PubMed

A protein caught in a kinetic trap: structures and stabilities of insulin disulfide isomers.

Hua QX, Jia W, Frank BH, Phillips NF, Weiss MA.

Biochemistry. 2002 Dec 17;41(50):14700-15.PMID: 12475219 [PubMed - indexed for MEDLINE]Related articles

Stability of U-10 and U-50 dilutions of insulin lispro.

Stickelmeyer MP, Graf CJ, Frank BH, Ballard RL, Storms SM.

Diabetes Technol Ther. 2000 Spring;2(1):61-6.PMID: 11467323 [PubMed - indexed for MEDLINE]Related articles

Insulin self-association and the relationship to pharmacokinetics and pharmacodynamics.

DeFelippis MR, Chance RE, Frank BH.

Crit Rev Ther Drug Carrier Syst. 2001;18(2):201-64. Review.PMID: 11325032 [PubMed - indexed for MEDLINE]Related articles

Structural studies of a crystalline insulin analog complex with protamine by atomic force microscopy.

Yip CM, Brader ML, Frank BH, DeFelippis MR, Ward MD.

Biophys J. 2000 Jan;78(1):466-73.PMID: 10620310 [PubMed - indexed for MEDLINE]Related articlesFree article

Preparation of a microcrystalline suspension formulation of Lys(B28)Pro(B29)-human insulin with ultralente properties.

Richards JP, Stickelmeyer MP, Frank BH, Pye S, Barbeau M, Radziuk J, Smith GD, DeFelippis MR.

J Pharm Sci. 1999 Sep;88(9):861-7.PMID: 10479347 [PubMed - indexed for MEDLINE]Related articles

A novel protein cross-linking reaction in stressed neutral protein hagdedorn formulations of insulin

Beavis R, Knierman MD, Sharknas D, Heady MA, Frank BH, DeFelippis MR.

J Pharm Sci. 1999 Aug;88(8):842. No abstract available. PMID: 10430552 [PubMed - as supplied by publisher]Related articles

Differences in the cellular processing of AspB10 human insulin compared with human insulin and LysB28ProB29 human insulin.

Hamel FG, Siford GL, Fawcett J, Chance RE, Frank BH, Duckworth WC.

Metabolism. 1999 May;48(5):611-7.PMID: 10337862 [PubMed - indexed for MEDLINE]Related articles

A novel protein cross-linking reaction in stressed Neutral Protamine Hagedorn formulations of insulin.

Beavis RC, Kneirman MD, Sharknas D, Heady MA, Frank BH, DeFelippis MR.

J Pharm Sci. 1999 Mar;88(3):331-6.PMID: 10052992 [PubMed - indexed for MEDLINE]Related articles

The development of recombinant human insulin.

Frank BH.

Dev Biol Stand. 1998;96:91-5. No abstract available. PMID: 9890521 [PubMed - indexed for MEDLINE]Related articles

Physical stress testing of insulin suspensions and solutions.

Shnek DR, Hostettler DL, Bell MA, Olinger JM, Frank BH.

J Pharm Sci. 1998 Nov;87(11):1459-65.PMID: 9811506 [PubMed - indexed for MEDLINE]Related articles

Self-association properties of monomeric insulin analogs under formulation conditions.

Richards JP, Stickelmeyer MP, Flora DB, Chance RE, Frank BH, DeFelippis MR.

Pharm Res. 1998 Sep;15(9):1434-41.PMID: 9755897 [PubMed - indexed for MEDLINE]Related articles

Structural and morphological characterization of ultralente insulin crystals by atomic force microscopy: evidence of hydrophobically driven assembly.

Yip CM, DeFelippis MR, Frank BH, Brader ML, Ward MD.

Biophys J. 1998 Sep;75(3):1172-9.PMID: 9726919 [PubMed - indexed for MEDLINE]Related articlesFree article

First direct assay for intact human proinsulin.

Houssa P, Dinesen B, Deberg M, Frank BH, Van Schravendijk C, Sodoyez-Goffaux F, Sodoyez JC.

Clin Chem. 1998 Jul;44(7):1514-9.PMID: 9665431 [PubMed - indexed for MEDLINE]Related articlesFree article

Highly specific radioimmunoassay for human insulin based on immune exclusion of all insulin precursors.

Deberg M, Houssa P, Frank BH, Sodoyez-Goffaux F, Sodoyez JC.

Clin Chem. 1998 Jul;44(7):1504-13.PMID: 9665430 [PubMed - indexed for MEDLINE]Related articlesFree article

Preparation and characterization of a cocrystalline suspension of [LysB28,ProB29]-human insulin analogue.

DeFelippis MR, Bakaysa DL, Bell MA, Heady MA, Li S, Pye S, Youngman KM, Radziuk J, Frank BH.

J Pharm Sci. 1998 Feb;87(2):170-6.PMID: 9519149 [PubMed - indexed for MEDLINE]Related articles

Taxes. Contract hits.

Frank BH.

Health Syst Rev. 1997 Nov-Dec;30(6):19-21. No abstract available. PMID: 10175034 [PubMed - indexed for MEDLINE]Related articles

Stability of insulin lispro in insulin infusion systems.

Lougheed WD, Zinman B, Strack TR, Janis LJ, Weymouth AB, Bernstein EA, Korbas AM, Frank BH.

Diabetes Care. 1997 Jul;20(7):1061-5.PMID: 9203437 [PubMed - indexed for MEDLINE]Related articles

Hospital-based physicians--independent contractor or ?

Frank BH.

Cost Qual Q J. 1997 Jan;3(1):6-12.PMID: 10167588 [PubMed - indexed for MEDLINE]Related articles

Mapping the functional surface of insulin by design: structure and function of a novel A-chain analogue.

Hua QX, Hu SQ, Frank BH, Jia W, Chu YC, Wang SH, Burke GT, Katsoyannis PG, Weiss MA.

J Mol Biol. 1996 Nov 29;264(2):390-403.PMID: 8951384 [PubMed - indexed for MEDLINE]Related articles

Structure and dynamics of a protein assembly. 1H-NMR studies of the 36 kDa R6 insulin hexamer.

Jacoby E, Hua QX, Stern AS, Frank BH, Weiss MA.

J Mol Biol. 1996 Apr 26;258(1):136-57.PMID: 8613983 [PubMed - indexed for MEDLINE]Related articles

Role of C-terminal B-chain residues in insulin assembly: the structure of hexameric LysB28ProB29-human insulin.

Ciszak E, Beals JM, Frank BH, Baker JC, Carter ND, Smith GD.

Structure. 1995 Jun 15;3(6):615-22.PMID: 8590022 [PubMed - indexed for MEDLINE]Related articles

Structure of a protein in a kinetic trap.

Hua QX, Gozani SN, Chance RE, Hoffmann JA, Frank BH, Weiss MA.

Nat Struct Biol. 1995 Feb;2(2):129-38.PMID: 7749917 [PubMed - indexed for MEDLINE]Related articles

Research, development, production, and safety of biosynthetic human insulin.

Chance RE, Frank BH.

Diabetes Care. 1993 Dec;16 Suppl 3:133-42. Review.PMID: 8299470 [PubMed - indexed for MEDLINE]Related articles

Comparison of the dynamics of an engineered insulin monomer and dimer by acid-quenched amide proton exchange. Non-local stabilization of interchain hydrogen bonds by dimerization.

Hua QX, Jia W, Frank BH, Weiss MA.

J Mol Biol. 1993 Mar 20;230(2):387-94.PMID: 8464054 [PubMed - indexed for MEDLINE]Related articles

A rapid and sensitive radioimmunoassay for the measurement of proinsulin in human serum.

Bowsher RR, Wolny JD, Frank BH.

Diabetes. 1992 Sep;41(9):1084-90.PMID: 1499862 [PubMed - indexed for MEDLINE]Related articles

Altering the association properties of insulin by amino acid replacement.

Brems DN, Alter LA, Beckage MJ, Chance RE, DiMarchi RD, Green LK, Long HB, Pekar AH, Shields JE, Frank BH.

Protein Eng. 1992 Sep;5(6):527-33.PMID: 1438163 [PubMed - indexed for MEDLINE]Related articles

Improved insulin stability through amino acid substitution.

Brems DN, Brown PL, Bryant C, Chance RE, Green LK, Long HB, Miller AA, Millican R, Shields JE, Frank BH.

Protein Eng. 1992 Sep;5(6):519-25.PMID: 1438162 [PubMed - indexed for MEDLINE]Related articles

Biosynthetic human proinsulin. Review of chemistry, in vitro and in vivo receptor binding, animal and human pharmacology studies, and clinical trial experience.

Galloway JA, Hooper SA, Spradlin CT, Howey DC, Frank BH, Bowsher RR, Anderson JH.

Diabetes Care. 1992 May;15(5):666-92. Review.PMID: 1516487 [PubMed - indexed for MEDLINE]Related articles

Heteronuclear 2D NMR studies of an engineered insulin monomer: assignment and characterization of the receptor-binding surface by selective 2H and 13C labeling with application to protein design.

Weiss MA, Hua QX, Lynch CS, Frank BH, Shoelson SE.

Biochemistry. 1991 Jul 30;30(30):7373-89.PMID: 1906742 [PubMed - indexed for MEDLINE]Related articles

The interaction of proinsulin with the insulin-like growth factor-I receptor in human liver, muscle, and adipose tissue.

Burguera B, Frank BH, DiMarchi R, Long S, Caro JF.

J Clin Endocrinol Metab. 1991 Jun;72(6):1238-41.PMID: 1851182 [PubMed - indexed for MEDLINE]Related articles

Effect of bacitracin on retroendocytosis and degradation of insulin in cultured kidney epithelial cell line.

Dahl DC, Tsao T, Duckworth WC, Frank BH, Rabkin R.

Diabetes. 1990 Nov;39(11):1339-46.PMID: 2227108 [PubMed - indexed for MEDLINE]Related articles

Hypoglycemic potency and metabolic clearance rate of intravenously administered human proinsulin and metabolites.

Tillil H, Frank BH, Pekar AH, Broelsch C, Rubenstein AH, Polonsky KS.

Endocrinology. 1990 Nov;127(5):2418-22.PMID: 2226325 [PubMed - indexed for MEDLINE]Related articles

Equilibrium denaturation of insulin and proinsulin.

Brems DN, Brown PL, Heckenlaible LA, Frank BH.

Biochemistry. 1990 Oct 2;29(39):9289-93.PMID: 2271596 [PubMed - indexed for MEDLINE]Related articles

NMR and photo-CIDNP studies of human proinsulin and prohormone processing intermediates with application to endopeptidase recognition.

Weiss MA, Frank BH, Khait I, Pekar A, Heiney R, Shoelson SE, Neuringer LJ.

Biochemistry. 1990 Sep 11;29(36):8389-401.PMID: 2252901 [PubMed - indexed for MEDLINE]Related articles

Agency nurse vs. IRS: are you an employee, an independent contractor, or both?

Sumner SM, Grau PA, Frank BH.

Am J Nurs. 1990 Mar;90(3):25-6. No abstract available. PMID: 2309803 [PubMed - indexed for MEDLINE]Related articles

Two-dimensional NMR and photo-CIDNP studies of the insulin monomer: assignment of aromatic resonances with application to protein folding, structure, and dynamics.

Weiss MA, Nguyen DT, Khait I, Inouye K, Frank BH, Beckage M, O'Shea E, Shoelson SE, Karplus M, Neuringer LJ.

Biochemistry. 1989 Dec 12;28(25):9855-73.PMID: 2692717 [PubMed - indexed for MEDLINE]Related articles

Sensitive and specific two-site immunoradiometric assays for human insulin, proinsulin, 65-66 split and 32-33 split proinsulins.

Sobey WJ, Beer SF, Carrington CA, Clark PM, Frank BH, Gray IP, Luzio SD, Owens DR, Schneider AE, Siddle K, et al.

Biochem J. 1989 Jun 1;260(2):535-41.PMID: 2669734 [PubMed - indexed for MEDLINE]Related articlesFree article

Drosophila insulin degrading enzyme and rat skeletal muscle insulin protease cleave insulin at similar sites.

Duckworth WC, Garcia JV, Liepnieks JJ, Hamel FG, Hermodson MA, Frank BH, Rosner MR.

Biochemistry. 1989 Mar 21;28(6):2471-7.PMID: 2659071 [PubMed - indexed for MEDLINE]Related articles

High performance liquid chromatographic analysis of insulin degradation products from a cultured kidney cell line.

Duckworth WC, Hamel FG, Liepnieks J, Frank BH, Yagil C, Rabkin R.

Endocrinology. 1988 Dec;123(6):2701-8.PMID: 3058457 [PubMed - indexed for MEDLINE]Related articles

Scintigraphic distribution of 123 I labelled proinsulin, split conversion intermediates and insulin in rats.

Sodoyez-Goffaux F, Sodoyez JC, Koch M, De Vos CJ, Frank BH.

Diabetologia. 1988 Nov;31(11):848-54.PMID: 3234639 [PubMed - indexed for MEDLINE]Related articles

Conversion of biosynthetic human proinsulin to partially cleaved intermediates by collagenase proteinases adsorbed to isolated rat adipocytes.

Duckworth WC, Peavy DE, Hamel FG, Liepnieks J, Brunner MR, Heiney RE, Frank BH.

Biochem J. 1988 Oct 1;255(1):277-84.PMID: 2848505 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of specific pancreatic polypeptide receptors on basolateral membranes of the canine small intestine.

Gilbert WR, Frank BH, Gavin JR 3rd, Gingerich RL.

Proc Natl Acad Sci U S A. 1988 Jul;85(13):4745-9.PMID: 3387434 [PubMed - indexed for MEDLINE]Related articlesFree article

Binding of proinsulin and proinsulin conversion intermediates to human placental insulin-like growth factor I receptors.

Gruppuso PA, Frank BH, Schwartz R.

J Clin Endocrinol Metab. 1988 Jul;67(1):194-7.PMID: 2967852 [PubMed - indexed for MEDLINE]Related articles

Effect of bacitracin on binding and processing of insulin by established renal cell line.

Yagil C, Frank BH, Rabkin R.

Diabetes. 1988 Jun;37(6):800-5.PMID: 3290001 [PubMed - indexed for MEDLINE]Related articles

Internalization and catabolism of insulin by an established renal cell line.

Yagil C, Frank BH, Rabkin R.

Am J Physiol. 1988 Jun;254(6 Pt 1):C822-8.PMID: 3287948 [PubMed - indexed for MEDLINE]Related articles

Differential binding of monoiodinated insulins to muscle and liver derived receptors and activation of the receptor kinase.

Burant CF, Treutelaar MK, Peavy DE, Frank BH, Buse MG.

Biochem Biophys Res Commun. 1988 May 16;152(3):1353-60.PMID: 2837184 [PubMed - indexed for MEDLINE]Related articles

Isolation of insulin degradation products from endosomes derived from intact rat liver.

Hamel FG, Posner BI, Bergeron JJ, Frank BH, Duckworth WC.

J Biol Chem. 1988 May 15;263(14):6703-8.PMID: 3283131 [PubMed - indexed for MEDLINE]Related articlesFree article

Abnormal patterns of insulin secretion in non-insulin-dependent diabetes mellitus.

Polonsky KS, Given BD, Hirsch LJ, Tillil H, Shapiro ET, Beebe C, Frank BH, Galloway JA, Van Cauter E.

N Engl J Med. 1988 May 12;318(19):1231-9.PMID: 3283554 [PubMed - indexed for MEDLINE]Related articles

Insulin binding, internalization, and degradation by a cultured kidney cell line.

Yagil C, Ehmann UK, Frank BH, Rabkin R.

Am J Physiol. 1988 May;254(5 Pt 1):E601-8.PMID: 2834959 [PubMed - indexed for MEDLINE]Related articles

Differences in renal metabolism of insulin and cytochrome c.

Herrman J, Simmons RE, Frank BH, Rabkin R.

Am J Physiol. 1988 Apr;254(4 Pt 1):E419-28.PMID: 2833109 [PubMed - indexed for MEDLINE]Related articles