PubMed

The signaling function of the IL-13Ralpha2 receptor in the development of gastrointestinal fibrosis and cancer surveillance.

Strober W, Kitani A, Fichtner-Feigl S, Fuss IJ.

Curr Mol Med. 2009 Aug;9(6):740-50.PMID: 19689301 [PubMed - in process]Related articles

Isolation of whole mononuclear cells from peripheral blood and cord blood.

Fuss IJ, Kanof ME, Smith PD, Zola H.

Curr Protoc Immunol. 2009 Apr;Chapter 7:Unit7.1.PMID: 19347849 [PubMed - indexed for MEDLINE]Related articles

The role of IL-13 and NK T cells in experimental and human ulcerative colitis.

Fuss IJ, Strober W.

Mucosal Immunol. 2008 Nov;1 Suppl 1:S31-3. Review.PMID: 19079225 [PubMed - indexed for MEDLINE]Related articles

Successful granulocyte-colony stimulating factor treatment of Crohn's disease is associated with the appearance of circulating interleukin-10-producing T cells and increased lamina propria plasmacytoid dendritic cells.

Mannon PJ, Leon F, Fuss IJ, Walter BA, Begnami M, Quezado M, Yang Z, Yi C, Groden C, Friend J, Hornung RL, Brown M, Gurprasad S, Kelsall B, Strober W.

Clin Exp Immunol. 2009 Mar;155(3):447-56. Epub 2008 Dec 15.PMID: 19094118 [PubMed - indexed for MEDLINE]Related articles

Increased expression of the tight junction molecule claudin-18 A1 in both experimental colitis and ulcerative colitis.

Zwiers A, Fuss IJ, Leijen S, Mulder CJ, Kraal G, Bouma G.

Inflamm Bowel Dis. 2008 Dec;14(12):1652-9.PMID: 18831034 [PubMed - indexed for MEDLINE]Related articlesFree article

Is the Th1/Th2 paradigm of immune regulation applicable to IBD?

Fuss IJ.

Inflamm Bowel Dis. 2008 Oct;14 Suppl 2:S110-2. No abstract available. Erratum in: Inflamm Bowel Dis. 2009 Sep;15(9):1438-47. PMID: 18816734 [PubMed - in process]Related articlesFree article

A transient breach in the epithelial barrier leads to regulatory T-cell generation and resistance to experimental colitis.

Boirivant M, Amendola A, Butera A, Sanchez M, Xu L, Marinaro M, Kitani A, Di Giacinto C, Strober W, Fuss IJ.

Gastroenterology. 2008 Nov;135(5):1612-1623.e5. Epub 2008 Aug 5.PMID: 18765239 [PubMed - indexed for MEDLINE]Related articles

Induction of TNBS colitis in mice.

Scheiffele F, Fuss IJ.

Curr Protoc Immunol. 2002 Aug;Chapter 15:Unit 15.19.PMID: 18432874 [PubMed - indexed for MEDLINE]Related articles

Notch1 signaling and regulatory T cell function.

Asano N, Watanabe T, Kitani A, Fuss IJ, Strober W.

J Immunol. 2008 Mar 1;180(5):2796-804.PMID: 18292500 [PubMed - indexed for MEDLINE]Related articlesFree article

Muramyl dipeptide activation of nucleotide-binding oligomerization domain 2 protects mice from experimental colitis.

Watanabe T, Asano N, Murray PJ, Ozato K, Tailor P, Fuss IJ, Kitani A, Strober W.

J Clin Invest. 2008 Feb;118(2):545-59.PMID: 18188453 [PubMed - indexed for MEDLINE]Related articlesFree article

NOD2 transgenic mice exhibit enhanced MDP-mediated down-regulation of TLR2 responses and resistance to colitis induction.

Yang Z, Fuss IJ, Watanabe T, Asano N, Davey MP, Rosenbaum JT, Strober W, Kitani A.

Gastroenterology. 2007 Nov;133(5):1510-21. Epub 2007 Jul 25.PMID: 17915219 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of IL-13 triggers TGF-beta1-dependent tissue fibrosis in chronic 2,4,6-trinitrobenzene sulfonic acid colitis.

Fichtner-Feigl S, Fuss IJ, Young CA, Watanabe T, Geissler EK, Schlitt HJ, Kitani A, Strober W.

J Immunol. 2007 May 1;178(9):5859-70.PMID: 17442970 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired regulation of NF-kappaB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice.

Zhang J, Stirling B, Temmerman ST, Ma CA, Fuss IJ, Derry JM, Jain A.

J Clin Invest. 2006 Nov;116(11):3042-9. Epub 2006 Oct 19.PMID: 17053834 [PubMed - indexed for MEDLINE]Related articlesFree article

Excess IL-12 but not IL-23 accompanies the inflammatory bowel disease associated with common variable immunodeficiency.

Mannon PJ, Fuss IJ, Dill S, Friend J, Groden C, Hornung R, Yang Z, Yi C, Quezado M, Brown M, Strober W.

Gastroenterology. 2006 Sep;131(3):748-56.PMID: 16952544 [PubMed - indexed for MEDLINE]Related articles

Nucleotide binding oligomerization domain 2 deficiency leads to dysregulated TLR2 signaling and induction of antigen-specific colitis.

Watanabe T, Kitani A, Murray PJ, Wakatsuki Y, Fuss IJ, Strober W.

Immunity. 2006 Sep;25(3):473-85. Epub 2006 Aug 31.PMID: 16949315 [PubMed - indexed for MEDLINE]Related articles

Experimental models of mucosal inflammation.

Strober W, Fuss IJ.

Adv Exp Med Biol. 2006;579:55-97. Review. No abstract available. PMID: 16620012 [PubMed - indexed for MEDLINE]Related articles

Both IL-12p70 and IL-23 are synthesized during active Crohn's disease and are down-regulated by treatment with anti-IL-12 p40 monoclonal antibody.

Fuss IJ, Becker C, Yang Z, Groden C, Hornung RL, Heller F, Neurath MF, Strober W, Mannon PJ.

Inflamm Bowel Dis. 2006 Jan;12(1):9-15.PMID: 16374252 [PubMed - indexed for MEDLINE]Related articles

Treatment of murine Th1- and Th2-mediated inflammatory bowel disease with NF-kappa B decoy oligonucleotides.

Fichtner-Feigl S, Fuss IJ, Preiss JC, Strober W, Kitani A.

J Clin Invest. 2005 Nov;115(11):3057-71. Epub 2005 Oct 20.PMID: 16239967 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulatory cells induced by feeding TNP-haptenated colonic protein cross-protect mice from colitis induced by an unrelated hapten.

Boirivant M, Strober W, Fuss IJ.

Inflamm Bowel Dis. 2005 Jan;11(1):48-55.PMID: 15674113 [PubMed - indexed for MEDLINE]Related articles

Anti-interleukin-12 antibody for active Crohn's disease.

Mannon PJ, Fuss IJ, Mayer L, Elson CO, Sandborn WJ, Present D, Dolin B, Goodman N, Groden C, Hornung RL, Quezado M, Yang Z, Neurath MF, Salfeld J, Veldman GM, Schwertschlag U, Strober W; Anti-IL-12 Crohn's Disease Study Group.

N Engl J Med. 2004 Nov 11;351(20):2069-79. Erratum in: N Engl J Med. 2005 Mar 24;352(12):1276. Yang, Zhiqiong [added]. PMID: 15537905 [PubMed - indexed for MEDLINE]Related articlesFree article

Nonclassical CD1d-restricted NK T cells that produce IL-13 characterize an atypical Th2 response in ulcerative colitis.

Fuss IJ, Heller F, Boirivant M, Leon F, Yoshida M, Fichtner-Feigl S, Yang Z, Exley M, Kitani A, Blumberg RS, Mannon P, Strober W.

J Clin Invest. 2004 May;113(10):1490-7.PMID: 15146247 [PubMed - indexed for MEDLINE]Related articlesFree article

Treatment of ulcerative colitis with infliximab: are we there yet?

Fuss IJ.

J Pediatr Gastroenterol Nutr. 2004 Mar;38(3):247-9. No abstract available. PMID: 15076622 [PubMed - indexed for MEDLINE]Related articles

Specific regulation of T helper cell 1-mediated murine colitis by CEACAM1.

Iijima H, Neurath MF, Nagaishi T, Glickman JN, Nieuwenhuis EE, Nakajima A, Chen D, Fuss IJ, Utku N, Lewicki DN, Becker C, Gallagher TM, Holmes KV, Blumberg RS.

J Exp Med. 2004 Feb 16;199(4):471-82.PMID: 14970176 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytokine network in inflammatory bowel disease.

Fuss IJ.

Curr Drug Targets Inflamm Allergy. 2003 Jun;2(2):101-12. Review.PMID: 14561161 [PubMed - indexed for MEDLINE]Related articles

Recent advances in the understanding of the induction and regulation of mucosal inflammation.

Strober W, Fuss IJ, Nakamura K, Kitani A.

J Gastroenterol. 2003 Mar;38 Suppl 15:55-8. Review. No abstract available. PMID: 12698873 [PubMed - indexed for MEDLINE]Related articles

Oxazolone colitis, a Th2 colitis model resembling ulcerative colitis, is mediated by IL-13-producing NK-T cells.

Heller F, Fuss IJ, Nieuwenhuis EE, Blumberg RS, Strober W.

Immunity. 2002 Nov;17(5):629-38.PMID: 12433369 [PubMed - indexed for MEDLINE]Related articles

An enteric helminth infection protects against an allergic response to dietary antigen.

Bashir ME, Andersen P, Fuss IJ, Shi HN, Nagler-Anderson C.

J Immunol. 2002 Sep 15;169(6):3284-92.PMID: 12218148 [PubMed - indexed for MEDLINE]Related articlesFree article

The immunology of mucosal models of inflammation.

Strober W, Fuss IJ, Blumberg RS.

Annu Rev Immunol. 2002;20:495-549. Epub 2001 Oct 4. Review.PMID: 11861611 [PubMed - indexed for MEDLINE]Related articles

The interrelated roles of TGF-beta and IL-10 in the regulation of experimental colitis.

Fuss IJ, Boirivant M, Lacy B, Strober W.

J Immunol. 2002 Jan 15;168(2):900-8.PMID: 11777988 [PubMed - indexed for MEDLINE]Related articlesFree article

Oral administration of recombinant cholera toxin subunit B inhibits IL-12-mediated murine experimental (trinitrobenzene sulfonic acid) colitis.

Boirivant M, Fuss IJ, Ferroni L, De Pascale M, Strober W.

J Immunol. 2001 Mar 1;166(5):3522-32.PMID: 11207312 [PubMed - indexed for MEDLINE]Related articlesFree article

Treatment of experimental (Trinitrobenzene sulfonic acid) colitis by intranasal administration of transforming growth factor (TGF)-beta1 plasmid: TGF-beta1-mediated suppression of T helper cell type 1 response occurs by interleukin (IL)-10 induction and IL-12 receptor beta2 chain downregulation.

Kitani A, Fuss IJ, Nakamura K, Schwartz OM, Usui T, Strober W.

J Exp Med. 2000 Jul 3;192(1):41-52.PMID: 10880525 [PubMed - indexed for MEDLINE]Related articlesFree article

Whipple's disease in a father-daughter pair.

Dykman DD, Cuccherini BA, Fuss IJ, Blum LW, Woodward JE, Strober W.

Dig Dis Sci. 1999 Dec;44(12):2542-4. No abstract available. PMID: 10630510 [PubMed - indexed for MEDLINE]Related articles

Anti-interleukin 12 treatment regulates apoptosis of Th1 T cells in experimental colitis in mice.

Fuss IJ, Marth T, Neurath MF, Pearlstein GR, Jain A, Strober W.

Gastroenterology. 1999 Nov;117(5):1078-88.PMID: 10535870 [PubMed - indexed for MEDLINE]Related articles

Intestinal lymphangiectasia, a disease characterized by selective loss of naive CD45RA+ lymphocytes into the gastrointestinal tract.

Fuss IJ, Strober W, Cuccherini BA, Pearlstein GR, Bossuyt X, Brown M, Fleisher TA, Horgan K.

Eur J Immunol. 1998 Dec;28(12):4275-85.PMID: 9862365 [PubMed - indexed for MEDLINE]Related articles

Mucosal immunoregulation and inflammatory bowel disease: new insights from murine models of inflammation.

Strober W, Fuss IJ, Ehrhardt RO, Neurath M, Boirivant M, Lúdvíksson BR.

Scand J Immunol. 1998 Nov;48(5):453-8. Review. No abstract available. PMID: 9822251 [PubMed - indexed for MEDLINE]Related articles

Oxazolone colitis: A murine model of T helper cell type 2 colitis treatable with antibodies to interleukin 4.

Boirivant M, Fuss IJ, Chu A, Strober W.

J Exp Med. 1998 Nov 16;188(10):1929-39.PMID: 9815270 [PubMed - indexed for MEDLINE]Related articlesFree article

The pathogenesis of mucosal inflammation in murine models of inflammatory bowel disease and Crohn disease.

Strober W, Lúdvíksson BR, Fuss IJ.

Ann Intern Med. 1998 May 15;128(10):848-56. Review.PMID: 9599198 [PubMed - indexed for MEDLINE]Related articlesFree article

Characteristic T helper 2 T cell cytokine abnormalities in autoimmune lymphoproliferative syndrome, a syndrome marked by defective apoptosis and humoral autoimmunity.

Fuss IJ, Strober W, Dale JK, Fritz S, Pearlstein GR, Puck JM, Lenardo MJ, Straus SE.

J Immunol. 1997 Feb 15;158(4):1912-8.PMID: 9029133 [PubMed - indexed for MEDLINE]Related articles

Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5.

Fuss IJ, Neurath M, Boirivant M, Klein JS, de la Motte C, Strong SA, Fiocchi C, Strober W.

J Immunol. 1996 Aug 1;157(3):1261-70.PMID: 8757634 [PubMed - indexed for MEDLINE]Related articles