770007 [PubMed - indexed for MEDLINE]Related articlesFree article

Deletion, methylation, and expression of the NKX3.1 suppressor gene in primary human prostate cancer.

Asatiani E, Huang WX, Wang A, Rodriguez Ortner E, Cavalli LR, Haddad BR, Gelmann EP.

Cancer Res. 2005 Feb 15;65(4):1164-73.PMID: 15734999 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of genes and proteins specific for prostate cancer.

Gelmann EP, Semmes OJ.

J Urol. 2004 Nov;172(5 Pt 2):S23-6; discussion S26-7. Review.PMID: 15535438 [PubMed - indexed for MEDLINE]Related articles

Fourth International Conference on Innovations and Challenges in Prostate Cancer: Prevention, Detection and Treatment.

Carroll PR, Chan JM, D'Amico AV, Gelmann EP, Iversen P, Klotz L, Nelson JB, Nelson PS, Nelson WG, Oh WK, Rosen N, Rubin MA, Sandler H, Sellers WR, Smith MR, Xu J, McMann MC, Kantoff PW.

J Urol. 2004 Nov;172(5 Pt 2):S3-5. Review. No abstract available. PMID: 15535434 [PubMed - indexed for MEDLINE]Related articles

9-Nitrocamptothecin as second line chemotherapy for men with progressive, metastatic, hormone refractory prostate cancer: Results of the CALGB 99901.

Amin A, Halabi S, Gelmann EP, Stadler W, Vogelzang N, Small E.

Urol Oncol. 2004 Sep-Oct;22(5):398-403.PMID: 15464920 [PubMed - indexed for MEDLINE]Related articles

Long-term outcomes after radical prostatectomy performed in a community-based health maintenance organization.

Zhang Y, Glass A, Bennett N, Oyama KA, Gehan E, Gelmann EP.

Cancer. 2004 Jan 15;100(2):300-7.PMID: 14716764 [PubMed - indexed for MEDLINE]Related articlesFree article

Antiandrogen effects of mifepristone on coactivator and corepressor interactions with the androgen receptor.

Song LN, Coghlan M, Gelmann EP.

Mol Endocrinol. 2004 Jan;18(1):70-85. Epub 2003 Oct 30.PMID: 14593076 [PubMed - indexed for MEDLINE]Related articlesFree article

Searching for the gatekeeper oncogene of prostate cancer.

Gelmann EP.

Crit Rev Oncol Hematol. 2003 Jun 27;46 Suppl:S11-20. Review.PMID: 12850523 [PubMed - indexed for MEDLINE]Related articles

Role of ceramide in mediating apoptosis of irradiated LNCaP prostate cancer cells.

Kimura K, Markowski M, Edsall LC, Spiegel S, Gelmann EP.

Cell Death Differ. 2003 Feb;10(2):240-8.PMID: 12700652 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of NKX3.1 in normal and malignant tissues.

Gelmann EP, Bowen C, Bubendorf L.

Prostate. 2003 May 1;55(2):111-7.PMID: 12661036 [PubMed - indexed for MEDLINE]Related articles

Tissue microarray analysis reveals prognostic significance of syndecan-1 expression in prostate cancer.

Zellweger T, Ninck C, Mirlacher M, Annefeld M, Glass AG, Gasser TC, Mihatsch MJ, Gelmann EP, Bubendorf L.

Prostate. 2003 Apr 1;55(1):20-9.PMID: 12640657 [PubMed - indexed for MEDLINE]Related articles

Beta-catenin binds to the activation function 2 region of the androgen receptor and modulates the effects of the N-terminal domain and TIF2 on ligand-dependent transcription.

Song LN, Herrell R, Byers S, Shah S, Wilson EM, Gelmann EP.

Mol Cell Biol. 2003 Mar;23(5):1674-87.PMID: 12588987 [PubMed - indexed for MEDLINE]Related articlesFree article

Retinoblastoma protein-mediated apoptosis after gamma-irradiation.

Bowen C, Birrer M, Gelmann EP.

J Biol Chem. 2002 Nov 22;277(47):44969-79. Epub 2002 Sep 23.PMID: 12297496 [PubMed - indexed for MEDLINE]Related articlesFree article

Propapoptotic effects of NF-kappaB in LNCaP prostate cancer cells lead to serine protease activation.

Kimura K, Gelmann EP.

Cell Death Differ. 2002 Sep;9(9):972-80.PMID: 12181748 [PubMed - indexed for MEDLINE]Related articlesFree article

The impact of item order on ratings of cancer risk perception.

Taylor KL, Shelby RA, Schwartz MD, Ackerman J, LaSalle VH, Gelmann EP, McGuire C.

Cancer Epidemiol Biomarkers Prev. 2002 Jul;11(7):654-9.PMID: 12101113 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular biology of the androgen receptor.

Gelmann EP.

J Clin Oncol. 2002 Jul 1;20(13):3001-15. Review.PMID: 12089231 [PubMed - indexed for MEDLINE]Related articles

P53 gene mutations: case study of a clinical marker for solid tumors.

Liu MC, Gelmann EP.

Semin Oncol. 2002 Jun;29(3):246-57. Review.PMID: 12063677 [PubMed - indexed for MEDLINE]Related articles

Occurrence of NKX3.1 C154T polymorphism in men with and without prostate cancer and studies of its effect on protein function.

Gelmann EP, Steadman DJ, Ma J, Ahronovitz N, Voeller HJ, Swope S, Abbaszadegan M, Brown KM, Strand K, Hayes RB, Stampfer MJ.

Cancer Res. 2002 May 1;62(9):2654-9.PMID: 11980664 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of cadmium in the regulation of AR gene expression and activity.

Martin MB, Voeller HJ, Gelmann EP, Lu J, Stoica EG, Hebert EJ, Reiter R, Singh B, Danielsen M, Pentecost E, Stoica A.

Endocrinology. 2002 Jan;143(1):263-75.PMID: 11751618 [PubMed - indexed for MEDLINE]Related articlesFree article

Relationship of demographic and clinical factors to free and total prostate-specific antigen.

Gelmann EP, Chia D, Pinsky PF, Andriole GL, Crawford ED, Reding D, Hayes RB, Kramer BS, Woodrum DL, Gohagan JK, Levin DL; PLCO Screening Trial Investigators.

Urology. 2001 Oct;58(4):561-6.PMID: 11597539 [PubMed - indexed for MEDLINE]Related articles

Androgen blocks apoptosis of hormone-dependent prostate cancer cells.

Kimura K, Markowski M, Bowen C, Gelmann EP.

Cancer Res. 2001 Jul 15;61(14):5611-8.PMID: 11454715 [PubMed - indexed for MEDLINE]Related articlesFree article

Design of the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial.

Prorok PC, Andriole GL, Bresalier RS, Buys SS, Chia D, Crawford ED, Fogel R, Gelmann EP, Gilbert F, Hasson MA, Hayes RB, Johnson CC, Mandel JS, Oberman A, O'Brien B, Oken MM, Rafla S, Reding D, Rutt W, Weissfeld JL, Yokochi L, Gohagan JK; Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial Project Team.

Control Clin Trials. 2000 Dec;21(6 Suppl):273S-309S.PMID: 11189684 [PubMed - indexed for MEDLINE]Related articles

Loss of NKX3.1 expression in human prostate cancers correlates with tumor progression.

Bowen C, Bubendorf L, Voeller HJ, Slack R, Willi N, Sauter G, Gasser TC, Koivisto P, Lack EE, Kononen J, Kallioniemi OP, Gelmann EP.

Cancer Res. 2000 Nov 1;60(21):6111-5.PMID: 11085535 [PubMed - indexed for MEDLINE]Related articlesFree article

Beta-catenin affects androgen receptor transcriptional activity and ligand specificity.

Truica CI, Byers S, Gelmann EP.

Cancer Res. 2000 Sep 1;60(17):4709-13.PMID: 10987273 [PubMed - indexed for MEDLINE]Related articlesFree article