PubMed

Germline polymorphisms in the one-carbon metabolism pathway and DNA methylation in colorectal cancer.

Hazra A, Fuchs CS, Kawasaki T, Kirkner GJ, Hunter DJ, Ogino S.

Cancer Causes Control. 2009 Nov 21. [Epub ahead of print]PMID: 19936946 [PubMed - as supplied by publisher]

KRAS Mutation in Stage III Colon Cancer and Clinical Outcome Following Intergroup Trial CALGB 89803.

Ogino S, Meyerhardt JA, Irahara N, Niedzwiecki D, Hollis D, Saltz LB, Mayer RJ, Schaefer P, Whittom R, Hantel A, Benson AB 3rd, Goldberg RM, Bertagnolli MM, Fuchs CS; for the Cancer and Leukemia Group B, North Central Cancer Treatment Group, Canadian Cancer Society Research Institute, Southwest Oncology Group.

Clin Cancer Res. 2009 Nov 24. [Epub ahead of print]PMID: 19934290 [PubMed - as supplied by publisher]

Efficacy and safety of gemcitabine, oxaliplatin, and bevacizumab in advanced biliary-tract cancers and correlation of changes in 18-fluorodeoxyglucose PET with clinical outcome: a phase 2 study.

Zhu AX, Meyerhardt JA, Blaszkowsky LS, Kambadakone AR, Muzikansky A, Zheng H, Clark JW, Abrams TA, Chan JA, Enzinger PC, Bhargava P, Kwak EL, Allen JN, Jain SR, Stuart K, Horgan K, Sheehan S, Fuchs CS, Ryan DP, Sahani DV.

Lancet Oncol. 2009 Nov 19. [Epub ahead of print]PMID: 19932054 [PubMed - as supplied by publisher]

A randomized trial on folic acid supplementation and risk of recurrent colorectal adenoma.

Wu K, Platz EA, Willett WC, Fuchs CS, Selhub J, Rosner BA, Hunter DJ, Giovannucci E.

Am J Clin Nutr. 2009 Dec;90(6):1623-31. Epub 2009 Oct 28.PMID: 19864409 [PubMed - in process]Related articles

Lymphocytic reaction to colorectal cancer is associated with longer survival, independent of lymph node count, microsatellite instability, and CpG island methylator phenotype.

Ogino S, Nosho K, Irahara N, Meyerhardt JA, Baba Y, Shima K, Glickman JN, Ferrone CR, Mino-Kenudson M, Tanaka N, Dranoff G, Giovannucci EL, Fuchs CS.

Clin Cancer Res. 2009 Oct 15;15(20):6412-20. Epub 2009 Oct 13.PMID: 19825961 [PubMed - in process]Related articles

History of peptic ulcer disease and pancreatic cancer risk in men.

Bao Y, Spiegelman D, Li R, Giovannucci E, Fuchs CS, Michaud DS.

Gastroenterology. 2009 Oct 7. [Epub ahead of print]PMID: 19818786 [PubMed - as supplied by publisher]Related articles

Negative Lymph Node Count Is Associated With Survival of Colorectal Cancer Patients, Independent of Tumoral Molecular Alterations and Lymphocytic Reaction.

Ogino S, Nosho K, Irahara N, Shima K, Baba Y, Kirkner GJ, Mino-Kenudson M, Giovannucci EL, Meyerhardt JA, Fuchs CS.

Am J Gastroenterol. 2009 Oct 6. [Epub ahead of print]PMID: 19809407 [PubMed - as supplied by publisher]Related articles

CDK8 expression in 470 colorectal cancers in relation to beta-catenin activation, other molecular alterations and patient survival.

Firestein R, Shima K, Nosho K, Irahara N, Baba Y, Bojarski E, Giovannucci EL, Fuchs CS, Ogino S.

Int J Cancer. 2009 Sep 29. [Epub ahead of print]PMID: 19790197 [PubMed - as supplied by publisher]Related articles

Vitamin D receptor expression is associated with PIK3CA and KRAS mutations in colorectal cancer.

Kure S, Nosho K, Baba Y, Irahara N, Shima K, Ng K, Meyerhardt JA, Giovannucci EL, Fuchs CS, Ogino S.

Cancer Epidemiol Biomarkers Prev. 2009 Oct;18(10):2765-72. Epub 2009 Sep 29.PMID: 19789368 [PubMed - in process]Related articles

p21 expression in colon cancer and modifying effects of patient age and body mass index on prognosis.

Ogino S, Nosho K, Shima K, Baba Y, Irahara N, Kirkner GJ, Hazra A, De Vivo I, Giovannucci EL, Meyerhardt JA, Fuchs CS.

Cancer Epidemiol Biomarkers Prev. 2009 Sep;18(9):2513-21. Epub 2009 Sep 1.PMID: 19723919 [PubMed - in process]Related articles

Cumulative risk of colon cancer up to age 70 years by risk factor status using data from the Nurses' Health Study.

Wei EK, Colditz GA, Giovannucci EL, Fuchs CS, Rosner BA.

Am J Epidemiol. 2009 Oct 1;170(7):863-72. Epub 2009 Sep 1.PMID: 19723749 [PubMed - indexed for MEDLINE]Related articles

Interaction of molecular markers and physical activity on mortality in patients with colon cancer.

Meyerhardt JA, Ogino S, Kirkner GJ, Chan AT, Wolpin B, Ng K, Nosho K, Shima K, Giovannucci EL, Loda M, Fuchs CS.

Clin Cancer Res. 2009 Sep 15;15(18):5931-6. Epub 2009 Sep 1.PMID: 19723652 [PubMed - in process]Related articles

Prognostic significance and molecular associations of 18q loss of heterozygosity: a cohort study of microsatellite stable colorectal cancers.

Ogino S, Nosho K, Irahara N, Shima K, Baba Y, Kirkner GJ, Meyerhardt JA, Fuchs CS.

J Clin Oncol. 2009 Sep 20;27(27):4591-8. Epub 2009 Aug 24.PMID: 19704056 [PubMed - indexed for MEDLINE]Related articles

Prospective study of predictors of vitamin D status and survival in patients with colorectal cancer.

Ng K, Wolpin BM, Meyerhardt JA, Wu K, Chan AT, Hollis BW, Giovannucci EL, Stampfer MJ, Willett WC, Fuchs CS.

Br J Cancer. 2009 Sep 15;101(6):916-23. Epub 2009 Aug 18.PMID: 19690551 [PubMed - indexed for MEDLINE]Related articles

A prospective cohort study shows unique epigenetic, genetic, and prognostic features of synchronous colorectal cancers.

Nosho K, Kure S, Irahara N, Shima K, Baba Y, Spiegelman D, Meyerhardt JA, Giovannucci EL, Fuchs CS, Ogino S.

Gastroenterology. 2009 Nov;137(5):1609-20.e1-3. Epub 2009 Aug 14.PMID: 19686742 [PubMed - in process]Related articles

Aspirin use and survival after diagnosis of colorectal cancer.

Chan AT, Ogino S, Fuchs CS.

JAMA. 2009 Aug 12;302(6):649-58.PMID: 19671906 [PubMed - indexed for MEDLINE]Related articles

Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer.

Amundadottir L, Kraft P, Stolzenberg-Solomon RZ, Fuchs CS, Petersen GM, Arslan AA, Bueno-de-Mesquita HB, Gross M, Helzlsouer K, Jacobs EJ, LaCroix A, Zheng W, Albanes D, Bamlet W, Berg CD, Berrino F, Bingham S, Buring JE, Bracci PM, Canzian F, Clavel-Chapelon F, Clipp S, Cotterchio M, de Andrade M, Duell EJ, Fox JW Jr, Gallinger S, Gaziano JM, Giovannucci EL, Goggins M, González CA, Hallmans G, Hankinson SE, Hassan M, Holly EA, Hunter DJ, Hutchinson A, Jackson R, Jacobs KB, Jenab M, Kaaks R, Klein AP, Kooperberg C, Kurtz RC, Li D, Lynch SM, Mandelson M, McWilliams RR, Mendelsohn JB, Michaud DS, Olson SH, Overvad K, Patel AV, Peeters PH, Rajkovic A, Riboli E, Risch HA, Shu XO, Thomas G, Tobias GS, Trichopoulos D, Van Den Eeden SK, Virtamo J, Wactawski-Wende J, Wolpin BM, Yu H, Yu K, Zeleniuch-Jacquotte A, Chanock SJ, Hartge P, Hoover RN.

Nat Genet. 2009 Sep;41(9):986-90. Epub 2009 Aug 2.PMID: 19648918 [PubMed - indexed for MEDLINE]Related articles

Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer.

Souglakos J, Philips J, Wang R, Marwah S, Silver M, Tzardi M, Silver J, Ogino S, Hooshmand S, Kwak E, Freed E, Meyerhardt JA, Saridaki Z, Georgoulias V, Finkelstein D, Fuchs CS, Kulke MH, Shivdasani RA.

Br J Cancer. 2009 Aug 4;101(3):465-72. Epub 2009 Jul 14.PMID: 19603024 [PubMed - indexed for MEDLINE]Related articles

Passive smoking and pancreatic cancer in women: a prospective cohort study.

Bao Y, Giovannucci E, Fuchs CS, Michaud DS.

Cancer Epidemiol Biomarkers Prev. 2009 Aug;18(8):2292-6. Epub 2009 Jul 14.PMID: 19602702 [PubMed - indexed for MEDLINE]Related articles

Relationship of CDX2 loss with molecular features and prognosis in colorectal cancer.

Baba Y, Nosho K, Shima K, Freed E, Irahara N, Philips J, Meyerhardt JA, Hornick JL, Shivdasani RA, Fuchs CS, Ogino S.

Clin Cancer Res. 2009 Jul 15;15(14):4665-73. Epub 2009 Jul 7.PMID: 19584150 [PubMed - indexed for MEDLINE]Related articles

Serum alpha-fetoprotein response as a surrogate for clinical outcome in patients receiving systemic therapy for advanced hepatocellular carcinoma.

Vora SR, Zheng H, Stadler ZK, Fuchs CS, Zhu AX.

Oncologist. 2009 Jul;14(7):717-25. Epub 2009 Jul 6.PMID: 19581525 [PubMed - indexed for MEDLINE]Related articles

A cohort study of cyclin D1 expression and prognosis in 602 colon cancer cases.

Ogino S, Nosho K, Irahara N, Kure S, Shima K, Baba Y, Toyoda S, Chen L, Giovannucci EL, Meyerhardt JA, Fuchs CS.

Clin Cancer Res. 2009 Jul 1;15(13):4431-8. Epub 2009 Jun 23.PMID: 19549773 [PubMed - indexed for MEDLINE]Related articles

A cohort study of STMN1 expression in colorectal cancer: body mass index and prognosis.

Ogino S, Nosho K, Baba Y, Kure S, Shima K, Irahara N, Toyoda S, Chen L, Kirkner GJ, Wolpin BM, Chan AT, Giovannucci EL, Fuchs CS.

Am J Gastroenterol. 2009 Aug;104(8):2047-56. Epub 2009 Jun 9.PMID: 19513025 [PubMed - indexed for MEDLINE]Related articles

A cohort study of p27 localization in colon cancer, body mass index, and patient survival.

Ogino S, Shima K, Nosho K, Irahara N, Baba Y, Wolpin BM, Giovannucci EL, Meyerhardt JA, Fuchs CS.

Cancer Epidemiol Biomarkers Prev. 2009 Jun;18(6):1849-58.PMID: 19505918 [PubMed - indexed for MEDLINE]Related articles

Efficacy, safety, and potential biomarkers of sunitinib monotherapy in advanced hepatocellular carcinoma: a phase II study.

Zhu AX, Sahani DV, Duda DG, di Tomaso E, Ancukiewicz M, Catalano OA, Sindhwani V, Blaszkowsky LS, Yoon SS, Lahdenranta J, Bhargava P, Meyerhardt J, Clark JW, Kwak EL, Hezel AF, Miksad R, Abrams TA, Enzinger PC, Fuchs CS, Ryan DP, Jain RK.

J Clin Oncol. 2009 Jun 20;27(18):3027-35. Epub 2009 May 26.PMID: 19470923 [PubMed - indexed for MEDLINE]Related articles

DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer.

Nosho K, Shima K, Irahara N, Kure S, Baba Y, Kirkner GJ, Chen L, Gokhale S, Hazra A, Spiegelman D, Giovannucci EL, Jaenisch R, Fuchs CS, Ogino S.

Clin Cancer Res. 2009 Jun 1;15(11):3663-71. Epub 2009 May 26.PMID: 19470733 [PubMed - indexed for MEDLINE]Related articles

SIRT1 histone deacetylase expression is associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.

Nosho K, Shima K, Irahara N, Kure S, Firestein R, Baba Y, Toyoda S, Chen L, Hazra A, Giovannucci EL, Fuchs CS, Ogino S.

Mod Pathol. 2009 Jul;22(7):922-32. Epub 2009 May 8.PMID: 19430421 [PubMed - indexed for MEDLINE]Related articles

Aurora-A expression is independently associated with chromosomal instability in colorectal cancer.

Baba Y, Nosho K, Shima K, Irahara N, Kure S, Toyoda S, Kirkner GJ, Goel A, Fuchs CS, Ogino S.

Neoplasia. 2009 May;11(5):418-25.PMID: 19412426 [PubMed - indexed for MEDLINE]Related articlesFree article

Body mass index and Barrett's oesophagus in women.

Jacobson BC, Chan AT, Giovannucci EL, Fuchs CS.

Gut. 2009 Nov;58(11):1460-6. Epub 2009 Mar 30.PMID: 19336423 [PubMed - in process]Related articles

ABO blood group and the risk of pancreatic cancer.

Wolpin BM, Chan AT, Hartge P, Chanock SJ, Kraft P, Hunter DJ, Giovannucci EL, Fuchs CS.

J Natl Cancer Inst. 2009 Mar 18;101(6):424-31. Epub 2009 Mar 10.PMID: 19276450 [PubMed - indexed for MEDLINE]Related articles

Alcohol intake and pancreatic cancer risk: a pooled analysis of fourteen cohort studies.

Genkinger JM, Spiegelman D, Anderson KE, Bergkvist L, Bernstein L, van den Brandt PA, English DR, Freudenheim JL, Fuchs CS, Giles GG, Giovannucci E, Hankinson SE, Horn-Ross PL, Leitzmann M, Männistö S, Marshall JR, McCullough ML, Miller AB, Reding DJ, Robien K, Rohan TE, Schatzkin A, Stevens VL, Stolzenberg-Solomon RZ, Verhage BA, Wolk A, Ziegler RG, Smith-Warner SA.

Cancer Epidemiol Biomarkers Prev. 2009 Mar;18(3):765-76. Epub 2009 Mar 3.PMID: 19258474 [PubMed - indexed for MEDLINE]Related articles

PIK3CA mutation is associated with poor prognosis among patients with curatively resected colon cancer.

Ogino S, Nosho K, Kirkner GJ, Shima K, Irahara N, Kure S, Chan AT, Engelman JA, Kraft P, Cantley LC, Giovannucci EL, Fuchs CS.

J Clin Oncol. 2009 Mar 20;27(9):1477-84. Epub 2009 Feb 23.PMID: 19237633 [PubMed - indexed for MEDLINE]Related articles

Colorectal cancer expression of peroxisome proliferator-activated receptor gamma (PPARG, PPARgamma) is associated with good prognosis.

Ogino S, Shima K, Baba Y, Nosho K, Irahara N, Kure S, Chen L, Toyoda S, Kirkner GJ, Wang YL, Giovannucci EL, Fuchs CS.

Gastroenterology. 2009 Apr;136(4):1242-50. Epub 2008 Dec 24.PMID: 19186181 [PubMed - indexed for MEDLINE]Related articles

Weekly docetaxel, cisplatin, and irinotecan (TPC): results of a multicenter phase II trial in patients with metastatic esophagogastric cancer.

Enzinger PC, Ryan DP, Clark JW, Muzikansky A, Earle CC, Kulke MH, Meyerhardt JA, Blaszkowsky LS, Zhu AX, Fidias P, Vincitore MM, Mayer RJ, Fuchs CS.

Ann Oncol. 2009 Mar;20(3):475-80. Epub 2009 Jan 12.PMID: 19139178 [PubMed - indexed for MEDLINE]Related articles

O6-methylguanine DNA methyltransferase deficiency and response to temozolomide-based therapy in patients with neuroendocrine tumors.

Kulke MH, Hornick JL, Frauenhoffer C, Hooshmand S, Ryan DP, Enzinger PC, Meyerhardt JA, Clark JW, Stuart K, Fuchs CS, Redston MS.

Clin Cancer Res. 2009 Jan 1;15(1):338-45.PMID: 19118063 [PubMed - indexed for MEDLINE]Related articles

JC virus T-antigen in colorectal cancer is associated with p53 expression and chromosomal instability, independent of CpG island methylator phenotype.

Nosho K, Shima K, Kure S, Irahara N, Baba Y, Chen L, Kirkner GJ, Fuchs CS, Ogino S.

Neoplasia. 2009 Jan;11(1):87-95.PMID: 19107235 [PubMed - indexed for MEDLINE]Related articlesFree article

Cyclooxygenase-2 expression is an independent predictor of poor prognosis in colon cancer.

Ogino S, Kirkner GJ, Nosho K, Irahara N, Kure S, Shima K, Hazra A, Chan AT, Dehari R, Giovannucci EL, Fuchs CS.

Clin Cancer Res. 2008 Dec 15;14(24):8221-7.PMID: 19088039 [PubMed - indexed for MEDLINE]Related articles

Plasma insulin-like growth factors, insulin-like binding protein-3, and outcome in metastatic colorectal cancer: results from intergroup trial N9741.

Fuchs CS, Goldberg RM, Sargent DJ, Meyerhardt JA, Wolpin BM, Green EM, Pitot HC, Pollak M.

Clin Cancer Res. 2008 Dec 15;14(24):8263-9. Epub 2008 Dec 10.PMID: 19073970 [PubMed - indexed for MEDLINE]Related articles

Insulin, the insulin-like growth factor axis, and mortality in patients with nonmetastatic colorectal cancer.

Wolpin BM, Meyerhardt JA, Chan AT, Ng K, Chan JA, Wu K, Pollak MN, Giovannucci EL, Fuchs CS.

J Clin Oncol. 2009 Jan 10;27(2):176-85. Epub 2008 Dec 8.PMID: 19064975 [PubMed - indexed for MEDLINE]Related articles

Oral mTOR inhibitor everolimus in patients with gemcitabine-refractory metastatic pancreatic cancer.

Wolpin BM, Hezel AF, Abrams T, Blaszkowsky LS, Meyerhardt JA, Chan JA, Enzinger PC, Allen B, Clark JW, Ryan DP, Fuchs CS.

J Clin Oncol. 2009 Jan 10;27(2):193-8. Epub 2008 Dec 1.PMID: 19047305 [PubMed - indexed for MEDLINE]Related articles

A cohort study of tumoral LINE-1 hypomethylation and prognosis in colon cancer.

Ogino S, Nosho K, Kirkner GJ, Kawasaki T, Chan AT, Schernhammer ES, Giovannucci EL, Fuchs CS.

J Natl Cancer Inst. 2008 Dec 3;100(23):1734-8. Epub 2008 Nov 25.PMID: 19033568 [PubMed - indexed for MEDLINE]Related articles

Comprehensive biostatistical analysis of CpG island methylator phenotype in colorectal cancer using a large population-based sample.

Nosho K, Irahara N, Shima K, Kure S, Kirkner GJ, Schernhammer ES, Hazra A, Hunter DJ, Quackenbush J, Spiegelman D, Giovannucci EL, Fuchs CS, Ogino S.

PLoS One. 2008;3(11):e3698. Epub 2008 Nov 12.PMID: 19002263 [PubMed - indexed for MEDLINE]Related articlesFree article

Five-year data and prognostic factor analysis of oxaliplatin and irinotecan combinations for advanced colorectal cancer: N9741.

Sanoff HK, Sargent DJ, Campbell ME, Morton RF, Fuchs CS, Ramanathan RK, Williamson SK, Findlay BP, Pitot HC, Goldberg RM.

J Clin Oncol. 2008 Dec 10;26(35):5721-7. Epub 2008 Nov 10.PMID: 19001325 [PubMed - indexed for MEDLINE]Related articles

Cyclin D1 is frequently overexpressed in microsatellite unstable colorectal cancer, independent of CpG island methylator phenotype.

Nosho K, Kawasaki T, Chan AT, Ohnishi M, Suemoto Y, Kirkner GJ, Fuchs CS, Ogino S.

Histopathology. 2008 Nov;53(5):588-98.PMID: 18983468 [PubMed - indexed for MEDLINE]Related articlesFree article

Cohort study of fatty acid synthase expression and patient survival in colon cancer.

Ogino S, Nosho K, Meyerhardt JA, Kirkner GJ, Chan AT, Kawasaki T, Giovannucci EL, Loda M, Fuchs CS.

J Clin Oncol. 2008 Dec 10;26(35):5713-20. Epub 2008 Oct 27.PMID: 18955444 [PubMed - indexed for MEDLINE]Related articles

Esophageal cancer.

Ajani JA, Barthel JS, Bekaii-Saab T, Bentrem DJ, D'Amico TA, Fuchs CS, Gerdes H, Hayman JA, Hazard L, Ilson DH, Kleinberg LR, McAleer MF, Meropol NJ, Mulcahy MF, Orringer MB, Osarogiagbon RU, Posey JA, Sasson AR, Scott WJ, Shibata S, Strong VE, Swisher SG, Washington MK, Willett C, Wood DE, Wright CD, Yang G; NCCN Esophageal Cancer Panel.

J Natl Compr Canc Netw. 2008 Oct;6(9):818-49. No abstract available. PMID: 18926093 [PubMed - indexed for MEDLINE]Related articles

A prospective study of dietary folate and vitamin B and colon cancer according to microsatellite instability and KRAS mutational status.

Schernhammer ES, Giovannuccci E, Fuchs CS, Ogino S.

Cancer Epidemiol Biomarkers Prev. 2008 Oct;17(10):2895-8.PMID: 18843035 [PubMed - indexed for MEDLINE]Related articlesFree article

CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer.

Ogino S, Nosho K, Kirkner GJ, Kawasaki T, Meyerhardt JA, Loda M, Giovannucci EL, Fuchs CS.

Gut. 2009 Jan;58(1):90-6. Epub 2008 Oct 2.PMID: 18832519 [PubMed - indexed for MEDLINE]Related articles

Sign of Leser-Trélat in newly diagnosed advanced gastric adenocarcinoma.

Nanda A, Mamon HJ, Fuchs CS.

J Clin Oncol. 2008 Oct 20;26(30):4992-3. Epub 2008 Sep 22. No abstract available. PMID: 18809604 [PubMed - indexed for MEDLINE]Related articles

CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity.

Firestein R, Bass AJ, Kim SY, Dunn IF, Silver SJ, Guney I, Freed E, Ligon AH, Vena N, Ogino S, Chheda MG, Tamayo P, Finn S, Shrestha Y, Boehm JS, Jain S, Bojarski E, Mermel C, Barretina J, Chan JA, Baselga J, Tabernero J, Root DE, Fuchs CS, Loda M, Shivdasani RA, Meyerson M, Hahn WC.

Nature. 2008 Sep 25;455(7212):547-51. Epub 2008 Sep 14.PMID: 18794900 [PubMed - indexed for MEDLINE]Related articlesFree article