PubMed

Mitochondrial DNA (mtDNA) Biogenesis: Visualization and Duel Incorporation of BrdU and EdU Into Newly Synthesized mtDNA In Vitro.

Lentz SI, Edwards JL, Backus C, McLean LL, Haines KM, Feldman EL.

J Histochem Cytochem. 2009 Nov 3. [Epub ahead of print]PMID: 19875847 [PubMed - as supplied by publisher]Related articlesFree article

Diabetes regulates mitochondrial biogenesis and fission in mouse neurons.

Edwards JL, Quattrini A, Lentz SI, Figueroa-Romero C, Cerri F, Backus C, Hong Y, Feldman EL.

Diabetologia. 2009 Oct 22. [Epub ahead of print]PMID: 19847394 [PubMed - as supplied by publisher]Related articles

Increased tau phosphorylation and cleavage in mouse models of type 1 and type 2 diabetes.

Kim B, Backus C, Oh S, Hayes JM, Feldman EL.

Endocrinology. 2009 Dec;150(12):5294-301. Epub 2009 Oct 9.PMID: 19819959 [PubMed - in process]Related articles

Nerve growth factor mediates mechanical allodynia in a mouse model of type 2 diabetes.

Cheng HT, Dauch JR, Hayes JM, Hong Y, Feldman EL.

J Neuropathol Exp Neurol. 2009 Nov;68(11):1229-43.PMID: 19816194 [PubMed - in process]Related articles

Neuroprotection using gene therapy to induce vascular endothelial growth factor-A expression.

Sakowski SA, Heavener SB, Lunn JS, Fung K, Oh SS, Spratt SK, Hogikyan ND, Feldman EL.

Gene Ther. 2009 Nov;16(11):1292-9. Epub 2009 Sep 3.PMID: 19727131 [PubMed - in process]Related articles

Vascular endothelial growth factor prevents G93A-SOD1-induced motor neuron degeneration.

Lunn JS, Sakowski SA, Kim B, Rosenberg AA, Feldman EL.

Dev Neurobiol. 2009 Nov;69(13):871-84.PMID: 19672955 [PubMed - in process]Related articles

SUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycle.

Figueroa-Romero C, Iñiguez-Lluhí JA, Stadler J, Chang CR, Arnoult D, Keller PJ, Hong Y, Blackstone C, Feldman EL.

FASEB J. 2009 Nov;23(11):3917-27. Epub 2009 Jul 28.PMID: 19638400 [PubMed - in process]Related articles

Patterning N-type and S-type neuroblastoma cells with Pluronic F108 and ECM proteins.

Corey JM, Gertz CC, Sutton TJ, Chen Q, Mycek KB, Wang BS, Martin AA, Johnson SL, Feldman EL.

J Biomed Mater Res A. 2009 Jul 16. [Epub ahead of print]PMID: 19609877 [PubMed - as supplied by publisher]Related articles

Dyslipidemia-induced neuropathy in mice: the role of oxLDL/LOX-1.

Vincent AM, Hayes JM, McLean LL, Vivekanandan-Giri A, Pennathur S, Feldman EL.

Diabetes. 2009 Oct;58(10):2376-85. Epub 2009 Jul 10.PMID: 19592619 [PubMed - indexed for MEDLINE]Related articles

Effects of prior intensive insulin therapy on cardiac autonomic nervous system function in type 1 diabetes mellitus: the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications study (DCCT/EDIC).

Pop-Busui R, Low PA, Waberski BH, Martin CL, Albers JW, Feldman EL, Sommer C, Cleary PA, Lachin JM, Herman WH; DCCT/EDIC Research Group.

Circulation. 2009 Jun 9;119(22):2886-93. Epub 2009 May 26.PMID: 19470886 [PubMed - in process]Related articles

Elevated triglycerides correlate with progression of diabetic neuropathy.

Wiggin TD, Sullivan KA, Pop-Busui R, Amato A, Sima AA, Feldman EL.

Diabetes. 2009 Jul;58(7):1634-40. Epub 2009 May 1.PMID: 19411614 [PubMed - indexed for MEDLINE]Related articlesFree article

Computational methods for predicting sites of functionally important dynamics.

Schuyler AD, Carlson HA, Feldman EL.

J Phys Chem B. 2009 May 14;113(19):6613-22.PMID: 19378962 [PubMed - indexed for MEDLINE]Related articles

Stem cells: comprehensive treatments for amyotrophic lateral sclerosis in conjunction with growth factor delivery.

Lunn JS, Hefferan MP, Marsala M, Feldman EL.

Growth Factors. 2009 Jun;27(3):133-40. Review.PMID: 19294549 [PubMed - indexed for MEDLINE]Related articles

Hydrogen peroxide-induced Akt phosphorylation regulates Bax activation.

Sadidi M, Lentz SI, Feldman EL.

Biochimie. 2009 May;91(5):577-85. Epub 2009 Feb 6.PMID: 19278624 [PubMed - indexed for MEDLINE]Related articles

Reliability of quantitative sudomotor axon reflex testing and quantitative sensory testing in neuropathy of impaired glucose regulation.

Peltier A, Smith AG, Russell JW, Sheikh K, Bixby B, Howard J, Goldstein J, Song Y, Wang L, Feldman EL, Singleton JR.

Muscle Nerve. 2009 Apr;39(4):529-35.PMID: 19260066 [PubMed - indexed for MEDLINE]Related articles

Insulin receptor substrate (IRS)-2, not IRS-1, protects human neuroblastoma cells against apoptosis.

Kim B, Feldman EL.

Apoptosis. 2009 May;14(5):665-73.PMID: 19259821 [PubMed - indexed for MEDLINE]Related articles

Disorders of cranial nerves IX and X.

Erman AB, Kejner AE, Hogikyan ND, Feldman EL.

Semin Neurol. 2009 Feb;29(1):85-92. Epub 2009 Feb 12. Review.PMID: 19214937 [PubMed - indexed for MEDLINE]Related articles

Loss of myotubularin function results in T-tubule disorganization in zebrafish and human myotubular myopathy.

Dowling JJ, Vreede AP, Low SE, Gibbs EM, Kuwada JY, Bonnemann CG, Feldman EL.

PLoS Genet. 2009 Feb;5(2):e1000372. Epub 2009 Feb 6.PMID: 19197364 [PubMed - indexed for MEDLINE]Related articlesFree article

SciMiner: web-based literature mining tool for target identification and functional enrichment analysis.

Hur J, Schuyler AD, States DJ, Feldman EL.

Bioinformatics. 2009 Mar 15;25(6):838-40. Epub 2009 Feb 2.PMID: 19188191 [PubMed - indexed for MEDLINE]Related articlesFree article

Intraspinal cord delivery of IGF-I mediated by adeno-associated virus 2 is neuroprotective in a rat model of familial ALS.

Franz CK, Federici T, Yang J, Backus C, Oh SS, Teng Q, Carlton E, Bishop KM, Gasmi M, Bartus RT, Feldman EL, Boulis NM.

Neurobiol Dis. 2009 Mar;33(3):473-81. Epub 2008 Dec 24.PMID: 19135533 [PubMed - indexed for MEDLINE]Related articles

Sensory Neurons and Schwann Cells Respond to Oxidative Stress by Increasing Antioxidant Defense Mechanisms.

Vincent AM, Kato K, McLean LL, Soules ME, Feldman EL.

Antioxid Redox Signal. 2008 Dec 11. [Epub ahead of print]PMID: 19072199 [PubMed - as supplied by publisher]Related articles

The Utah Early Neuropathy Scale: a sensitive clinical scale for early sensory predominant neuropathy.

Singleton JR, Bixby B, Russell JW, Feldman EL, Peltier A, Goldstein J, Howard J, Smith AG.

J Peripher Nerv Syst. 2008 Sep;13(3):218-27.PMID: 18844788 [PubMed - indexed for MEDLINE]Related articles

Insulin-like growth factors in the peripheral nervous system.

Sullivan KA, Kim B, Feldman EL.

Endocrinology. 2008 Dec;149(12):5963-71. Epub 2008 Aug 21. Review.PMID: 18719018 [PubMed - indexed for MEDLINE]Related articles

Mechanisms of disease: the oxidative stress theory of diabetic neuropathy.

Figueroa-Romero C, Sadidi M, Feldman EL.

Rev Endocr Metab Disord. 2008 Dec;9(4):301-14. Review.PMID: 18709457 [PubMed - indexed for MEDLINE]Related articles

Rosiglitazone reduces renal and plasma markers of oxidative injury and reverses urinary metabolite abnormalities in the amelioration of diabetic nephropathy.

Zhang H, Saha J, Byun J, Schin M, Lorenz M, Kennedy RT, Kretzler M, Feldman EL, Pennathur S, Brosius FC 3rd.

Am J Physiol Renal Physiol. 2008 Oct;295(4):F1071-81. Epub 2008 Jul 30.PMID: 18667486 [PubMed - indexed for MEDLINE]Related articlesFree article

Diabetic neuropathy: mechanisms to management.

Edwards JL, Vincent AM, Cheng HT, Feldman EL.

Pharmacol Ther. 2008 Oct;120(1):1-34. Epub 2008 Jun 13. Review.PMID: 18616962 [PubMed - indexed for MEDLINE]Related articles

Kindlin-2 is required for myocyte elongation and is essential for myogenesis.

Dowling JJ, Vreede AP, Kim S, Golden J, Feldman EL.

BMC Cell Biol. 2008 Jul 8;9:36.PMID: 18611274 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-like growth factor-I for the treatment of amyotrophic lateral sclerosis.

Sakowski SA, Schuyler AD, Feldman EL.

Amyotroph Lateral Scler. 2009 Apr;10(2):63-73. Review.PMID: 18608100 [PubMed - indexed for MEDLINE]Related articles

Rosiglitazone treatment reduces diabetic neuropathy in streptozotocin-treated DBA/2J mice.

Wiggin TD, Kretzler M, Pennathur S, Sullivan KA, Brosius FC, Feldman EL.

Endocrinology. 2008 Oct;149(10):4928-37. Epub 2008 Jun 26.PMID: 18583417 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidative injury and neuropathy in diabetes and impaired glucose tolerance.

Russell JW, Berent-Spillson A, Vincent AM, Freimann CL, Sullivan KA, Feldman EL.

Neurobiol Dis. 2008 Jun;30(3):420-9. Epub 2008 Mar 15.PMID: 18424057 [PubMed - indexed for MEDLINE]Related articlesFree article

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) meeting summary: Advances toward measuring diabetic retinopathy and neuropathy: from the bench to the clinic and back again (April 4-5, 2007, Baltimore, Maryland).

Kern TS, Berkowitz BA, Feldman EL.

J Diabetes Complications. 2009 May-Jun;23(3):219-23. Epub 2008 Apr 16.PMID: 18413183 [PubMed - indexed for MEDLINE]Related articles

The design of electrospun PLLA nanofiber scaffolds compatible with serum-free growth of primary motor and sensory neurons.

Corey JM, Gertz CC, Wang BS, Birrell LK, Johnson SL, Martin DC, Feldman EL.

Acta Biomater. 2008 Jul;4(4):863-75. Epub 2008 Mar 12.PMID: 18396117 [PubMed - indexed for MEDLINE]Related articles

Abnormal muscle spindle innervation and large-fiber neuropathy in diabetic mice.

Muller KA, Ryals JM, Feldman EL, Wright DE.

Diabetes. 2008 Jun;57(6):1693-701. Epub 2008 Mar 24.PMID: 18362211 [PubMed - indexed for MEDLINE]Related articlesFree article

National Institute of Neurological Disorders and Stroke (NINDS): advances in understanding and treating neuropathy, 24-25 October 2006; Bethesda, Maryland.

Feldman EL, Cornblath DR, Porter J, Dworkin R, Scherer S; Attendees of the NIH Peripheral Neuropathy Conference.

J Peripher Nerv Syst. 2008 Mar;13(1):1-6.PMID: 18346227 [PubMed - indexed for MEDLINE]Related articlesFree article

Membrane traffic and muscle: lessons from human disease.

Dowling JJ, Gibbs EM, Feldman EL.

Traffic. 2008 Jul;9(7):1035-43. Epub 2008 Feb 4. Review.PMID: 18266915 [PubMed - indexed for MEDLINE]Related articles

The antioxidant response as a drug target in diabetic neuropathy.

Vincent AM, Edwards JL, Sadidi M, Feldman EL.

Curr Drug Targets. 2008 Jan;9(1):94-100. Review.PMID: 18220717 [PubMed - indexed for MEDLINE]Related articles

Criteria for creating and assessing mouse models of diabetic neuropathy.

Sullivan KA, Lentz SI, Roberts JL Jr, Feldman EL.

Curr Drug Targets. 2008 Jan;9(1):3-13. Review.PMID: 18220709 [PubMed - indexed for MEDLINE]Related articles

Diabetic neuropathy.

Feldman EL.

Curr Drug Targets. 2008 Jan;9(1):1-2. No abstract available. PMID: 18220708 [PubMed - indexed for MEDLINE]Related articles

Strategic approaches to developing drug treatments for ALS.

Vincent AM, Sakowski SA, Schuyler A, Feldman EL.

Drug Discov Today. 2008 Jan;13(1-2):67-72. Epub 2007 Nov 26. Review.PMID: 18190866 [PubMed - indexed for MEDLINE]Related articlesFree article

Kindlin-2 is an essential component of intercalated discs and is required for vertebrate cardiac structure and function.

Dowling JJ, Gibbs E, Russell M, Goldman D, Minarcik J, Golden JA, Feldman EL.

Circ Res. 2008 Feb 29;102(4):423-31. Epub 2008 Jan 3.PMID: 18174465 [PubMed - indexed for MEDLINE]Related articlesFree article

Can drug screening lead to candidate therapies for testing in diabetic neuropathy?

Vincent AM, Feldman EL.

Antioxid Redox Signal. 2008 Feb;10(2):387-93.PMID: 17961065 [PubMed - indexed for MEDLINE]Related articles

SOD2 protects neurons from injury in cell culture and animal models of diabetic neuropathy.

Vincent AM, Russell JW, Sullivan KA, Backus C, Hayes JM, McLean LL, Feldman EL.

Exp Neurol. 2007 Dec;208(2):216-27. Epub 2007 Aug 3.PMID: 17927981 [PubMed - indexed for MEDLINE]Related articlesFree article

Mouse models of diabetic neuropathy.

Sullivan KA, Hayes JM, Wiggin TD, Backus C, Su Oh S, Lentz SI, Brosius F 3rd, Feldman EL.

Neurobiol Dis. 2007 Dec;28(3):276-85. Epub 2007 Jul 31.PMID: 17804249 [PubMed - indexed for MEDLINE]Related articles

Dysfunction of the recurrent laryngeal nerve and the potential of gene therapy.

Heavner SB, Rubin AD, Fung K, Old M, Hogikyan ND, Feldman EL.

Ann Otol Rhinol Laryngol. 2007 Jun;116(6):441-8. Review.PMID: 17672247 [PubMed - indexed for MEDLINE]Related articles

Development and characterisation of an experimental recurrent laryngeal nerve injury model for the study of viral gene therapy.

Fung K, Hogikyan ND, Heavner SB, Ekbom D, Feldman EL.

J Laryngol Otol. 2008 May;122(5):500-5. Epub 2007 Jun 25.PMID: 17592655 [PubMed - indexed for MEDLINE]Related articles

Aligned electrospun nanofibers specify the direction of dorsal root ganglia neurite growth.

Corey JM, Lin DY, Mycek KB, Chen Q, Samuel S, Feldman EL, Martin DC.

J Biomed Mater Res A. 2007 Dec 1;83(3):636-45.PMID: 17508416 [PubMed - indexed for MEDLINE]Related articles

Diabetic neuropathies.

Little AA, Edwards JL, Feldman EL.

Pract Neurol. 2007 Apr;7(2):82-92. Review. No abstract available. PMID: 17430872 [PubMed - indexed for MEDLINE]Related articles

Receptor for advanced glycation end products activation injures primary sensory neurons via oxidative stress.

Vincent AM, Perrone L, Sullivan KA, Backus C, Sastry AM, Lastoskie C, Feldman EL.

Endocrinology. 2007 Feb;148(2):548-58. Epub 2006 Nov 9.PMID: 17095586 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanisms of disease: mitochondria as new therapeutic targets in diabetic neuropathy.

Leinninger GM, Edwards JL, Lipshaw MJ, Feldman EL.

Nat Clin Pract Neurol. 2006 Nov;2(11):620-8. Review.PMID: 17057749 [PubMed - indexed for MEDLINE]Related articles

Biomedical research: a culture in crisis?

Feldman EL.

Nat Clin Pract Neurol. 2005 Dec;1(2):61. No abstract available. PMID: 16932493 [PubMed - indexed for MEDLINE]Related articles