PubMed

The role of genetic variation in peroxisome proliferator-activated receptors in the polycystic ovary syndrome (PCOS): an original case-control study followed by systematic review and meta-analysis of existing evidence.

San-Millán JL, Escobar-Morreale HF.

Clin Endocrinol (Oxf). 2009 Aug 4. [Epub ahead of print]PMID: 19681917 [PubMed - as supplied by publisher]Related articles

Role of haptoglobin in polycystic ovary syndrome (PCOS), obesity and disorders of glucose tolerance in premenopausal women.

Alvarez-Blasco F, Martínez-García MA, Luque-Ramírez M, Parraza N, San Millán JL, Escobar-Morreale HF.

PLoS One. 2009;4(5):e5606. Epub 2009 May 19.PMID: 19440331 [PubMed - indexed for MEDLINE]Related articlesFree article

Body iron stores and glucose intolerance in premenopausal women: role of hyperandrogenism, insulin resistance, and genomic variants related to inflammation, oxidative stress, and iron metabolism.

Martínez-García MA, Luque-Ramírez M, San-Millán JL, Escobar-Morreale HF.

Diabetes Care. 2009 Aug;32(8):1525-30. Epub 2009 Apr 28.PMID: 19401444 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of an antiandrogenic oral contraceptive pill compared with metformin on blood coagulation tests and endothelial function in women with the polycystic ovary syndrome: influence of obesity and smoking.

Luque-Ramírez M, Mendieta-Azcona C, del Rey Sánchez JM, Matíes M, Escobar-Morreale HF.

Eur J Endocrinol. 2009 Mar;160(3):469-80. Epub 2009 Jan 12.PMID: 19139031 [PubMed - indexed for MEDLINE]Related articles

Serum visceral adipose tissue-derived serine protease inhibitor concentrations in human obesity and polycystic ovary syndrome.

Escobar-Morreale HF, Luque-Ramírez M, San-Millán JL.

Diabetes Care. 2009 Jan;32(1):e6. No abstract available. PMID: 19114623 [PubMed - in process]Related articlesFree article

Polycystic ovary syndrome: treatment strategies and management.

Escobar-Morreale HF.

Expert Opin Pharmacother. 2008 Dec;9(17):2995-3008. Review.PMID: 19013863 [PubMed - indexed for MEDLINE]Related articles

Antiandrogenic contraceptives increase serum adiponectin in obese polycystic ovary syndrome patients.

Luque-Ramírez M, Alvarez-Blasco F, Escobar-Morreale HF.

Obesity (Silver Spring). 2009 Jan;17(1):3-9. Epub 2008 Nov 6.PMID: 18997670 [PubMed - indexed for MEDLINE]Related articles

The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report.

Azziz R, Carmina E, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale HF, Futterweit W, Janssen OE, Legro RS, Norman RJ, Taylor AE, Witchel SF; Task Force on the Phenotype of the Polycystic Ovary Syndrome of The Androgen Excess and PCOS Society.

Fertil Steril. 2009 Feb;91(2):456-88. Epub 2008 Oct 23. Review.PMID: 18950759 [PubMed - indexed for MEDLINE]Related articles

Retinol and alpha-Tocopherol in Morbid Obesity and Nonalcoholic Fatty Liver Disease.

Botella-Carretero JI, Balsa JA, Vázquez C, Peromingo R, Díaz-Enriquez M, Escobar-Morreale HF.

Obes Surg. 2008 Oct 2. [Epub ahead of print]PMID: 18830789 [PubMed - as supplied by publisher]Related articles

Serum osteoprotegerin concentrations are decreased in women with the polycystic ovary syndrome.

Escobar-Morreale HF, Botella-Carretero JI, Martínez-García MA, Luque-Ramírez M, Alvarez-Blasco F, San Millán JL.

Eur J Endocrinol. 2008 Sep;159(3):225-32. Epub 2008 Jun 25.PMID: 18579554 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of metformin versus ethinyl-estradiol plus cyproterone acetate on ambulatory blood pressure monitoring and carotid intima media thickness in women with the polycystic ovary syndrome.

Luque-Ramírez M, Mendieta-Azcona C, Alvarez-Blasco F, Escobar-Morreale HF.

Fertil Steril. 2009 Jun;91(6):2527-36. Epub 2008 Jun 18.PMID: 18565522 [PubMed - indexed for MEDLINE]Related articles

Serum uric acid concentration as non-classic cardiovascular risk factor in women with polycystic ovary syndrome: effect of treatment with ethinyl-estradiol plus cyproterone acetate versus metformin.

Luque-Ramírez M, Alvarez-Blasco F, Uriol Rivera MG, Escobar-Morreale HF.

Hum Reprod. 2008 Jul;23(7):1594-601. Epub 2008 Mar 27.PMID: 18375410 [PubMed - indexed for MEDLINE]Related articlesFree article

The increase in serum visfatin after bariatric surgery in morbidly obese women is modulated by weight loss, waist circumference, and presence or absence of diabetes before surgery.

Botella-Carretero JI, Luque-Ramírez M, Alvarez-Blasco F, Peromingo R, San Millán JL, Escobar-Morreale HF.

Obes Surg. 2008 Aug;18(8):1000-6. Epub 2008 Mar 19.PMID: 18350343 [PubMed - indexed for MEDLINE]Related articles

Hyperandrogenism, insulin resistance and hyperinsulinemia as cardiovascular risk factors in diabetes mellitus.

García-Romero G, Escobar-Morreale HF.

Curr Diabetes Rev. 2006 Feb;2(1):39-49. Review.PMID: 18220616 [PubMed - indexed for MEDLINE]Related articles

Proteomic analysis of human omental adipose tissue in the polycystic ovary syndrome using two-dimensional difference gel electrophoresis and mass spectrometry.

Cortón M, Botella-Carretero JI, López JA, Camafeita E, San Millán JL, Escobar-Morreale HF, Peral B.

Hum Reprod. 2008 Mar;23(3):651-61. Epub 2007 Dec 22.PMID: 18156650 [PubMed - indexed for MEDLINE]Related articlesFree article

The decrease in serum IL-18 levels after bariatric surgery in morbidly obese women is a time-dependent event.

Botella-Carretero JI, Alvarez-Blasco F, Martinez-García MA, Luque-Ramírez M, San Millán JL, Escobar-Morreale HF.

Obes Surg. 2007 Sep;17(9):1199-208.PMID: 18074495 [PubMed - indexed for MEDLINE]Related articles

A prospective study of the prevalence of nonclassical congenital adrenal hyperplasia among women presenting with hyperandrogenic symptoms and signs.

Escobar-Morreale HF, Sanchón R, San Millán JL.

J Clin Endocrinol Metab. 2008 Feb;93(2):527-33. Epub 2007 Nov 13.PMID: 18000084 [PubMed - indexed for MEDLINE]Related articlesFree article

Androgen excess is associated with the increased carotid intima-media thickness observed in young women with polycystic ovary syndrome.

Luque-Ramírez M, Mendieta-Azcona C, Alvarez-Blasco F, Escobar-Morreale HF.

Hum Reprod. 2007 Dec;22(12):3197-203. Epub 2007 Oct 11.PMID: 17933750 [PubMed - indexed for MEDLINE]Related articlesFree article

Obesity and the polycystic ovary syndrome.

Martínez-Bermejo E, Luque-Ramírez M, Escobar-Morreale HF.

Minerva Endocrinol. 2007 Sep;32(3):129-40. Review.PMID: 17912153 [PubMed - indexed for MEDLINE]Related articles

Abdominal adiposity and the polycystic ovary syndrome.

Escobar-Morreale HF, San Millán JL.

Trends Endocrinol Metab. 2007 Sep;18(7):266-72. Epub 2007 Aug 10. Review.PMID: 17693095 [PubMed - indexed for MEDLINE]Related articles

Vitamin D deficiency is associated with the metabolic syndrome in morbid obesity.

Botella-Carretero JI, Alvarez-Blasco F, Villafruela JJ, Balsa JA, Vázquez C, Escobar-Morreale HF.

Clin Nutr. 2007 Oct;26(5):573-80. Epub 2007 Jul 10.PMID: 17624643 [PubMed - indexed for MEDLINE]Related articles

Increased body iron stores of obese women with polycystic ovary syndrome are a consequence of insulin resistance and hyperinsulinism and are not a result of reduced menstrual losses.

Luque-Ramírez M, Alvarez-Blasco F, Botella-Carretero JI, Sanchón R, San Millán JL, Escobar-Morreale HF.

Diabetes Care. 2007 Sep;30(9):2309-13. Epub 2007 May 29.PMID: 17536071 [PubMed - indexed for MEDLINE]Related articlesFree article

Thyroid hormone deficiency and postmenopausal status independently increase serum osteoprotegerin concentrations in women.

Botella-Carretero JI, Alvarez-Blasco F, San Millán JL, Escobar-Morreale HF.

Eur J Endocrinol. 2007 May;156(5):539-45.PMID: 17468189 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of ethinyl-estradiol plus cyproterone acetate versus metformin effects on classic metabolic cardiovascular risk factors in women with the polycystic ovary syndrome.

Luque-Ramírez M, Alvarez-Blasco F, Botella-Carretero JI, Martínez-Bermejo E, Lasunción MA, Escobar-Morreale HF.

J Clin Endocrinol Metab. 2007 Jul;92(7):2453-61. Epub 2007 Apr 10.PMID: 17426085 [PubMed - indexed for MEDLINE]Related articlesFree article

Obesity is the major determinant of the abnormalities in blood pressure found in young women with the polycystic ovary syndrome.

Luque-Ramírez M, Alvarez-Blasco F, Mendieta-Azcona C, Botella-Carretero JI, Escobar-Morreale HF.

J Clin Endocrinol Metab. 2007 Jun;92(6):2141-8. Epub 2007 Mar 27.PMID: 17389696 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical review: Hyperandrogenism and polycystic ovary syndrome in women with type 1 diabetes mellitus.

Codner E, Escobar-Morreale HF.

J Clin Endocrinol Metab. 2007 Apr;92(4):1209-16. Epub 2007 Feb 6. Review.PMID: 17284617 [PubMed - indexed for MEDLINE]Related articlesFree article

Mutations in the hereditary hemochromatosis gene are not associated with the increased body iron stores observed in overweight and obese women with polycystic ovary syndrome.

Botella-Carretero JI, Luque-Ramírez M, Alvarez-Blasco F, San Millán JL, Escobar-Morreale HF.

Diabetes Care. 2006 Nov;29(11):2556. No abstract available. PMID: 17065702 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential gene expression profile in omental adipose tissue in women with polycystic ovary syndrome.

Cortón M, Botella-Carretero JI, Benguría A, Villuendas G, Zaballos A, San Millán JL, Escobar-Morreale HF, Peral B.

J Clin Endocrinol Metab. 2007 Jan;92(1):328-37. Epub 2006 Oct 24.PMID: 17062763 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevalence and characteristics of the polycystic ovary syndrome in overweight and obese women.

Alvarez-Blasco F, Botella-Carretero JI, San Millán JL, Escobar-Morreale HF.

Arch Intern Med. 2006 Oct 23;166(19):2081-6.PMID: 17060537 [PubMed - indexed for MEDLINE]Related articlesFree article

Positions statement: criteria for defining polycystic ovary syndrome as a predominantly hyperandrogenic syndrome: an Androgen Excess Society guideline.

Azziz R, Carmina E, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale HF, Futterweit W, Janssen OE, Legro RS, Norman RJ, Taylor AE, Witchel SF; Androgen Excess Society.

J Clin Endocrinol Metab. 2006 Nov;91(11):4237-45. Epub 2006 Aug 29.PMID: 16940456 [PubMed - indexed for MEDLINE]Related articlesFree article

The PON1-108C/T polymorphism, and not the polycystic ovary syndrome, is an important determinant of reduced serum paraoxonase activity in premenopausal women.

San Millán JL, Alvarez-Blasco F, Luque-Ramírez M, Botella-Carretero JI, Escobar-Morreale HF.

Hum Reprod. 2006 Dec;21(12):3157-61. Epub 2006 Jul 31.PMID: 16880229 [PubMed - indexed for MEDLINE]Related articlesFree article

The ACAA-insertion/deletion polymorphism at the 3' UTR of the IGF-II receptor gene is associated with type 2 diabetes and surrogate markers of insulin resistance.

Villuendas G, Botella-Carretero JI, López-Bermejo A, Gubern C, Ricart W, Fernández-Real JM, San Millán JL, Escobar-Morreale HF.

Eur J Endocrinol. 2006 Aug;155(2):331-6.PMID: 16868148 [PubMed - indexed for MEDLINE]Related articlesFree article

Reproductive outcome of women with 21-hydroxylase-deficient nonclassic adrenal hyperplasia.

Moran C, Azziz R, Weintrob N, Witchel SF, Rohmer V, Dewailly D, Marcondes JA, Pugeat M, Speiser PW, Pignatelli D, Mendonca BB, Bachega TA, Escobar-Morreale HF, Carmina E, Fruzzetti F, Kelestimur F.

J Clin Endocrinol Metab. 2006 Sep;91(9):3451-6. Epub 2006 Jul 5.PMID: 16822826 [PubMed - indexed for MEDLINE]Related articlesFree article

Adiponectin and resistin in PCOS: a clinical, biochemical and molecular genetic study.

Escobar-Morreale HF, Villuendas G, Botella-Carretero JI, Alvarez-Blasco F, Sanchón R, Luque-Ramírez M, San Millán JL.

Hum Reprod. 2006 Sep;21(9):2257-65. Epub 2006 May 4.PMID: 16675483 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of thyroid hormones on serum levels of adipokines as studied in patients with differentiated thyroid carcinoma during thyroxine withdrawal.

Botella-Carretero JI, Alvarez-Blasco F, Sancho J, Escobar-Morreale HF.

Thyroid. 2006 Apr;16(4):397-402.PMID: 16646687 [PubMed - indexed for MEDLINE]Related articles

Mechanisms of adaptation to iodine deficiency in rats: thyroid status is tissue specific. Its relevance for man.

Pedraza PE, Obregon MJ, Escobar-Morreale HF, del Rey FE, de Escobar GM.

Endocrinology. 2006 May;147(5):2098-108. Epub 2006 Feb 2.PMID: 16455775 [PubMed - indexed for MEDLINE]Related articlesFree article

Genomic variants in polycystic ovary syndrome.

Luque-Ramírez M, San Millán JL, Escobar-Morreale HF.

Clin Chim Acta. 2006 Apr;366(1-2):14-26. Epub 2005 Dec 7. Review.PMID: 16337616 [PubMed - indexed for MEDLINE]Related articles

The polycystic ovary syndrome associated with morbid obesity may resolve after weight loss induced by bariatric surgery.

Escobar-Morreale HF, Botella-Carretero JI, Alvarez-Blasco F, Sancho J, San Millán JL.

J Clin Endocrinol Metab. 2005 Dec;90(12):6364-9. Epub 2005 Sep 27.PMID: 16189250 [PubMed - indexed for MEDLINE]Related articlesFree article

The effects of thyroid hormones on circulating markers of cell-mediated immune response, as studied in patients with differentiated thyroid carcinoma before and during thyroxine withdrawal.

Botella-Carretero JI, Prados A, Manzano L, Montero MT, Escribano L, Sancho J, Escobar-Morreale HF.

Eur J Endocrinol. 2005 Aug;153(2):223-30.PMID: 16061828 [PubMed - indexed for MEDLINE]Related articlesFree article

Body iron stores are increased in overweight and obese women with polycystic ovary syndrome.

Escobar-Morreale HF, Luque-Ramírez M, Alvarez-Blasco F, Botella-Carretero JI, Sancho J, San Millán JL.

Diabetes Care. 2005 Aug;28(8):2042-4. No abstract available. PMID: 16043756 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphisms in the insulin receptor substrate-1 (IRS-1) gene and the insulin receptor substrate-2 (IRS-2) gene influence glucose homeostasis and body mass index in women with polycystic ovary syndrome and non-hyperandrogenic controls.

Villuendas G, Botella-Carretero JI, Roldán B, Sancho J, Escobar-Morreale HF, San Millán JL.

Hum Reprod. 2005 Nov;20(11):3184-91. Epub 2005 Jul 21.PMID: 16037106 [PubMed - indexed for MEDLINE]Related articlesFree article

REVIEW: Treatment of hypothyroidism with combinations of levothyroxine plus liothyronine.

Escobar-Morreale HF, Botella-Carretero JI, Escobar del Rey F, Morreale de Escobar G.

J Clin Endocrinol Metab. 2005 Aug;90(8):4946-54. Epub 2005 May 31. Review.PMID: 15928247 [PubMed - indexed for MEDLINE]Related articlesFree article

A study of the hexose-6-phosphate dehydrogenase gene R453Q and 11beta-hydroxysteroid dehydrogenase type 1 gene 83557insA polymorphisms in the polycystic ovary syndrome.

San Millán JL, Botella-Carretero JI, Alvarez-Blasco F, Luque-Ramírez M, Sancho J, Moghetti P, Escobar-Morreale HF.

J Clin Endocrinol Metab. 2005 Jul;90(7):4157-62. Epub 2005 Apr 12.PMID: 15827106 [PubMed - indexed for MEDLINE]Related articlesFree article

Thyroid hormone replacement therapy in primary hypothyroidism: a randomized trial comparing L-thyroxine plus liothyronine with L-thyroxine alone.

Escobar-Morreale HF, Botella-Carretero JI, Gómez-Bueno M, Galán JM, Barrios V, Sancho J.

Ann Intern Med. 2005 Mar 15;142(6):412-24.PMID: 15767619 [PubMed - indexed for MEDLINE]Related articlesFree article

Macroprolactinemia in women presenting with hyperandrogenic symptoms: Implications for the management of polycystic ovary syndrome.

Escobar-Morreale HF.

Fertil Steril. 2004 Dec;82(6):1697-9.PMID: 15589886 [PubMed - indexed for MEDLINE]Related articles

The molecular-genetic basis of functional hyperandrogenism and the polycystic ovary syndrome.

Escobar-Morreale HF, Luque-Ramírez M, San Millán JL.

Endocr Rev. 2005 Apr;26(2):251-82. Epub 2004 Nov 23. Review.PMID: 15561799 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of the polycystic ovary syndrome with genomic variants related to insulin resistance, type 2 diabetes mellitus, and obesity.

San Millán JL, Cortón M, Villuendas G, Sancho J, Peral B, Escobar-Morreale HF.

J Clin Endocrinol Metab. 2004 Jun;89(6):2640-6.PMID: 15181035 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic thyrotropin-suppressive therapy with levothyroxine and short-term overt hypothyroidism after thyroxine withdrawal are associated with undesirable cardiovascular effects in patients with differentiated thyroid carcinoma.

Botella-Carretero JI, Gómez-Bueno M, Barrios V, Caballero C, García-Robles R, Sancho J, Escobar-Morreale HF.

Endocr Relat Cancer. 2004 Jun;11(2):345-56.PMID: 15163309 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic basis of metabolic abnormalities in polycystic ovary syndrome: implications for therapy.

Roldán B, San Millán JL, Escobar-Morreale HF.

Am J Pharmacogenomics. 2004;4(2):93-107. Review.PMID: 15059032 [PubMed - indexed for MEDLINE]Related articles

Weight gain and cardiovascular risk factors during smoking cessation with bupropion or nicotine.

Botella-Carretero JI, Escobar-Morreale HF, Martín I, Valero AM, Alvarez F, García G, Varela C, Cantarero M.

Horm Metab Res. 2004 Mar;36(3):178-82.PMID: 15057672 [PubMed - indexed for MEDLINE]Related articles