PubMed

Genome-Wide Association Study of Generalized Vitiligo in an Isolated European Founder Population Identifies SMOC2, in Close Proximity to IDDM8.

Birlea SA, Gowan K, Fain PR, Spritz RA.

J Invest Dermatol. 2009 Nov 5. [Epub ahead of print]PMID: 19890347 [PubMed - as supplied by publisher]Related articles

Homozygosity of the polymorphism MICA5.1 identifies extreme risk of progression to overt adrenal insufficiency among 21-hydroxylase antibody-positive patients with type 1 diabetes.

Triolo TM, Baschal EE, Armstrong TK, Toews CS, Fain PR, Rewers MJ, Yu L, Miao D, Eisenbarth GS, Gottlieb PA, Barker JM.

J Clin Endocrinol Metab. 2009 Nov;94(11):4517-23. Epub 2009 Oct 9.PMID: 19820007 [PubMed - in process]Related articles

Haplotype and cell proliferation analyses of candidate lung cancer susceptibility genes on chromosome 15q24-25.1.

Liu Y, Liu P, Wen W, James MA, Wang Y, Bailey-Wilson JE, Amos CI, Pinney SM, Yang P, de Andrade M, Petersen GM, Wiest JS, Fain PR, Schwartz AG, Gazdar A, Gaba C, Rothschild H, Mandal D, Kupert E, Lee J, Seminara D, Minna J, Anderson MW, You M.

Cancer Res. 2009 Oct 1;69(19):7844-50. Epub 2009 Sep 29.PMID: 19789337 [PubMed - in process]Related articles

Fine-Mapping of Vitiligo Susceptibility Loci on Chromosomes 7 and 9 and Interactions with NLRP1 (NALP1).

Jin Y, Riccardi SL, Gowan K, Fain PR, Spritz RA.

J Invest Dermatol. 2009 Sep 3. [Epub ahead of print]PMID: 19727120 [PubMed - as supplied by publisher]Related articles

Functional and genetic evidence that the Mal/TIRAP allele variant 180L has been selected by providing protection against septic shock.

Ferwerda B, Alonso S, Banahan K, McCall MB, Giamarellos-Bourboulis EJ, Ramakers BP, Mouktaroudi M, Fain PR, Izagirre N, Syafruddin D, Cristea T, Mockenhaupt FP, Troye-Blomberg M, Kumpf O, Maiga B, Dolo A, Doumbo O, Sundaresan S, Bedu-Addo G, van Crevel R, Hamann L, Oh DY, Schumann RR, Joosten LA, de la Rúa C, Sauerwein R, Drenth JP, Kullberg BJ, van der Ven AJ, Hill AV, Pickkers P, van der Meer JW, O'Neill LA, Netea MG.

Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10272-7. Epub 2009 Jun 9.PMID: 19509334 [PubMed - indexed for MEDLINE]Related articles

Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 as a likely candidate gene.

You M, Wang D, Liu P, Vikis H, James M, Lu Y, Wang Y, Wang M, Chen Q, Jia D, Liu Y, Wen W, Yang P, Sun Z, Pinney SM, Zheng W, Shu XO, Long J, Gao YT, Xiang YB, Chow WH, Rothman N, Petersen GM, de Andrade M, Wu Y, Cunningham JM, Wiest JS, Fain PR, Schwartz AG, Girard L, Gazdar A, Gaba C, Rothschild H, Mandal D, Coons T, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Amos CI, Anderson MW.

Clin Cancer Res. 2009 Apr 15;15(8):2666-74. Epub 2009 Apr 7.PMID: 19351763 [PubMed - indexed for MEDLINE]Related articles

CTLA4 and generalized vitiligo: two genetic association studies and a meta-analysis of published data.

Birlea SA, Laberge GS, Procopciuc LM, Fain PR, Spritz RA.

Pigment Cell Melanoma Res. 2009 Apr;22(2):230-4. Epub 2009 Jan 17.PMID: 19175525 [PubMed - indexed for MEDLINE]Related articlesFree article

Concordance for islet autoimmunity among monozygotic twins.

Redondo MJ, Jeffrey J, Fain PR, Eisenbarth GS, Orban T.

N Engl J Med. 2008 Dec 25;359(26):2849-50. No abstract available. PMID: 19109586 [PubMed - indexed for MEDLINE]Related articles

Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer.

Liu P, Vikis HG, Wang D, Lu Y, Wang Y, Schwartz AG, Pinney SM, Yang P, de Andrade M, Petersen GM, Wiest JS, Fain PR, Gazdar A, Gaba C, Rothschild H, Mandal D, Coons T, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Wu X, Spitz MR, Eisen T, Houlston RS, Amos CI, Anderson MW, You M.

J Natl Cancer Inst. 2008 Sep 17;100(18):1326-30. Epub 2008 Sep 9.PMID: 18780872 [PubMed - indexed for MEDLINE]Related articlesFree article

Presence of de novo mutations in autosomal dominant polycystic kidney disease patients without family history.

Reed B, McFann K, Kimberling WJ, Pei Y, Gabow PA, Christopher K, Petersen E, Kelleher C, Fain PR, Johnson A, Schrier RW.

Am J Kidney Dis. 2008 Dec;52(6):1042-50. Epub 2008 Jul 21.PMID: 18640754 [PubMed - indexed for MEDLINE]Related articles

The PTPN22-1858C>T (R620W) functional polymorphism is associated with generalized vitiligo in the Romanian population.

Laberge GS, Birlea SA, Fain PR, Spritz RA.

Pigment Cell Melanoma Res. 2008 Apr;21(2):206-8.PMID: 18426414 [PubMed - indexed for MEDLINE]Related articles

A Romanian population isolate with high frequency of vitiligo and associated autoimmune diseases.

Birlea SA, Fain PR, Spritz RA.

Arch Dermatol. 2008 Mar;144(3):310-6.PMID: 18347286 [PubMed - indexed for MEDLINE]Related articlesFree article

PTPN22 is genetically associated with risk of generalized vitiligo, but CTLA4 is not.

LaBerge GS, Bennett DC, Fain PR, Spritz RA.

J Invest Dermatol. 2008 Jul;128(7):1757-62. Epub 2008 Jan 17.PMID: 18200060 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of single nucleotide polymorphisms identifies major type 1A diabetes locus telomeric of the major histocompatibility complex.

Aly TA, Baschal EE, Jahromi MM, Fernando MS, Babu SR, Fingerlin TE, Kretowski A, Erlich HA, Fain PR, Rewers MJ, Eisenbarth GS.

Diabetes. 2008 Mar;57(3):770-6. Epub 2007 Dec 7.PMID: 18065518 [PubMed - indexed for MEDLINE]Related articlesFree article

Vitiligo-associated multiple autoimmune disease is not associated with genetic variation in AIRE.

Jin Y, Bennett DC, Amadi-Myers A, Holland P, Riccardi SL, Gowan K, Fain PR, Spritz RA.

Pigment Cell Res. 2007 Oct;20(5):402-4. No abstract available. PMID: 17850514 [PubMed - indexed for MEDLINE]Related articles

Differential effects of DRB1*0301 and DQA1*0501-DQB1*0201 on the activation and progression of islet cell autoimmunity.

Eller E, Vardi P, McFann KK, Babu SR, Yu L, Bugawan TL, Erlich HA, Eisenbarth GS, Fain PR.

Genes Immun. 2007 Dec;8(8):628-33. Epub 2007 Aug 30.PMID: 17728790 [PubMed - indexed for MEDLINE]Related articles

Genetic variations in NALP1 are associated with generalized vitiligo in a Romanian population.

Jin Y, Birlea SA, Fain PR, Spritz RA.

J Invest Dermatol. 2007 Nov;127(11):2558-62. Epub 2007 Jul 19.PMID: 17637824 [PubMed - indexed for MEDLINE]Related articlesFree article

EGFR-T790M is a rare lung cancer susceptibility allele with enhanced kinase activity.

Vikis H, Sato M, James M, Wang D, Wang Y, Wang M, Jia D, Liu Y, Bailey-Wilson JE, Amos CI, Pinney SM, Petersen GM, de Andrade M, Yang P, Wiest JS, Fain PR, Schwartz AG, Gazdar A, Gaba C, Rothschild H, Mandal D, Kupert E, Seminara D, Viswanathan A, Govindan R, Minna J, Anderson MW, You M.

Cancer Res. 2007 May 15;67(10):4665-70.PMID: 17510392 [PubMed - indexed for MEDLINE]Related articlesFree article

NALP1 in vitiligo-associated multiple autoimmune disease.

Jin Y, Mailloux CM, Gowan K, Riccardi SL, LaBerge G, Bennett DC, Fain PR, Spritz RA.

N Engl J Med. 2007 Mar 22;356(12):1216-25.PMID: 17377159 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of a novel tumor suppressor gene p34 on human chromosome 6q25.1.

Wang M, Vikis HG, Wang Y, Jia D, Wang D, Bierut LJ, Bailey-Wilson JE, Amos CI, Pinney SM, Petersen GM, de Andrade M, Yang P, Wiest JS, Fain PR, Schwartz AG, Gazdar A, Minna J, Gaba C, Rothschild H, Mandal D, Kupert E, Seminara D, Liu Y, Viswanathan A, Govindan R, Anderson MW, You M.

Cancer Res. 2007 Jan 1;67(1):93-9.PMID: 17210687 [PubMed - indexed for MEDLINE]Related articlesFree article

Celiac disease and HLA in a Bedouin kindred.

Eller E, Vardi P, Babu SR, Bugawan TL, Erlich HA, Yu L, Fain PR.

Hum Immunol. 2006 Nov;67(11):940-50. Epub 2006 Sep 18.PMID: 17145374 [PubMed - indexed for MEDLINE]Related articlesFree article

Extreme genetic risk for type 1A diabetes.

Aly TA, Ide A, Jahromi MM, Barker JM, Fernando MS, Babu SR, Yu L, Miao D, Erlich HA, Fain PR, Barriga KJ, Norris JM, Rewers MJ, Eisenbarth GS.

Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):14074-9. Epub 2006 Sep 11.PMID: 16966600 [PubMed - indexed for MEDLINE]Related articlesFree article

Conserved extended haplotypes discriminate HLA-DR3-homozygous Basque patients with type 1 diabetes mellitus and celiac disease.

Bilbao JR, Calvo B, Aransay AM, Martin-Pagola A, Perez de Nanclares G, Aly TA, Rica I, Vitoria JC, Gaztambide S, Noble J, Fain PR, Awdeh ZL, Alper CA, Castaño L.

Genes Immun. 2006 Oct;7(7):550-4. Epub 2006 Aug 24.PMID: 16929349 [PubMed - indexed for MEDLINE]Related articles

Multi-SNP analysis of MHC region: remarkable conservation of HLA-A1-B8-DR3 haplotype.

Aly TA, Eller E, Ide A, Gowan K, Babu SR, Erlich HA, Rewers MJ, Eisenbarth GS, Fain PR.

Diabetes. 2006 May;55(5):1265-9.PMID: 16644681 [PubMed - indexed for MEDLINE]Related articlesFree article

HLA class II haplotype DRB1*04-DQB1*0301 contributes to risk of familial generalized vitiligo and early disease onset.

Fain PR, Babu SR, Bennett DC, Spritz RA.

Pigment Cell Res. 2006 Feb;19(1):51-7.PMID: 16420246 [PubMed - indexed for MEDLINE]Related articles

Thymopoietin (lamina-associated polypeptide 2) gene mutation associated with dilated cardiomyopathy.

Taylor MR, Slavov D, Gajewski A, Vlcek S, Ku L, Fain PR, Carniel E, Di Lenarda A, Sinagra G, Boucek MM, Cavanaugh J, Graw SL, Ruegg P, Feiger J, Zhu X, Ferguson DA, Bristow MR, Gotzmann J, Foisner R, Mestroni L; Familial Cardiomyopathy Registry Research Group.

Hum Mutat. 2005 Dec;26(6):566-74.PMID: 16247757 [PubMed - indexed for MEDLINE]Related articles

Homozygosity for premature stop codon of the MHC class I chain-related gene A (MIC-A) is associated with early activation of islet autoimmunity of DR3/4-DQ2/8 high risk DAISY relatives.

Ide A, Babu SR, Robles DT, Wang T, Erlich HA, Bugawan TL, Rewers M, Fain PR, Eisenbarth GS.

J Clin Immunol. 2005 Jul;25(4):303-8.PMID: 16133985 [PubMed - indexed for MEDLINE]Related articles

Candidate functional promoter variant in the FOXD3 melanoblast developmental regulator gene in autosomal dominant vitiligo.

Alkhateeb A, Fain PR, Spritz RA.

J Invest Dermatol. 2005 Aug;125(2):388-91. No abstract available. PMID: 16098053 [PubMed - indexed for MEDLINE]Related articles

Early disease onset and increased risk of other autoimmune diseases in familial generalized vitiligo.

Laberge G, Mailloux CM, Gowan K, Holland P, Bennett DC, Fain PR, Spritz RA.

Pigment Cell Res. 2005 Aug;18(4):300-5.PMID: 16029422 [PubMed - indexed for MEDLINE]Related articles

Alpha-myosin heavy chain: a sarcomeric gene associated with dilated and hypertrophic phenotypes of cardiomyopathy.

Carniel E, Taylor MR, Sinagra G, Di Lenarda A, Ku L, Fain PR, Boucek MM, Cavanaugh J, Miocic S, Slavov D, Graw SL, Feiger J, Zhu XZ, Dao D, Ferguson DA, Bristow MR, Mestroni L.

Circulation. 2005 Jul 5;112(1):54-9.PMID: 15998695 [PubMed - indexed for MEDLINE]Related articlesFree article

"Extended" A1, B8, DR3 haplotype shows remarkable linkage disequilibrium but is similar to nonextended haplotypes in terms of diabetes risk.

Ide A, Babu SR, Robles DT, Wang T, Erlich HA, Bugawan TL, Rewers M, Fain PR, Eisenbarth GS.

Diabetes. 2005 Jun;54(6):1879-83.PMID: 15919812 [PubMed - indexed for MEDLINE]Related articlesFree article

Modifier genes play a significant role in the phenotypic expression of PKD1.

Fain PR, McFann KK, Taylor MR, Tison M, Johnson AM, Reed B, Schrier RW.

Kidney Int. 2005 Apr;67(4):1256-67.PMID: 15780078 [PubMed - indexed for MEDLINE]Related articles

A second-generation genome screen for linkage to type 1 diabetes in a Bedouin Arab family.

Babu SR, Conant GC, Eller E, Roberts CM, Gowan K, Eisenbarth GS, Fain PR, Vardi P.

Ann N Y Acad Sci. 2004 Dec;1037:157-60.PMID: 15699511 [PubMed - indexed for MEDLINE]Related articles

IDDM17: polymorphisms in the AMACO gene are associated with dominant protection against type 1A diabetes in a Bedouin Arab family.

Eller E, Vardi P, Daly MJ, Babu S, Roberts C, Yang F, Eisenbarth GS, Fain PR.

Ann N Y Acad Sci. 2004 Dec;1037:145-9.PMID: 15699509 [PubMed - indexed for MEDLINE]Related articles

Progressive loss of renal function is an age-dependent heritable trait in type 1 autosomal dominant polycystic kidney disease.

Paterson AD, Magistroni R, He N, Wang K, Johnson A, Fain PR, Dicks E, Parfrey P, St George-Hyslop P, Pei Y.

J Am Soc Nephrol. 2005 Mar;16(3):755-62. Epub 2005 Jan 26.PMID: 15677307 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of beta-cell autoimmunity does not differ between potential dizygotic twins and siblings of patients with type 1 diabetes.

Redondo MJ, Fain PR, Krischer JP, Yu L, Cuthbertson D, Winter WE, Eisenbarth GS; DPT-1 Study Group.

J Autoimmun. 2004 Nov;23(3):275-9.PMID: 15501398 [PubMed - indexed for MEDLINE]Related articles

Endocrine and immunogenetic testing in individuals with type 1 diabetes and 21-hydroxylase autoantibodies: Addison's disease in a high-risk population.

Barker JM, Ide A, Hostetler C, Yu L, Miao D, Fain PR, Eisenbarth GS, Gottlieb PA.

J Clin Endocrinol Metab. 2005 Jan;90(1):128-34. Epub 2004 Oct 13.PMID: 15483092 [PubMed - indexed for MEDLINE]Related articlesFree article

SCN5A mutation associated with dilated cardiomyopathy, conduction disorder, and arrhythmia.

McNair WP, Ku L, Taylor MR, Fain PR, Dao D, Wolfel E, Mestroni L; Familial Cardiomyopathy Registry Research Group.

Circulation. 2004 Oct 12;110(15):2163-7. Epub 2004 Oct 4.PMID: 15466643 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel vitiligo susceptibility loci on chromosomes 7 (AIS2) and 8 (AIS3), confirmation of SLEV1 on chromosome 17, and their roles in an autoimmune diathesis.

Spritz RA, Gowan K, Bennett DC, Fain PR.

Am J Hum Genet. 2004 Jan;74(1):188-91. No abstract available. PMID: 14691733 [PubMed - indexed for MEDLINE]Related articlesFree article

Single nucleotide polymorphism study of IDDM 17 in a Bedouin Arab family.

Bao F, Babu SR, Roberts CM, Martin AK, Gowan K, Eisenbarth GS, Fain PR.

Ann N Y Acad Sci. 2003 Nov;1005:348-51.PMID: 14679089 [PubMed - indexed for MEDLINE]Related articles

Caspase 7 is a positional candidate gene for IDDM 17 in a Bedouin Arab family.

Babu SR, Bao F, Roberts CM, Martin AK, Gowan K, Eisenbarth GS, Fain PR.

Ann N Y Acad Sci. 2003 Nov;1005:340-3.PMID: 14679087 [PubMed - indexed for MEDLINE]Related articles

Epidemiology of vitiligo and associated autoimmune diseases in Caucasian probands and their families.

Alkhateeb A, Fain PR, Thody A, Bennett DC, Spritz RA.

Pigment Cell Res. 2003 Jun;16(3):208-14.PMID: 12753387 [PubMed - indexed for MEDLINE]Related articles

A genomewide screen for generalized vitiligo: confirmation of AIS1 on chromosome 1p31 and evidence for additional susceptibility loci.

Fain PR, Gowan K, LaBerge GS, Alkhateeb A, Stetler GL, Talbert J, Bennett DC, Spritz RA.

Am J Hum Genet. 2003 Jun;72(6):1560-4. Epub 2003 Apr 18.PMID: 12707860 [PubMed - indexed for MEDLINE]Related articlesFree article

Natural history of dilated cardiomyopathy due to lamin A/C gene mutations.

Taylor MR, Fain PR, Sinagra G, Robinson ML, Robertson AD, Carniel E, Di Lenarda A, Bohlmeyer TJ, Ferguson DA, Brodsky GL, Boucek MM, Lascor J, Moss AC, Li WL, Stetler GL, Muntoni F, Bristow MR, Mestroni L; Familial Dilated Cardiomyopathy Registry Research Group.

J Am Coll Cardiol. 2003 Mar 5;41(5):771-80. Erratum in: J Am Coll Cardiol. 2003 Aug 6;42(3):590. PMID: 12628721 [PubMed - indexed for MEDLINE]Related articles

Exclusion of candidate genes and loci for multiple lentigines syndrome.

Pacheco TR, Bellus GA, Oreskovich NM, Talbert J, Old W, Fain PR.

J Invest Dermatol. 2002 Aug;119(2):535-8. No abstract available. PMID: 12190883 [PubMed - indexed for MEDLINE]Related articlesFree article

The genetics of autoimmune polyendocrine syndrome type II.

Robles DT, Fain PR, Gottlieb PA, Eisenbarth GS.

Endocrinol Metab Clin North Am. 2002 Jun;31(2):353-68, vi-vii. Review.PMID: 12092455 [PubMed - indexed for MEDLINE]Related articles

Mapping of an autoimmunity susceptibility locus (AIS1) to chromosome 1p31.3-p32.2.

Alkhateeb A, Stetler GL, Old W, Talbert J, Uhlhorn C, Taylor M, Fox A, Miller C, Dills DG, Ridgway EC, Bennett DC, Fain PR, Spritz RA.

Hum Mol Genet. 2002 Mar 15;11(6):661-7.PMID: 11912181 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetics of type 1A diabetes.

Redondo MJ, Fain PR, Eisenbarth GS.

Recent Prog Horm Res. 2001;56:69-89. Review.PMID: 11237226 [PubMed - indexed for MEDLINE]Related articlesFree article

X-Linked syndrome of polyendocrinopathy, immune dysfunction, and diarrhea maps to Xp11.23-Xq13.3.

Bennett CL, Yoshioka R, Kiyosawa H, Barker DF, Fain PR, Shigeoka AO, Chance PF.

Am J Hum Genet. 2000 Feb;66(2):461-8.PMID: 10677306 [PubMed - indexed for MEDLINE]Related articlesFree article

Transmission of DQ haplotypes to patients with type 1 diabetes.

Kawasaki E, Noble J, Erlich H, Mulgrew CL, Fain PR, Eisenbarth GS.

Diabetes. 1998 Dec;47(12):1971-3. No abstract available. PMID: 9836533 [PubMed - indexed for MEDLINE]Related articlesFree article