PubMed

Acanthosis nigricans: a practical approach to evaluation and management.

Higgins SP, Freemark M, Prose NS.

Dermatol Online J. 2008 Sep 15;14(9):2. Review.PMID: 19061584 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevention and treatment of pediatric obesity: an endocrine society clinical practice guideline based on expert opinion.

August GP, Caprio S, Fennoy I, Freemark M, Kaufman FR, Lustig RH, Silverstein JH, Speiser PW, Styne DM, Montori VM; Endocrine Society.

J Clin Endocrinol Metab. 2008 Dec;93(12):4576-99. Epub 2008 Sep 9. Review.PMID: 18782869 [PubMed - indexed for MEDLINE]Related articles

Ghrelin concentrations in Prader-Willi syndrome (PWS) infants and children: changes during development.

Haqq AM, Grambow SC, Muehlbauer M, Newgard CB, Svetkey LP, Carrel AL, Yanovski JA, Purnell JQ, Freemark M.

Clin Endocrinol (Oxf). 2008 Dec;69(6):911-20. Epub 2008 Aug 15.PMID: 18710462 [PubMed - indexed for MEDLINE]Related articlesFree article

The interplay of prolactin and the glucocorticoids in the regulation of beta-cell gene expression, fatty acid oxidation, and glucose-stimulated insulin secretion: implications for carbohydrate metabolism in pregnancy.

Arumugam R, Horowitz E, Lu D, Collier JJ, Ronnebaum S, Fleenor D, Freemark M.

Endocrinology. 2008 Nov;149(11):5401-14. Epub 2008 Jul 3.PMID: 18599550 [PubMed - indexed for MEDLINE]Related articlesFree article

Seropositivity to celiac antigens in asymptomatic children with type 1 diabetes mellitus: association with weight, height, and bone mineralization.

Artz E, Warren-Ulanch J, Becker D, Greenspan S, Freemark M.

Pediatr Diabetes. 2008 Jul 28;9(4 Pt 1):277-84. Epub 2008 May 7.PMID: 18466211 [PubMed - indexed for MEDLINE]Related articles

Prolactin receptor signaling is essential for perinatal brown adipocyte function: a role for insulin-like growth factor-2.

Viengchareun S, Servel N, Fève B, Freemark M, Lombès M, Binart N.

PLoS One. 2008 Feb 6;3(2):e1535.PMID: 18253483 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of lactogen resistance and GH deficiency on mouse metabolism: pancreatic hormones, adipocytokines, and expression of adiponectin and insulin receptors.

Arumugam R, Fleenor D, Freemark M.

Endocrine. 2007 Oct;32(2):182-91. Epub 2007 Nov 2.PMID: 17975745 [PubMed - indexed for MEDLINE]Related articles

Liver dysfunction in paediatric obesity: a randomized, controlled trial of metformin.

Freemark M.

Acta Paediatr. 2007 Sep;96(9):1326-32.PMID: 17718786 [PubMed - indexed for MEDLINE]Related articles

Altered distribution of adiponectin isoforms in children with Prader-Willi syndrome (PWS): association with insulin sensitivity and circulating satiety peptide hormones.

Haqq AM, Muehlbauer M, Svetkey LP, Newgard CB, Purnell JQ, Grambow SC, Freemark MS.

Clin Endocrinol (Oxf). 2007 Dec;67(6):944-51. Epub 2007 Jul 30.PMID: 17666087 [PubMed - in process]Related articlesFree article

Pharmacotherapy of childhood obesity: an evidence-based, conceptual approach.

Freemark M.

Diabetes Care. 2007 Feb;30(2):395-402. Review. No abstract available. PMID: 17259519 [PubMed - indexed for MEDLINE]Related articlesFree article

Lactogenic and somatogenic hormones regulate the expression of neuropeptide Y and cocaine- and amphetamine-regulated transcript in rat insulinoma (INS-1) cells: interactions with glucose and glucocorticoids.

Arumugam R, Fleenor D, Freemark M.

Endocrinology. 2007 Jan;148(1):258-67. Epub 2006 Oct 5.PMID: 17023531 [PubMed - indexed for MEDLINE]Related articlesFree article

Growth hormone and prolactin receptors in adipogenesis: STAT-5 activation, suppressors of cytokine signaling, and regulation of insulin-like growth factor I.

Fleenor D, Arumugam R, Freemark M.

Horm Res. 2006;66(3):101-10. Epub 2006 May 30.PMID: 16735796 [PubMed - indexed for MEDLINE]Related articles

Regulation of maternal metabolism by pituitary and placental hormones: roles in fetal development and metabolic programming.

Freemark M.

Horm Res. 2006;65 Suppl 3:41-9. Epub 2006 Apr 10. Review.PMID: 16612113 [PubMed - indexed for MEDLINE]Related articles

Anti-obesity medication use in adolescents: risks and benefits.

Freemark M, Kiess W.

Pediatr Endocrinol Rev. 2004 Nov;2 Suppl 1:168-70. Review.PMID: 16456496 [PubMed - indexed for MEDLINE]Related articles

The pathogenesis of insulin resistance in children: metabolic complications and the roles of diet, exercise and pharmacotherapy in the prevention of type 2 diabetes.

Artz E, Freemark M.

Pediatr Endocrinol Rev. 2004 Mar;1(3):296-309. Review.PMID: 16437023 [PubMed - indexed for MEDLINE]Related articles

Hormonal and metabolic consequences of childhood obesity.

Artz E, Haqq A, Freemark M.

Endocrinol Metab Clin North Am. 2005 Sep;34(3):643-58, ix. Review.PMID: 16085164 [PubMed - indexed for MEDLINE]Related articles

Childhood obesity.

Speiser PW, Rudolf MC, Anhalt H, Camacho-Hubner C, Chiarelli F, Eliakim A, Freemark M, Gruters A, Hershkovitz E, Iughetti L, Krude H, Latzer Y, Lustig RH, Pescovitz OH, Pinhas-Hamiel O, Rogol AD, Shalitin S, Sultan C, Stein D, Vardi P, Werther GA, Zadik Z, Zuckerman-Levin N, Hochberg Z; Obesity Consensus Working Group.

J Clin Endocrinol Metab. 2005 Mar;90(3):1871-87. Epub 2004 Dec 14. Review.PMID: 15598688 [PubMed - indexed for MEDLINE]Related articlesFree article

Roles of the lactogens and somatogens in perinatal and postnatal metabolism and growth: studies of a novel mouse model combining lactogen resistance and growth hormone deficiency.

Fleenor D, Oden J, Kelly PA, Mohan S, Alliouachene S, Pende M, Wentz S, Kerr J, Freemark M.

Endocrinology. 2005 Jan;146(1):103-12. Epub 2004 Sep 23.PMID: 15388648 [PubMed - indexed for MEDLINE]Related articlesFree article

Editorial: Growth hormone treatment of "idiopathic short stature": not so fast.

Freemark M.

J Clin Endocrinol Metab. 2004 Jul;89(7):3138-9. No abstract available. PMID: 15240583 [PubMed - indexed for MEDLINE]Related articlesFree article

Screening for celiac disease in children with type 1 diabetes: two views of the controversy.

Freemark M, Levitsky LL.

Diabetes Care. 2003 Jun;26(6):1932-9. Review. No abstract available. PMID: 12766138 [PubMed - indexed for MEDLINE]Related articlesFree article

Pharmacologic approaches to the prevention of type 2 diabetes in high risk pediatric patients.

Freemark M.

J Clin Endocrinol Metab. 2003 Jan;88(1):3-13. Review. No abstract available. PMID: 12519819 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin pump therapy in toddlers and preschool children with type 1 diabetes mellitus.

Litton J, Rice A, Friedman N, Oden J, Lee MM, Freemark M.

J Pediatr. 2002 Oct;141(4):490-5.PMID: 12378187 [PubMed - indexed for MEDLINE]Related articles

Leptin in the newborn mouse. Plasma concentrations, characterization of the circulating hormone, and tissue source.

Oden J, Fleenor D, Driscoll P, Freemark M.

Biol Neonate. 2002 Aug;82(2):109-16.PMID: 12169833 [PubMed - indexed for MEDLINE]Related articles

Thyroxine supplementation in preterm infants: critical analysis.

Oden J, Freemark M.

Curr Opin Pediatr. 2002 Aug;14(4):447-52. Review. No abstract available. PMID: 12130911 [PubMed - indexed for MEDLINE]Related articles

Targeted deletion of the PRL receptor: effects on islet development, insulin production, and glucose tolerance.

Freemark M, Avril I, Fleenor D, Driscoll P, Petro A, Opara E, Kendall W, Oden J, Bridges S, Binart N, Breant B, Kelly PA.

Endocrinology. 2002 Apr;143(4):1378-85.PMID: 11897695 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypothyroxinemia in the preterm infant: the benefits and risks of thyroxine treatment.

Rapaport R, Rose SR, Freemark M.

J Pediatr. 2001 Aug;139(2):182-8. Review. No abstract available. PMID: 11487741 [PubMed - indexed for MEDLINE]Related articles

Prolactin induction of insulin gene transcription: roles of glucose and signal transducer and activator of transcription 5.

Fleenor DE, Freemark M.

Endocrinology. 2001 Jul;142(7):2805-10.PMID: 11415999 [PubMed - indexed for MEDLINE]Related articlesFree article

The effects of metformin on body mass index and glucose tolerance in obese adolescents with fasting hyperinsulinemia and a family history of type 2 diabetes.

Freemark M, Bursey D.

Pediatrics. 2001 Apr;107(4):E55.PMID: 11335776 [PubMed - indexed for MEDLINE]Related articlesFree article

Prolactin receptor signal transduction pathways and actions determined in prolactin receptor knockout mice.

Kelly PA, Binart N, Freemark M, Lucas B, Goffin V, Bouchard B.

Biochem Soc Trans. 2001 May;29(Pt 2):48-52. Review.PMID: 11356125 [PubMed - indexed for MEDLINE]Related articles

Ontogenesis of prolactin receptors in the human fetus: roles in fetal development.

Freemark M.

Biochem Soc Trans. 2001 May;29(Pt 2):38-41. Review.PMID: 11356123 [PubMed - indexed for MEDLINE]Related articles

Body weight and fat deposition in prolactin receptor-deficient mice.

Freemark M, Fleenor D, Driscoll P, Binart N, Kelly P.

Endocrinology. 2001 Feb;142(2):532-7.PMID: 11159821 [PubMed - indexed for MEDLINE]Related articlesFree article

The roles of placental growth hormone and placental lactogen in the regulation of human fetal growth and development.

Handwerger S, Freemark M.

J Pediatr Endocrinol Metab. 2000 Apr;13(4):343-56. Review.PMID: 10776988 [PubMed - indexed for MEDLINE]Related articles

Prolactin induction of insulin gene expression: the roles of glucose and glucose transporter-2.

Petryk A, Fleenor D, Driscoll P, Freemark M.

J Endocrinol. 2000 Mar;164(3):277-86.PMID: 10694367 [PubMed - indexed for MEDLINE]Related articlesFree article

Constitutive expression of placental lactogen in pancreatic beta cells: effects on cell morphology, growth, and gene expression.

Fleenor D, Petryk A, Driscoll P, Freemark M.

Pediatr Res. 2000 Jan;47(1):136-42.PMID: 10625094 [PubMed - indexed for MEDLINE]Related articles

The fetal adrenal and the maturation of the growth hormone and prolactin axes.

Freemark M.

Endocrinology. 1999 May;140(5):1963-5. Review. No abstract available. PMID: 10218942 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical review 99: The management of Graves' disease in children, with special emphasis on radioiodine treatment.

Rivkees SA, Sklar C, Freemark M.

J Clin Endocrinol Metab. 1998 Nov;83(11):3767-76. Review. No abstract available. PMID: 9814445 [PubMed - indexed for MEDLINE]Related articlesFree article

Ontogenesis of prolactin receptors in the human fetus in early gestation. Implications for tissue differentiation and development.

Freemark M, Driscoll P, Maaskant R, Petryk A, Kelly PA.

J Clin Invest. 1997 Mar 1;99(5):1107-17.PMID: 9062370 [PubMed - indexed for MEDLINE]Related articlesFree article

Ontogenesis of prolactin receptor gene expression in the rat olfactory system: potential roles for lactogenic hormones in olfactory development.

Freemark M, Driscoll P, Andrews J, Kelly PA, Royster M.

Endocrinology. 1996 Mar;137(3):934-42.PMID: 8603606 [PubMed - indexed for MEDLINE]Related articles

The prolactin receptor in the fetal rat: cellular localization of messenger ribonucleic acid, immunoreactive protein, and ligand-binding activity and induction of expression in late gestation.

Royster M, Driscoll P, Kelly PA, Freemark M.

Endocrinology. 1995 Sep;136(9):3892-900.PMID: 7649097 [PubMed - indexed for MEDLINE]Related articles

Human placental lactogen infusions into the medial preoptic area stimulate maternal behavior in steroid-primed, nulliparous female rats.

Bridges RS, Freemark MS.

Horm Behav. 1995 Jun;29(2):216-26.PMID: 7557924 [PubMed - indexed for MEDLINE]Related articles

Prolactin receptor gene expression in the fetal rat.

Freemark M, Nagano M, Edery M, Kelly PA.

J Endocrinol. 1995 Feb;144(2):285-92.PMID: 7706981 [PubMed - indexed for MEDLINE]Related articles

Rat placental lactogen-I binds to the choroid plexus and hypothalamus of the pregnant rat.

Pihoker C, Robertson MC, Freemark M.

J Endocrinol. 1993 Nov;139(2):235-42.PMID: 8308459 [PubMed - indexed for MEDLINE]Related articles

Pregnancy lactogens in the rat conceptus and fetus: circulating levels, distribution of binding, and expression of receptor messenger ribonucleic acid.

Freemark M, Kirk K, Pihoker C, Robertson MC, Shiu RP, Driscoll P.

Endocrinology. 1993 Oct;133(4):1830-42.PMID: 8404626 [PubMed - indexed for MEDLINE]Related articles

Placental lactogen-binding sites in isolated fetal fibroblasts: characterization, processing, and regulation.

Fowlkes J, Freemark M.

Endocrinology. 1993 Jun;132(6):2477-83.PMID: 8389282 [PubMed - indexed for MEDLINE]Related articles

Evidence for a novel insulin-like growth factor (IGF)-dependent protease regulating IGF-binding protein-4 in dermal fibroblasts.

Fowlkes J, Freemark M.

Endocrinology. 1992 Nov;131(5):2071-6.PMID: 1385096 [PubMed - indexed for MEDLINE]Related articles

Nutritional regulation of insulin-like growth factor-binding protein gene expression in the ovine fetus and pregnant ewe.

Osborn BH, Fowlkes J, Han VK, Freemark M.

Endocrinology. 1992 Oct;131(4):1743-50.PMID: 1382960 [PubMed - indexed for MEDLINE]Related articles

Binding of placental lactogen and growth hormone to fetal sheep fibroblasts.

Fowlkes J, Freemark M.

Pediatr Res. 1992 Aug;32(2):200-3.PMID: 1508610 [PubMed - indexed for MEDLINE]Related articles

Developmental regulation of insulin-like growth factor binding protein production: studies in fetal, postnatal, and pregnant sheep.

Fowlkes J, Freemark M.

J Cell Physiol. 1992 Jul;152(1):19-27.PMID: 1377698 [PubMed - indexed for MEDLINE]Related articles

The placental lactogen receptor in maternal and fetal sheep liver: regulation by glucose and role in the pathogenesis of fasting during pregnancy.

Freemark M, Keen A, Fowlkes J, Mularoni T, Comer M, Grandis A, Kodack L.

Endocrinology. 1992 Feb;130(2):1063-70.PMID: 1310275 [PubMed - indexed for MEDLINE]Related articles

Placental lactogen receptors in maternal sheep liver: effects of fasting and refeeding.

Freemark M, Comer M, Mularoni T, D'Ercole AJ, Grandis A, Kodack L.

Am J Physiol. 1990 Feb;258(2 Pt 1):E338-46.PMID: 2154937 [PubMed - indexed for MEDLINE]Related articles