PubMed

Novel Obesity Risk Loci Do Not Determine Distribution of Body Fat Depots: A Whole-body MRI/MRS study.

Haupt A, Thamer C, Heni M, Machicao F, Machann J, Schick F, Stefan N, Fritsche A, Häring HU, Staiger H.

Obesity (Silver Spring). 2009 Nov 12. [Epub ahead of print]PMID: 19910938 [PubMed - as supplied by publisher]Related articles

Circulating Palmitoleate strongly and independently predicts Insulin Sensitivity in Humans.

Stefan N, Kantartzis K, Celebi N, Staiger H, Machann J, Schick F, Cegan A, Elcnerova M, Schleicher E, Fritsche A, Häring HU.

Diabetes Care. 2009 Nov 4. [Epub ahead of print]PMID: 19889804 [PubMed - as supplied by publisher]Related articles

Medical antihyperglycaemic treatment of type 2 diabetes mellitus: update of the evidence-based guideline of the German Diabetes Association.

Matthaei S, Bierwirth R, Fritsche A, Gallwitz B, Häring HU, Joost HG, Kellerer M, Kloos Ch, Kunt T, Nauck M, Schernthaner G, Siegel E, Thienel F.

Exp Clin Endocrinol Diabetes. 2009 Oct;117(9):522-57. Epub 2009 Oct 29. No abstract available. PMID: 19876795 [PubMed - in process]Related articles

The insulin effect on cerebrocortical theta activity is associated with serum concentrations of saturated nonesterified Fatty acids.

Tschritter O, Preissl H, Hennige AM, Sartorius T, Grichisch Y, Stefan N, Guthoff M, Düsing S, Machann J, Schleicher E, Cegan A, Birbaumer N, Fritsche A, Häring HU.

J Clin Endocrinol Metab. 2009 Nov;94(11):4600-7. Epub 2009 Oct 9.PMID: 19820026 [PubMed - in process]Related articles

A Combined Risk Allele Score of Eight Type 2 Diabetes Genes Is Associated With Reduced First Phase Glucose Stimulated Insulin Secretion During Hyperglycemic Clamps.

't Hart LM, Simonis-Bik AM, Nijpels G, van Haeften TW, Schäfer SA, Houwing-Duistermaat JJ, Boomsma DI, Groenewoud MJ, Reiling E, van Hove EC, Diamant M, Kramer MH, Heine RJ, Maassen JA, Kirchhoff K, Machicao F, Häring HU, Slagboom PE, Willemsen G, Eekhoff EM, de Geus EJ, Dekker JM, Fritsche A.

Diabetes. 2009 Oct 6. [Epub ahead of print]PMID: 19808892 [PubMed - as supplied by publisher]Related articles

Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients--EUGENE2 study.

Boesgaard TW, Gjesing AP, Grarup N, Rutanen J, Jansson PA, Hribal ML, Sesti G, Fritsche A, Stefan N, Staiger H, Häring H, Smith U, Laakso M, Pedersen O, Hansen T; EUGENE2 Consortium.

PLoS One. 2009 Sep 30;4(9):e7236.PMID: 19789630 [PubMed - in process]Related articlesFree article

Insulin-mediated cortical activity in the slow frequency range is diminished in obese mice and promotes physical inactivity.

Hennige AM, Sartorius T, Lutz SZ, Tschritter O, Preissl H, Hopp S, Fritsche A, Rammensee HG, Ruth P, Häring HU.

Diabetologia. 2009 Sep 15. [Epub ahead of print]PMID: 19756482 [PubMed - as supplied by publisher]Related articles

Pathomechanisms of type 2 diabetes genes.

Staiger H, Machicao F, Fritsche A, Häring HU.

Endocr Rev. 2009 Oct;30(6):557-85. Epub 2009 Sep 11.PMID: 19749172 [PubMed - in process]Related articles

Use of multiple metabolic and genetic markers to improve the prediction of type 2 diabetes: the EPIC-Potsdam Study.

Schulze MB, Weikert C, Pischon T, Bergmann MM, Al-Hasani H, Schleicher E, Fritsche A, Häring HU, Boeing H, Joost HG.

Diabetes Care. 2009 Nov;32(11):2116-9. Epub 2009 Aug 31.PMID: 19720844 [PubMed - in process]Related articles

High baseline vitamin C levels do not prevent a positive outcome of a lifestyle intervention.

Thamer C, Machicao F, Stefan N, Fritsche A, Häring HU.

Diabetes Care. 2009 Sep;32(9):e112. No abstract available. PMID: 19717817 [PubMed - indexed for MEDLINE]Related articles

Preliminary report: genetic variation within the GPBAR1 gene is not associated with metabolic traits in white subjects at an increased risk for type 2 diabetes mellitus.

Müssig K, Staiger H, Machicao F, Machann J, Schick F, Schäfer SA, Claussen CD, Holst JJ, Gallwitz B, Stefan N, Fritsche A, Häring HU.

Metabolism. 2009 Dec;58(12):1809-11. Epub 2009 Aug 28.PMID: 19716570 [PubMed - in process]Related articles

Common polymorphisms within the NR4A3 locus, encoding the orphan nuclear receptor Nor-1, are associated with enhanced beta-cell function in non-diabetic subjects.

Weyrich P, Staiger H, Stancáková A, Schäfer SA, Kirchhoff K, Ullrich S, Ranta F, Gallwitz B, Stefan N, Machicao F, Kuusisto J, Laakso M, Fritsche A, Häring HU.

BMC Med Genet. 2009 Aug 14;10:77.PMID: 19682370 [PubMed - indexed for MEDLINE]Related articlesFree article

Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene.

Kantartzis K, Peter A, Machicao F, Machann J, Wagner S, Königsrainer I, Königsrainer A, Schick F, Fritsche A, Häring HU, Stefan N.

Diabetes. 2009 Nov;58(11):2616-23. Epub 2009 Aug 3.PMID: 19651814 [PubMed - in process]Related articles

Insulin detemir causes increased symptom awareness during hypoglycaemia compared to human insulin.

Tschritter O, Schäfer SA, Klett J, Pfäfflin A, Häring HU, Hennige AM, Fritsche A.

Diabetes Obes Metab. 2009 Nov;11(11):1017-26. Epub 2009 Jul 23.PMID: 19650876 [PubMed - in process]Related articles

[Influence of acetabular cup design on the primary implant stability : An experimental and numerical analysis.]

Zietz C, Fritsche A, Kluess D, Mittelmeier W, Bader R.

Orthopade. 2009 Nov;38(11):1097-105. German. PMID: 19636530 [PubMed - in process]Related articles

Impact of variation near MC4R on whole-body fat distribution, liver fat, and weight loss.

Haupt A, Thamer C, Heni M, Tschritter O, Machann J, Schick F, Machicao F, Häring HU, Staiger H, Fritsche A.

Obesity (Silver Spring). 2009 Oct;17(10):1942-5. Epub 2009 Jul 30.PMID: 19629057 [PubMed - in process]Related articles

[Individualized prevention of type 2 diabetes]

Stefan N, Fritsche A, Häring HU.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2009 Jul;52(7):677-82. German. PMID: 19626284 [PubMed - indexed for MEDLINE]Related articles

High plasma fetuin-A is associated with increased carotid intima-media thickness in a middle-aged population.

Rittig K, Thamer C, Haupt A, Machann J, Peter A, Balletshofer B, Fritsche A, Haring HU, Stefan N.

Atherosclerosis. 2009 May 22. [Epub ahead of print] No abstract available. PMID: 19615685 [PubMed - as supplied by publisher]Related articles

[Fear of allowing sugar into the cell--case 05/2009. Comorbidity of diabetes mellitus and eating disorders]

Teufel M, Becker S, Martens U, Fritsche A, Matheis A, Zipfel S.

Dtsch Med Wochenschr. 2009 Jul;134(30):1520. Epub 2009 Jul 14. German. PMID: 19603367 [PubMed - indexed for MEDLINE]Related articles

Urinary free cortisone, but not cortisol, is associated with urine volume in severe obesity.

Müssig K, Remer T, Fritsche A, Häring HU, Maser-Gluth C.

Steroids. 2009 Sep;74(9):742-5. Epub 2009 Apr 2.PMID: 19541001 [PubMed - indexed for MEDLINE]Related articles

Effect of genetic variation in Kv1.3 on olfactory function.

Guthoff M, Tschritter O, Berg D, Liepelt I, Schulte C, Machicao F, Haering HU, Fritsche A.

Diabetes Metab Res Rev. 2009 Sep;25(6):523-7.PMID: 19489042 [PubMed - in process]Related articles

Intermuscular adipose tissue (IMAT): association with other adipose tissue compartments and insulin sensitivity.

Boettcher M, Machann J, Stefan N, Thamer C, Häring HU, Claussen CD, Fritsche A, Schick F.

J Magn Reson Imaging. 2009 Jun;29(6):1340-5.PMID: 19422021 [PubMed - indexed for MEDLINE]Related articles

Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion.

Müssig K, Staiger H, Machicao F, Kirchhoff K, Guthoff M, Schäfer SA, Kantartzis K, Silbernagel G, Stefan N, Holst JJ, Gallwitz B, Häring HU, Fritsche A.

Diabetes. 2009 Jul;58(7):1715-20. Epub 2009 Apr 14.PMID: 19366866 [PubMed - indexed for MEDLINE]Related articlesFree article

AHSG gene variation is not associated with regional body fat distribution--a magnetic resonance study.

Müssig K, Staiger H, Machicao F, Machann J, Hennige AM, Schick F, Claussen CD, Fritsche A, Häring HU, Stefan N.

Exp Clin Endocrinol Diabetes. 2009 Sep;117(8):432-7. Epub 2009 Apr 8.PMID: 19358088 [PubMed - in process]Related articles

A common genetic variant in WFS1 determines impaired glucagon-like peptide-1-induced insulin secretion.

Schäfer SA, Müssig K, Staiger H, Machicao F, Stefan N, Gallwitz B, Häring HU, Fritsche A.

Diabetologia. 2009 Jun;52(6):1075-82. Epub 2009 Mar 28.PMID: 19330314 [PubMed - indexed for MEDLINE]Related articles

RARRES2, encoding the novel adipokine chemerin, is a genetic determinant of disproportionate regional body fat distribution: a comparative magnetic resonance imaging study.

Müssig K, Staiger H, Machicao F, Thamer C, Machann J, Schick F, Claussen CD, Stefan N, Fritsche A, Häring HU.

Metabolism. 2009 Apr;58(4):519-24.PMID: 19303973 [PubMed - indexed for MEDLINE]Related articles

The inhibitory effect of recent type 2 diabetes risk loci on insulin secretion is modulated by insulin sensitivity.

Haupt A, Guthoff M, Schäfer SA, Kirchhoff K, Machicao F, Gallwitz B, Staiger H, Stefan N, Fritsche A, Häring HU.

J Clin Endocrinol Metab. 2009 May;94(5):1775-80. Epub 2009 Mar 3.PMID: 19258404 [PubMed - indexed for MEDLINE]Related articles

[A rare cause of hypoglycaemia in a patient with type 2 diabetes]

Heni M, Schott S, Horger M, Dudziak K, Thamer C, Häring HU, Fritsche A, Müssig K.

Dtsch Med Wochenschr. 2009;134 Suppl Falldatenbank:F2. Epub 2009 Feb 23. German. PMID: 19235687 [PubMed - indexed for MEDLINE]Related articles

The risk allele load accelerates the age-dependent decline in beta cell function.

Haupt A, Staiger H, Schäfer SA, Kirchhoff K, Guthoff M, Machicao F, Gallwitz B, Stefan N, Häring HU, Fritsche A.

Diabetologia. 2009 Mar;52(3):457-62. Epub 2009 Jan 27.PMID: 19172244 [PubMed - indexed for MEDLINE]Related articles

Adiponectin oligomers and ectopic fat in liver and skeletal muscle in humans.

Kantartzis K, Staiger H, Machann J, Schick F, Claussen CD, Machicao F, Fritsche A, Häring HU, Stefan N.

Obesity (Silver Spring). 2009 Feb;17(2):390-2. Epub 2008 Oct 30.PMID: 19169222 [PubMed - indexed for MEDLINE]Related articles

Whole-grain consumption and transcription factor-7-like 2 ( TCF7L2) rs7903146: gene-diet interaction in modulating type 2 diabetes risk.

Fisher E, Boeing H, Fritsche A, Doering F, Joost HG, Schulze MB.

Br J Nutr. 2009 Feb;101(4):478-81. Epub 2008 Jul 17.PMID: 19149908 [PubMed - indexed for MEDLINE]Related articles

Psychological effects of prevention: do participants of a type 2 diabetes prevention program experience increased mental distress?

Giel KE, Enck P, Zipfel S, Schrauth M, Bury A, Graf M, Kümmerle S, Guthoff M, Stefan N, Häring HU, Fritsche A.

Diabetes Metab Res Rev. 2009 Jan;25(1):83-8.PMID: 19145589 [PubMed - indexed for MEDLINE]Related articles

Association of common genetic variation in the FOXO1 gene with beta-cell dysfunction, impaired glucose tolerance, and type 2 diabetes.

Müssig K, Staiger H, Machicao F, Stancáková A, Kuusisto J, Laakso M, Thamer C, Machann J, Schick F, Claussen CD, Stefan N, Fritsche A, Häring HU.

J Clin Endocrinol Metab. 2009 Apr;94(4):1353-60. Epub 2009 Jan 13.PMID: 19141580 [PubMed - indexed for MEDLINE]Related articles

Diabetes dietary management alters responses to food pictures in brain regions associated with motivation and emotion: a functional magnetic resonance imaging study.

Chechlacz M, Rotshtein P, Klamer S, Porubská K, Higgs S, Booth D, Fritsche A, Preissl H, Abele H, Birbaumer N, Nouwen A.

Diabetologia. 2009 Mar;52(3):524-33. Epub 2009 Jan 13.PMID: 19139843 [PubMed - indexed for MEDLINE]Related articles

Diagnostic value of melanoma inhibitory activity serum marker in the follow-up of patients with stage I or II cutaneous melanoma.

Hofmann MA, Gussmann F, Fritsche A, Biesold S, Schicke B, Küchler I, Voit C, Trefzer U.

Melanoma Res. 2009 Feb;19(1):17-23.PMID: 19104451 [PubMed - indexed for MEDLINE]Related articles

Polymorphisms within the novel type 2 diabetes risk locus MTNR1B determine beta-cell function.

Staiger H, Machicao F, Schäfer SA, Kirchhoff K, Kantartzis K, Guthoff M, Silbernagel G, Stefan N, Häring HU, Fritsche A.

PLoS One. 2008;3(12):e3962. Epub 2008 Dec 17.PMID: 19088850 [PubMed - indexed for MEDLINE]Related articlesFree article

Muscle-derived angiopoietin-like protein 4 is induced by fatty acids via peroxisome proliferator-activated receptor (PPAR)-delta and is of metabolic relevance in humans.

Staiger H, Haas C, Machann J, Werner R, Weisser M, Schick F, Machicao F, Stefan N, Fritsche A, Häring HU.

Diabetes. 2009 Mar;58(3):579-89. Epub 2008 Dec 15.PMID: 19074989 [PubMed - indexed for MEDLINE]Related articlesFree article

High cardiorespiratory fitness is an independent predictor of the reduction in liver fat during a lifestyle intervention in non-alcoholic fatty liver disease.

Kantartzis K, Thamer C, Peter A, Machann J, Schick F, Schraml C, Königsrainer A, Königsrainer I, Kröber S, Niess A, Fritsche A, Häring HU, Stefan N.

Gut. 2009 Sep;58(9):1281-8. Epub 2008 Dec 11.PMID: 19074179 [PubMed - indexed for MEDLINE]Related articles

Changes of the plasma metabolome during an oral glucose tolerance test: is there more than glucose to look at?

Zhao X, Peter A, Fritsche J, Elcnerova M, Fritsche A, Häring HU, Schleicher ED, Xu G, Lehmann R.

Am J Physiol Endocrinol Metab. 2009 Feb;296(2):E384-93. Epub 2008 Dec 9.PMID: 19066319 [PubMed - indexed for MEDLINE]Related articles

Selective association of plasma non-esterified fatty acid species with circulating interleukin-8 concentrations in humans.

Staiger H, Wöll J, Haas C, Machicao F, Schleicher ED, Fritsche A, Stefan N, Häring HU.

Exp Clin Endocrinol Diabetes. 2009 Jan;117(1):21-7. Epub 2008 Dec 3.PMID: 19053024 [PubMed - indexed for MEDLINE]Related articles

Variation in the FTO gene influences food intake but not energy expenditure.

Haupt A, Thamer C, Staiger H, Tschritter O, Kirchhoff K, Machicao F, Häring HU, Stefan N, Fritsche A.

Exp Clin Endocrinol Diabetes. 2009 Apr;117(4):194-7. Epub 2008 Dec 3.PMID: 19053021 [PubMed - indexed for MEDLINE]Related articles

Plasma fetuin-a levels and the risk of myocardial infarction and ischemic stroke.

Weikert C, Stefan N, Schulze MB, Pischon T, Berger K, Joost HG, Häring HU, Boeing H, Fritsche A.

Circulation. 2008 Dec 9;118(24):2555-62. Epub 2008 Nov 24.PMID: 19029462 [PubMed - indexed for MEDLINE]Related articles

Insulin effects on beta and theta activity in the human brain are differentially affected by ageing.

Tschritter O, Hennige AM, Preissl H, Grichisch Y, Kirchhoff K, Kantartzis K, Machicao F, Fritsche A, Häring HU.

Diabetologia. 2009 Jan;52(1):169-71. Epub 2008 Nov 19. No abstract available. PMID: 19018512 [PubMed - indexed for MEDLINE]Related articles

SIRT1 genetic variants associate with the metabolic response of Caucasians to a controlled lifestyle intervention--the TULIP Study.

Weyrich P, Machicao F, Reinhardt J, Machann J, Schick F, Tschritter O, Stefan N, Fritsche A, Häring HU.

BMC Med Genet. 2008 Nov 12;9:100.PMID: 19014491 [PubMed - indexed for MEDLINE]Related articlesFree article

T2* relaxometry in liver, pancreas, and spleen in a healthy cohort of one hundred twenty-nine subjects-correlation with age, gender, and serum ferritin.

Schwenzer NF, Machann J, Haap MM, Martirosian P, Schraml C, Liebig G, Stefan N, Häring HU, Claussen CD, Fritsche A, Schick F.

Invest Radiol. 2008 Dec;43(12):854-60.PMID: 19002057 [PubMed - indexed for MEDLINE]Related articles

Variance of the SGK1 gene is associated with insulin secretion in different European populations: results from the TUEF, EUGENE2, and METSIM studies.

Friedrich B, Weyrich P, Stancáková A, Wang J, Kuusisto J, Laakso M, Sesti G, Succurro E, Smith U, Hansen T, Pedersen O, Machicao F, Schäfer S, Lang F, Risler T, Ullrich S, Stefan N, Fritsche A, Häring HU.

PLoS One. 2008;3(11):e3506. Epub 2008 Nov 5.PMID: 18985156 [PubMed - indexed for MEDLINE]Related articlesFree article

The DGAT2 gene is a candidate for the dissociation between fatty liver and insulin resistance in humans.

Kantartzis K, Machicao F, Machann J, Schick F, Fritsche A, Häring HU, Stefan N.

Clin Sci (Lond). 2009 Mar;116(6):531-7.PMID: 18980578 [PubMed - indexed for MEDLINE]Related articles

Inverse association of cortisol serum levels with T-tau, P-tau 181 and P-tau 231 peptide levels and T-tau/Abeta 1-42 ratios in CSF in patients with mild Alzheimer's disease dementia.

Laske C, Stransky E, Fritsche A, Eschweiler GW, Leyhe T.

Eur Arch Psychiatry Clin Neurosci. 2009 Mar;259(2):80-5. Epub 2008 Sep 19.PMID: 18806919 [PubMed - indexed for MEDLINE]Related articles

Variation in the CDKAL1 gene is associated with the titer of antibodies to GAD.

Haupt A, Guthoff M, Gallwitz B, Haring HU, Fritsche A.

Diabetes Care. 2008 Sep;31(9):e66. No abstract available. PMID: 18753662 [PubMed - indexed for MEDLINE]Related articlesFree article

The L162V polymorphism of the peroxisome proliferator activated receptor alpha gene (PPARA) is not associated with type 2 diabetes, BMI or body fat composition.

Silbernagel G, Stefan N, Hoffmann MM, Machicao-Arano F, Machann J, Schick F, Winkelmann BR, Boehm BO, Häring HU, Fritsche A, März W.

Exp Clin Endocrinol Diabetes. 2009 Mar;117(3):113-8. Epub 2008 Aug 25.PMID: 18726867 [PubMed - indexed for MEDLINE]Related articles