PubMed

Histone deacetylase inhibitor romidepsin enhances anti-tumor effect of erlotinib in non-small cell lung cancer (NSCLC) cell lines.

Zhang W, Peyton M, Xie Y, Soh J, Minna JD, Gazdar AF, Frenkel EP.

J Thorac Oncol. 2009 Feb;4(2):161-6.PMID: 19179890 [PubMed - indexed for MEDLINE]Related articlesFree article

Phase I dose escalation study with irinotecan, capecitabine, epirubicin, and granulocyte colony-stimulating factor support for patients with solid malignancies.

Becerra CR, Verma UN, Tran HT, Tavana D, Williams NS, Frenkel EP.

Am J Clin Oncol. 2008 Jun;31(3):219-25.PMID: 18525298 [PubMed - indexed for MEDLINE]Related articles

Clopidogrel anti-platelet effect: an evaluation by optical aggregometry, impedance aggregometry, and the platelet function analyzer (PFA-100).

Dyszkiewicz-Korpanty A, Olteanu H, Frenkel EP, Sarode R.

Platelets. 2007 Nov;18(7):491-6.PMID: 17852774 [PubMed - indexed for MEDLINE]Related articles

Acquired platelet dysfunction.

Shen YM, Frenkel EP.

Hematol Oncol Clin North Am. 2007 Aug;21(4):647-61, vi. Review.PMID: 17666283 [PubMed - indexed for MEDLINE]Related articles

Comparison of a rapid platelet function assay--Verify Now Aspirin--with whole blood impedance aggregometry for the detection of aspirin resistance.

Dyszkiewicz-Korpanty AM, Kim A, Burner JD, Frenkel EP, Sarode R.

Thromb Res. 2007;120(4):485-8. Epub 2007 Jan 16. No abstract available. PMID: 17229458 [PubMed - indexed for MEDLINE]Related articles

Efficacy of sequential treatment of HCT116 colon cancer monolayers and xenografts with docetaxel, flavopiridol, and 5-fluorouracil.

Guo J, Zhou AW, Fu YC, Verma UN, Tripathy D, Frenkel EP, Becerra CR.

Acta Pharmacol Sin. 2006 Oct;27(10):1375-81.PMID: 17007746 [PubMed - indexed for MEDLINE]Related articlesFree article

Methylation of apoptosis related genes in the pathogenesis and prognosis of prostate cancer.

Suzuki M, Shigematsu H, Shivapurkar N, Reddy J, Miyajima K, Takahashi T, Gazdar AF, Frenkel EP.

Cancer Lett. 2006 Oct 28;242(2):222-30. Epub 2006 Feb 3.PMID: 16458425 [PubMed - indexed for MEDLINE]Related articles

Poor correlation of supratherapeutic international normalised ratio and vitamin K-dependent procoagulant factor levels during warfarin therapy.

Sarode R, Rawal A, Lee R, Shen YM, Frenkel EP.

Br J Haematol. 2006 Mar;132(5):604-7.PMID: 16445834 [PubMed - indexed for MEDLINE]Related articles

DNA methylation-associated inactivation of TGFbeta-related genes DRM/Gremlin, RUNX3, and HPP1 in human cancers.

Suzuki M, Shigematsu H, Shames DS, Sunaga N, Takahashi T, Shivapurkar N, Iizasa T, Frenkel EP, Minna JD, Fujisawa T, Gazdar AF.

Br J Cancer. 2005 Oct 31;93(9):1029-37.PMID: 16234815 [PubMed - indexed for MEDLINE]Related articlesFree article

IkappaB kinase alpha regulates subcellular distribution and turnover of cyclin D1 by phosphorylation.

Kwak YT, Li R, Becerra CR, Tripathy D, Frenkel EP, Verma UN.

J Biol Chem. 2005 Oct 7;280(40):33945-52. Epub 2005 Aug 15. Erratum in: J Biol Chem. 2005 Nov 18;280(46):38888. PMID: 16103118 [PubMed - indexed for MEDLINE]Related articlesFree article

Approach to the assessment of platelet function: comparison between optical-based platelet-rich plasma and impedance-based whole blood platelet aggregation methods.

Dyszkiewicz-Korpanty AM, Frenkel EP, Sarode R.

Clin Appl Thromb Hemost. 2005 Jan;11(1):25-35.PMID: 15678270 [PubMed - indexed for MEDLINE]Related articles

The direct thrombin inhibitors: their role and use for rational anticoagulation.

Frenkel EP, Shen YM, Haley BB.

Hematol Oncol Clin North Am. 2005 Feb;19(1):119-45, vi-vii. Review.PMID: 15639111 [PubMed - indexed for MEDLINE]Related articles

Unfractionated heparin, low molecular weight heparins, and pentasaccharide: basic mechanism of actions, pharmacology, and clinical use.

Bick RL, Frenkel EP, Walenga J, Fareed J, Hoppensteadt DA.

Hematol Oncol Clin North Am. 2005 Feb;19(1):1-51, v. Review.PMID: 15639107 [PubMed - indexed for MEDLINE]Related articles

Circulating tumor cells in patients with breast cancer dormancy.

Meng S, Tripathy D, Frenkel EP, Shete S, Naftalis EZ, Huth JF, Beitsch PD, Leitch M, Hoover S, Euhus D, Haley B, Morrison L, Fleming TP, Herlyn D, Terstappen LW, Fehm T, Tucker TF, Lane N, Wang J, Uhr JW.

Clin Cancer Res. 2004 Dec 15;10(24):8152-62.PMID: 15623589 [PubMed - indexed for MEDLINE]Related articlesFree article

MIB1 labeling index as an indicator of chemoresponse in carcinoma of the breast.

Sharma S, Saboorian HM, Frawley WH, Frenkel EP, Haley BB, Ashfaq R.

Appl Immunohistochem Mol Morphol. 2004 Dec;12(4):290-5.PMID: 15536327 [PubMed - indexed for MEDLINE]Related articles

PEGylation confers greatly extended half-life and attenuated immunogenicity to recombinant methioninase in primates.

Yang Z, Wang J, Lu Q, Xu J, Kobayashi Y, Takakura T, Takimoto A, Yoshioka T, Lian C, Chen C, Zhang D, Zhang Y, Li S, Sun X, Tan Y, Yagi S, Frenkel EP, Hoffman RM.

Cancer Res. 2004 Sep 15;64(18):6673-8.PMID: 15374983 [PubMed - indexed for MEDLINE]Related articlesFree article

Circulating half-life of PEGylated recombinant methioninase holoenzyme is highly dose dependent on cofactor pyridoxal-5'-phosphate.

Yang Z, Sun X, Li S, Tan Y, Wang X, Zhang N, Yagi S, Takakura T, Kobayashi Y, Takimoto A, Yoshioka T, Suginaka A, Frenkel EP, Hoffman RM.

Cancer Res. 2004 Aug 15;64(16):5775-8.PMID: 15313919 [PubMed - indexed for MEDLINE]Related articlesFree article

Thrombosis and a hypercoagulable state in HIV-infected patients.

Shen YM, Frenkel EP.

Clin Appl Thromb Hemost. 2004 Jul;10(3):277-80. Review.PMID: 15247986 [PubMed - indexed for MEDLINE]Related articles

Enhanced chemosensitivity to irinotecan by RNA interference-mediated down-regulation of the nuclear factor-kappaB p65 subunit.

Guo J, Verma UN, Gaynor RB, Frenkel EP, Becerra CR.

Clin Cancer Res. 2004 May 15;10(10):3333-41.PMID: 15161687 [PubMed - indexed for MEDLINE]Related articlesFree article

Pharmacokinetics, methionine depletion, and antigenicity of recombinant methioninase in primates.

Yang Z, Wang J, Yoshioka T, Li B, Lu Q, Li S, Sun X, Tan Y, Yagi S, Frenkel EP, Hoffman RM.

Clin Cancer Res. 2004 Mar 15;10(6):2131-8.PMID: 15041734 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular detection of noninvasive and invasive bladder tumor tissues and exfoliated cells by aberrant promoter methylation of laminin-5 encoding genes.

Sathyanarayana UG, Maruyama R, Padar A, Suzuki M, Bondaruk J, Sagalowsky A, Minna JD, Frenkel EP, Grossman HB, Czerniak B, Gazdar AF.

Cancer Res. 2004 Feb 15;64(4):1425-30.PMID: 14973053 [PubMed - indexed for MEDLINE]Related articlesFree article

Aberrant promoter methylation of laminin-5-encoding genes in prostate cancers and its relationship to clinicopathological features.

Sathyanarayana UG, Padar A, Suzuki M, Maruyama R, Shigematsu H, Hsieh JT, Frenkel EP, Gazdar AF.

Clin Cancer Res. 2003 Dec 15;9(17):6395-400.PMID: 14695140 [PubMed - indexed for MEDLINE]Related articlesFree article

In vivo efficacy of recombinant methioninase is enhanced by the combination of polyethylene glycol conjugation and pyridoxal 5'-phosphate supplementation.

Sun X, Yang Z, Li S, Tan Y, Zhang N, Wang X, Yagi S, Yoshioka T, Takimoto A, Mitsushima K, Suginaka A, Frenkel EP, Hoffman RM.

Cancer Res. 2003 Dec 1;63(23):8377-83.PMID: 14678999 [PubMed - indexed for MEDLINE]Related articlesFree article

Inactivation of cyclin D2 gene in prostate cancers by aberrant promoter methylation.

Padar A, Sathyanarayana UG, Suzuki M, Maruyama R, Hsieh JT, Frenkel EP, Minna JD, Gazdar AF.

Clin Cancer Res. 2003 Oct 15;9(13):4730-4.PMID: 14581343 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased toxicity and lack of efficacy of Rofecoxib in combination with chemotherapy for treatment of metastatic colorectal cancer: A phase II study.

Becerra CR, Frenkel EP, Ashfaq R, Gaynor RB.

Int J Cancer. 2003 Jul 20;105(6):868-72.PMID: 12767075 [PubMed - indexed for MEDLINE]Related articles

Heparin-induced thrombocytopenia, paradoxical thromboembolism, and other adverse effects of heparin-type therapy.

Walenga JM, Frenkel EP, Bick RL.

Hematol Oncol Clin North Am. 2003 Feb;17(1):259-82, viii-ix. Review.PMID: 12627671 [PubMed - indexed for MEDLINE]Related articles

Hyperhomocysteinemia and thrombosis.

Lee R, Frenkel EP.

Hematol Oncol Clin North Am. 2003 Feb;17(1):85-102. Review.PMID: 12627664 [PubMed - indexed for MEDLINE]Related articles

Sticky platelet syndrome and thrombocythemia.

Frenkel EP, Mammen EF.

Hematol Oncol Clin North Am. 2003 Feb;17(1):63-83. Review.PMID: 12627663 [PubMed - indexed for MEDLINE]Related articles

Cobalamin profiles in patients after urinary diversion.

Sagalowsky AI, Frenkel EP.

J Urol. 2002 Apr;167(4):1696-700.PMID: 11912390 [PubMed - indexed for MEDLINE]Related articles

Aneusomy 17 in breast cancer: its role in HER-2/neu protein expression and implication for clinical assessment of HER-2/neu status.

Wang S, Hossein Saboorian M, Frenkel EP, Haley BB, Siddiqui MT, Gokaslan S, Hynan L, Ashfaq R.

Mod Pathol. 2002 Feb;15(2):137-45.PMID: 11850542 [PubMed - indexed for MEDLINE]Related articlesFree article

Aberrant promoter methylation profile of prostate cancers and its relationship to clinicopathological features.

Maruyama R, Toyooka S, Toyooka KO, Virmani AK, Zöchbauer-Müller S, Farinas AJ, Minna JD, McConnell J, Frenkel EP, Gazdar AF.

Clin Cancer Res. 2002 Feb;8(2):514-9.PMID: 11839671 [PubMed - indexed for MEDLINE]Related articlesFree article

Enhanced transgene expression in androgen independent prostate cancer gene therapy by taxane chemotherapeutic agents.

Li Y, Okegawa T, Lombardi DP, Frenkel EP, Hsieh JT.

J Urol. 2002 Jan;167(1):339-46.PMID: 11743353 [PubMed - indexed for MEDLINE]Related articles

Assessment of HER-2/neu status in breast cancer. Automated Cellular Imaging System (ACIS)-assisted quantitation of immunohistochemical assay achieves high accuracy in comparison with fluorescence in situ hybridization assay as the standard.

Wang S, Saboorian MH, Frenkel EP, Haley BB, Siddiqui MT, Gokaslan S, Wians FH Jr, Hynan L, Ashfaq R.

Am J Clin Pathol. 2001 Oct;116(4):495-503.PMID: 11601134 [PubMed - indexed for MEDLINE]Related articlesFree article

Synergy between methionine stress and chemotherapy in the treatment of brain tumor xenografts in athymic mice.

Kokkinakis DM, Hoffman RM, Frenkel EP, Wick JB, Han Q, Xu M, Tan Y, Schold SC.

Cancer Res. 2001 May 15;61(10):4017-23.PMID: 11358820 [PubMed - indexed for MEDLINE]Related articlesFree article

Topoisomerase I inhibition with topotecan: pharmacologic and clinical issues.

Arun B, Frenkel EP.

Expert Opin Pharmacother. 2001 Mar;2(3):491-505. Review.PMID: 11336601 [PubMed - indexed for MEDLINE]Related articles

Phase I study of paclitaxel given by seven-week continuous infusion concurrent with radiation therapy for locally advanced squamous cell carcinoma of the head and neck.

Rosenthal DI, Lee JH, Sinard R, Yardley DA, Machtay M, Rosen DM, Egorin MJ, Weber RS, Weinstein GS, Chalian AA, Miller LK, Frenkel EP, Carbone DP.

J Clin Oncol. 2001 Mar 1;19(5):1363-73.PMID: 11230480 [PubMed - indexed for MEDLINE]Related articles

Reversible renal toxicity resulting from high single doses of the new radiosensitizer gadolinium texaphyrin.

Rosenthal DI, Becerra CR, Toto RD, Carbone DP, Frenkel EP.

Am J Clin Oncol. 2000 Dec;23(6):593-8.PMID: 11202804 [PubMed - indexed for MEDLINE]Related articles

L-asparaginase-provoked seizures as singular expression of central nervous toxicity.

Hamdan MY, Frenkel EP, Bick R.

Clin Appl Thromb Hemost. 2000 Oct;6(4):234-8.PMID: 11030530 [PubMed - indexed for MEDLINE]Related articles

Clinical and laboratory features and sequelae of deficiency of folic acid (folate) and vitamin B12 (cobalamin) in pregnancy and gynecology.

Frenkel EP, Yardley DA.

Hematol Oncol Clin North Am. 2000 Oct;14(5):1079-100, viii. Review.PMID: 11005035 [PubMed - indexed for MEDLINE]Related articles

Clinical aspects of heparin-induced thrombocytopenia and thrombosis and other side effects of heparin therapy.

Bick RL, Frenkel EP.

Clin Appl Thromb Hemost. 1999 Oct;5 Suppl 1:S7-15. Review.PMID: 10726030 [PubMed - indexed for MEDLINE]Related articles

Disseminated intravascular coagulation. clinical and pathophysiological mechanisms and manifestations.

Bick RL, Arun B, Frenkel EP.

Haemostasis. 1999;29(2-3):111-34. Review.PMID: 10629392 [PubMed - indexed for MEDLINE]Related articles

Antiphospholipid-thrombosis syndromes.

Bick RL, Arun B, Frenkel EP.

Haemostasis. 1999;29(2-3):100-10. Review.PMID: 10629391 [PubMed - indexed for MEDLINE]Related articles

Prothrombin G20210A gene mutation, heparin cofactor II defects, primary (essential) thrombocythemia, and thrombohemorrhagic manifestations.

Frenkel EP, Bick RL.

Semin Thromb Hemost. 1999;25(4):375-86. Review.PMID: 10548071 [PubMed - indexed for MEDLINE]Related articles

A phase I single-dose trial of gadolinium texaphyrin (Gd-Tex), a tumor selective radiation sensitizer detectable by magnetic resonance imaging.

Rosenthal DI, Nurenberg P, Becerra CR, Frenkel EP, Carbone DP, Lum BL, Miller R, Engel J, Young S, Miles D, Renschler MF.

Clin Cancer Res. 1999 Apr;5(4):739-45.PMID: 10213207 [PubMed - indexed for MEDLINE]Related articlesFree article

Issues of thrombosis and hemorrhagic events in patients with cancer.

Frenkel EP, Bick R.

In Vivo. 1998 Nov-Dec;12(6):625-8. Review.PMID: 9891225 [PubMed - indexed for MEDLINE]Related articles

Seven-week continuous-infusion paclitaxel with concurrent radiotherapy for locally advanced head and neck squamous cell cancer: a phase I study.

Rosenthal DI, Sinard RJ, Okani O, Corak J, Kavanaugh D, Kamen B, Vuitch FM, Gazdar AF, Griener J, Frenkel EP, Carbone DP.

Semin Oncol. 1997 Dec;24(6 Suppl 19):S19-67-S19-71.PMID: 9427270 [PubMed - indexed for MEDLINE]Related articles

The role of chemotherapy in head and neck cancer.

Hughes RS, Frenkel EP.

Am J Clin Oncol. 1997 Oct;20(5):449-61. Review.PMID: 9345327 [PubMed - indexed for MEDLINE]Related articles

Thrombosis and hemorrhage in oncology patients.

Bick RL, Strauss JF, Frenkel EP.

Hematol Oncol Clin North Am. 1996 Aug;10(4):875-907. Review.PMID: 8811307 [PubMed - indexed for MEDLINE]Related articles

Anemia of malignancy.

Frenkel EP, Bick RL, Rutherford CJ.

Hematol Oncol Clin North Am. 1996 Aug;10(4):861-73. Review.PMID: 8811306 [PubMed - indexed for MEDLINE]Related articles

The effect of running on serum and red cell ferritin. A longitudinal comparison.

Balaban EP, Snell P, Stray-Gundersen J, Frenkel EP.

Int J Sports Med. 1995 Jul;16(5):278-82.PMID: 7558522 [PubMed - indexed for MEDLINE]Related articles