PubMed

In vivo metabolic phenotyping of myocardial substrate metabolism in rodents: differential efficacy of metformin and rosiglitazone monotherapy.

Shoghi KI, Finck BN, Schechtman KB, Sharp T, Herrero P, Gropler RJ, Welch MJ.

Circ Cardiovasc Imaging. 2009 Sep;2(5):373-81. Epub 2009 Jul 21.PMID: 19808625 [PubMed - indexed for MEDLINE]Related articles

Dynamic and differential regulation of proteins that coat lipid droplets in fatty liver dystrophic mice.

Hall AM, Brunt EM, Chen Z, Viswakarma N, Reddy JK, Wolins NE, Finck BN.

J Lipid Res. 2009 Sep 11. [Epub ahead of print]PMID: 19749180 [PubMed - as supplied by publisher]Related articlesFree article

Hepatic Expression of Cell Death-inducing DFFA-like Effector C in Obese Subjects Is Reduced by Marked Weight Loss.

Hall AM, Brunt EM, Klein S, Finck BN.

Obesity (Silver Spring). 2009 Aug 6. [Epub ahead of print]PMID: 19661960 [PubMed - as supplied by publisher]Related articles

FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response.

Potthoff MJ, Inagaki T, Satapati S, Ding X, He T, Goetz R, Mohammadi M, Finck BN, Mangelsdorf DJ, Kliewer SA, Burgess SC.

Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10853-8. Epub 2009 Jun 16.PMID: 19541642 [PubMed - indexed for MEDLINE]Related articles

Dietary fat and carbohydrates differentially alter insulin sensitivity during caloric restriction.

Kirk E, Reeds DN, Finck BN, Mayurranjan SM, Patterson BW, Klein S.

Gastroenterology. 2009 May;136(5):1552-60. Epub 2009 Jan 25. Erratum in: Gastroenterology. 2009 Jul;137(1):393. Mayurranjan, Mitra S [corrected to Mayurranjan S Mitra]. PMID: 19208352 [PubMed - indexed for MEDLINE]Related articles

Lipin 2 is a liver-enriched phosphatidate phosphohydrolase enzyme that is dynamically regulated by fasting and obesity in mice.

Gropler MC, Harris TE, Hall AM, Wolins NE, Gross RW, Han X, Chen Z, Finck BN.

J Biol Chem. 2009 Mar 13;284(11):6763-72. Epub 2009 Jan 10.PMID: 19136718 [PubMed - indexed for MEDLINE]Related articles

Alterations in hepatic metabolism in fld mice reveal a role for lipin 1 in regulating VLDL-triacylglyceride secretion.

Chen Z, Gropler MC, Norris J, Lawrence JC Jr, Harris TE, Finck BN.

Arterioscler Thromb Vasc Biol. 2008 Oct;28(10):1738-44. Epub 2008 Jul 31.PMID: 18669885 [PubMed - indexed for MEDLINE]Related articlesFree article

Time course of alterations in myocardial glucose utilization in the Zucker diabetic fatty rat with correlation to gene expression of glucose transporters: a small-animal PET investigation.

Shoghi KI, Gropler RJ, Sharp T, Herrero P, Fettig N, Su Y, Mitra MS, Kovacs A, Finck BN, Welch MJ.

J Nucl Med. 2008 Aug;49(8):1320-7. Epub 2008 Jul 16.PMID: 18632819 [PubMed - indexed for MEDLINE]Related articlesFree article

Exercise but not diet-induced weight loss decreases skeletal muscle inflammatory gene expression in frail obese elderly persons.

Lambert CP, Wright NR, Finck BN, Villareal DT.

J Appl Physiol. 2008 Aug;105(2):473-8. Epub 2008 Jun 5.PMID: 18535122 [PubMed - indexed for MEDLINE]Related articlesFree article

PPARs/RXRs in Cardiovascular Physiology and Disease.

Finck BN, Chinetti G, Staels B.

PPAR Res. 2008;2008:173780. No abstract available. PMID: 18389071 [PubMed - in process]Related articlesFree article

The PPARalpha-PGC-1alpha Axis Controls Cardiac Energy Metabolism in Healthy and Diseased Myocardium.

Duncan JG, Finck BN.

PPAR Res. 2008;2008:253817.PMID: 18288281 [PubMed - in process]Related articlesFree article

Hepatic lipin 1beta expression is diminished in insulin-resistant obese subjects and is reactivated by marked weight loss.

Croce MA, Eagon JC, LaRiviere LL, Korenblat KM, Klein S, Finck BN.

Diabetes. 2007 Sep;56(9):2395-9. Epub 2007 Jun 11.PMID: 17563064 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) regulatory cascade in cardiac physiology and disease.

Finck BN, Kelly DP.

Circulation. 2007 May 15;115(19):2540-8. No abstract available. PMID: 17502589 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of marked weight loss on adiponectin gene expression and plasma concentrations.

Coughlin CC, Finck BN, Eagon JC, Halpin VJ, Magkos F, Mohammed BS, Klein S.

Obesity (Silver Spring). 2007 Mar;15(3):640-5.PMID: 17372314 [PubMed - indexed for MEDLINE]Related articles

CD36 deficiency rescues lipotoxic cardiomyopathy.

Yang J, Sambandam N, Han X, Gross RW, Courtois M, Kovacs A, Febbraio M, Finck BN, Kelly DP.

Circ Res. 2007 Apr 27;100(8):1208-17. Epub 2007 Mar 15.PMID: 17363697 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-resistant heart exhibits a mitochondrial biogenic response driven by the peroxisome proliferator-activated receptor-alpha/PGC-1alpha gene regulatory pathway.

Duncan JG, Fong JL, Medeiros DM, Finck BN, Kelly DP.

Circulation. 2007 Feb 20;115(7):909-17. Epub 2007 Jan 29.PMID: 17261654 [PubMed - indexed for MEDLINE]Related articlesFree article

OXPAT/PAT-1 is a PPAR-induced lipid droplet protein that promotes fatty acid utilization.

Wolins NE, Quaynor BK, Skinner JR, Tzekov A, Croce MA, Gropler MC, Varma V, Yao-Borengasser A, Rasouli N, Kern PA, Finck BN, Bickel PE.

Diabetes. 2006 Dec;55(12):3418-28.PMID: 17130488 [PubMed - indexed for MEDLINE]Related articlesFree article

ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome.

Schneider JG, Finck BN, Ren J, Standley KN, Takagi M, Maclean KH, Bernal-Mizrachi C, Muslin AJ, Kastan MB, Semenkovich CF.

Cell Metab. 2006 Nov;4(5):377-89.PMID: 17084711 [PubMed - indexed for MEDLINE]Related articles

Synthesis and evaluation of a bromine-76-labeled PPARgamma antagonist 2-bromo-5-nitro-N-phenylbenzamide.

Lee H, Finck BN, Jones LA, Welch MJ, Mach RH.

Nucl Med Biol. 2006 Oct;33(7):847-54.PMID: 17045164 [PubMed - indexed for MEDLINE]Related articles

The PPAR regulatory system in cardiac physiology and disease.

Finck BN.

Cardiovasc Res. 2007 Jan 15;73(2):269-77. Epub 2006 Sep 1. Review.PMID: 17010956 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway.

Finck BN, Gropler MC, Chen Z, Leone TC, Croce MA, Harris TE, Lawrence JC Jr, Kelly DP.

Cell Metab. 2006 Sep;4(3):199-210.PMID: 16950137 [PubMed - indexed for MEDLINE]Related articles

Diminished hepatic gluconeogenesis via defects in tricarboxylic acid cycle flux in peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha)-deficient mice.

Burgess SC, Leone TC, Wende AR, Croce MA, Chen Z, Sherry AD, Malloy CR, Finck BN.

J Biol Chem. 2006 Jul 14;281(28):19000-8. Epub 2006 May 2.PMID: 16670093 [PubMed - indexed for MEDLINE]Related articlesFree article

PGC-1 coactivators: inducible regulators of energy metabolism in health and disease.

Finck BN, Kelly DP.

J Clin Invest. 2006 Mar;116(3):615-22. Review.PMID: 16511594 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of PPARalpha on cardiac glucose metabolism: a transcriptional equivalent of the glucose-fatty acid cycle?

Finck BN.

Expert Rev Cardiovasc Ther. 2006 Mar;4(2):161-71. Review.PMID: 16509812 [PubMed - indexed for MEDLINE]Related articles

Chronic activation of PPARalpha is detrimental to cardiac recovery after ischemia.

Sambandam N, Morabito D, Wagg C, Finck BN, Kelly DP, Lopaschuk GD.

Am J Physiol Heart Circ Physiol. 2006 Jan;290(1):H87-95. Epub 2005 Sep 9.PMID: 16155108 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardiac-specific overexpression of peroxisome proliferator-activated receptor-alpha causes insulin resistance in heart and liver.

Park SY, Cho YR, Finck BN, Kim HJ, Higashimori T, Hong EG, Lee MK, Danton C, Deshmukh S, Cline GW, Wu JJ, Bennett AM, Rothermel B, Kalinowski A, Russell KS, Kim YB, Kelly DP, Kim JK.

Diabetes. 2005 Sep;54(9):2514-24.PMID: 16123338 [PubMed - indexed for MEDLINE]Related articlesFree article

A potential link between muscle peroxisome proliferator- activated receptor-alpha signaling and obesity-related diabetes.

Finck BN, Bernal-Mizrachi C, Han DH, Coleman T, Sambandam N, LaRiviere LL, Holloszy JO, Semenkovich CF, Kelly DP.

Cell Metab. 2005 Feb;1(2):133-44.PMID: 16054054 [PubMed - indexed for MEDLINE]Related articles

PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis.

Leone TC, Lehman JJ, Finck BN, Schaeffer PJ, Wende AR, Boudina S, Courtois M, Wozniak DF, Sambandam N, Bernal-Mizrachi C, Chen Z, Holloszy JO, Medeiros DM, Schmidt RE, Saffitz JE, Abel ED, Semenkovich CF, Kelly DP.

PLoS Biol. 2005 Apr;3(4):e101. Epub 2005 Mar 15.PMID: 15760270 [PubMed - indexed for MEDLINE]Related articlesFree article

Mouse models of mitochondrial dysfunction and heart failure.

Russell LK, Finck BN, Kelly DP.

J Mol Cell Cardiol. 2005 Jan;38(1):81-91. Epub 2004 Dec 8. Review.PMID: 15623424 [PubMed - indexed for MEDLINE]Related articles

G-protein signaling participates in the development of diabetic cardiomyopathy.

Harris IS, Treskov I, Rowley MW, Heximer S, Kaltenbronn K, Finck BN, Gross RW, Kelly DP, Blumer KJ, Muslin AJ.

Diabetes. 2004 Dec;53(12):3082-90.PMID: 15561937 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of the peroxisome proliferator-activated receptor alpha pathway in pathological remodeling of the diabetic heart.

Finck BN.

Curr Opin Clin Nutr Metab Care. 2004 Jul;7(4):391-6. Review.PMID: 15192440 [PubMed - indexed for MEDLINE]Related articles

Regulatory networks controlling mitochondrial energy production in the developing, hypertrophied, and diabetic heart.

Finck BN, Lehman JJ, Barger PM, Kelly DP.

Cold Spring Harb Symp Quant Biol. 2002;67:371-82. Review. No abstract available. PMID: 12858562 [PubMed - indexed for MEDLINE]Related articles

Dexamethasone induction of hypertension and diabetes is PPAR-alpha dependent in LDL receptor-null mice.

Bernal-Mizrachi C, Weng S, Feng C, Finck BN, Knutsen RH, Leone TC, Coleman T, Mecham RP, Kelly DP, Semenkovich CF.

Nat Med. 2003 Aug;9(8):1069-75. Epub 2003 Jul 6.PMID: 12847522 [PubMed - indexed for MEDLINE]Related articles

A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content.

Finck BN, Han X, Courtois M, Aimond F, Nerbonne JM, Kovacs A, Gross RW, Kelly DP.

Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1226-31. Epub 2003 Jan 27.PMID: 12552126 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator-activated receptor alpha (PPARalpha) signaling in the gene regulatory control of energy metabolism in the normal and diseased heart.

Finck BN, Kelly DP.

J Mol Cell Cardiol. 2002 Oct;34(10):1249-57. Review.PMID: 12425323 [PubMed - indexed for MEDLINE]Related articles

Anti-inflammatory agents inhibit the induction of leptin by tumor necrosis factor-alpha.

Finck BN, Johnson RW.

Am J Physiol Regul Integr Comp Physiol. 2002 May;282(5):R1429-35.PMID: 11959686 [PubMed - indexed for MEDLINE]Related articles

The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus.

Finck BN, Lehman JJ, Leone TC, Welch MJ, Bennett MJ, Kovacs A, Han X, Gross RW, Kozak R, Lopaschuk GD, Kelly DP.

J Clin Invest. 2002 Jan;109(1):121-30.PMID: 11781357 [PubMed - indexed for MEDLINE]Related articlesFree article

Tumor necrosis factor-alpha regulates secretion of the adipocyte-derived cytokine, leptin.

Finck BN, Johnson RW.

Microsc Res Tech. 2000 Aug 1;50(3):209-15. Review.PMID: 10891886 [PubMed - indexed for MEDLINE]Related articles

Interleukin (IL)-10 inhibits IL-6 production in microglia by preventing activation of NF-kappaB.

Heyen JR, Ye S, Finck BN, Johnson RW.

Brain Res Mol Brain Res. 2000 Apr 14;77(1):138-47.PMID: 10814840 [PubMed - indexed for MEDLINE]Related articles

Tumor necrosis factor (TNF)-alpha induces leptin production through the p55 TNF receptor.

Finck BN, Johnson RW.

Am J Physiol Regul Integr Comp Physiol. 2000 Feb;278(2):R537-43.PMID: 10666158 [PubMed - indexed for MEDLINE]Related articles

Intracerebroventricular injection of lipopolysaccharide increases plasma leptin levels.

Finck BN, Johnson RW.

Neuroreport. 1999 Jan 18;10(1):153-6.PMID: 10094153 [PubMed - indexed for MEDLINE]Related articles

In vivo and in vitro evidence for the involvement of tumor necrosis factor-alpha in the induction of leptin by lipopolysaccharide.

Finck BN, Kelley KW, Dantzer R, Johnson RW.

Endocrinology. 1998 May;139(5):2278-83.PMID: 9564834 [PubMed - indexed for MEDLINE]Related articlesFree article

Anorexia, weight loss and increased plasma interleukin-6 caused by chronic intracerebroventricular infusion of interleukin-1beta in the rat.

Finck BN, Johnson RW.

Brain Res. 1997 Jul 4;761(2):333-7.PMID: 9252034 [PubMed - indexed for MEDLINE]Related articles

Time course of increased plasma cytokines, cortisol, and urea nitrogen in pigs following intraperitoneal injection of lipopolysaccharide.

Webel DM, Finck BN, Baker DH, Johnson RW.

J Anim Sci. 1997 Jun;75(6):1514-20.PMID: 9250511 [PubMed - indexed for MEDLINE]Related articlesFree article

Central lipopolysaccharide elevates plasma IL-6 concentration by an alpha-adrenoreceptor-mediated mechanism.

Finck BN, Dantzer R, Kelley KW, Woods JA, Johnson RW.

Am J Physiol. 1997 Jun;272(6 Pt 2):R1880-7.PMID: 9227603 [PubMed - indexed for MEDLINE]Related articles

Coincidental changes in behavior and plasma cortisol in unrestrained pigs after intracerebroventricular injection of tumor necrosis factor-alpha.

Warren EJ, Finck BN, Arkins S, Kelley KW, Scamurra RW, Murtaugh MP, Johnson RW.

Endocrinology. 1997 Jun;138(6):2365-71.PMID: 9165024 [PubMed - indexed for MEDLINE]Related articlesFree article