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A Translational Approach to Hypertensive Heart Disease.

Díez J, Frohlich ED.

Hypertension. 2009 Nov 23. [Epub ahead of print] No abstract available. PMID: 19933923 [PubMed - as supplied by publisher]Related articles

Role of beta-adrenergic receptor blocking agents in hypertensive diseases: personal thoughts as the controversy persists.

Frohlich ED.

Ther Adv Cardiovasc Dis. 2009 Dec;3(6):455-64. Epub 2009 Nov 6.PMID: 19897523 [PubMed - in process]Related articles

Angiotensin II, mechanotransduction, and pulsatile arterial hemodynamics in hypertension.

Lacolley P, Safar ME, Regnault V, Frohlich ED.

Am J Physiol Heart Circ Physiol. 2009 Nov;297(5):H1567-75. Epub 2009 Sep 4. Review.PMID: 19734358 [PubMed - indexed for MEDLINE]Related articles

Current challenges and unresolved problems in hypertensive disease.

Frohlich ED.

Med Clin North Am. 2009 May;93(3):527-40, Table of Contents. Review.PMID: 19427489 [PubMed - indexed for MEDLINE]Related articles

Hypertensive disease: current challenges, new concepts and management. Preface.

Frohlich ED.

Med Clin North Am. 2009 May;93(3):xv-xx. No abstract available. PMID: 19427488 [PubMed - indexed for MEDLINE]Related articles

Usefulness of heart rate as an independent predictor for survival after heart transplantation.

Anand RG, Reddy MT, Yau CL, Myers L, Amin RR, Stahls PF, Dumas D, Frohlich ED, Ventura HO.

Am J Cardiol. 2009 May 1;103(9):1290-4. Epub 2009 Mar 13.PMID: 19406274 [PubMed - indexed for MEDLINE]Related articles

Angiotensin blockade prevents salt-induced injury of the renal circulation in spontaneously hypertensive rats.

Susic D, Zhou X, Frohlich ED.

Am J Nephrol. 2009;29(6):639-45. Epub 2009 Jan 21.PMID: 19155618 [PubMed - indexed for MEDLINE]Related articles

Obesity: a central risk and cardiovascular target of the cardiometabolic syndrome.

Frohlich ED.

J Cardiometab Syndr. 2008 Summer;3(3):147-8. No abstract available. PMID: 18983330 [PubMed - indexed for MEDLINE]Related articles

Medication adherence in older clinic patients with hypertension after Hurricane Katrina: implications for clinical practice and disaster management.

Krousel-Wood MA, Islam T, Muntner P, Stanley E, Phillips A, Webber LS, Frohlich ED, Re RN.

Am J Med Sci. 2008 Aug;336(2):99-104.PMID: 18703901 [PubMed - indexed for MEDLINE]Related articlesFree article

Excitement of clinical investigation: new basic mechanisms of action after drug introduction.

Frohlich ED.

Hypertension. 2008 Sep;52(3):465-6. Epub 2008 Jul 21. No abstract available. PMID: 18645045 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardiovascular effects of prorenin blockade in genetically spontaneously hypertensive rats on normal and high-salt diet.

Susic D, Zhou X, Frohlich ED, Lippton H, Knight M.

Am J Physiol Heart Circ Physiol. 2008 Sep;295(3):H1117-H1121. Epub 2008 Jul 11.PMID: 18621861 [PubMed - indexed for MEDLINE]Related articlesFree article

Partial adherence to antihypertensive therapy fails to achieve full cardiovascular benefits in hypertensive rats.

Susic D, Krousel-Wood M, Zhou X, Frohlich ED.

Am J Med Sci. 2008 Jun;335(6):420-5.PMID: 18552570 [PubMed - indexed for MEDLINE]Related articles

Mechanisms underlying obesity associated with systemic and renal hemodynamics in essential hypertension.

Frohlich ED, Susic D.

Curr Hypertens Rep. 2008 Apr;10(2):151-5. Review.PMID: 18474183 [PubMed - indexed for MEDLINE]Related articles

An appeal for reimbursement for innovative prevention measures in patient cardiovascular education.

Frohlich ED.

Nat Clin Pract Cardiovasc Med. 2008 Apr;5(4):175. No abstract available. PMID: 18368009 [PubMed - indexed for MEDLINE]Related articles

Optimal treatment of hypertension with diastolic heart failure.

Susic D, Frohlich ED.

Heart Fail Clin. 2008 Jan;4(1):117-24. Review.PMID: 18313629 [PubMed - indexed for MEDLINE]Related articles

The aging hypertensive heart: a brief update.

Susic D, Frohlich ED.

Nat Clin Pract Cardiovasc Med. 2008 Feb;5(2):104-10. Review.PMID: 18223542 [PubMed - indexed for MEDLINE]Related articles

The role of salt in hypertension: the complexity seems to become clearer.

Frohlich ED.

Nat Clin Pract Cardiovasc Med. 2008 Jan;5(1):2-3. No abstract available. PMID: 18073713 [PubMed - indexed for MEDLINE]Related articles

AT1 receptor antagonism attenuates target organ effects of salt excess in SHRs without affecting pressure.

Varagic J, Frohlich ED, Susic D, Ahn J, Matavelli L, López B, Díez J.

Am J Physiol Heart Circ Physiol. 2008 Feb;294(2):H853-8. Epub 2007 Nov 30.PMID: 18055516 [PubMed - indexed for MEDLINE]Related articlesFree article

The metabolic syndrome: there's little that's new under the sun!

Frohlich ED.

J Cardiometab Syndr. 2006 Fall;1(5):293-4. No abstract available. PMID: 17679798 [PubMed - indexed for MEDLINE]Related articles

The salt conundrum: a hypothesis.

Frohlich ED.

Hypertension. 2007 Jul;50(1):161-6. Epub 2007 Apr 30. Review. No abstract available. PMID: 17470717 [PubMed - indexed for MEDLINE]Related articlesFree article

Analogy of cardiac and renal complications in essential hypertension and aged SHR or L-NAME/SHR.

Zhou X, Frohlich ED.

Med Chem. 2007 Jan;3(1):61-5. Review.PMID: 17266625 [PubMed - indexed for MEDLINE]Related articles

Blood pressure, large arteries and atherosclerosis.

Frohlich ED, Susic D.

Adv Cardiol. 2007;44:117-24. Review.PMID: 17075202 [PubMed - indexed for MEDLINE]Related articles

Cardiovascular effects of nonproteolytic activation of prorenin.

Susic D, Lippton H, Knight M, Frohlich ED.

Hypertension. 2006 Dec;48(6):e113; author reply e114. Epub 2006 Oct 16. No abstract available. PMID: 17043161 [PubMed - indexed for MEDLINE]Related articlesFree article

Salt loading produces severe renal hemodynamic dysfunction independent of arterial pressure in spontaneously hypertensive rats.

Matavelli LC, Zhou X, Varagic J, Susic D, Frohlich ED.

Am J Physiol Heart Circ Physiol. 2007 Feb;292(2):H814-9. Epub 2006 Sep 22.PMID: 16997890 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term mineralocorticoid receptor blockade reduces fibrosis and improves cardiac performance and coronary hemodynamics in elderly SHR.

Susic D, Varagic J, Ahn J, Matavelli L, Frohlich ED.

Am J Physiol Heart Circ Physiol. 2007 Jan;292(1):H175-9. Epub 2006 Aug 11.PMID: 16905598 [PubMed - indexed for MEDLINE]Related articlesFree article

Improvements in clinical outcomes with the use of angiotensin-converting enzyme inhibitors: cross-fertilization between clinical and basic investigation.

Pfeffer MA, Frohlich ED.

Am J Physiol Heart Circ Physiol. 2006 Nov;291(5):H2021-5. Epub 2006 Jul 7.PMID: 16829641 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypertensive renal vascular disease and cardiovascular endpoints.

Matavelli LC, Zhou X, Frohlich ED.

Curr Opin Cardiol. 2006 Jul;21(4):305-9. Review.PMID: 16755198 [PubMed - indexed for MEDLINE]Related articles

Overview for the hypertension issue of Current Opinion in Cardiology.

Frohlich ED.

Curr Opin Cardiol. 2006 Jul;21(4):265-7. No abstract available. PMID: 16755192 [PubMed - indexed for MEDLINE]Related articles

Uric acid: its relationship to renal hemodynamics and the renal renin-angiotensin system.

Zhou X, Matavelli L, Frohlich ED.

Curr Hypertens Rep. 2006 May;8(2):120-4. Review.PMID: 16672144 [PubMed - indexed for MEDLINE]Related articles

Myocardial fibrosis, impaired coronary hemodynamics, and biventricular dysfunction in salt-loaded SHR.

Varagic J, Frohlich ED, Díez J, Susic D, Ahn J, González A, López B.

Am J Physiol Heart Circ Physiol. 2006 Apr;290(4):H1503-9. Epub 2005 Nov 18.PMID: 16299266 [PubMed - indexed for MEDLINE]Related articlesFree article

Guidelines on hypertension in 2005: a commentary.

Frohlich ED.

Nat Clin Pract Cardiovasc Med. 2005 Jun;2(6):269. No abstract available. PMID: 16265511 [PubMed - indexed for MEDLINE]Related articles

The role of sodium in hypertension is more complex than simply elevating arterial pressure.

Frohlich ED, Varagic J.

Nat Clin Pract Cardiovasc Med. 2004 Nov;1(1):24-30. Review.PMID: 16265256 [PubMed - indexed for MEDLINE]Related articles

Hurricane Katrina. Aftershocks.

Frohlich ED.

N Engl J Med. 2005 Oct 13;353(15):1545. No abstract available. PMID: 16221773 [PubMed - indexed for MEDLINE]Related articles

Beneficial cardiovascular actions of eplerenone in the spontaneously hypertensive rat.

Susic D, Varagic J, Ahn J, Matavelli LC, Frohlich ED.

J Cardiovasc Pharmacol Ther. 2005 Sep;10(3):197-203.PMID: 16211209 [PubMed - indexed for MEDLINE]Related articles

Sodium directly impairs target organ function in hypertension.

Frohlich ED, Varagic J.

Curr Opin Cardiol. 2005 Sep;20(5):424-9. Review.PMID: 16093762 [PubMed - indexed for MEDLINE]Related articles

Physiologic evidence of renoprotection by antihypertensive therapy.

Zhou X, Frohlich ED.

Curr Opin Cardiol. 2005 Jul;20(4):290-5. Review.PMID: 15956825 [PubMed - indexed for MEDLINE]Related articles

Recent advances in hypertension, stroke, and cardiorenal disease.

Frohlich ED.

Curr Opin Cardiol. 2005 Jul;20(4):258-63. Review. No abstract available. PMID: 15956820 [PubMed - indexed for MEDLINE]Related articles

Superiority of combination of thiazide with angiotensin-converting enzyme inhibitor or AT1-receptor blocker over thiazide alone on renoprotection in L-NAME/SHR.

Zhou X, Matavelli LC, Ono H, Frohlich ED.

Am J Physiol Renal Physiol. 2005 Oct;289(4):F871-9. Epub 2005 May 17.PMID: 15900021 [PubMed - indexed for MEDLINE]Related articlesFree article

Validation of echocardiographic and Doppler indexes of left ventricular relaxation in adult hypertensive and normotensive rats.

Slama M, Ahn J, Peltier M, Maizel J, Chemla D, Varagic J, Susic D, Tribouilloy C, Frohlich ED.

Am J Physiol Heart Circ Physiol. 2005 Sep;289(3):H1131-6. Epub 2005 Apr 29.PMID: 15863455 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential effects of antihypertensive drugs on renal and glomerular hemodynamics and injury in the chronic nitric-oxide-suppressed rat.

Zhou X, Frohlich ED.

Am J Nephrol. 2005 Mar-Apr;25(2):138-52. Epub 2005 Apr 22.PMID: 15855741 [PubMed - indexed for MEDLINE]Related articles

Subliminal editorial conundra confounding publication of multicenter trials.

Frohlich ED, Pepine CJ.

Am J Cardiol. 2004 Nov 15;94(10):1268-9. No abstract available. PMID: 15541242 [PubMed - indexed for MEDLINE]Related articles

Seasonal variations in blood pressure.

Frohlich ED.

Am J Geriatr Cardiol. 2004 Sep-Oct;13(5):274-5. No abstract available. PMID: 15365291 [PubMed - indexed for MEDLINE]Related articles

Crosslink breakers: a new approach to cardiovascular therapy.

Susic D, Varagic J, Ahn J, Frohlich ED.

Curr Opin Cardiol. 2004 Jul;19(4):336-40. Review.PMID: 15218393 [PubMed - indexed for MEDLINE]Related articles

Left ventricular hypertrophy: a "factor of risk": mass is reversible, but is the risk?

Frohlich ED.

J Am Coll Cardiol. 2004 Jun 16;43(12):2216-8. No abstract available. PMID: 15193682 [PubMed - indexed for MEDLINE]Related articles

Obesity and suppressed B-type natriuretic peptide levels in heart failure.

Mehra MR, Uber PA, Park MH, Scott RL, Ventura HO, Harris BC, Frohlich ED.

J Am Coll Cardiol. 2004 May 5;43(9):1590-5.PMID: 15120816 [PubMed - indexed for MEDLINE]Related articles

Cardiovascular and renal effects of a collagen cross-link breaker (ALT 711) in adult and aged spontaneously hypertensive rats.

Susic D, Varagic J, Ahn J, Frohlich ED.

Am J Hypertens. 2004 Apr;17(4):328-33.PMID: 15062886 [PubMed - indexed for MEDLINE]Related articles

Cardiac structural and functional responses to salt loading in SHR.

Ahn J, Varagic J, Slama M, Susic D, Frohlich ED.

Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H767-72. Epub 2004 Apr 1.PMID: 15059772 [PubMed - indexed for MEDLINE]Related articlesFree article

Collagen cross-link breakers: a beginning of a new era in the treatment of cardiovascular changes associated with aging, diabetes, and hypertension.

Susic D, Varagic J, Ahn J, Frohlich ED.

Curr Drug Targets Cardiovasc Haematol Disord. 2004 Mar;4(1):97-101. Review.PMID: 15032654 [PubMed - indexed for MEDLINE]Related articles

Aldosterone antagonism ameliorates proteinuria and nephrosclerosis independent of glomerular dynamics in L-NAME/SHR model.

Zhou X, Ono H, Ono Y, Frohlich ED.

Am J Nephrol. 2004 Mar-Apr;24(2):242-9. Epub 2004 Mar 17.PMID: 15031627 [PubMed - indexed for MEDLINE]Related articles

Target organ involvement in hypertension: a realistic promise of prevention and reversal.

Frohlich ED.

Med Clin North Am. 2004 Jan;88(1):209-21. Review.PMID: 14871060 [PubMed - indexed for MEDLINE]Related articles