PubMed

Quantification of the relationship between glycemia and beta-cell mass adaptation in vivo.

Atkinson LL, Topp BG, Au J, Vinerian HV, Dhatt N, Finegood DT.

Can J Physiol Pharmacol. 2009 Aug;87(8):602-9.PMID: 19767884 [PubMed - in process]Related articles

International perspectives on the physical inactivity crisis--structural solutions over evidence generation?

Bauman A, Finegood DT, Matsudo V.

Prev Med. 2009 Oct;49(4):309-12. Epub 2009 Jul 30.PMID: 19647014 [PubMed - in process]Related articles

Getting from analysis to action: framing obesity research, policy and practice with a solution-oriented complex systems lens.

Finegood DT, Karanfil O, Matteson CL.

Healthc Pap. 2008;9(1):36-41; discussion 62-67.PMID: 18974663 [PubMed - indexed for MEDLINE]Related articles

Grand challenges in chronic non-communicable diseases.

Daar AS, Singer PA, Persad DL, Pramming SK, Matthews DR, Beaglehole R, Bernstein A, Borysiewicz LK, Colagiuri S, Ganguly N, Glass RI, Finegood DT, Koplan J, Nabel EG, Sarna G, Sarrafzadegan N, Smith R, Yach D, Bell J.

Nature. 2007 Nov 22;450(7169):494-6. No abstract available. PMID: 18033288 [PubMed - indexed for MEDLINE]Related articles

Effect of chronic rosiglitazone, metformin and glyburide treatment on beta-cell mass, function and insulin sensitivity in mZDF rats.

Atkinson LL, McDonald-Dyck C, Benkoczi C, Finegood DT.

Diabetes Obes Metab. 2008 Sep;10(9):780-90. Epub 2007 Oct 26.PMID: 17970758 [PubMed - indexed for MEDLINE]Related articles

A quantitative comparison of rates of phagocytosis and digestion of apoptotic cells by macrophages from normal (BALB/c) and diabetes-prone (NOD) mice.

Marée AF, Komba M, Finegood DT, Edelstein-Keshet L.

J Appl Physiol. 2008 Jan;104(1):157-69. Epub 2007 Oct 25.PMID: 17962581 [PubMed - indexed for MEDLINE]Related articlesFree article

Dynamics of insulin sensitivity, -cell function, and -cell mass during the development of diabetes in fa/fa rats.

Topp BG, Atkinson LL, Finegood DT.

Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1730-5. Epub 2007 Sep 25.PMID: 17895283 [PubMed - indexed for MEDLINE]Related articlesFree article

Pronounced cytosolic aggregation of cellular prion protein in pancreatic beta-cells in response to hyperglycemia.

Strom A, Wang GS, Reimer R, Finegood DT, Scott FW.

Lab Invest. 2007 Feb;87(2):139-49. Epub 2006 Dec 4.PMID: 17146448 [PubMed - indexed for MEDLINE]Related articlesFree article

Modelling the onset of Type 1 diabetes: can impaired macrophage phagocytosis make the difference between health and disease?

Marée AF, Kublik R, Finegood DT, Edelstein-Keshet L.

Philos Transact A Math Phys Eng Sci. 2006 May 15;364(1842):1267-82.PMID: 16608707 [PubMed - indexed for MEDLINE]Related articlesFree article

A deficiency in the in vivo clearance of apoptotic cells is a feature of the NOD mouse.

O'Brien BA, Geng X, Orteu CH, Huang Y, Ghoreishi M, Zhang Y, Bush JA, Li G, Finegood DT, Dutz JP.

J Autoimmun. 2006 Mar;26(2):104-15. Epub 2006 Jan 20.PMID: 16431079 [PubMed - indexed for MEDLINE]Related articles

Quantifying macrophage defects in type 1 diabetes.

Marée AF, Komba M, Dyck C, Łabecki M, Finegood DT, Edelstein-Keshet L.

J Theor Biol. 2005 Apr 21;233(4):533-51. Epub 2005 Jan 20.PMID: 15748914 [PubMed - indexed for MEDLINE]Related articles

Metabolic adaptations to chronic glucose infusion in rats.

Topp BG, McArthur MD, Finegood DT.

Diabetologia. 2004 Sep;47(9):1602-10. Epub 2004 Sep 2.PMID: 15349726 [PubMed - indexed for MEDLINE]Related articles

Obesity, inflammation and type II diabetes.

Finegood DT.

Int J Obes Relat Metab Disord. 2003 Dec;27 Suppl 3:S4-5. Review. No abstract available. PMID: 14704735 [PubMed - indexed for MEDLINE]Related articles

Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood.

Trudeau JD, Kelly-Smith C, Verchere CB, Elliott JF, Dutz JP, Finegood DT, Santamaria P, Tan R.

J Clin Invest. 2003 Jan;111(2):217-23.PMID: 12531877 [PubMed - indexed for MEDLINE]Related articlesFree article

Defining optimal immunosuppression for islet transplantation based on reduced diabetogenicity in canine islet autografts.

Shapiro AM, Geng Hao E, Lakey JR, Finegood DT, Rajotte RV, Kneteman NM.

Transplantation. 2002 Dec 15;74(11):1522-8.PMID: 12490784 [PubMed - indexed for MEDLINE]Related articles

Phagocytosis of apoptotic cells by macrophages from NOD mice is reduced.

O'Brien BA, Huang Y, Geng X, Dutz JP, Finegood DT.

Diabetes. 2002 Aug;51(8):2481-8.PMID: 12145161 [PubMed - indexed for MEDLINE]Related articlesFree article

beta-cell neogenesis during prolonged hyperglycemia in rats.

Lipsett M, Finegood DT.

Diabetes. 2002 Jun;51(6):1834-41.PMID: 12031971 [PubMed - indexed for MEDLINE]Related articlesFree article

The evolution of beta-cell dysfunction and insulin resistance in type 2 diabetes.

Bergman RN, Finegood DT, Kahn SE.

Eur J Clin Invest. 2002 Jun;32 Suppl 3:35-45. Review.PMID: 12028373 [PubMed - indexed for MEDLINE]Related articles

Clearance of apoptotic beta-cells is reduced in neonatal autoimmune diabetes-prone rats.

O'Brien BA, Fieldus WE, Field CJ, Finegood DT.

Cell Death Differ. 2002 Apr;9(4):457-64.PMID: 11965499 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term treatment with the dipeptidyl peptidase IV inhibitor P32/98 causes sustained improvements in glucose tolerance, insulin sensitivity, hyperinsulinemia, and beta-cell glucose responsiveness in VDF (fa/fa) Zucker rats.

Pospisilik JA, Stafford SG, Demuth HU, Brownsey R, Parkhouse W, Finegood DT, McIntosh CH, Pederson RA.

Diabetes. 2002 Apr;51(4):943-50.PMID: 11916911 [PubMed - indexed for MEDLINE]Related articlesFree article

Beta-cell deterioration--prospects for reversal or prevention.

Finegood DT, Topp BG.

Diabetes Obes Metab. 2001 Aug;3 Suppl 1:S20-7. Review. No abstract available. PMID: 11685825 [PubMed - indexed for MEDLINE]Related articles

beta-cell deterioration - prospects for reversal or prevention.

Finegood DT, Topp BG.

Diabetes Obes Metab. 2001 Aug;3 Suppl 1:20-27. No abstract available. PMID: 11683855 [PubMed - as supplied by publisher]Related articles

Effect of glucagon-like peptide 1 on non-insulin-mediated glucose uptake in the elderly patient with diabetes.

Meneilly GS, McIntosh CH, Pederson RA, Habener JF, Gingerich R, Egan JM, Finegood DT, Elahi D.

Diabetes Care. 2001 Nov;24(11):1951-6.PMID: 11679463 [PubMed - indexed for MEDLINE]Related articlesFree article

Beta-cell function and visceral fat in lactating women with a history of gestational diabetes.

McManus RM, Cunningham I, Watson A, Harker L, Finegood DT.

Metabolism. 2001 Jun;50(6):715-9.PMID: 11398150 [PubMed - indexed for MEDLINE]Related articles

Beta-cell mass dynamics in Zucker diabetic fatty rats. Rosiglitazone prevents the rise in net cell death.

Finegood DT, McArthur MD, Kojwang D, Thomas MJ, Topp BG, Leonard T, Buckingham RE.

Diabetes. 2001 May;50(5):1021-9.PMID: 11334404 [PubMed - indexed for MEDLINE]Related articlesFree article

Dietary P(i) deprivation in rats affects liver cAMP, glycogen, key steps of gluconeogenesis and glucose production.

Xie W, Tran TL, Finegood DT, van de Werve G.

Biochem J. 2000 Nov 15;352 Pt 1:227-32.PMID: 11062077 [PubMed - indexed for MEDLINE]Related articlesFree article

A model of beta-cell mass, insulin, and glucose kinetics: pathways to diabetes.

Topp B, Promislow K, deVries G, Miura RM, Finegood DT.

J Theor Biol. 2000 Oct 21;206(4):605-19.PMID: 11013117 [PubMed - indexed for MEDLINE]Related articles

Minimal-model estimates of insulin sensitivity are insensitive to errors in glucose effectiveness.

McDonald C, Dunaif A, Finegood DT.

J Clin Endocrinol Metab. 2000 Jul;85(7):2504-8.PMID: 10902801 [PubMed - indexed for MEDLINE]Related articlesFree article

Neonatal beta-cell apoptosis: a trigger for autoimmune diabetes?

Trudeau JD, Dutz JP, Arany E, Hill DJ, Fieldus WE, Finegood DT.

Diabetes. 2000 Jan;49(1):1-7. Review.PMID: 10615942 [PubMed - indexed for MEDLINE]Related articlesFree article

Prior streptozotocin treatment does not inhibit pancreas regeneration after 90% pancreatectomy in rats.

Finegood DT, Weir GC, Bonner-Weir S.

Am J Physiol. 1999 May;276(5 Pt 1):E822-7.PMID: 10329974 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose effectiveness is the major determinant of intravenous glucose tolerance in the rat.

McArthur MD, You D, Klapstein K, Finegood DT.

Am J Physiol. 1999 Apr;276(4 Pt 1):E739-46.PMID: 10198311 [PubMed - indexed for MEDLINE]Related articlesFree article

Relation among left ventricular mass, insulin resistance, and blood pressure in nonobese subjects.

Phillips RA, Krakoff LR, Dunaif A, Finegood DT, Gorlin R, Shimabukuro S.

J Clin Endocrinol Metab. 1998 Dec;83(12):4284-8.PMID: 9851765 [PubMed - indexed for MEDLINE]Related articlesFree article

Assessing insulin sensitivity in the cat: evaluation of the hyperinsulinemic euglycemic clamp and the minimal model analysis.

Petrus DJ, Jackson MW, Kemnitz JW, Finegood DT, Panciera D.

Res Vet Sci. 1998 Sep-Oct;65(2):179-81.PMID: 9839901 [PubMed - indexed for MEDLINE]Related articles

High fructose intake significantly reduces kidney copper concentrations in diabetic, islet transplanted rats.

Bell RC, Sakanashi TM, Keen CL, Finegood DT.

Biol Trace Elem Res. 1998 Feb;61(2):137-49.PMID: 9517486 [PubMed - indexed for MEDLINE]Related articles

Insulin levels increase during glycemic normalization following transplantation of syngeneic islets in diabetic rats.

Bell RC, Finegood DT.

Can J Physiol Pharmacol. 1997 Aug;75(8):952-8.PMID: 9360008 [PubMed - indexed for MEDLINE]Related articles

Factors affecting glucose tolerance in hereditary hemochromatosis.

Hramiak IM, Finegood DT, Adams PC.

Clin Invest Med. 1997 Apr;20(2):110-8.PMID: 9088667 [PubMed - indexed for MEDLINE]Related articles

Apoptosis participates in the remodeling of the endocrine pancreas in the neonatal rat.

Scaglia L, Cahill CJ, Finegood DT, Bonner-Weir S.

Endocrinology. 1997 Apr;138(4):1736-41.PMID: 9075738 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced glucose effectiveness associated with reduced insulin release: an artifact of the minimal-model method.

Finegood DT, Tzur D.

Am J Physiol. 1996 Sep;271(3 Pt 1):E485-95.PMID: 8843742 [PubMed - indexed for MEDLINE]Related articles

Long-term normalization of GLUT-4 protein content in skeletal muscle of diabetic rats following islet transplantation.

Davalli AM, Napoli R, Weitgasser R, Capotorto JV, Hirshman MF, Finegood DT, Bonner-Weir S, Horton ES, Weir GC.

J Endocrinol. 1996 Aug;150(2):255-63.PMID: 8869592 [PubMed - indexed for MEDLINE]Related articles

A comparison of the effects of n-3 fatty acids from linseed oil and fish oil in well-controlled type II diabetes.

McManus RM, Jumpson J, Finegood DT, Clandinin MT, Ryan EA.

Diabetes Care. 1996 May;19(5):463-7.PMID: 8732710 [PubMed - indexed for MEDLINE]Related articles

Glycogen synthase polymorphism, insulin resistance and hypertension.

Gharavi AG, Phillips RA, Finegood DT, Lipkowitz MS.

Blood Press. 1996 Mar;5(2):86-90.PMID: 8860096 [PubMed - indexed for MEDLINE]Related articles

Beta-cell dysfunction independent of obesity and glucose intolerance in the polycystic ovary syndrome.

Dunaif A, Finegood DT.

J Clin Endocrinol Metab. 1996 Mar;81(3):942-7.PMID: 8772555 [PubMed - indexed for MEDLINE]Related articles

Consequences of high dietary fructose in the islet-transplanted rat with suboptimal beta-cell mass.

Bell RC, Ryan EA, Finegood DT.

Am J Physiol. 1996 Feb;270(2 Pt 1):E292-8.PMID: 8779951 [PubMed - indexed for MEDLINE]Related articles

Hemodynamic and humoral correlates of insulin resistance in non-obese borderline hypertensives--a preliminary report.

Phillips RA, Krakoff LR, Finegood DT, Dunaif A.

Blood Press Suppl. 1996;1:72-4. No abstract available. PMID: 9162444 [PubMed - indexed for MEDLINE]Related articles

Islet transplantation in diabetic Lewis rats--a comparison of the transplantation sites kidney and spleen capsule.

Weitgasser R, Davalli AM, Capotorto JV, Finegood DT, Bonner-Weir S, Weir GC.

Acta Med Austriaca. 1996;23(5):156-9.PMID: 9082744 [PubMed - indexed for MEDLINE]Related articles

Long-term normalization of GLUT 4 protein content in skeletal muscle of streptozotocin-diabetic Lewis rats after islet transplantation.

Weitgasser R, Davalli AM, Napoli R, Capotorto JV, Finegood DT, Bonner-Weir S, Weir GC.

Transplant Proc. 1995 Dec;27(6):3184-5.PMID: 8539901 [PubMed - indexed for MEDLINE]Related articles

Long-term consequences in offspring of diabetes in pregnancy: studies with syngeneic islet-transplanted streptozotocin-diabetic rats.

Ryan EA, Liu D, Bell RC, Finegood DT, Crawford J.

Endocrinology. 1995 Dec;136(12):5587-92.PMID: 7588312 [PubMed - indexed for MEDLINE]Related articles

Splanchnic infusions of short chain fatty acids do not change insulin sensitivity of pigs.

McBurney MI, Apps KV, Finegood DT.

J Nutr. 1995 Oct;125(10):2571-6.PMID: 7562092 [PubMed - indexed for MEDLINE]Related articlesFree article

Estimation of rat body composition by means of electromagnetic scanning is altered by duration of anesthesia.

Tobin BW, Finegood DT.

J Nutr. 1995 Jun;125(6):1512-20.PMID: 7782905 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin action in previously diabetic rats receiving graded numbers of islets of Langerhans.

Tobin BW, Lewis JT, Tobin BL, Finegood DT.

Transplantation. 1995 May 27;59(10):1464-9.PMID: 7770935 [PubMed - indexed for MEDLINE]Related articles