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A comparison of treatment thresholds in two large Parkinson's disease clinical trial cohorts.

Marras C, Lang AE, Eberly SW, Oakes D, Fahn S, Schwid SR, Hyson C, Shoulson I; of the Parkinson Study Group DATATOP and PRECEPT investigatorsSee appendix for the full list of DATATOP and PRECEPT investigators..

Mov Disord. 2009 Nov 11. [Epub ahead of print]PMID: 19908310 [PubMed - as supplied by publisher]Related articles

Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease.

Sidransky E, Nalls MA, Aasly JO, Aharon-Peretz J, Annesi G, Barbosa ER, Bar-Shira A, Berg D, Bras J, Brice A, Chen CM, Clark LN, Condroyer C, De Marco EV, Dürr A, Eblan MJ, Fahn S, Farrer MJ, Fung HC, Gan-Or Z, Gasser T, Gershoni-Baruch R, Giladi N, Griffith A, Gurevich T, Januario C, Kropp P, Lang AE, Lee-Chen GJ, Lesage S, Marder K, Mata IF, Mirelman A, Mitsui J, Mizuta I, Nicoletti G, Oliveira C, Ottman R, Orr-Urtreger A, Pereira LV, Quattrone A, Rogaeva E, Rolfs A, Rosenbaum H, Rozenberg R, Samii A, Samaddar T, Schulte C, Sharma M, Singleton A, Spitz M, Tan EK, Tayebi N, Toda T, Troiano AR, Tsuji S, Wittstock M, Wolfsberg TG, Wu YR, Zabetian CP, Zhao Y, Ziegler SG.

N Engl J Med. 2009 Oct 22;361(17):1651-61.PMID: 19846850 [PubMed - indexed for MEDLINE]Related articles

Urate as a Predictor of the Rate of Clinical Decline in Parkinson Disease.

Ascherio A, Lewitt PA, Xu K, Eberly S, Watts A, Matson WR, Marras C, Kieburtz K, Rudolph A, Bogdanov MB, Schwid SR, Tennis M, Tanner CM, Beal MF, Lang AE, Oakes D, Fahn S, Shoulson I, Schwarzschild MA; for the Parkinson Study Group DATATOP Investigators.

Arch Neurol. 2009 Oct 12. [Epub ahead of print]PMID: 19822770 [PubMed - as supplied by publisher]Related articles

A longitudinal program for biomarker development in Parkinson's disease: a feasibility study.

Ravina B, Tanner C, Dieuliis D, Eberly S, Flagg E, Galpern WR, Fahn S, Goetz CG, Grate S, Kurlan R, Lang AE, Marek K, Kieburtz K, Oakes D, Elliott R, Shoulson I; Parkinson Study Group LABS-PD Investigators.

Mov Disord. 2009 Oct 30;24(14):2081-90.PMID: 19691116 [PubMed - in process]Related articles

Association of glucocerebrosidase mutations with dementia with lewy bodies.

Clark LN, Kartsaklis LA, Wolf Gilbert R, Dorado B, Ross BM, Kisselev S, Verbitsky M, Mejia-Santana H, Cote LJ, Andrews H, Vonsattel JP, Fahn S, Mayeux R, Honig LS, Marder K.

Arch Neurol. 2009 May;66(5):578-83.PMID: 19433657 [PubMed - indexed for MEDLINE]Related articlesFree article

How do you treat motor complications in Parkinson's disease: Medicine, surgery, or both?

Fahn S.

Ann Neurol. 2008 Dec;64 Suppl 2:S56-64. Review.PMID: 19127577 [PubMed - indexed for MEDLINE]Related articles

Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): scale presentation and clinimetric testing results.

Goetz CG, Tilley BC, Shaftman SR, Stebbins GT, Fahn S, Martinez-Martin P, Poewe W, Sampaio C, Stern MB, Dodel R, Dubois B, Holloway R, Jankovic J, Kulisevsky J, Lang AE, Lees A, Leurgans S, LeWitt PA, Nyenhuis D, Olanow CW, Rascol O, Schrag A, Teresi JA, van Hilten JJ, LaPelle N; Movement Disorder Society UPDRS Revision Task Force.

Mov Disord. 2008 Nov 15;23(15):2129-70.PMID: 19025984 [PubMed - indexed for MEDLINE]Related articlesFree article

Myoclonus in complex regional pain syndrome.

Lang AE, Angel M, Bhatia K, Chen R, Fahn S, Hallett M, Schrag A, Thompson P.

Mov Disord. 2009 Jan 30;24(2):314-6; author reply 316. No abstract available. PMID: 18973259 [PubMed - indexed for MEDLINE]Related articles

The history of dopamine and levodopa in the treatment of Parkinson's disease.

Fahn S.

Mov Disord. 2008;23 Suppl 3:S497-508. Review.PMID: 18781671 [PubMed - indexed for MEDLINE]Related articles

Fatigue in levodopa-naive subjects with Parkinson disease.

Schifitto G, Friedman JH, Oakes D, Shulman L, Comella CL, Marek K, Fahn S; Parkinson Study Group ELLDOPA Investigators.

Neurology. 2008 Aug 12;71(7):481-5.PMID: 18695158 [PubMed - indexed for MEDLINE]Related articles

A study of chorea after tetrabenazine withdrawal in patients with Huntington disease.

Frank S, Ondo W, Fahn S, Hunter C, Oakes D, Plumb S, Marshall F, Shoulson I, Eberly S, Walker F, Factor S, Hunt V, Shinaman A, Jankovic J.

Clin Neuropharmacol. 2008 May-Jun;31(3):127-33.PMID: 18520979 [PubMed - indexed for MEDLINE]Related articles

Risk of Parkinson disease in carriers of parkin mutations: estimation using the kin-cohort method.

Wang Y, Clark LN, Louis ED, Mejia-Santana H, Harris J, Cote LJ, Waters C, Andrews H, Ford B, Frucht S, Fahn S, Ottman R, Rabinowitz D, Marder K.

Arch Neurol. 2008 Apr;65(4):467-74.PMID: 18413468 [PubMed - indexed for MEDLINE]Related articlesFree article

Serum urate as a predictor of clinical and radiographic progression in Parkinson disease.

Schwarzschild MA, Schwid SR, Marek K, Watts A, Lang AE, Oakes D, Shoulson I, Ascherio A; Parkinson Study Group PRECEPT Investigators, Hyson C, Gorbold E, Rudolph A, Kieburtz K, Fahn S, Gauger L, Goetz C, Seibyl J, Forrest M, Ondrasik J.

Arch Neurol. 2008 Jun;65(6):716-23. Epub 2008 Apr 14.PMID: 18413464 [PubMed - indexed for MEDLINE]Related articlesFree article

Relationship of clinical efficacy to postmortem-determined anatomic subthalamic stimulation in Parkinson syndrome.

McClelland S 3rd, Vonsattel JP, Garcia RE, Amaya MD, Winfield LM, Pullman SL, Yu Q, Fahn S, Ford B, Goodman RR.

Clin Neuropathol. 2007 Nov-Dec;26(6):267-75.PMID: 18232592 [PubMed - indexed for MEDLINE]Related articles

Placebo response in Parkinson's disease: comparisons among 11 trials covering medical and surgical interventions.

Goetz CG, Wuu J, McDermott MP, Adler CH, Fahn S, Freed CR, Hauser RA, Olanow WC, Shoulson I, Tandon PK; Parkinson Study Group, Leurgans S.

Mov Disord. 2008 Apr 15;23(5):690-9.PMID: 18228568 [PubMed - indexed for MEDLINE]Related articles

Mutations in the glucocerebrosidase gene are associated with early-onset Parkinson disease.

Clark LN, Ross BM, Wang Y, Mejia-Santana H, Harris J, Louis ED, Cote LJ, Andrews H, Fahn S, Waters C, Ford B, Frucht S, Ottman R, Marder K.

Neurology. 2007 Sep 18;69(12):1270-7.PMID: 17875915 [PubMed - indexed for MEDLINE]Related articles

Manganic encephalopathy due to "ephedrone" abuse.

Sanotsky Y, Lesyk R, Fedoryshyn L, Komnatska I, Matviyenko Y, Fahn S.

Mov Disord. 2007 Jul 15;22(9):1337-43.PMID: 17566121 [PubMed - indexed for MEDLINE]Related articles

Levodopa in the treatment of Parkinson's disease.

Fahn S.

J Neural Transm Suppl. 2006;(71):1-15. Review.PMID: 17447410 [PubMed - indexed for MEDLINE]Related articles

Construction and validation of a Parkinson's disease mutation genotyping array for the Parkin gene.

Clark LN, Haamer E, Mejia-Santana H, Harris J, Lesage S, Durr A, Bs SJ, Hedrich K, Louis ED, Cote LJ, Andrews H, Fahn S, Waters C, Ford B, Frucht S, Scott W, Klein C, Brice A, Roomere H, Ottman R, Marder K.

Mov Disord. 2007 May 15;22(7):932-7.PMID: 17415800 [PubMed - indexed for MEDLINE]Related articles

DLB and PDD boundary issues: diagnosis, treatment, molecular pathology, and biomarkers.

Lippa CF, Duda JE, Grossman M, Hurtig HI, Aarsland D, Boeve BF, Brooks DJ, Dickson DW, Dubois B, Emre M, Fahn S, Farmer JM, Galasko D, Galvin JE, Goetz CG, Growdon JH, Gwinn-Hardy KA, Hardy J, Heutink P, Iwatsubo T, Kosaka K, Lee VM, Leverenz JB, Masliah E, McKeith IG, Nussbaum RL, Olanow CW, Ravina BM, Singleton AB, Tanner CM, Trojanowski JQ, Wszolek ZK; DLB/PDD Working Group.

Neurology. 2007 Mar 13;68(11):812-9. Review.PMID: 17353469 [PubMed - indexed for MEDLINE]Related articles

Multiple system atrophy in a patient with the spinocerebellar ataxia 3 gene mutation.

Nirenberg MJ, Libien J, Vonsattel JP, Fahn S.

Mov Disord. 2007 Jan 15;22(2):251-4.PMID: 17133518 [PubMed - indexed for MEDLINE]Related articles

Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): Process, format, and clinimetric testing plan.

Goetz CG, Fahn S, Martinez-Martin P, Poewe W, Sampaio C, Stebbins GT, Stern MB, Tilley BC, Dodel R, Dubois B, Holloway R, Jankovic J, Kulisevsky J, Lang AE, Lees A, Leurgans S, LeWitt PA, Nyenhuis D, Olanow CW, Rascol O, Schrag A, Teresi JA, Van Hilten JJ, LaPelle N.

Mov Disord. 2007 Jan;22(1):41-7.PMID: 17115387 [PubMed - indexed for MEDLINE]Related articlesFree article

Frequency of LRRK2 mutations in early- and late-onset Parkinson disease.

Clark LN, Wang Y, Karlins E, Saito L, Mejia-Santana H, Harris J, Louis ED, Cote LJ, Andrews H, Fahn S, Waters C, Ford B, Frucht S, Ottman R, Marder K.

Neurology. 2006 Nov 28;67(10):1786-91. Epub 2006 Oct 18.PMID: 17050822 [PubMed - indexed for MEDLINE]Related articles

A new look at levodopa based on the ELLDOPA study.

Fahn S.

J Neural Transm Suppl. 2006;(70):419-26. Review.PMID: 17017562 [PubMed - indexed for MEDLINE]Related articles

Effects of tyramine administration in Parkinson's disease patients treated with selective MAO-B inhibitor rasagiline.

deMarcaida JA, Schwid SR, White WB, Blindauer K, Fahn S, Kieburtz K, Stern M, Shoulson I; Parkinson Study Group TEMPO; PRESTO Tyramine Substudy Investigators and Coordinators.

Mov Disord. 2006 Oct;21(10):1716-21.PMID: 16856145 [PubMed - indexed for MEDLINE]Related articles

Rasagiline-associated motor improvement in PD occurs without worsening of cognitive and behavioral symptoms.

Elmer L, Schwid S, Eberly S, Goetz C, Fahn S, Kieburtz K, Oakes D, Blindauer K, Salzman P, Oren S, Prisco UL, Stern M, Shoulson I; Parkinson Study Group TEMPO; PRESTO Investigators.

J Neurol Sci. 2006 Oct 25;248(1-2):78-83. Epub 2006 Jul 7.PMID: 16828804 [PubMed - indexed for MEDLINE]Related articles

Case-control study of the parkin gene in early-onset Parkinson disease.

Clark LN, Afridi S, Karlins E, Wang Y, Mejia-Santana H, Harris J, Louis ED, Cote LJ, Andrews H, Fahn S, Waters C, Ford B, Frucht S, Ottman R, Marder K.

Arch Neurol. 2006 Apr;63(4):548-52.PMID: 16606767 [PubMed - indexed for MEDLINE]Related articlesFree article

A randomized controlled trial of etilevodopa in patients with Parkinson disease who have motor fluctuations.

Blindauer K, Shoulson I, Oakes D, Kieburtz K, Schwid S, Fahn S, Stern M, Goetz C, Nutt J, Goren S, Sayag N, Scolnik M, Levy R, Eyal E, Salzman P, Pagano M; Parkinson Study Group.

Arch Neurol. 2006 Feb;63(2):210-6.PMID: 16476809 [PubMed - indexed for MEDLINE]Related articlesFree article

Rasagiline improves quality of life in patients with early Parkinson's disease.

Biglan KM, Schwid S, Eberly S, Blindauer K, Fahn S, Goren T, Kieburtz K, Oakes D, Plumb S, Siderowf A, Stern M, Shoulson I; Parkinson Study Group.

Mov Disord. 2006 May;21(5):616-23.PMID: 16450340 [PubMed - indexed for MEDLINE]Related articles

Treatment issues in psychogenic-neuropsychiatric movement disorders.

Williams DT, Ford B, Fahn S.

Adv Neurol. 2005;96:350-63. Review.PMID: 16383231 [PubMed - indexed for MEDLINE]Related articles

Movement disorders fellowship training program at Columbia University Medical Center in 2001-2002.

Portera-Cailliau C, Victor D, Frucht S, Fahn S.

Mov Disord. 2006 Apr;21(4):479-85.PMID: 16250019 [PubMed - indexed for MEDLINE]Related articles

Does levodopa slow or hasten the rate of progression of Parkinson's disease?

Fahn S; and the Parkinson Study Group.

J Neurol. 2005 Oct;252 Suppl 4:IV37-IV42. Review.PMID: 16222436 [PubMed - indexed for MEDLINE]Related articles

High-dosage vitamin E supplementation and all-cause mortality.

Marras C, Lang AE, Oakes D, McDermott MP, Kieburtz K, Shoulson I, Tanner CM, Fahn S.

Ann Intern Med. 2005 Jul 19;143(2):152-3; author reply 156-8. No abstract available. PMID: 16027463 [PubMed - indexed for MEDLINE]Related articlesFree article

Status of fetal tissue transplantation for the treatment of advanced Parkinson disease.

Greene PE, Fahn S.

Neurosurg Focus. 2002 Nov 15;13(5):e3. Review.PMID: 15769072 [PubMed - indexed for MEDLINE]Related articles

Contribution of aging to the severity of different motor signs in Parkinson disease.

Levy G, Louis ED, Cote L, Perez M, Mejia-Santana H, Andrews H, Harris J, Waters C, Ford B, Frucht S, Fahn S, Marder K.

Arch Neurol. 2005 Mar;62(3):467-72.PMID: 15767513 [PubMed - indexed for MEDLINE]Related articlesFree article

Neurodegeneration and neuroprotection in Parkinson disease.

Fahn S, Sulzer D.

NeuroRx. 2004 Jan;1(1):139-54. Review.PMID: 15717014 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of radiotracer imaging in Parkinson disease.

Ravina B, Eidelberg D, Ahlskog JE, Albin RL, Brooks DJ, Carbon M, Dhawan V, Feigin A, Fahn S, Guttman M, Gwinn-Hardy K, McFarland H, Innis R, Katz RG, Kieburtz K, Kish SJ, Lange N, Langston JW, Marek K, Morin L, Moy C, Murphy D, Oertel WH, Oliver G, Palesch Y, Powers W, Seibyl J, Sethi KD, Shults CW, Sheehy P, Stoessl AJ, Holloway R.

Neurology. 2005 Jan 25;64(2):208-15. Review.PMID: 15668415 [PubMed - indexed for MEDLINE]Related articles

Levodopa and the progression of Parkinson's disease.

Fahn S, Oakes D, Shoulson I, Kieburtz K, Rudolph A, Lang A, Olanow CW, Tanner C, Marek K; Parkinson Study Group.

N Engl J Med. 2004 Dec 9;351(24):2498-508.PMID: 15590952 [PubMed - indexed for MEDLINE]Related articlesFree article

Pilot association study of the beta-glucocerebrosidase N370S allele and Parkinson's disease in subjects of Jewish ethnicity.

Clark LN, Nicolai A, Afridi S, Harris J, Mejia-Santana H, Strug L, Cote LJ, Louis ED, Andrews H, Waters C, Ford B, Frucht S, Fahn S, Mayeux R, Ottman R, Marder K.

Mov Disord. 2005 Jan;20(1):100-3.PMID: 15517591 [PubMed - indexed for MEDLINE]Related articles

ALS lessons learned from other neurological diseases. Parkinson's disease.

Fahn S.

Amyotroph Lateral Scler Other Motor Neuron Disord. 2004 Sep;5 Suppl 1:26-30. Review. No abstract available. PMID: 15512865 [PubMed - indexed for MEDLINE]Related articles

Huntington's Disease-like 2 (HDL2) in North America and Japan.

Margolis RL, Holmes SE, Rosenblatt A, Gourley L, O'Hearn E, Ross CA, Seltzer WK, Walker RH, Ashizawa T, Rasmussen A, Hayden M, Almqvist EW, Harris J, Fahn S, MacDonald ME, Mysore J, Shimohata T, Tsuji S, Potter N, Nakaso K, Adachi Y, Nakashima K, Bird T, Krause A, Greenstein P.

Ann Neurol. 2004 Nov;56(5):670-4. Erratum in: Ann Neurol. 2004 Dec;56(6):911. PMID: 15468075 [PubMed - indexed for MEDLINE]Related articles

Subthalamic nucleus stimulation in advanced Parkinson's disease: blinded assessments at one year follow up.

Ford B, Winfield L, Pullman SL, Frucht SJ, Du Y, Greene P, Cheringal JH, Yu Q, Cote LJ, Fahn S, McKhann GM 2nd, Goodman RR.

J Neurol Neurosurg Psychiatry. 2004 Sep;75(9):1255-9.PMID: 15314110 [PubMed - indexed for MEDLINE]Related articlesFree article

Woman with a 26-year history of parkinsonism, supranuclear ophthalmoplegia, and loss of postural reflexes.

Gordon PH, Fahn S, Chin S, Golbe LI, Lynch T, Eidelberg D.

Mov Disord. 2004 Aug;19(8):950-61.PMID: 15300663 [PubMed - indexed for MEDLINE]Related articles

Pramipexole vs levodopa as initial treatment for Parkinson disease: a 4-year randomized controlled trial.

Holloway RG, Shoulson I, Fahn S, Kieburtz K, Lang A, Marek K, McDermott M, Seibyl J, Weiner W, Musch B, Kamp C, Welsh M, Shinaman A, Pahwa R, Barclay L, Hubble J, LeWitt P, Miyasaki J, Suchowersky O, Stacy M, Russell DS, Ford B, Hammerstad J, Riley D, Standaert D, Wooten F, Factor S, Jankovic J, Atassi F, Kurlan R, Panisset M, Rajput A, Rodnitzky R, Shults C, Petsinger G, Waters C, Pfeiffer R, Biglan K, Borchert L, Montgomery A, Sutherland L, Weeks C, DeAngelis M, Sime E, Wood S, Pantella C, Harrigan M, Fussell B, Dillon S, Alexander-Brown B, Rainey P, Tennis M, Rost-Ruffner E, Brown D, Evans S, Berry D, Hall J, Shirley T, Dobson J, Fontaine D, Pfeiffer B, Brocht A, Bennett S, Daigneault S, Hodgeman K, O'Connell C, Ross T, Richard K, Watts A; Parkinson Study Group.

Arch Neurol. 2004 Jul;61(7):1044-53. Erratum in: Arch Neurol. 2005 Mar;62(3):430. PMID: 15262734 [PubMed - indexed for MEDLINE]Related articlesFree article

Lack of familial aggregation of Parkinson disease and Alzheimer disease.

Levy G, Louis ED, Mejia-Santana H, Côté L, Andrews H, Harris J, Waters C, Ford B, Frucht S, Fahn S, Ottman R, Marder K.

Arch Neurol. 2004 Jul;61(7):1033-9.PMID: 15262733 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of an early-onset Parkinson's disease cohort for DJ-1 mutations.

Clark LN, Afridi S, Mejia-Santana H, Harris J, Louis ED, Cote LJ, Andrews H, Singleton A, Wavrant De-Vrieze F, Hardy J, Mayeux R, Fahn S, Waters C, Ford B, Frucht S, Ottman R, Marder K.

Mov Disord. 2004 Jul;19(7):796-800.PMID: 15254937 [PubMed - indexed for MEDLINE]Related articles

Reaction time and movement time after embryonic cell implantation in Parkinson disease.

Gordon PH, Yu Q, Qualls C, Winfield H, Dillon S, Greene PE, Fahn S, Breeze RE, Freed CR, Pullman SL.

Arch Neurol. 2004 Jun;61(6):858-61.PMID: 15210522 [PubMed - indexed for MEDLINE]Related articlesFree article

Diagnosis and management of pergolide-induced fibrosis.

Agarwal P, Fahn S, Frucht SJ.

Mov Disord. 2004 Jun;19(6):699-704.PMID: 15197712 [PubMed - indexed for MEDLINE]Related articles

Preoperative response to levodopa is the best predictor of transplant outcome.

Freed CR, Breeze RE, Fahn S, Eidelberg D.

Ann Neurol. 2004 Jun;55(6):896; author reply 896-7. No abstract available. PMID: 15174028 [PubMed - indexed for MEDLINE]Related articles

Effects of perceived treatment on quality of life and medical outcomes in a double-blind placebo surgery trial.

McRae C, Cherin E, Yamazaki TG, Diem G, Vo AH, Russell D, Ellgring JH, Fahn S, Greene P, Dillon S, Winfield H, Bjugstad KB, Freed CR.

Arch Gen Psychiatry. 2004 Apr;61(4):412-20. Erratum in: Arch Gen Psychiatry. 2004 Jun;61(6):627. PMID: 15066900 [PubMed - indexed for MEDLINE]Related articlesFree article