PubMed

Serum carboxymethyllysine concentrations are reduced in diabetic men with abdominal aortic aneurysms: Health In Men Study.

Norman PE, Davis WA, Coughlan MT, Forbes JM, Golledge J, Davis TM.

J Vasc Surg. 2009 Sep;50(3):626-31. Epub 2009 Jul 22.PMID: 19628355 [PubMed - indexed for MEDLINE]Related articles

A new perspective on therapeutic inhibition of advanced glycation in diabetic microvascular complications: common downstream endpoints achieved through disparate therapeutic approaches?

Sourris KC, Harcourt BE, Forbes JM.

Am J Nephrol. 2009;30(4):323-35. Epub 2009 Jun 29.PMID: 19556753 [PubMed - in process]Related articles

High-density lipoprotein modulates glucose metabolism in patients with type 2 diabetes mellitus.

Drew BG, Duffy SJ, Formosa MF, Natoli AK, Henstridge DC, Penfold SA, Thomas WG, Mukhamedova N, de Courten B, Forbes JM, Yap FY, Kaye DM, van Hall G, Febbraio MA, Kemp BE, Sviridov D, Steinberg GR, Kingwell BA.

Circulation. 2009 Apr 21;119(15):2103-11. Epub 2009 Apr 6.PMID: 19349317 [PubMed - indexed for MEDLINE]Related articles

c-Jun NH2-terminal kinase activity in subcutaneous adipose tissue but not nuclear factor-kappaB activity in peripheral blood mononuclear cells is an independent determinant of insulin resistance in healthy individuals.

Sourris KC, Lyons JG, de Courten MP, Dougherty SL, Henstridge DC, Cooper ME, Hage M, Dart A, Kingwell BA, Forbes JM, de Courten B.

Diabetes. 2009 Jun;58(6):1259-65. Epub 2009 Mar 3.PMID: 19258436 [PubMed - indexed for MEDLINE]Related articlesFree article

RAGE-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes.

Coughlan MT, Thorburn DR, Penfold SA, Laskowski A, Harcourt BE, Sourris KC, Tan AL, Fukami K, Thallas-Bonke V, Nawroth PP, Brownlee M, Bierhaus A, Cooper ME, Forbes JM.

J Am Soc Nephrol. 2009 Apr;20(4):742-52. Epub 2009 Jan 21.PMID: 19158353 [PubMed - indexed for MEDLINE]Related articles

Interactions between advanced glycation end-products (AGE) and their receptors in the development and progression of diabetic nephropathy - are these receptors valid therapeutic targets.

Sourris KC, Forbes JM.

Curr Drug Targets. 2009 Jan;10(1):42-50. Review.PMID: 19149535 [PubMed - indexed for MEDLINE]Related articles

A personal view of how ruminant animals control their intake and choice of food: minimal total discomfort.

Forbes JM.

Nutr Res Rev. 2007 Dec;20(2):132-46.PMID: 19079866 [PubMed]Related articles

Heat shock protein expression in diabetic nephropathy.

Barutta F, Pinach S, Giunti S, Vittone F, Forbes JM, Chiarle R, Arnstein M, Perin PC, Camussi G, Cooper ME, Gruden G.

Am J Physiol Renal Physiol. 2008 Dec;295(6):F1817-24. Epub 2008 Oct 15.PMID: 18922888 [PubMed - indexed for MEDLINE]Related articles

Receptor for advanced glycation end products (RAGE) deficiency attenuates the development of atherosclerosis in diabetes.

Soro-Paavonen A, Watson AM, Li J, Paavonen K, Koitka A, Calkin AC, Barit D, Coughlan MT, Drew BG, Lancaster GI, Thomas M, Forbes JM, Nawroth PP, Bierhaus A, Cooper ME, Jandeleit-Dahm KA.

Diabetes. 2008 Sep;57(9):2461-9. Epub 2008 May 28.PMID: 18511846 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidative stress as a major culprit in kidney disease in diabetes.

Forbes JM, Coughlan MT, Cooper ME.

Diabetes. 2008 Jun;57(6):1446-54. Review.PMID: 18511445 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardiac inflammation associated with a Western diet is mediated via activation of RAGE by AGEs.

Tikellis C, Thomas MC, Harcourt BE, Coughlan MT, Pete J, Bialkowski K, Tan A, Bierhaus A, Cooper ME, Forbes JM.

Am J Physiol Endocrinol Metab. 2008 Aug;295(2):E323-30. Epub 2008 May 13.PMID: 18477705 [PubMed - indexed for MEDLINE]Related articlesFree article

Advanced glycation: implications in tissue damage and disease.

Gasser A, Forbes JM.

Protein Pept Lett. 2008;15(4):385-91.PMID: 18473952 [PubMed - indexed for MEDLINE]Related articles

Oxidative stress and advanced glycation in diabetic nephropathy.

Coughlan MT, Mibus AL, Forbes JM.

Ann N Y Acad Sci. 2008 Apr;1126:190-3.PMID: 18448815 [PubMed - indexed for MEDLINE]Related articles

Therapeutic interruption of advanced glycation in diabetic nephropathy: do all roads lead to Rome?

Sourris KC, Forbes JM, Cooper ME.

Ann N Y Acad Sci. 2008 Apr;1126:101-6. Review.PMID: 18448801 [PubMed - indexed for MEDLINE]Related articles

MKK3 signalling plays an essential role in leukocyte-mediated pancreatic injury in the multiple low-dose streptozotocin model.

Fukuda K, Tesch GH, Yap FY, Forbes JM, Flavell RA, Davis RJ, Nikolic-Paterson DJ.

Lab Invest. 2008 Apr;88(4):398-407. Epub 2008 Feb 18.PMID: 18283273 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-alpha-dependent pathway.

Thallas-Bonke V, Thorpe SR, Coughlan MT, Fukami K, Yap FY, Sourris KC, Penfold SA, Bach LA, Cooper ME, Forbes JM.

Diabetes. 2008 Feb;57(2):460-9. Epub 2007 Oct 24.PMID: 17959934 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of the AGE crosslink breaker, alagebrium, as a renoprotective agent in diabetes.

Coughlan MT, Forbes JM, Cooper ME.

Kidney Int Suppl. 2007 Aug;(106):S54-60. Review.PMID: 17653212 [PubMed - indexed for MEDLINE]Related articles

Advanced glycation of apolipoprotein A-I impairs its anti-atherogenic properties.

Hoang A, Murphy AJ, Coughlan MT, Thomas MC, Forbes JM, O'Brien R, Cooper ME, Chin-Dusting JP, Sviridov D.

Diabetologia. 2007 Aug;50(8):1770-9. Epub 2007 Jun 20.PMID: 17579831 [PubMed - indexed for MEDLINE]Related articles

AGE, RAGE, and ROS in diabetic nephropathy.

Tan AL, Forbes JM, Cooper ME.

Semin Nephrol. 2007 Mar;27(2):130-43. Review.PMID: 17418682 [PubMed - indexed for MEDLINE]Related articles

Diabetic nephropathy: where hemodynamics meets metabolism.

Forbes JM, Fukami K, Cooper ME.

Exp Clin Endocrinol Diabetes. 2007 Feb;115(2):69-84. Review.PMID: 17318765 [PubMed - indexed for MEDLINE]Related articles

Renal microvascular injury in diabetes: RAGE and redox signaling.

Coughlan MT, Cooper ME, Forbes JM.

Antioxid Redox Signal. 2007 Mar;9(3):331-42. Review.PMID: 17184182 [PubMed - indexed for MEDLINE]Related articles

Combination therapy with the advanced glycation end product cross-link breaker, alagebrium, and angiotensin converting enzyme inhibitors in diabetes: synergy or redundancy?

Coughlan MT, Thallas-Bonke V, Pete J, Long DM, Gasser A, Tong DC, Arnstein M, Thorpe SR, Cooper ME, Forbes JM.

Endocrinology. 2007 Feb;148(2):886-95. Epub 2006 Nov 16.PMID: 17110423 [PubMed - indexed for MEDLINE]Related articlesFree article

Connective tissue growth factor plays an important role in advanced glycation end product-induced tubular epithelial-to-mesenchymal transition: implications for diabetic renal disease.

Burns WC, Twigg SM, Forbes JM, Pete J, Tikellis C, Thallas-Bonke V, Thomas MC, Cooper ME, Kantharidis P.

J Am Soc Nephrol. 2006 Sep;17(9):2484-94. Epub 2006 Aug 16.PMID: 16914537 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel therapeutics for diabetic micro- and macrovascular complications.

Soro-Paavonen A, Forbes JM.

Curr Med Chem. 2006;13(15):1777-88. Review.PMID: 16787220 [PubMed - indexed for MEDLINE]Related articles

Solar rotation effects on the thermospheres of Mars and Earth.

Forbes JM, Bruinsma S, Lemoine FG.

Science. 2006 Jun 2;312(5778):1366-8.PMID: 16741117 [PubMed]Related articlesFree article

Below the radar: advanced glycation end products that detour "around the side". Is HbA1c not an accurate enough predictor of long term progression and glycaemic control in diabetes?

Forbes JM, Soldatos G, Thomas MC.

Clin Biochem Rev. 2005 Nov;26(4):123-34.PMID: 16648883 [PubMed]Related articlesFree article

A developmental nephron deficit in rats is associated with increased susceptibility to a secondary renal injury due to advanced glycation end-products.

Zimanyi MA, Denton KM, Forbes JM, Thallas-Bonke V, Thomas MC, Poon F, Black MJ.

Diabetologia. 2006 Apr;49(4):801-10. Epub 2006 Feb 23.PMID: 16496120 [PubMed - indexed for MEDLINE]Related articles

Advanced glycation end products and diabetic nephropathy.

Thomas MC, Forbes JM, Cooper ME.

Am J Ther. 2005 Nov-Dec;12(6):562-72. Review.PMID: 16280650 [PubMed - indexed for MEDLINE]Related articles

Performance of broiler chickens given whey in the food and/or drinking water.

Shariatmadari F, Forbes JM.

Br Poult Sci. 2005 Aug;46(4):498-505.PMID: 16268109 [PubMed - indexed for MEDLINE]Related articles

Interactions between renin angiotensin system and advanced glycation in the kidney.

Thomas MC, Tikellis C, Burns WM, Bialkowski K, Cao Z, Coughlan MT, Jandeleit-Dahm K, Cooper ME, Forbes JM.

J Am Soc Nephrol. 2005 Oct;16(10):2976-84. Epub 2005 Aug 17.PMID: 16107577 [PubMed - indexed for MEDLINE]Related articlesFree article

High glucose-induced impairment in insulin secretion is associated with reduction in islet glucokinase in a mouse model of susceptibility to islet dysfunction.

Kooptiwut S, Kebede M, Zraika S, Visinoni S, Aston-Mourney K, Favaloro J, Tikellis C, Thomas MC, Forbes JM, Cooper ME, Dunlop M, Proietto J, Andrikopoulos S.

J Mol Endocrinol. 2005 Aug;35(1):39-48.PMID: 16087720 [PubMed - indexed for MEDLINE]Related articlesFree article

Can advanced glycation end product inhibitors modulate more than one pathway to enhance renoprotection in diabetes?

Coughlan MT, Cooper ME, Forbes JM.

Ann N Y Acad Sci. 2005 Jun;1043:750-8. Review.PMID: 16037302 [PubMed - indexed for MEDLINE]Related articles

Low-molecular weight advanced glycation end products: markers of tissue AGE accumulation and more?

Thomas MC, Forbes JM, MacIsaac R, Jerums G, Cooper ME.

Ann N Y Acad Sci. 2005 Jun;1043:644-54. Review.PMID: 16037288 [PubMed - indexed for MEDLINE]Related articles

Rosiglitazone attenuates atherosclerosis in a model of insulin insufficiency independent of its metabolic effects.

Calkin AC, Forbes JM, Smith CM, Lassila M, Cooper ME, Jandeleit-Dahm KA, Allen TJ.

Arterioscler Thromb Vasc Biol. 2005 Sep;25(9):1903-9. Epub 2005 Jul 14.PMID: 16020748 [PubMed - indexed for MEDLINE]Related articlesFree article

Modulation of soluble receptor for advanced glycation end products by angiotensin-converting enzyme-1 inhibition in diabetic nephropathy.

Forbes JM, Thorpe SR, Thallas-Bonke V, Pete J, Thomas MC, Deemer ER, Bassal S, El-Osta A, Long DM, Panagiotopoulos S, Jerums G, Osicka TM, Cooper ME.

J Am Soc Nephrol. 2005 Aug;16(8):2363-72. Epub 2005 Jun 1.PMID: 15930093 [PubMed - indexed for MEDLINE]Related articlesFree article

Agents in development for the treatment of diabetic nephropathy.

Fukami K, Cooper ME, Forbes JM.

Expert Opin Investig Drugs. 2005 Mar;14(3):279-94. Review.PMID: 15833059 [PubMed - indexed for MEDLINE]Related articles

Identification of angiotensin converting enzyme 2 in the rodent retina.

Tikellis C, Johnston CI, Forbes JM, Burns WC, Thomas MC, Lew RA, Yarski M, Smith AI, Cooper ME.

Curr Eye Res. 2004 Dec;29(6):419-27.PMID: 15764086 [PubMed - indexed for MEDLINE]Related articles

Temporal renal expression of angiogenic growth factors and their receptors in experimental diabetes: role of the renin-angiotensin system.

Rizkalla B, Forbes JM, Cao Z, Boner G, Cooper ME.

J Hypertens. 2005 Jan;23(1):153-64.PMID: 15643138 [PubMed - indexed for MEDLINE]Related articles

Advanced glycation: how are we progressing to combat this web of sugar anomalies in diabetic nephropathy.

Forbes JM, Thallas-Bonke V, Cooper ME, Thomas MC.

Curr Pharm Des. 2004;10(27):3361-72. Review.PMID: 15544521 [PubMed - indexed for MEDLINE]Related articles

Attenuation of extracellular matrix accumulation in diabetic nephropathy by the advanced glycation end product cross-link breaker ALT-711 via a protein kinase C-alpha-dependent pathway.

Thallas-Bonke V, Lindschau C, Rizkalla B, Bach LA, Boner G, Meier M, Haller H, Cooper ME, Forbes JM.

Diabetes. 2004 Nov;53(11):2921-30.PMID: 15504973 [PubMed - indexed for MEDLINE]Related articlesFree article

The effects of valsartan on the accumulation of circulating and renal advanced glycation end products in experimental diabetes.

Forbes JM, Thomas MC, Thorpe SR, Alderson NL, Cooper ME.

Kidney Int Suppl. 2004 Nov;(92):S105-7. Review.PMID: 15485399 [PubMed - indexed for MEDLINE]Related articles

The ability of laying hens to regulate phosphorus intake when offered two feeds containing different levels of phosphorus.

Barkley GR, Miller HM, Forbes JM.

Br J Nutr. 2004 Aug;92(2):233-40.PMID: 15333154 [PubMed - indexed for MEDLINE]Related articles

Interactions between angiotensin II and NF-kappaB-dependent pathways in modulating macrophage infiltration in experimental diabetic nephropathy.

Lee FT, Cao Z, Long DM, Panagiotopoulos S, Jerums G, Cooper ME, Forbes JM.

J Am Soc Nephrol. 2004 Aug;15(8):2139-51.PMID: 15284299 [PubMed - indexed for MEDLINE]Related articlesFree article

Accelerated nephropathy in diabetic apolipoprotein e-knockout mouse: role of advanced glycation end products.

Lassila M, Seah KK, Allen TJ, Thallas V, Thomas MC, Candido R, Burns WC, Forbes JM, Calkin AC, Cooper ME, Jandeleit-Dahm KA.

J Am Soc Nephrol. 2004 Aug;15(8):2125-38.PMID: 15284298 [PubMed - indexed for MEDLINE]Related articlesFree article

Advanced glycation end product interventions reduce diabetes-accelerated atherosclerosis.

Forbes JM, Yee LT, Thallas V, Lassila M, Candido R, Jandeleit-Dahm KA, Thomas MC, Burns WC, Deemer EK, Thorpe SR, Cooper ME, Allen TJ.

Diabetes. 2004 Jul;53(7):1813-23. Erratum in: Diabetes. 2006 Mar;55(3):862. Thorpe, Susan M [corrected to Thorpe, Susan R]. PMID: 15220206 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of advanced glycation in reduced organic cation transport associated with experimental diabetes.

Thomas MC, Tikellis C, Kantharidis P, Burns WC, Cooper ME, Forbes JM.

J Pharmacol Exp Ther. 2004 Nov;311(2):456-66. Epub 2004 Jun 22.PMID: 15213250 [PubMed - indexed for MEDLINE]Related articlesFree article

Ramipril prevents microtubular changes in proximal tubules from streptozotocin diabetic rats.

Osicka TM, Forbes JM, Thallas V, Brammar GC, Jerums G, Comper WD.

Nephrology (Carlton). 2003 Aug;8(4):205-11.PMID: 15012722 [PubMed - indexed for MEDLINE]Related articles

Additive effects of hypertension and diabetes on renal cortical expression of PKC-alpha and -epsilon and alpha-tubulin but not PKC-beta 1 and -beta 2.

Osicka TM, Russo LM, Qiu ML, Brammar GC, Thallas V, Forbes JM, Comper WD, Jerums G.

J Hypertens. 2003 Dec;21(12):2399-407.PMID: 14654761 [PubMed - indexed for MEDLINE]Related articles

Superior renoprotective effects of combination therapy with ACE and AGE inhibition in the diabetic spontaneously hypertensive rat.

Davis BJ, Forbes JM, Thomas MC, Jerums G, Burns WC, Kawachi H, Allen TJ, Cooper ME.

Diabetologia. 2004 Jan;47(1):89-97. Epub 2003 Nov 29.PMID: 14647892 [PubMed - indexed for MEDLINE]Related articles

Increased renal vascular endothelial growth factor and angiopoietins by angiotensin II infusion is mediated by both AT1 and AT2 receptors.

Rizkalla B, Forbes JM, Cooper ME, Cao Z.

J Am Soc Nephrol. 2003 Dec;14(12):3061-71.PMID: 14638905 [PubMed - indexed for MEDLINE]Related articlesFree article