PubMed

Intracranial glioblastoma models in preclinical neuro-oncology: neuropathological characterization and tumor progression.

Candolfi M, Curtin JF, Nichols WS, Muhammad AG, King GD, Pluhar GE, McNiel EA, Ohlfest JR, Freese AB, Moore PF, Lerner J, Lowenstein PR, Castro MG.

J Neurooncol. 2007 Nov;85(2):133-48. Epub 2007 Sep 15.PMID: 17874037 [PubMed - indexed for MEDLINE]Related articlesFree article

Efficacy of nonviral gene transfer in the canine brain.

Oh S, Pluhar GE, McNeil EA, Kroeger KM, Liu C, Castro MG, Lowenstein PR, Freese A, Ohlfest JR.

J Neurosurg. 2007 Jul;107(1):136-44.PMID: 17639883 [PubMed - indexed for MEDLINE]Related articlesFree article

Optimization of adenoviral vector-mediated transgene expression in the canine brain in vivo, and in canine glioma cells in vitro.

Candolfi M, Pluhar GE, Kroeger K, Puntel M, Curtin J, Barcia C, Muhammad AK, Xiong W, Liu C, Mondkar S, Kuoy W, Kang T, McNeil EA, Freese AB, Ohlfest JR, Moore P, Palmer D, Ng P, Young JD, Lowenstein PR, Castro MG.

Neuro Oncol. 2007 Jul;9(3):245-58. Epub 2007 May 23.PMID: 17522335 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenoviral-mediated gene transfer into the canine brain in vivo.

Candolfi M, Kroeger KM, Pluhar GE, Bergeron J, Puntel M, Curtin JF, McNiel EA, Freese AB, Ohlfest JR, Moore P, Lowenstein PR, Castro MG.

Neurosurgery. 2007 Jan;60(1):167-77; discussion 178.PMID: 17228266 [PubMed - indexed for MEDLINE]Related articlesFree article

Natural history of Canavan disease revealed by proton magnetic resonance spectroscopy (1H-MRS) and diffusion-weighted MRI.

Janson CG, McPhee SW, Francis J, Shera D, Assadi M, Freese A, Hurh P, Haselgrove J, Wang DJ, Bilaniuk L, Leone P.

Neuropediatrics. 2006 Aug;37(4):209-21.PMID: 17177147 [PubMed - indexed for MEDLINE]Related articles

Immune responses to AAV in a phase I study for Canavan disease.

McPhee SW, Janson CG, Li C, Samulski RJ, Camp AS, Francis J, Shera D, Lioutermann L, Feely M, Freese A, Leone P.

J Gene Med. 2006 May;8(5):577-88.PMID: 16532510 [PubMed - indexed for MEDLINE]Related articles

Nonviral vectors for cancer gene therapy: prospects for integrating vectors and combination therapies.

Ohlfest JR, Freese AB, Largaespada DA.

Curr Gene Ther. 2005 Dec;5(6):629-41. Review.PMID: 16457652 [PubMed - indexed for MEDLINE]Related articles

Mild-onset presentation of Canavan's disease associated with novel G212A point mutation in aspartoacylase gene.

Janson CG, Kolodny EH, Zeng BJ, Raghavan S, Pastores G, Torres P, Assadi M, McPhee S, Goldfarb O, Saslow B, Freese A, Wang DJ, Bilaniuk L, Shera D, Leone P.

Ann Neurol. 2006 Feb;59(2):428-31.PMID: 16437572 [PubMed - indexed for MEDLINE]Related articles

Emerging concepts in glioma biology: implications for clinical protocols and rational treatment strategies.

Wiesner SM, Freese A, Ohlfest JR.

Neurosurg Focus. 2005 Oct 15;19(4):E3. Review.PMID: 16241105 [PubMed - indexed for MEDLINE]Related articles

Combinatorial antiangiogenic gene therapy by nonviral gene transfer using the sleeping beauty transposon causes tumor regression and improves survival in mice bearing intracranial human glioblastoma.

Ohlfest JR, Demorest ZL, Motooka Y, Vengco I, Oh S, Chen E, Scappaticci FA, Saplis RJ, Ekker SC, Low WC, Freese AB, Largaespada DA.

Mol Ther. 2005 Nov;12(5):778-88. Epub 2005 Sep 16.PMID: 16150649 [PubMed - indexed for MEDLINE]Related articles

Effects of AAV-2-mediated aspartoacylase gene transfer in the tremor rat model of Canavan disease.

McPhee SW, Francis J, Janson CG, Serikawa T, Hyland K, Ong EO, Raghavan SS, Freese A, Leone P.

Brain Res Mol Brain Res. 2005 Apr 27;135(1-2):112-21.PMID: 15857674 [PubMed - indexed for MEDLINE]Related articles

Effect of altering titer, serotype, and promoter in recombinant adenoassociate virus gene therapy expression of spinal cord neurons and astrocytes.

Harrop JS, Poulsen DJ, Xiao W, Freese A, During MJ.

Spine (Phila Pa 1976). 2004 Dec 15;29(24):2787-92.PMID: 15599280 [PubMed - indexed for MEDLINE]Related articles

Clinical protocol. Gene therapy of Canavan disease: AAV-2 vector for neurosurgical delivery of aspartoacylase gene (ASPA) to the human brain.

Janson C, McPhee S, Bilaniuk L, Haselgrove J, Testaiuti M, Freese A, Wang DJ, Shera D, Hurh P, Rupin J, Saslow E, Goldfarb O, Goldberg M, Larijani G, Sharrar W, Liouterman L, Camp A, Kolodny E, Samulski J, Leone P.

Hum Gene Ther. 2002 Jul 20;13(11):1391-412.PMID: 12162821 [PubMed - indexed for MEDLINE]Related articles

HLA-B7 beta-pleated sheet-derived synthetic peptides are immunodominant T-cell epitopes regulating alloresponses.

Freese A, Zavazava N.

Blood. 2002 May 1;99(9):3286-92.PMID: 11964295 [PubMed - indexed for MEDLINE]Related articlesFree article

Viral-based gene transfer to the mammalian CNS for functional genomic studies.

Janson CG, McPhee SW, Leone P, Freese A, During MJ.

Trends Neurosci. 2001 Dec;24(12):706-12. Review. Erratum in: Trends Neurosci 2002 Jan;25(1):59. PMID: 11718875 [PubMed - indexed for MEDLINE]Related articles

Aspartoacylase gene transfer to the mammalian central nervous system with therapeutic implications for Canavan disease.

Leone P, Janson CG, Bilaniuk L, Wang Z, Sorgi F, Huang L, Matalon R, Kaul R, Zeng Z, Freese A, McPhee SW, Mee E, During MJ.

Ann Neurol. 2000 Jul;48(1):27-38. Erratum in: Ann Neurol 2000 Sep;48(3):398. Bilianuk L [corrected to Bilaniuk L]. PMID: 10894213 [PubMed - indexed for MEDLINE]Related articles

Oral feeding of an immunodominant MHC donor-derived synthetic class I peptide prolongs graft survival of heterotopic cardiac allografts in a high-responder rat strain combination.

Zavazava N, Fändrich F, Zhu X, Freese A, Behrens D, Yoo-Ott KA.

J Leukoc Biol. 2000 Jun;67(6):793-800.PMID: 10857851 [PubMed - indexed for MEDLINE]Related articlesFree article

Multi-site partitioned delivery of human tyrosine hydroxylase gene with phenotypic recovery in Parkinsonian rats.

Leone P, McPhee SW, Janson CG, Davidson BL, Freese A, During MJ.

Neuroreport. 2000 Apr 27;11(6):1145-51.PMID: 10817582 [PubMed - indexed for MEDLINE]Related articles

Restorative gene therapy approaches to Parkinson's disease.

Freese A.

Med Clin North Am. 1999 Mar;83(2):537-48. Review.PMID: 10093593 [PubMed - indexed for MEDLINE]Related articles

In vivo expression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vector.

During MJ, Samulski RJ, Elsworth JD, Kaplitt MG, Leone P, Xiao X, Li J, Freese A, Taylor JR, Roth RH, Sladek JR Jr, O'Malley KL, Redmond DE Jr.

Gene Ther. 1998 Jun;5(6):820-7.PMID: 9747462 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenovirus vector-mediated gene transfer into human epileptogenic brain slices: prospects for gene therapy in epilepsy.

O'Connor WM, Davidson BL, Kaplitt MG, Abbey MV, During MJ, Leone P, Langer D, O'Connor MJ, Freese A.

Exp Neurol. 1997 Nov;148(1):167-78.PMID: 9398459 [PubMed - indexed for MEDLINE]Related articles

Analysis of harvest morbidity and radiographic outcome using autograft for anterior cervical fusion.

Schnee CL, Freese A, Weil RJ, Marcotte PJ.

Spine (Phila Pa 1976). 1997 Oct 1;22(19):2222-7.PMID: 9346142 [PubMed - indexed for MEDLINE]Related articles

Direct gene transfer into human epileptogenic hippocampal tissue with an adeno-associated virus vector: implications for a gene therapy approach to epilepsy.

Freese A, Kaplitt MG, O'Connor WM, Abbey M, Langer D, Leone P, O'Connor MJ, During MJ.

Epilepsia. 1997 Jul;38(7):759-66.PMID: 9579902 [PubMed - indexed for MEDLINE]Related articles

Parkinson's disease: the case for novel treatment strategies.

Stern MB, Freese A.

Exp Neurol. 1997 Mar;144(1):2-3.PMID: 9126142 [PubMed - indexed for MEDLINE]Related articles

Functional and biosynthetic aspects of sialic acid diversity.

Schauer R, de Freese A, Gollub M, Iwersen M, Kelm S, Reuter G, Schlenzka W, Vandamme-Feldhaus V, Shaw L.

Indian J Biochem Biophys. 1997 Feb-Apr;34(1-2):131-41.PMID: 9343941 [PubMed - indexed for MEDLINE]Related articles

MR of thoracic cord compression caused by epidural extramedullary hematopoiesis in myelodysplastic syndrome.

Dibbern DA Jr, Loevner LA, Lieberman AP, Salhany KE, Freese A, Marcotte PJ.

AJNR Am J Neuroradiol. 1997 Feb;18(2):363-6.PMID: 9111677 [PubMed - indexed for MEDLINE]Related articlesFree article

Further characterization and in situ localization of chain-like aggregates of the gliding bacteria Myxococcus fulvus and Myxococcus xanthus.

Freese A, Reichenbach H, Lünsdorf H.

J Bacteriol. 1997 Feb;179(4):1246-52.PMID: 9023208 [PubMed - indexed for MEDLINE]Related articlesFree article

Outcome analysis for adults with spondylolisthesis treated with posterolateral fusion and transpedicular screw fixation.

Schnee CL, Freese A, Ansell LV.

J Neurosurg. 1997 Jan;86(1):56-63.PMID: 8988082 [PubMed - indexed for MEDLINE]Related articles

Prospects for gene therapy in Parkinson's disease.

Freese A, Stern M, Kaplitt MG, O'Connor WM, Abbey MV, O'Connor MJ, During MJ.

Mov Disord. 1996 Sep;11(5):469-88. Review.PMID: 8866488 [PubMed - indexed for MEDLINE]Related articles

Transfection of human lactotroph adenoma cells with an adenovirus vector expressing tyrosine hydroxylase decreases prolactin release.

Freese A, During MJ, Davidson BL, Gennarelli TA, Kaplitt MG, Flamm ES, Snyder PJ.

J Clin Endocrinol Metab. 1996 Jun;81(6):2401-4.PMID: 8964885 [PubMed - indexed for MEDLINE]Related articles

Subvocal speech, reading rate, and comprehension.

Freese AR.

Percept Mot Skills. 1996 Jun;82(3 Pt 2):1343-68.PMID: 8823900 [PubMed - indexed for MEDLINE]Related articles

Hippocampal cell distributions in temporal lobe epilepsy: a comparison between patients with and without an early risk factor.

O'Connor WM, Masukawa L, Freese A, Sperling MR, French JA, O'Connor MJ.

Epilepsia. 1996 May;37(5):440-9.PMID: 8617172 [PubMed - indexed for MEDLINE]Related articles

Determination of HLA-B7 T-cell epitopes.

Freese A, Zavazava N.

Transpl Int. 1996;9 Suppl 1:S352-5.PMID: 8959863 [PubMed - indexed for MEDLINE]Related articles

Rat MHC class I peptides are immunogenic.

Zavazava N, Fandrich F, Ott KA, Freese A, Turnewitsch K.

Transpl Int. 1996;9 Suppl 1:S337-9.PMID: 8959859 [PubMed - indexed for MEDLINE]Related articles

Recognition of HLA-derived peptides in transplant patients.

Zavazava N, Stegmann S, Freese A, Müller-Ruchholtz W.

Transplant Proc. 1995 Feb;27(1):489-90. No abstract available. PMID: 7879072 [PubMed - indexed for MEDLINE]Related articles

An HSV-1 vector expressing tyrosine hydroxylase causes production and release of L-dopa from cultured rat striatal cells.

Geller AI, During MJ, Oh YJ, Freese A, O'Malley K.

J Neurochem. 1995 Feb;64(2):487-96.PMID: 7830040 [PubMed - indexed for MEDLINE]Related articlesFree article

The application of 5-bromodeoxyuridine in the management of CNS tumors.

Freese A, O'Rourke D, Judy K, O'Connor MJ.

J Neurooncol. 1994;20(1):81-95. Review.PMID: 7807187 [PubMed - indexed for MEDLINE]Related articles

Superficial siderosis of the central nervous system: magnetic resonance imaging and pathological correlation. Case report.

Janss AJ, Galetta SL, Freese A, Raps EC, Curtis MT, Grossman RI, Gomori JM, Duhaime AC.

J Neurosurg. 1993 Nov;79(5):756-60.PMID: 8410256 [PubMed - indexed for MEDLINE]Related articles

Long-term increases in neurotransmitter release from neuronal cells expressing a constitutively active adenylate cyclase from a herpes simplex virus type 1 vector.

Geller AI, During MJ, Haycock JW, Freese A, Neve R.

Proc Natl Acad Sci U S A. 1993 Aug 15;90(16):7603-7.PMID: 8102799 [PubMed - indexed for MEDLINE]Related articlesFree article

Basic fibroblast growth factor protects striatal neurons in vitro from NMDA-receptor mediated excitotoxicity.

Freese A, Finklestein SP, DiFiglia M.

Brain Res. 1992 Mar 20;575(2):351-5.PMID: 1349256 [PubMed - indexed for MEDLINE]Related articles

Biochemical and behavioral recovery in a rodent model of Parkinson's disease following stereotactic implantation of dopamine-containing liposomes.

During MJ, Freese A, Deutch AY, Kibat PG, Sabel BA, Langer R, Roth RH.

Exp Neurol. 1992 Feb;115(2):193-9.PMID: 1735466 [PubMed - indexed for MEDLINE]Related articles

Infection of cultured striatal neurons with a defective HSV-1 vector: implications for gene therapy.

Freese A, Geller A.

Nucleic Acids Res. 1991 Dec;19(25):7219-23.PMID: 1662813 [PubMed - indexed for MEDLINE]Related articlesFree article

Indolic and kynurenine pathway metabolites of tryptophan in rat brain: effect of precursor availability on in vivo release.

During MJ, Heyes MP, Freese A, Swartz KJ, Matson WR, Markey SP, Martin JB, Roth RH.

Adv Exp Med Biol. 1991;294:535-9. No abstract available. PMID: 1837690 [PubMed - indexed for MEDLINE]Related articles

HSV-1 vector mediated neuronal gene delivery. Strategies for molecular neuroscience and neurology.

Freese A, Geller AI, Neve R.

Biochem Pharmacol. 1990 Nov 15;40(10):2189-99. No abstract available. PMID: 2173924 [PubMed - indexed for MEDLINE]Related articles

Extended levodopa release from a subcutaneously implanted polymer matrix in rats.

Sabel BA, Dominiak P, Hüaser W, During MJ, Freese A.

Ann Neurol. 1990 Nov;28(5):714-7.PMID: 2260860 [PubMed - indexed for MEDLINE]Related articles

Levodopa delivery from controlled-release polymer matrix: delivery of more than 600 days in vitro and 225 days of elevated plasma levels after subcutaneous implantation in rats.

Sabel BA, Dominiak P, Häuser W, During MJ, Freese A.

J Pharmacol Exp Ther. 1990 Nov;255(2):914-22.PMID: 2243358 [PubMed - indexed for MEDLINE]Related articles

Cerebral synthesis and release of kynurenic acid: an endogenous antagonist of excitatory amino acid receptors.

Swartz KJ, During MJ, Freese A, Beal MF.

J Neurosci. 1990 Sep;10(9):2965-73.PMID: 2168940 [PubMed - indexed for MEDLINE]Related articlesFree article

The correlation between excitatory amino acid-induced current responses and excitotoxicity in striatal cultures.

Koroshetz WJ, Freese A, DiFiglia M.

Brain Res. 1990 Jun 25;521(1-2):265-72.PMID: 1976414 [PubMed - indexed for MEDLINE]Related articles

Characterization and mechanism of glutamate neurotoxicity in primary striatal cultures.

Freese A, DiFiglia M, Koroshetz WJ, Beal MF, Martin JB.

Brain Res. 1990 Jun 25;521(1-2):254-64.PMID: 1976413 [PubMed - indexed for MEDLINE]Related articles

Kynurenine metabolites of tryptophan: implications for neurologic diseases.

Freese A, Swartz KJ, During MJ, Martin JB.

Neurology. 1990 Apr;40(4):691-5. Review.PMID: 2181342 [PubMed - indexed for MEDLINE]Related articles