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Erratum to: Stearoyl CoA desaturase 1 is elevated in obesity but protects against fatty acid-induced skeletal muscle insulin resistance in vitro.

Pinnamaneni SK, Southgate RJ, Febbraio MA, Watt MJ.

Diabetologia. 2009 Oct 29. [Epub ahead of print] No abstract available. PMID: 19865807 [PubMed - as supplied by publisher]Related articles

Reactive oxygen species enhance insulin sensitivity.

Loh K, Deng H, Fukushima A, Cai X, Boivin B, Galic S, Bruce C, Shields BJ, Skiba B, Ooms LM, Stepto N, Wu B, Mitchell CA, Tonks NK, Watt MJ, Febbraio MA, Crack PJ, Andrikopoulos S, Tiganis T.

Cell Metab. 2009 Oct;10(4):260-72.PMID: 19808019 [PubMed - in process]Related articles

Role of exercise-induced brain-derived neurotrophic factor production in the regulation of energy homeostasis in mammals.

Pedersen BK, Pedersen M, Krabbe KS, Bruunsgaard H, Matthews VB, Febbraio MA.

Exp Physiol. 2009 Dec;94(12):1153-60. Epub 2009 Sep 11.PMID: 19748969 [PubMed - in process]Related articles

Brain-derived neurotrophic factor is produced by skeletal muscle cells in response to contraction and enhances fat oxidation via activation of AMP-activated protein kinase.

Matthews VB, Aström MB, Chan MH, Bruce CR, Krabbe KS, Prelovsek O, Akerström T, Yfanti C, Broholm C, Mortensen OH, Penkowa M, Hojman P, Zankari A, Watt MJ, Bruunsgaard H, Pedersen BK, Febbraio MA.

Diabetologia. 2009 Jul;52(7):1409-18. Epub 2009 Apr 22.PMID: 19387610 [PubMed - indexed for MEDLINE]Related articles

High-density lipoprotein modulates glucose metabolism in patients with type 2 diabetes mellitus.

Drew BG, Duffy SJ, Formosa MF, Natoli AK, Henstridge DC, Penfold SA, Thomas WG, Mukhamedova N, de Courten B, Forbes JM, Yap FY, Kaye DM, van Hall G, Febbraio MA, Kemp BE, Sviridov D, Steinberg GR, Kingwell BA.

Circulation. 2009 Apr 21;119(15):2103-11. Epub 2009 Apr 6.PMID: 19349317 [PubMed - indexed for MEDLINE]Related articles

Site-specific antiatherogenic effect of the antioxidant ebselen in the diabetic apolipoprotein E-deficient mouse.

Chew P, Yuen DY, Koh P, Stefanovic N, Febbraio MA, Kola I, Cooper ME, de Haan JB.

Arterioscler Thromb Vasc Biol. 2009 Jun;29(6):823-30. Epub 2009 Mar 26.PMID: 19325139 [PubMed - indexed for MEDLINE]Related articles

Cytokine Regulation of AMPK signalling.

Steinberg GR, Watt MJ, Febbraio MA.

Front Biosci. 2009 Jan 1;14:1902-16. Review.PMID: 19273172 [PubMed - indexed for MEDLINE]Related articles

Examination of 'lipotoxicity' in skeletal muscle of high-fat fed and ob/ob mice.

Turpin SM, Ryall JG, Southgate R, Darby I, Hevener AL, Febbraio MA, Kemp BE, Lynch GS, Watt MJ.

J Physiol. 2009 Apr 1;587(Pt 7):1593-605. Epub 2009 Feb 9.PMID: 19204053 [PubMed - indexed for MEDLINE]Related articles

Interleukin-6 attenuates insulin-mediated increases in endothelial cell signaling but augments skeletal muscle insulin action via differential effects on tumor necrosis factor-alpha expression.

Yuen DY, Dwyer RM, Matthews VB, Zhang L, Drew BG, Neill B, Kingwell BA, Clark MG, Rattigan S, Febbraio MA.

Diabetes. 2009 May;58(5):1086-95. Epub 2009 Feb 2.PMID: 19188427 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance.

Bruce CR, Hoy AJ, Turner N, Watt MJ, Allen TL, Carpenter K, Cooney GJ, Febbraio MA, Kraegen EW.

Diabetes. 2009 Mar;58(3):550-8. Epub 2008 Dec 10.PMID: 19073774 [PubMed - indexed for MEDLINE]Related articlesFree article

Skeletal muscle: not simply an organ for locomotion and energy storage.

Lancaster GI, Febbraio MA.

J Physiol. 2009 Feb 1;587(Pt 3):509-10. Epub 2008 Dec 1. No abstract available. PMID: 19047198 [PubMed - indexed for MEDLINE]Related articles

Alpha2-AMPK activity is not essential for an increase in fatty acid oxidation during low-intensity exercise.

Miura S, Kai Y, Kamei Y, Bruce CR, Kubota N, Febbraio MA, Kadowaki T, Ezaki O.

Am J Physiol Endocrinol Metab. 2009 Jan;296(1):E47-55. Epub 2008 Oct 21.PMID: 18940938 [PubMed - indexed for MEDLINE]Related articles

Muscle as an endocrine organ: focus on muscle-derived interleukin-6.

Pedersen BK, Febbraio MA.

Physiol Rev. 2008 Oct;88(4):1379-406. Review.PMID: 18923185 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidative stress-induced insulin resistance in skeletal muscle cells is ameliorated by gamma-tocopherol treatment.

Singh I, Carey AL, Watson N, Febbraio MA, Hawley JA.

Eur J Nutr. 2008 Oct;47(7):387-92. Epub 2008 Sep 18.PMID: 18807106 [PubMed - indexed for MEDLINE]Related articles

Prolonged interleukin-6 administration enhances glucose tolerance and increases skeletal muscle PPARalpha and UCP2 expression in rats.

Holmes AG, Mesa JL, Neill BA, Chung J, Carey AL, Steinberg GR, Kemp BE, Southgate RJ, Lancaster GI, Bruce CR, Watt MJ, Febbraio MA.

J Endocrinol. 2008 Aug;198(2):367-74. Epub 2008 Jun 3. Erratum in: J Endocrinol. 2008 Oct;199(1):147. PMID: 18523033 [PubMed - indexed for MEDLINE]Related articlesFree article

HSP72 protects against obesity-induced insulin resistance.

Chung J, Nguyen AK, Henstridge DC, Holmes AG, Chan MH, Mesa JL, Lancaster GI, Southgate RJ, Bruce CR, Duffy SJ, Horvath I, Mestril R, Watt MJ, Hooper PL, Kingwell BA, Vigh L, Hevener A, Febbraio MA.

Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1739-44. Epub 2008 Jan 25.PMID: 18223156 [PubMed - indexed for MEDLINE]Related articlesFree article

CNTF: a target therapeutic for obesity-related metabolic disease?

Matthews VB, Febbraio MA.

J Mol Med. 2008 Apr;86(4):353-61. Epub 2008 Jan 22. Review.PMID: 18210031 [PubMed - indexed for MEDLINE]Related articles

Effect of high-frequency resistance exercise on adaptive responses in skeletal muscle.

Coffey VG, Reeder DW, Lancaster GI, Yeo WK, Febbraio MA, Yaspelkis BB 3rd, Hawley JA.

Med Sci Sports Exerc. 2007 Dec;39(12):2135-44.PMID: 18046184 [PubMed - indexed for MEDLINE]Related articles

It's what you do with the fat that matters!

Bruce CR, Febbraio MA.

Nat Med. 2007 Oct;13(10):1137-8. No abstract available. PMID: 17917654 [PubMed - indexed for MEDLINE]Related articles

Hepatic lactate uptake versus leg lactate output during exercise in humans.

Nielsen HB, Febbraio MA, Ott P, Krustrup P, Secher NH.

J Appl Physiol. 2007 Oct;103(4):1227-33. Epub 2007 Jul 26.PMID: 17656631 [PubMed - indexed for MEDLINE]Related articlesFree article

Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones.

Hevener AL, Olefsky JM, Reichart D, Nguyen MT, Bandyopadyhay G, Leung HY, Watt MJ, Benner C, Febbraio MA, Nguyen AK, Folian B, Subramaniam S, Gonzalez FJ, Glass CK, Ricote M.

J Clin Invest. 2007 Jun;117(6):1658-69. Epub 2007 May 24.PMID: 17525798 [PubMed - indexed for MEDLINE]Related articlesFree article

FOXO1 regulates the expression of 4E-BP1 and inhibits mTOR signaling in mammalian skeletal muscle.

Southgate RJ, Neill B, Prelovsek O, El-Osta A, Kamei Y, Miura S, Ezaki O, McLoughlin TJ, Zhang W, Unterman TG, Febbraio MA.

J Biol Chem. 2007 Jul 20;282(29):21176-86. Epub 2007 May 17. Retraction in: J Biol Chem. 2009 Jul 24;284(30):20440. PMID: 17510058 [PubMed - indexed for MEDLINE]Related articlesFree article

Exercise and inflammation.

Febbraio MA.

J Appl Physiol. 2007 Jul;103(1):376-7. Epub 2007 Apr 19. No abstract available. PMID: 17446409 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue-specific effects of rosiglitazone and exercise in the treatment of lipid-induced insulin resistance.

Lessard SJ, Rivas DA, Chen ZP, Bonen A, Febbraio MA, Reeder DW, Kemp BE, Yaspelkis BB 3rd, Hawley JA.

Diabetes. 2007 Jul;56(7):1856-64. Epub 2007 Apr 17.PMID: 17440174 [PubMed - indexed for MEDLINE]Related articlesFree article

gp130 receptor ligands as potential therapeutic targets for obesity.

Febbraio MA.

J Clin Invest. 2007 Apr;117(4):841-9.PMID: 17404609 [PubMed - indexed for MEDLINE]Related articlesFree article

Tumor necrosis factor alpha-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling.

Steinberg GR, Michell BJ, van Denderen BJ, Watt MJ, Carey AL, Fam BC, Andrikopoulos S, Proietto J, Görgün CZ, Carling D, Hotamisligil GS, Febbraio MA, Kay TW, Kemp BE.

Cell Metab. 2006 Dec;4(6):465-74.PMID: 17141630 [PubMed - indexed for MEDLINE]Related articles

Point: Interleukin-6 does have a beneficial role in insulin sensitivity and glucose homeostasis.

Pedersen BK, Febbraio MA.

J Appl Physiol. 2007 Feb;102(2):814-6. Epub 2006 Oct 26. No abstract available. PMID: 17068210 [PubMed - indexed for MEDLINE]Related articlesFree article

Stearoyl CoA desaturase 1 is elevated in obesity but protects against fatty acid-induced skeletal muscle insulin resistance in vitro.

Pinnamaneni SK, Southgate RJ, Febbraio MA, Watt MJ.

Diabetologia. 2006 Dec;49(12):3027-37. Epub 2006 Oct 11.PMID: 17033839 [PubMed - indexed for MEDLINE]Related articles

Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase.

Carey AL, Steinberg GR, Macaulay SL, Thomas WG, Holmes AG, Ramm G, Prelovsek O, Hohnen-Behrens C, Watt MJ, James DE, Kemp BE, Pedersen BK, Febbraio MA.

Diabetes. 2006 Oct;55(10):2688-97.PMID: 17003332 [PubMed - indexed for MEDLINE]Related articlesFree article

AMP-activated protein kinase--the fat controller of the energy railroad.

Steinberg GR, Macaulay SL, Febbraio MA, Kemp BE.

Can J Physiol Pharmacol. 2006 Jul;84(7):655-65. Review.PMID: 16998529 [PubMed - indexed for MEDLINE]Related articles

Apoptosis in skeletal muscle myotubes is induced by ceramides and is positively related to insulin resistance.

Turpin SM, Lancaster GI, Darby I, Febbraio MA, Watt MJ.

Am J Physiol Endocrinol Metab. 2006 Dec;291(6):E1341-50. Epub 2006 Jul 18.PMID: 16849630 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced glycogen availability is associated with increased AMPKalpha2 activity, nuclear AMPKalpha2 protein abundance, and GLUT4 mRNA expression in contracting human skeletal muscle.

Steinberg GR, Watt MJ, McGee SL, Chan S, Hargreaves M, Febbraio MA, Stapleton D, Kemp BE.

Appl Physiol Nutr Metab. 2006 Jun;31(3):302-12.PMID: 16770359 [PubMed - indexed for MEDLINE]Related articles

Ciliary neurotrophic factor suppresses hypothalamic AMP-kinase signaling in leptin-resistant obese mice.

Steinberg GR, Watt MJ, Fam BC, Proietto J, Andrikopoulos S, Allen AM, Febbraio MA, Kemp BE.

Endocrinology. 2006 Aug;147(8):3906-14. Epub 2006 May 4.PMID: 16675525 [PubMed - indexed for MEDLINE]Related articlesFree article

Fatty acids stimulate AMP-activated protein kinase and enhance fatty acid oxidation in L6 myotubes.

Watt MJ, Steinberg GR, Chen ZP, Kemp BE, Febbraio MA.

J Physiol. 2006 Jul 1;574(Pt 1):139-47. Epub 2006 Apr 27.PMID: 16644805 [PubMed - indexed for MEDLINE]Related articlesFree article

CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK.

Watt MJ, Dzamko N, Thomas WG, Rose-John S, Ernst M, Carling D, Kemp BE, Febbraio MA, Steinberg GR.

Nat Med. 2006 May;12(5):541-8. Epub 2006 Apr 9.PMID: 16604088 [PubMed - indexed for MEDLINE]Related articles

Discordant gene expression in skeletal muscle and adipose tissue of patients with type 2 diabetes: effect of interleukin-6 infusion.

Carey AL, Petersen EW, Bruce CR, Southgate RJ, Pilegaard H, Hawley JA, Pedersen BK, Febbraio MA.

Diabetologia. 2006 May;49(5):1000-7. Epub 2006 Mar 15.PMID: 16538490 [PubMed - indexed for MEDLINE]Related articles

Ciliary neurotrophic factor prevents acute lipid-induced insulin resistance by attenuating ceramide accumulation and phosphorylation of c-Jun N-terminal kinase in peripheral tissues.

Watt MJ, Hevener A, Lancaster GI, Febbraio MA.

Endocrinology. 2006 May;147(5):2077-85. Epub 2006 Jan 5.PMID: 16396984 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanisms of stress-induced cellular HSP72 release: implications for exercise-induced increases in extracellular HSP72.

Lancaster GI, Febbraio MA.

Exerc Immunol Rev. 2005;11:46-52. Review.PMID: 16385843 [PubMed - indexed for MEDLINE]Related articlesFree article

Vitamin E isoform-specific inhibition of the exercise-induced heat shock protein 72 expression in humans.

Fischer CP, Hiscock NJ, Basu S, Vessby B, Kallner A, Sjöberg LB, Febbraio MA, Pedersen BK.

J Appl Physiol. 2006 May;100(5):1679-87. Epub 2005 Dec 29.PMID: 16384840 [PubMed - indexed for MEDLINE]Related articlesFree article

Saturated, but not n-6 polyunsaturated, fatty acids induce insulin resistance: role of intramuscular accumulation of lipid metabolites.

Lee JS, Pinnamaneni SK, Eo SJ, Cho IH, Pyo JH, Kim CK, Sinclair AJ, Febbraio MA, Watt MJ.

J Appl Physiol. 2006 May;100(5):1467-74. Epub 2005 Dec 15.PMID: 16357064 [PubMed - indexed for MEDLINE]Related articlesFree article

PGC-1alpha gene expression is down-regulated by Akt- mediated phosphorylation and nuclear exclusion of FoxO1 in insulin-stimulated skeletal muscle.

Southgate RJ, Bruce CR, Carey AL, Steinberg GR, Walder K, Monks R, Watt MJ, Hawley JA, Birnbaum MJ, Febbraio MA.

FASEB J. 2005 Dec;19(14):2072-4. Epub 2005 Oct 3. Retraction in: FASEB J. 2009 Aug;23(8):2790. PMID: 16203862 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of HSL serine phosphorylation in skeletal muscle and adipose tissue.

Watt MJ, Holmes AG, Pinnamaneni SK, Garnham AP, Steinberg GR, Kemp BE, Febbraio MA.

Am J Physiol Endocrinol Metab. 2006 Mar;290(3):E500-8. Epub 2005 Sep 27. Erratum in: Am J Physiol Endocrinol Metab. 2009 Feb;296(2):E401. PMID: 16188906 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic rosiglitazone treatment restores AMPKalpha2 activity in insulin-resistant rat skeletal muscle.

Lessard SJ, Chen ZP, Watt MJ, Hashem M, Reid JJ, Febbraio MA, Kemp BE, Hawley JA.

Am J Physiol Endocrinol Metab. 2006 Feb;290(2):E251-7. Epub 2005 Aug 23.PMID: 16118254 [PubMed - indexed for MEDLINE]Related articlesFree article

Heat stress, cytokines, and the immune response to exercise.

Starkie RL, Hargreaves M, Rolland J, Febbraio MA.

Brain Behav Immun. 2005 Sep;19(5):404-12.PMID: 16061150 [PubMed - indexed for MEDLINE]Related articles

Contraction-induced myokine production and release: is skeletal muscle an endocrine organ?

Febbraio MA, Pedersen BK.

Exerc Sport Sci Rev. 2005 Jul;33(3):114-9. Review.PMID: 16006818 [PubMed - indexed for MEDLINE]Related articles

Skeletal muscle phenotype is associated with exercise tolerance in patients with peripheral arterial disease.

Askew CD, Green S, Walker PJ, Kerr GK, Green AA, Williams AD, Febbraio MA.

J Vasc Surg. 2005 May;41(5):802-7.PMID: 15886664 [PubMed - indexed for MEDLINE]Related articles

Exosome-dependent trafficking of HSP70: a novel secretory pathway for cellular stress proteins.

Lancaster GI, Febbraio MA.

J Biol Chem. 2005 Jun 17;280(24):23349-55. Epub 2005 Apr 12.PMID: 15826944 [PubMed - indexed for MEDLINE]Related articlesFree article

Recombinant human interleukin-6 infusion during low-intensity exercise does not enhance whole body lipolysis or fat oxidation in humans.

Hiscock N, Fischer CP, Sacchetti M, van Hall G, Febbraio MA, Pedersen BK.

Am J Physiol Endocrinol Metab. 2005 Jul;289(1):E2-7. Epub 2005 Mar 1.PMID: 15741245 [PubMed - indexed for MEDLINE]Related articlesFree article

Does the aging skeletal muscle maintain its endocrine function?

Pedersen M, Steensberg A, Keller C, Osada T, Zacho M, Saltin B, Febbraio MA, Pedersen BK.

Exerc Immunol Rev. 2004;10:42-55.PMID: 15633585 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose ingestion attenuates the exercise-induced increase in circulating heat shock protein 72 and heat shock protein 60 in humans.

Febbraio MA, Mesa JL, Chung J, Steensberg A, Keller C, Nielsen HB, Krustrup P, Ott P, Secher NH, Pedersen BK.

Cell Stress Chaperones. 2004 Winter;9(4):390-6.PMID: 15633297 [PubMed - indexed for MEDLINE]Related articlesFree article