PubMed

Angiotensin II impairs endothelial function via tyrosine phosphorylation of the endothelial nitric oxide synthase.

Loot AE, Schreiber JG, Fisslthaler B, Fleming I.

J Exp Med. 2009 Nov 23. [Epub ahead of print]PMID: 19934023 [PubMed - as supplied by publisher]

NCCN Clinical Practice Guidelines in Oncology: Breast Cancer Screening and Diagnosis.

Bevers TB, Anderson BO, Bonaccio E, Buys S, Daly MB, Dempsey PJ, Farrar WB, Fleming I, Garber JE, Harris RE, Heerdt AS, Helvie M, Huff JG, Khakpour N, Khan SA, Krontiras H, Lyman G, Rafferty E, Shaw S, Smith ML, Tsangaris TN, Williams C, Yaneeklov T.

J Natl Compr Canc Netw. 2009 Nov;7(10):1060-96. No abstract available. PMID: 19930975 [PubMed - in process]

Inhibition of the soluble epoxide hydrolase by tyrosine nitration.

Barbosa-Sicard E, Frömel T, Keserü B, Brandes RP, Morisseau C, Hammock BD, Braun T, Krüger M, Fleming I.

J Biol Chem. 2009 Oct 9;284(41):28156-63. Epub 2009 Aug 24.PMID: 19704161 [PubMed - indexed for MEDLINE]Related articles

Hypoxia-induced pulmonary hypertension: comparison of soluble epoxide hydrolase deletion vs. inhibition.

Keserü B, Barbosa-Sicard E, Schermuly RT, Tanaka H, Hammock BD, Weissmann N, Fisslthaler B, Fleming I.

Cardiovasc Res. 2009 Sep 4. [Epub ahead of print]PMID: 19679679 [PubMed - as supplied by publisher]Related articles

CYP4A11 polymorphism correlates with coronary endothelial dysfunction in patients with coronary artery disease-The ENCORE Trials.

Hermann M, Hellermann JP, Quitzau K, Hoffmann MM, Gasser T, Meinertz T, Münzel T, Fleming I, Lüscher TF.

Atherosclerosis. 2009 Jun 17. [Epub ahead of print]PMID: 19615687 [PubMed - as supplied by publisher]Related articles

Activation and signaling by the AMP-activated protein kinase in endothelial cells.

Fisslthaler B, Fleming I.

Circ Res. 2009 Jul 17;105(2):114-27. Review.PMID: 19608989 [PubMed - indexed for MEDLINE]Related articles

Nitric oxide inhibits glomerular TGF-beta signaling via SMOC-1.

Dreieicher E, Beck KF, Lazaroski S, Boosen M, Tsalastra-Greul W, Beck M, Fleming I, Schaefer L, Pfeilschifter J.

J Am Soc Nephrol. 2009 Sep;20(9):1963-74. Epub 2009 Jul 2.PMID: 19578009 [PubMed - indexed for MEDLINE]Related articles

Growth patterns in children with sickle cell anemia during puberty.

Rhodes M, Akohoue SA, Shankar SM, Fleming I, Qi An A, Yu C, Acra S, Buchowski MS.

Pediatr Blood Cancer. 2009 Oct;53(4):635-41.PMID: 19544390 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin, insulin resistance, and platelet signaling in diabetes.

Randriamboavonjy V, Fleming I.

Diabetes Care. 2009 Apr;32(4):528-30. No abstract available. PMID: 19336637 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of the soluble epoxide hydrolase attenuates monocrotaline-induced pulmonary hypertension in rats.

Revermann M, Barbosa-Sicard E, Dony E, Schermuly RT, Morisseau C, Geisslinger G, Fleming I, Hammock BD, Brandes RP.

J Hypertens. 2009 Feb;27(2):322-31.PMID: 19226702 [PubMed - indexed for MEDLINE]Related articles

Anaphylactic shock depends on endothelial Gq/G11.

Korhonen H, Fisslthaler B, Moers A, Wirth A, Habermehl D, Wieland T, Schütz G, Wettschureck N, Fleming I, Offermanns S.

J Exp Med. 2009 Feb 16;206(2):411-20. Epub 2009 Jan 26.PMID: 19171764 [PubMed - indexed for MEDLINE]Related articlesFree article

The S1P(2) receptor expressed in human platelets is linked to the RhoA-Rho kinase pathway and is down regulated in type 2 diabetes.

Randriamboavonjy V, Badenhoop K, Schmidt H, Geisslinger G, Fisslthaler B, Fleming I.

Basic Res Cardiol. 2009 May;104(3):333-40. Epub 2009 Jan 12.PMID: 19139947 [PubMed - indexed for MEDLINE]Related articles

Angiotensin-converting enzyme (ACE) inhibitors modulate cellular retinol-binding protein 1 and adiponectin expression in adipocytes via the ACE-dependent signaling cascade.

Kohlstedt K, Gershome C, Trouvain C, Hofmann WK, Fichtlscherer S, Fleming I.

Mol Pharmacol. 2009 Mar;75(3):685-92. Epub 2008 Dec 29.PMID: 19114589 [PubMed - indexed for MEDLINE]Related articles

A design chart for estimation of horizontal displacement in municipal landfills.

Singh MK, Sharma JS, Fleming IR.

Waste Manag. 2009 May;29(5):1577-87. Epub 2008 Dec 12.PMID: 19070476 [PubMed - indexed for MEDLINE]Related articles

Cooperative robot assistant for retinal microsurgery.

Fleming I, Balicki M, Koo J, Iordachita I, Mitchell B, Handa J, Hager G, Taylor R.

Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist Interv. 2008;11(Pt 2):543-50.PMID: 18982647 [PubMed - indexed for MEDLINE]Related articles

Ablation monitoring with elastography: 2D in-vivo and 3D ex-vivo studies.

Rivaz H, Fleming I, Assumpcao L, Fichtinger G, Hamper U, Choti M, Hager G, Boctor E.

Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist Interv. 2008;11(Pt 2):458-66.PMID: 18982637 [PubMed - indexed for MEDLINE]Related articles

Atlantic salmon eggs favour sperm in competition that have similar major histocompatibility alleles.

Yeates SE, Einum S, Fleming IA, Megens HJ, Stet RJ, Hindar K, Holt WV, Van Look KJ, Gage MJ.

Proc Biol Sci. 2009 Feb 7;276(1656):559-66.PMID: 18854296 [PubMed - indexed for MEDLINE]Related articlesFree article

Epoxyeicosatrienoic acids are part of the VEGF-activated signaling cascade leading to angiogenesis.

Webler AC, Michaelis UR, Popp R, Barbosa-Sicard E, Murugan A, Falck JR, Fisslthaler B, Fleming I.

Am J Physiol Cell Physiol. 2008 Nov;295(5):C1292-301. Epub 2008 Sep 11.PMID: 18787075 [PubMed - indexed for MEDLINE]Related articlesFree article

Epoxyeicosatrienoic acids and the soluble epoxide hydrolase are determinants of pulmonary artery pressure and the acute hypoxic pulmonary vasoconstrictor response.

Keserü B, Barbosa-Sicard E, Popp R, Fisslthaler B, Dietrich A, Gudermann T, Hammock BD, Falck JR, Weissmann N, Busse R, Fleming I.

FASEB J. 2008 Dec;22(12):4306-15. Epub 2008 Aug 25.PMID: 18725458 [PubMed - indexed for MEDLINE]Related articles

Does within-population variation in fish egg size reflect maternal influences on optimal values?

Einum S, Fleming IA.

Am Nat. 2002 Dec;160(6):756-65.PMID: 18707463 [PubMed]Related articles

Role of cytochrome P450-dependent transient receptor potential V4 activation in flow-induced vasodilatation.

Loot AE, Popp R, Fisslthaler B, Vriens J, Nilius B, Fleming I.

Cardiovasc Res. 2008 Dec 1;80(3):445-52. Epub 2008 Aug 5.PMID: 18682435 [PubMed - indexed for MEDLINE]Related articles

Impaired interaction of platelets with endothelial progenitor cells in patients with cardiovascular risk factors.

Dernbach E, Randriamboavonjy V, Fleming I, Zeiher AM, Dimmeler S, Urbich C.

Basic Res Cardiol. 2008 Nov;103(6):572-81. Epub 2008 Jul 5.PMID: 18604625 [PubMed - indexed for MEDLINE]Related articles

Synergistic inhibition of ErbB signaling by combined treatment with seliciclib and ErbB-targeting agents.

Fleming IN, Hogben M, Frame S, McClue SJ, Green SR.

Clin Cancer Res. 2008 Jul 1;14(13):4326-35.PMID: 18594016 [PubMed - indexed for MEDLINE]Related articlesFree article

Double tribble: two TRIB3 variants, insulin, Akt, and eNOS.

Fleming I.

Arterioscler Thromb Vasc Biol. 2008 Jul;28(7):1216-8. No abstract available. PMID: 18565845 [PubMed - indexed for MEDLINE]Related articlesFree article

AT1-receptor blockade by telmisartan upregulates GTP-cyclohydrolase I and protects eNOS in diabetic rats.

Wenzel P, Schulz E, Oelze M, Müller J, Schuhmacher S, Alhamdani MS, Debrezion J, Hortmann M, Reifenberg K, Fleming I, Münzel T, Daiber A.

Free Radic Biol Med. 2008 Sep 1;45(5):619-26. Epub 2008 May 23.PMID: 18539157 [PubMed - indexed for MEDLINE]Related articles

Inhibition of endothelial nitric oxide synthase activity by proline-rich tyrosine kinase 2 in response to fluid shear stress and insulin.

Fisslthaler B, Loot AE, Mohamed A, Busse R, Fleming I.

Circ Res. 2008 Jun 20;102(12):1520-8. Epub 2008 May 15.PMID: 18483407 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytochrome P450 2C9-induced angiogenesis is dependent on EphB4.

Webler AC, Popp R, Korff T, Michaelis UR, Urbich C, Busse R, Fleming I.

Arterioscler Thromb Vasc Biol. 2008 Jun;28(6):1123-9. Epub 2008 Mar 13.PMID: 18340006 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of cytochrome P450 2C epoxygenases in hypoxia-induced cell migration and angiogenesis in retinal endothelial cells.

Michaelis UR, Xia N, Barbosa-Sicard E, Falck JR, Fleming I.

Invest Ophthalmol Vis Sci. 2008 Mar;49(3):1242-7.PMID: 18326754 [PubMed - indexed for MEDLINE]Related articlesFree article

Neuronal desynchronization as a trigger for seizure generation.

Li Y, Fleming IN, Colpan ME, Mogul DJ.

IEEE Trans Neural Syst Rehabil Eng. 2008 Feb;16(1):62-73.PMID: 18303807 [PubMed - indexed for MEDLINE]Related articles

Vascular cytochrome p450 enzymes: physiology and pathophysiology.

Fleming I.

Trends Cardiovasc Med. 2008 Jan;18(1):20-5. Review.PMID: 18206805 [PubMed - indexed for MEDLINE]Related articles

Platelet sarcoplasmic endoplasmic reticulum Ca2+-ATPase and mu-calpain activity are altered in type 2 diabetes mellitus and restored by rosiglitazone.

Randriamboavonjy V, Pistrosch F, Bölck B, Schwinger RH, Dixit M, Badenhoop K, Cohen RA, Busse R, Fleming I.

Circulation. 2008 Jan 1;117(1):52-60. Epub 2007 Dec 10.PMID: 18071073 [PubMed - indexed for MEDLINE]Related articlesFree article

Shear stress-induced activation of the AMP-activated protein kinase regulates FoxO1a and angiopoietin-2 in endothelial cells.

Dixit M, Bess E, Fisslthaler B, Härtel FV, Noll T, Busse R, Fleming I.

Cardiovasc Res. 2008 Jan;77(1):160-8. Epub 2007 Sep 19.PMID: 18006475 [PubMed - indexed for MEDLINE]Related articlesFree article

Family physicians' perceptions of academic detailing: a quantitative and qualitative study.

Allen M, Ferrier S, O'Connor N, Fleming I.

BMC Med Educ. 2007 Oct 12;7:36.PMID: 17935614 [PubMed - indexed for MEDLINE]Related articlesFree article

Breast cancer risk reduction.

Bevers TB, Armstrong DK, Arun B, Carlson RW, Cowan KH, Daly MB, Fleming I, Garber JE, Gemignani M, Gradishar WJ, Krontiras H, Kulkarni S, Laronga C, Lawton T, Loftus L, Macdonald DJ, Mahoney MC, Merajver SD, Seewaldt V, Sellin RV, Shapiro CL, Singletary E, Ward JH; National Comprehensive Cancer Network (NCCN).

J Natl Compr Canc Netw. 2007 Sep;5(8):676-701. No abstract available. PMID: 17927926 [PubMed - indexed for MEDLINE]Related articles

Comparison of slope stability in two Brazilian municipal landfills.

Gharabaghi B, Singh MK, Inkratas C, Fleming IR, McBean E.

Waste Manag. 2008;28(9):1509-17. Epub 2007 Sep 25.PMID: 17897819 [PubMed - indexed for MEDLINE]Related articles

Epoxyeicosatrienoic acids regulate Trp channel dependent Ca2+ signaling and hyperpolarization in endothelial cells.

Fleming I, Rueben A, Popp R, Fisslthaler B, Schrodt S, Sander A, Haendeler J, Falck JR, Morisseau C, Hammock BD, Busse R.

Arterioscler Thromb Vasc Biol. 2007 Dec;27(12):2612-8. Epub 2007 Sep 13.PMID: 17872452 [PubMed - indexed for MEDLINE]Related articlesFree article

DiscrEET regulators of homeostasis: epoxyeicosatrienoic acids, cytochrome P450 epoxygenases and vascular inflammation.

Fleming I.

Trends Pharmacol Sci. 2007 Sep;28(9):448-52. Epub 2007 Aug 30.PMID: 17764757 [PubMed - indexed for MEDLINE]Related articles

Cytochrome P450 2C9 is involved in flow-dependent vasodilation of peripheral conduit arteries in healthy subjects and in patients with chronic heart failure.

Fischer D, Landmesser U, Spiekermann S, Hilfiker-Kleiner D, Hospely M, Müller M, Busse R, Fleming I, Drexler H.

Eur J Heart Fail. 2007 Aug;9(8):770-5. Epub 2007 Jun 15.PMID: 17572144 [PubMed - indexed for MEDLINE]Related articles

Epoxyeicosatrienoic acids affect electrolyte transport in renal tubular epithelial cells: dependence on cyclooxygenase and cell polarity.

Nüsing RM, Schweer H, Fleming I, Zeldin DC, Wegmann M.

Am J Physiol Renal Physiol. 2007 Jul;293(1):F288-98. Epub 2007 May 9.PMID: 17494091 [PubMed - indexed for MEDLINE]Related articlesFree article

A critical review of adaptive genetic variation in Atlantic salmon: implications for conservation.

Garcia de Leaniz C, Fleming IA, Einum S, Verspoor E, Jordan WC, Consuegra S, Aubin-Horth N, Lajus D, Letcher BH, Youngson AF, Webb JH, Vøllestad LA, Villanueva B, Ferguson A, Quinn TP.

Biol Rev Camb Philos Soc. 2007 May;82(2):173-211. Review.PMID: 17437557 [PubMed - indexed for MEDLINE]Related articles

Factors influencing hospital costs of lung cancer patients in Northern Ireland.

Fleming I, Monaghan P, Gavin A, O'Neill C.

Eur J Health Econ. 2008 Feb;9(1):79-86. Epub 2007 Mar 31.PMID: 17401593 [PubMed - indexed for MEDLINE]Related articles

The ADMA/DDAH pathway is a critical regulator of endothelial cell motility.

Wojciak-Stothard B, Torondel B, Tsang LY, Fleming I, Fisslthaler B, Leiper JM, Vallance P.

J Cell Sci. 2007 Mar 15;120(Pt 6):929-42. Epub 2007 Feb 27. Erratum in: J Cell Sci. 2007 Apr 15;120(Pt 8):1502. PMID: 17327280 [PubMed - indexed for MEDLINE]Related articlesFree article

The effects of COX-2 selective and non-selective NSAIDs on the initiation and progression of atherosclerosis in ApoE-/- mice.

Metzner J, Popp L, Marian C, Schmidt R, Manderscheid C, Renne C, Fisslthaler B, Fleming I, Busse R, Geisslinger G, Niederberger E.

J Mol Med. 2007 Jun;85(6):623-33. Epub 2007 Feb 22.PMID: 17318614 [PubMed - indexed for MEDLINE]Related articles

Of chickens and eggs: diverging propagule size of iteroparous and semelparous organisms.

Einum S, Fleming IA.

Evolution. 2007 Jan;61(1):232-8.PMID: 17300442 [PubMed - indexed for MEDLINE]Related articles

Genetically enhanced growth causes increased mortality in hypoxic environments.

Sundt-Hansen L, Sundström LF, Einum S, Hindar K, Fleming IA, Devlin RH.

Biol Lett. 2007 Apr 22;3(2):165-8.PMID: 17272234 [PubMed - indexed for MEDLINE]Related articlesFree article

Fluid shear stress and NO decrease the activity of the hydroxy-methylglutaryl coenzyme A reductase in endothelial cells via the AMP-activated protein kinase and FoxO1.

Fisslthaler B, Fleming I, Keserü B, Walsh K, Busse R.

Circ Res. 2007 Feb 2;100(2):e12-21. Epub 2007 Jan 11.PMID: 17218607 [PubMed - indexed for MEDLINE]Related articlesFree article

Epoxyeicosatrienoic acids, cell signaling and angiogenesis.

Fleming I.

Prostaglandins Other Lipid Mediat. 2007 Jan;82(1-4):60-7. Epub 2006 Jul 11. Review.PMID: 17164133 [PubMed - indexed for MEDLINE]Related articles

Vascular endothelium and blood flow.

Busse R, Fleming I.

Handb Exp Pharmacol. 2006;(176 Pt 2):43-78. Review.PMID: 16999224 [PubMed - indexed for MEDLINE]Related articles

Realizing its potential: the intermediate conductance Ca2+-activated K+ channel (KCa3.1) and the regulation of blood pressure.

Fleming I.

Circ Res. 2006 Sep 1;99(5):462-4. Review. No abstract available. PMID: 16946141 [PubMed - indexed for MEDLINE]Related articlesFree article

NADPH oxidase accounts for enhanced superoxide production and impaired endothelium-dependent smooth muscle relaxation in BKbeta1-/- mice.

Oelze M, Warnholtz A, Faulhaber J, Wenzel P, Kleschyov AL, Coldewey M, Hink U, Pongs O, Fleming I, Wassmann S, Meinertz T, Ehmke H, Daiber A, Münzel T.

Arterioscler Thromb Vasc Biol. 2006 Aug;26(8):1753-9. Epub 2006 Jun 8.PMID: 16763163 [PubMed - indexed for MEDLINE]Related articlesFree article