PubMed

Loss of the metalloprotease ADAM9 leads to cone-rod dystrophy in humans and retinal degeneration in mice.

Parry DA, Toomes C, Bida L, Danciger M, Towns KV, McKibbin M, Jacobson SG, Logan CV, Ali M, Bond J, Chance R, Swendeman S, Daniele LL, Springell K, Adams M, Johnson CA, Booth AP, Jafri H, Rashid Y, Banin E, Strom TM, Farber DB, Sharon D, Blobel CP, Pugh EN Jr, Pierce EA, Inglehearn CF.

Am J Hum Genet. 2009 May;84(5):683-91. Epub 2009 Apr 30.PMID: 19409519 [PubMed - indexed for MEDLINE]Related articlesFree article

ZBED4, a BED-type zinc-finger protein in the cones of the human retina.

Saghizadeh M, Akhmedov NB, Yamashita CK, Gribanova Y, Theendakara V, Mendoza E, Nelson SF, Ljubimov AV, Farber DB.

Invest Ophthalmol Vis Sci. 2009 Aug;50(8):3580-8. Epub 2009 Apr 15.PMID: 19369242 [PubMed - indexed for MEDLINE]Related articles

Transfer of microRNAs by embryonic stem cell microvesicles.

Yuan A, Farber EL, Rapoport AL, Tejada D, Deniskin R, Akhmedov NB, Farber DB.

PLoS One. 2009;4(3):e4722. Epub 2009 Mar 6.PMID: 19266099 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulatory sequences in the 3' untranslated region of the human cGMP-phosphodiesterase beta-subunit gene.

Verardo MR, Viczian A, Piri N, Akhmedov NB, Knox BE, Farber DB.

Invest Ophthalmol Vis Sci. 2009 Jun;50(6):2591-8. Epub 2009 Feb 14.PMID: 19218616 [PubMed - indexed for MEDLINE]Related articlesFree article

Non-invasive gene transfer by iontophoresis for therapy of an inherited retinal degeneration.

Souied EH, Reid SN, Piri NI, Lerner LE, Nusinowitz S, Farber DB.

Exp Eye Res. 2008 Sep;87(3):168-75. Epub 2008 Apr 29.PMID: 18653181 [PubMed - indexed for MEDLINE]Related articlesFree article

Involvement of OA1, an intracellular GPCR, and G alpha i3, its binding protein, in melanosomal biogenesis and optic pathway formation.

Young A, Powelson EB, Whitney IE, Raven MA, Nusinowitz S, Jiang M, Birnbaumer L, Reese BE, Farber DB.

Invest Ophthalmol Vis Sci. 2008 Jul;49(7):3245-52. Epub 2008 Mar 31.PMID: 18378571 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification and characterization of genes expressed in cone photoreceptors.

Saghizadeh M, Akhmedov NB, Farber DB.

Adv Exp Med Biol. 2008;613:235-44. No abstract available. PMID: 18188950 [PubMed - indexed for MEDLINE]Related articles

Multidisciplinary management of advanced occlusal periodontitis: genioplasty for autogenous block bone grafts.

Farber DB, Chmar WE, Dzyak WR.

Compend Contin Educ Dent. 2007 Oct;28(10):564-8; quiz 569.PMID: 18018391 [PubMed - indexed for MEDLINE]Related articles

Evidence for retinal remodelling in retinitis pigmentosa caused by PDE6B mutation.

Jacobson SG, Sumaroka A, Aleman TS, Cideciyan AV, Danciger M, Farber DB.

Br J Ophthalmol. 2007 May;91(5):699-701. No abstract available. PMID: 17446517 [PubMed - indexed for MEDLINE]Related articles

Replication and refinement of linkage of posterior polymorphous corneal dystrophy to the posterior polymorphous corneal dystrophy 1 locus on chromosome 20.

Yellore VS, Papp JC, Sobel E, Khan MA, Rayner SA, Farber DB, Aldave AJ.

Genet Med. 2007 Apr;9(4):228-34.PMID: 17438387 [PubMed - indexed for MEDLINE]Related articles

Association of the Asn306Ser variant of the SP4 transcription factor and an intronic variant in the beta-subunit of transducin with digenic disease.

Gao YQ, Danciger M, Ozgul RK, Gribanova Y, Jacobson S, Farber DB.

Mol Vis. 2007 Feb 28;13:287-92.PMID: 17356515 [PubMed - indexed for MEDLINE]Related articlesFree article

Transcriptional and post-transcriptional regulation of the rod cGMP-phosphodiesterase beta-subunit gene. Recent advances and current concepts.

Lerner LE, Piri N, Farber DB.

Adv Exp Med Biol. 2006;572:217-29. Review. No abstract available. PMID: 17249578 [PubMed - indexed for MEDLINE]Related articles

Removal of phosphorylation sites of gamma subunit of phosphodiesterase 6 alters rod light response.

Tsang SH, Woodruff ML, Janisch KM, Cilluffo MC, Farber DB, Fain GL.

J Physiol. 2007 Mar 1;579(Pt 2):303-12. Epub 2006 Nov 30.PMID: 17138607 [PubMed - indexed for MEDLINE]Related articlesFree article

Transgenic mice carrying the H258N mutation in the gene encoding the beta-subunit of phosphodiesterase-6 (PDE6B) provide a model for human congenital stationary night blindness.

Tsang SH, Woodruff ML, Jun L, Mahajan V, Yamashita CK, Pedersen R, Lin CS, Goff SP, Rosenberg T, Larsen M, Farber DB, Nusinowitz S.

Hum Mutat. 2007 Mar;28(3):243-54.PMID: 17044014 [PubMed - indexed for MEDLINE]Related articlesFree article

Translational regulation of the rod photoreceptor cGMP-phosphodiesterase: the role of the 5'- and 3'-untranslated regions.

Piri N, Mendoza E, Shih J, Yamashita CK, Akhmedov NB, Farber DB.

Exp Eye Res. 2006 Oct;83(4):841-8.PMID: 16765946 [PubMed - indexed for MEDLINE]Related articles

GAP-independent termination of photoreceptor light response by excess gamma subunit of the cGMP-phosphodiesterase.

Tsang SH, Woodruff ML, Chen CK, Yamashita CY, Cilluffo MC, Rao AL, Farber DB, Fain GL.

J Neurosci. 2006 Apr 26;26(17):4472-80.PMID: 16641226 [PubMed - indexed for MEDLINE]Related articlesFree article

Disruption of the gene encoding the beta1-subunit of transducin in the Rd4/+ mouse.

Kitamura E, Danciger M, Yamashita C, Rao NP, Nusinowitz S, Chang B, Farber DB.

Invest Ophthalmol Vis Sci. 2006 Apr;47(4):1293-301.PMID: 16565360 [PubMed - indexed for MEDLINE]Related articlesFree article

Morphological characterization of the retinal degeneration in three strains of mice carrying the rd-3 mutation.

Linberg KA, Fariss RN, Heckenlively JR, Farber DB, Fisher SK.

Vis Neurosci. 2005 Nov-Dec;22(6):721-34.PMID: 16469183 [PubMed - indexed for MEDLINE]Related articles

Early markers of retinal degeneration in rd/rd mice.

Acosta ML, Fletcher EL, Azizoglu S, Foster LE, Farber DB, Kalloniatis M.

Mol Vis. 2005 Sep 6;11:717-28.PMID: 16163270 [PubMed - indexed for MEDLINE]Related articlesFree article

Sp4 is expressed in retinal neurons, activates transcription of photoreceptor-specific genes, and synergizes with Crx.

Lerner LE, Peng GH, Gribanova YE, Chen S, Farber DB.

J Biol Chem. 2005 May 27;280(21):20642-50. Epub 2005 Mar 21.PMID: 15781457 [PubMed - indexed for MEDLINE]Related articlesFree article

Two forms of the large tumor suppressor gene (Lats1) protein expressed in the vertebrate retina.

Akhmedov NB, Yamashita CK, Tran D, Piri NI, Aguirre GD, Farber DB.

Biochim Biophys Acta. 2005 Apr 5;1728(1-2):11-7. Epub 2005 Jan 28.PMID: 15777619 [PubMed - indexed for MEDLINE]Related articles

A substitution of G to C in the cone cGMP-phosphodiesterase gamma subunit gene found in a distinctive form of cone dystrophy.

Piri N, Gao YQ, Danciger M, Mendoza E, Fishman GA, Farber DB.

Ophthalmology. 2005 Jan;112(1):159-66.PMID: 15629837 [PubMed - indexed for MEDLINE]Related articles

Glial transcytosis of a photoreceptor-secreted signaling protein, retinoschisin.

Reid SN, Farber DB.

Glia. 2005 Feb;49(3):397-406.PMID: 15538749 [PubMed - indexed for MEDLINE]Related articles

Conserved transcriptional regulation of a cone phototransduction gene in vertebrates.

Viczian AS, Verardo M, Zuber ME, Knox BE, Farber DB.

FEBS Lett. 2004 Nov 5;577(1-2):259-64.PMID: 15527796 [PubMed - indexed for MEDLINE]Related articles

Molecular analysis of the ABCA4 gene in Turkish patients with Stargardt disease and retinitis pigmentosa.

Ozgül RK, Durukan H, Turan A, Oner C, Ogüs A, Farber DB.

Hum Mutat. 2004 May;23(5):523.PMID: 15108289 [PubMed - indexed for MEDLINE]Related articles

Differential expression of rod photoreceptor cGMP-phosphodiesterase alpha and beta subunits: mRNA and protein levels.

Piri N, Yamashita CK, Shih J, Akhmedov NB, Farber DB.

J Biol Chem. 2003 Sep 26;278(39):36999-7005. Epub 2003 Jul 18.PMID: 12871955 [PubMed - indexed for MEDLINE]Related articlesFree article

Retinoschisin, a photoreceptor-secreted protein, and its interaction with bipolar and muller cells.

Reid SN, Yamashita C, Farber DB.

J Neurosci. 2003 Jul 9;23(14):6030-40.PMID: 12853421 [PubMed - indexed for MEDLINE]Related articlesFree article

Stationary night blindness or progressive retinal degeneration in mice carrying different alleles of PDE gamma.

Farber DB, Tsang SH.

Front Biosci. 2003 May 1;8:s666-75. Review.PMID: 12700134 [PubMed - indexed for MEDLINE]Related articles

Evaluation of techniques using amplified nucleic acid probes for gene expression profiling.

Saghizadeh M, Brown DJ, Tajbakhsh J, Chen Z, Kenney MC, Farber DB, Nelson SF.

Biomol Eng. 2003 Mar;20(3):97-106.PMID: 12684071 [PubMed - indexed for MEDLINE]Related articles

Expression of cone photoreceptor cGMP-phosphodiesterase alpha' subunit in Chinese hamster ovary, 293 human embryonic kidney, and Y79 retinoblastoma cells.

Piriev NI, Yamashita CK, Shih J, Farber DB.

Mol Vis. 2003 Mar 24;9:80-6.PMID: 12655284 [PubMed - indexed for MEDLINE]Related articlesFree article

Progressive photoreceptor degeneration, outer segment dysplasia, and rhodopsin mislocalization in mice with targeted disruption of the retinitis pigmentosa-1 (Rp1) gene.

Gao J, Cheon K, Nusinowitz S, Liu Q, Bei D, Atkins K, Azimi A, Daiger SP, Farber DB, Heckenlively JR, Pierce EA, Sullivan LS, Zuo J.

Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5698-703.PMID: 11960024 [PubMed - indexed for MEDLINE]Related articlesFree article

Cloning and characterization of the canine photoreceptor specific cone-rod homeobox (CRX) gene and evaluation as a candidate for early onset photoreceptor diseases in the dog.

Akhmedov NB, Baldwin VJ, Zangerl B, Kijas JW, Hunter L, Minoofar KD, Mellersh C, Ostrander EA, Acland GM, Farber DB, Aguirre GD.

Mol Vis. 2002 Mar 22;8:79-84.PMID: 11951083 [PubMed - indexed for MEDLINE]Related articlesFree article

The rod cGMP-phosphodiesterase beta-subunit promoter is a specific target for Sp4 and is not activated by other Sp proteins or CRX.

Lerner LE, Gribanova YE, Whitaker L, Knox BE, Farber DB.

J Biol Chem. 2002 Jul 19;277(29):25877-83. Epub 2002 Apr 9.PMID: 11943774 [PubMed - indexed for MEDLINE]Related articlesFree article

The positive role of the carboxyl terminus of the gamma subunit of retinal cGMP-phosphodiesterase in maintaining phosphodiesterase activity in vivo.

Tsang SH, Yamashita CK, Lee WH, Lin CS, Goff SP, Gouras P, Farber DB.

Vision Res. 2002 Feb;42(4):439-45.PMID: 11853759 [PubMed - indexed for MEDLINE]Related articles

Identification and subcellular localization of the RP1 protein in human and mouse photoreceptors.

Liu Q, Zhou J, Daiger SP, Farber DB, Heckenlively JR, Smith JE, Sullivan LS, Zuo J, Milam AH, Pierce EA.

Invest Ophthalmol Vis Sci. 2002 Jan;43(1):22-32.PMID: 11773008 [PubMed - indexed for MEDLINE]Related articlesFree article

CORD9 a new locus for arCRD: mapping to 8p11, estimation of frequency, evaluation of a candidate gene.

Danciger M, Hendrickson J, Lyon J, Toomes C, McHale JC, Fishman GA, Inglehearn CF, Jacobson SG, Farber DB.

Invest Ophthalmol Vis Sci. 2001 Oct;42(11):2458-65.PMID: 11581183 [PubMed - indexed for MEDLINE]Related articlesFree article

Nrl and Sp nuclear proteins mediate transcription of rod-specific cGMP-phosphodiesterase beta-subunit gene: involvement of multiple response elements.

Lerner LE, Gribanova YE, Ji M, Knox BE, Farber DB.

J Biol Chem. 2001 Sep 14;276(37):34999-5007. Epub 2001 Jul 3.PMID: 11438531 [PubMed - indexed for MEDLINE]Related articlesFree article

In vivo studies of the gamma subunit of retinal cGMP-phophodiesterase with a substitution of tyrosine-84.

Tsang SH, Yamashita CK, Doi K, Salchow DJ, Bouvier N, Mendelsohn M, Gouras P, Farber DB, Goff SP.

Biochem J. 2001 Feb 1;353(Pt 3):467-74.PMID: 11171042 [PubMed - indexed for MEDLINE]Related articlesFree article

The human cGMP-PDE beta-subunit promoter region directs expression of the gene to mouse photoreceptors.

Ogueta SB, Di Polo A, Flannery JG, Yamashita CK, Farber DB.

Invest Ophthalmol Vis Sci. 2000 Dec;41(13):4059-63.PMID: 11095595 [PubMed - indexed for MEDLINE]Related articlesFree article

A homozygous deletion in RPE65 in a small Sardinian family with autosomal recessive retinal dystrophy.

Poehner WJ, Fossarello M, Rapoport AL, Aleman TS, Cideciyan AV, Jacobson SG, Wright AF, Danciger M, Farber DB.

Mol Vis. 2000 Oct 30;6:192-8.PMID: 11062306 [PubMed - indexed for MEDLINE]Related articlesFree article

Retinoschisin, the X-linked retinoschisis protein, is a secreted photoreceptor protein, and is expressed and released by Weri-Rb1 cells.

Grayson C, Reid SN, Ellis JA, Rutherford A, Sowden JC, Yates JR, Farber DB, Trump D.

Hum Mol Genet. 2000 Jul 22;9(12):1873-9.PMID: 10915776 [PubMed - indexed for MEDLINE]Related articlesFree article

Disease expression of RP1 mutations causing autosomal dominant retinitis pigmentosa.

Jacobson SG, Cideciyan AV, Iannaccone A, Weleber RG, Fishman GA, Maguire AM, Affatigato LM, Bennett J, Pierce EA, Danciger M, Farber DB, Stone EM.

Invest Ophthalmol Vis Sci. 2000 Jun;41(7):1898-908.PMID: 10845615 [PubMed - indexed for MEDLINE]Related articlesFree article

A QTL on distal chromosome 3 that influences the severity of light-induced damage to mouse photoreceptors.

Danciger M, Matthes MT, Yasamura D, Akhmedov NB, Rickabaugh T, Gentleman S, Redmond TM, La Vail MM, Farber DB.

Mamm Genome. 2000 Jun;11(6):422-7.PMID: 10818205 [PubMed - indexed for MEDLINE]Related articles

A deletion in a photoreceptor-specific nuclear receptor mRNA causes retinal degeneration in the rd7 mouse.

Akhmedov NB, Piriev NI, Chang B, Rapoport AL, Hawes NL, Nishina PM, Nusinowitz S, Heckenlively JR, Roderick TH, Kozak CA, Danciger M, Davisson MT, Farber DB.

Proc Natl Acad Sci U S A. 2000 May 9;97(10):5551-6.PMID: 10805811 [PubMed - indexed for MEDLINE]Related articlesFree article

Construction of encapsidated (gutted) adenovirus minichromosomes and their application to rescue of photoreceptor degeneration.

Kumar-Singh R, Yamashita CK, Tran K, Farber DB.

Methods Enzymol. 2000;316:724-43. No abstract available. PMID: 10800711 [PubMed - indexed for MEDLINE]Related articles

Transcriptional regulation of the cGMP phosphodiesterase beta-subunit gene.

Lerner LE, Farber DB.

Methods Enzymol. 2000;315:617-35. No abstract available. PMID: 10736730 [PubMed - indexed for MEDLINE]Related articles

Estrogen receptor in the human eye: influence of gender and age on gene expression.

Ogueta SB, Schwartz SD, Yamashita CK, Farber DB.

Invest Ophthalmol Vis Sci. 1999 Aug;40(9):1906-11.PMID: 10440242 [PubMed - indexed for MEDLINE]Related articlesFree article

Photoreceptor cell damage by light in young Royal College of Surgeons rats.

Organisciak DT, Li M, Darrow RM, Farber DB.

Curr Eye Res. 1999 Aug;19(2):188-96.PMID: 10420189 [PubMed - indexed for MEDLINE]Related articles

A nonsense mutation in a novel gene is associated with retinitis pigmentosa in a family linked to the RP1 locus.

Guillonneau X, Piriev NI, Danciger M, Kozak CA, Cideciyan AV, Jacobson SG, Farber DB.

Hum Mol Genet. 1999 Aug;8(8):1541-6.PMID: 10401003 [PubMed - indexed for MEDLINE]Related articlesFree article

Screening of the gene encoding the alpha'-subunit of cone cGMP-PDE in patients with retinal degenerations.

Gao YQ, Danciger M, Longmuir R, Piriev NI, Zhao DY, Heckenlively JR, Fishman GA, Weleber RG, Jacobson SG, Stone EM, Farber DB.

Invest Ophthalmol Vis Sci. 1999 Jul;40(8):1818-22.PMID: 10393054 [PubMed - indexed for MEDLINE]Related articlesFree article