Epigenomic Profiles of African-American Transthyretin Val122Ile Carriers Reveals Putatively Dysregulated Amyloid Mechanisms.
Pathak GA, Wendt FR, De Lillo A, Nunez YZ, Goswami A, De Angelis F, Fuciarelli M, Kranzler HR, Gelernter J, Polimanti R.
Pathak GA, et al.
Circ Genom Precis Med. 2021 Feb;14(1):e003011. doi: 10.1161/CIRCGEN.120.003011. Epub 2021 Jan 11.
Circ Genom Precis Med. 2021.
PMID: 33428857
Free PMC article.
For OS, we observe 4 sites-2 sites in UBE2E3 and SEC14L5, and other 2 in intergenic regions (P1.810(-7)) and 3 regions overlapping SH3D21, EVA1B, LTB4R2, and CIDEB (P3.910(-7)). Functional protein-interaction module analysis identified ABCA1 (P=0.001) for heart disease. .. …
For OS, we observe 4 sites-2 sites in UBE2E3 and SEC14L5, and other 2 in intergenic regions (P1.810(-7)) and 3 regions overlapping SH3D21, …