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    Results: 22

    1.

    Effects of genetic variation in the aldosterone synthase (CYP11B2) gene on enzyme function.

    Holloway CD, MacKenzie SM, Fraser R, Miller S, Barr M, Wilkinson D, Forbes GH, Friel E, Connell JM, Davies E.

    Clin Endocrinol (Oxf). 2009 Mar;70(3):363-71. Epub 2008 Aug 15.PMID: 18710464 [PubMed - indexed for MEDLINE]Related articles

    2.

    Phenotypic consequences of variation across the aldosterone synthase and 11-beta hydroxylase locus in a hypertensive cohort: data from the MRC BRIGHT Study.

    Freel EM, Ingram M, Friel EC, Fraser R, Brown M, Samani NJ, Caulfield M, Munroe P, Farrall M, Webster J, Clayton D, Dominiczak AF, Davies E, Connell JM.

    Clin Endocrinol (Oxf). 2007 Dec;67(6):832-8. Epub 2007 Jul 25.PMID: 17651452 [PubMed - in process]Related articles

    3.

    In vitro and in vivo release of aroma compounds from yellow-fleshed kiwifruit.

    Friel EN, Wang M, Taylor AJ, Macrae EA.

    J Agric Food Chem. 2007 Aug 8;55(16):6664-73. Epub 2007 Jul 7.PMID: 17616207 [PubMed - indexed for MEDLINE]Related articles

    4.

    A genomics approach reveals that aroma production in apple is controlled by ethylene predominantly at the final step in each biosynthetic pathway.

    Schaffer RJ, Friel EN, Souleyre EJ, Bolitho K, Thodey K, Ledger S, Bowen JH, Ma JH, Nain B, Cohen D, Gleave AP, Crowhurst RN, Janssen BJ, Yao JL, Newcomb RD.

    Plant Physiol. 2007 Aug;144(4):1899-912. Epub 2007 Jun 7.PMID: 17556515 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Unusual features of a recombinant apple alpha-farnesene synthase.

    Green S, Friel EN, Matich A, Beuning LL, Cooney JM, Rowan DD, MacRae E.

    Phytochemistry. 2007 Jan;68(2):176-88. Epub 2006 Nov 30.PMID: 17140613 [PubMed - indexed for MEDLINE]Related articles

    6.

    Functional effects of genetic variants in the 11beta-hydroxylase (CYP11B1) gene.

    Barr M, MacKenzie SM, Wilkinson DM, Holloway CD, Friel EC, Miller S, MacDonald T, Fraser R, Connell JM, Davies E.

    Clin Endocrinol (Oxf). 2006 Dec;65(6):816-25.PMID: 17121536 [PubMed - indexed for MEDLINE]Related articles

    7.

    Polymorphic variation in the 11beta-hydroxylase gene associates with reduced 11-hydroxylase efficiency.

    Barr M, MacKenzie SM, Friel EC, Holloway CD, Wilkinson DM, Brain NJ, Ingram MC, Fraser R, Brown M, Samani NJ, Caulfield M, Munroe PB, Farrall M, Webster J, Clayton D, Dominiczak AF, Connell JM, Davies E.

    Hypertension. 2007 Jan;49(1):113-9. Epub 2006 Oct 30.PMID: 17075029 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Transient expression vectors for functional genomics, quantification of promoter activity and RNA silencing in plants.

    Hellens RP, Allan AC, Friel EN, Bolitho K, Grafton K, Templeton MD, Karunairetnam S, Gleave AP, Laing WA.

    Plant Methods. 2005 Dec 18;1:13.PMID: 16359558 [PubMed]Related articlesFree article

    9.

    An alcohol acyl transferase from apple (cv. Royal Gala), MpAAT1, produces esters involved in apple fruit flavor.

    Souleyre EJ, Greenwood DR, Friel EN, Karunairetnam S, Newcomb RD.

    FEBS J. 2005 Jun;272(12):3132-44.PMID: 15955071 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Studies on the origin of circulating 18-hydroxycortisol and 18-oxocortisol in normal human subjects.

    Freel EM, Shakerdi LA, Friel EC, Wallace AM, Davies E, Fraser R, Connell JM.

    J Clin Endocrinol Metab. 2004 Sep;89(9):4628-33.PMID: 15356073 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Aldosterone synthase gene variation and adrenocortical response to sodium status, angiotensin II and ACTH in normal male subjects.

    Kennon B, Ingram MC, Friel EC, Anderson NH, MacKenzie SM, Davies E, Shakerdi L, Wallace AM, Fraser R, Connell JM.

    Clin Endocrinol (Oxf). 2004 Aug;61(2):174-81.PMID: 15272911 [PubMed - indexed for MEDLINE]Related articles

    12.

    The impact of polymorphisms in the gene encoding aldosterone synthase (CYP11B2) on steroid synthesis and blood pressure regulation.

    Connell JM, Fraser R, MacKenzie SM, Friel EC, Ingram MC, Holloway CD, Davies E.

    Mol Cell Endocrinol. 2004 Mar 31;217(1-2):243-7. Review.PMID: 15134824 [PubMed - indexed for MEDLINE]Related articles

    13.

    Variation at the aldosterone synthase (CYP11B2) locus contributes to hypertension in subjects with a raised aldosterone-to-renin ratio.

    Lim PO, Macdonald TM, Holloway C, Friel E, Anderson NH, Dow E, Jung RT, Davies E, Fraser R, Connell JM.

    J Clin Endocrinol Metab. 2002 Sep;87(9):4398-402.PMID: 12213905 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Effects of 18-hydroxylated steroids on corticosteroid production by human aldosterone synthase and 11beta-hydroxylase.

    Fisher A, Friel EC, Bernhardt R, Gomez-Sanchez C, Connell JM, Fraser R, Davies E.

    J Clin Endocrinol Metab. 2001 Sep;86(9):4326-9.PMID: 11549669 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Effect of salivary components on volatile partitioning from solutions.

    Friel EN, Taylor AJ.

    J Agric Food Chem. 2001 Aug;49(8):3898-905.PMID: 11513686 [PubMed - indexed for MEDLINE]Related articles

    16.

    An influence of variation in the aldosterone synthase gene (CYP11B2) on corticosteroid responses to ACTH in normal human subjects.

    Davies E, Holloway CD, Ingram MC, Friel EC, Inglis GC, Swan L, Hillis WS, Fraser R, Connell JM.

    Clin Endocrinol (Oxf). 2001 Jun;54(6):813-7.PMID: 11422117 [PubMed - indexed for MEDLINE]Related articles

    17.

    Polymorphic differences from normal in the aldosterone synthase gene (CYP11B2) in patients with primary hyperaldosteronism and adrenal tumour (Conn's syndrome).

    Inglis GC, Plouin PF, Friel EC, Davies E, Fraser R, Connell JM.

    Clin Endocrinol (Oxf). 2001 Jun;54(6):725-30.PMID: 11422106 [PubMed - indexed for MEDLINE]Related articles

    18.

    Effects of glucose and amino acids on free ADP in betaHC9 insulin-secreting cells.

    Ronner P, Naumann CM, Friel E.

    Diabetes. 2001 Feb;50(2):291-300.PMID: 11272139 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    alpha-adducin and angiotensin I-converting enzyme polymorphisms in essential hypertension.

    Clark CJ, Davies E, Anderson NH, Farmer R, Friel EC, Fraser R, Connell JM.

    Hypertension. 2000 Dec;36(6):990-4.PMID: 11116113 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Luminometric assays of ATP, phosphocreatine, and creatine for estimation of free ADP and free AMP.

    Ronner P, Friel E, Czerniawski K, Fränkle S.

    Anal Biochem. 1999 Nov 15;275(2):208-16.PMID: 10552906 [PubMed - indexed for MEDLINE]Related articles

    21.

    Aldosterone excretion rate and blood pressure in essential hypertension are related to polymorphic differences in the aldosterone synthase gene CYP11B2.

    Davies E, Holloway CD, Ingram MC, Inglis GC, Friel EC, Morrison C, Anderson NH, Fraser R, Connell JM.

    Hypertension. 1999 Feb;33(2):703-7.PMID: 10024332 [PubMed - indexed for MEDLINE]Related articlesFree article

    22.

    Adjuvant vigabatrin in refractory epilepsy: a ceiling to effective dosage in individual patients?

    McKee PJ, Blacklaw J, Friel E, Thompson GG, Gillham RA, Brodie MJ.

    Epilepsia. 1993 Sep-Oct;34(5):937-43.PMID: 8404750 [PubMed - indexed for MEDLINE]Related articles

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