PubMed

Sequence feature variant type (sfvt) analysis of the hla genetic association in juvenile idiopathic arthritis.

Thomson G, Marthandan N, Hollenbach JA, Mack SJ, Erlich HA, Single RM, Waller MJ, Marsh SG, Guidry PA, Karp DR, Scheuermann RH, Thompson SD, Glass DN, Helmberg W.

Pac Symp Biocomput. 2010:359-70.PMID: 19908388 [PubMed - in process]Related articlesFree article

High-resolution, high-throughput HLA genotyping by next-generation sequencing.

Bentley G, Higuchi R, Hoglund B, Goodridge D, Sayer D, Trachtenberg EA, Erlich HA.

Tissue Antigens. 2009 Nov;74(5):393-403.PMID: 19845894 [PubMed - in process]Related articles

Susceptibility to Crohn's disease is mediated by KIR2DL2/KIR2DL3 heterozygosity and the HLA-C ligand.

Hollenbach JA, Ladner MB, Saeteurn K, Taylor KD, Mei L, Haritunians T, McGovern DP, Erlich HA, Rotter JI, Trachtenberg EA.

Immunogenetics. 2009 Sep 30. [Epub ahead of print]PMID: 19789864 [PubMed - as supplied by publisher]Related articles

Reevaluation of the interaction between HLA-DRB1 shared epitope alleles, PTPN22, and smoking in determining susceptibility to autoantibody-positive and autoantibody-negative rheumatoid arthritis in a large UK Caucasian population.

Morgan AW, Thomson W, Martin SG; Yorkshire Early Arthritis Register Consortium, Carter AM; UK Rheumatoid Arthritis Genetics Consortium, Erlich HA, Barton A, Hocking L, Reid DM, Harrison P, Wordsworth P, Steer S, Worthington J, Emery P, Wilson AG, Barrett JH.

Arthritis Rheum. 2009 Sep;60(9):2565-76.PMID: 19714585 [PubMed - indexed for MEDLINE]Related articles

The identification of a new HLA-DPB1 allele (*1302) in one family and the detection of a recombination event between the DR and the DQ regions in another Caucasian T1DGC family.

Moonsamy P, Bonella P, Goodwin G, Dolan L, Erlich HA; T1DGC.

Tissue Antigens. 2009 Sep;74(3):268-70.PMID: 19691641 [PubMed - in process]Related articles

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.

Barrett JC, Clayton DG, Concannon P, Akolkar B, Cooper JD, Erlich HA, Julier C, Morahan G, Nerup J, Nierras C, Plagnol V, Pociot F, Schuilenburg H, Smyth DJ, Stevens H, Todd JA, Walker NM, Rich SS; The Type 1 Diabetes Genetics Consortium.

Nat Genet. 2009 May 10. [Epub ahead of print]PMID: 19430480 [PubMed - as supplied by publisher]Related articles

Defining multiple common "completely" conserved major histocompatibility complex SNP haplotypes.

Baschal EE, Aly TA, Jasinski JM, Steck AK, Noble JA, Erlich HA, Eisenbarth GS; Type 1 Diabetes Genetics Consortium.

Clin Immunol. 2009 Aug;132(2):203-14. Epub 2009 May 7.PMID: 19427271 [PubMed - indexed for MEDLINE]Related articles

Do non-HLA genes influence development of persistent islet autoimmunity and type 1 diabetes in children with high-risk HLA-DR,DQ genotypes?

Steck AK, Zhang W, Bugawan TL, Barriga KJ, Blair A, Erlich HA, Eisenbarth GS, Norris JM, Rewers MJ.

Diabetes. 2009 Apr;58(4):1028-33. Epub 2009 Feb 2.PMID: 19188433 [PubMed - indexed for MEDLINE]Related articlesFree article

The frequent and conserved DR3-B8-A1 extended haplotype confers less diabetes risk than other DR3 haplotypes.

Baschal EE, Aly TA, Jasinski JM, Steck AK, Johnson KN, Noble JA, Erlich HA, Eisenbarth GS; Type 1 Diabetes Genetics Consortium.

Diabetes Obes Metab. 2009 Feb;11 Suppl 1:25-30.PMID: 19143812 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide scan for linkage to type 1 diabetes in 2,496 multiplex families from the Type 1 Diabetes Genetics Consortium.

Concannon P, Chen WM, Julier C, Morahan G, Akolkar B, Erlich HA, Hilner JE, Nerup J, Nierras C, Pociot F, Todd JA, Rich SS; Type 1 Diabetes Genetics Consortium.

Diabetes. 2009 Apr;58(4):1018-22. Epub 2009 Jan 9.PMID: 19136655 [PubMed - indexed for MEDLINE]Related articlesFree article

A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients.

Wang X, Cheng S, Brophy VH, Erlich HA, Mannhalter C, Berger K, Lalouschek W, Browner WS, Shi Y, Ringelstein EB, Kessler C, Luedemann J, Lindpaintner K, Liu L, Ridker PM, Zee RY, Cook NR; RMS Stroke SNP Consortium.

Stroke. 2009 Mar;40(3):683-95. Epub 2009 Jan 8. Review.PMID: 19131662 [PubMed - indexed for MEDLINE]Related articles

Genetic variation in candidate osteoporosis genes, bone mineral density, and fracture risk: the study of osteoporotic fractures.

Tranah GJ, Taylor BC, Lui LY, Zmuda JM, Cauley JA, Ensrud KE, Hillier TA, Hochberg MC, Li J, Rhees BK, Erlich HA, Sternlicht MD, Peltz G, Cummings SR; Study of Osteoporotic Fractures (SOF) Research Group.

Calcif Tissue Int. 2008 Sep;83(3):155-66. Epub 2008 Sep 12.PMID: 18787887 [PubMed - indexed for MEDLINE]Related articlesFree article

MHC loci affecting cervical cancer risk: distinguishing the effects of HLA-DQB1 and non-HLA genes TNF, LTA, TAP1 and TAP2.

Ivansson EL, Magnusson JJ, Magnusson PK, Erlich HA, Gyllensten UB.

Genes Immun. 2008 Oct;9(7):613-23. Epub 2008 Jul 24.PMID: 18650831 [PubMed - indexed for MEDLINE]Related articles

A human type 1 diabetes susceptibility locus maps to chromosome 21q22.3.

Concannon P, Onengut-Gumuscu S, Todd JA, Smyth DJ, Pociot F, Bergholdt R, Akolkar B, Erlich HA, Hilner JE, Julier C, Morahan G, Nerup J, Nierras CR, Chen WM, Rich SS; Type 1 Diabetes Genetics Consortium.

Diabetes. 2008 Oct;57(10):2858-61. Epub 2008 Jul 22.PMID: 18647951 [PubMed - indexed for MEDLINE]Related articlesFree article

Type 1 diabetes risk for human leukocyte antigen (HLA)-DR3 haplotypes depends on genotypic context: association of DPB1 and HLA class I loci among DR3- and DR4-matched Italian patients and controls.

Noble JA, Martin A, Valdes AM, Lane JA, Galgani A, Petrone A, Lorini R, Pozzilli P, Buzzetti R, Erlich HA.

Hum Immunol. 2008 Apr-May;69(4-5):291-300. Epub 2008 Mar 26.PMID: 18486765 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of single nucleotide polymorphisms identifies major type 1A diabetes locus telomeric of the major histocompatibility complex.

Aly TA, Baschal EE, Jahromi MM, Fernando MS, Babu SR, Fingerlin TE, Kretowski A, Erlich HA, Fain PR, Rewers MJ, Eisenbarth GS.

Diabetes. 2008 Mar;57(3):770-6. Epub 2007 Dec 7.PMID: 18065518 [PubMed - indexed for MEDLINE]Related articlesFree article

Alteration of cellular and humoral immunity by mutant p53 protein and processed mutant peptide in head and neck cancer.

Couch ME, Ferris RL, Brennan JA, Koch WM, Jaffee EM, Leibowitz MS, Nepom GT, Erlich HA, Sidransky D.

Clin Cancer Res. 2007 Dec 1;13(23):7199-206.PMID: 18056201 [PubMed - indexed for MEDLINE]Related articlesFree article

Intercellular adhesion molecule 1 (ICAM1) Lys56Met and Gly241Arg gene variants, plasma-soluble ICAM1 concentrations, and risk of incident cardiovascular events in 23,014 initially healthy white women.

Zee RY, Cheng S, Erlich HA, Lindpaintner K, Rifai N, Buring JE, Ridker PM.

Stroke. 2007 Dec;38(12):3152-7. Epub 2007 Oct 25.PMID: 17962597 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential effects of DRB1*0301 and DQA1*0501-DQB1*0201 on the activation and progression of islet cell autoimmunity.

Eller E, Vardi P, McFann KK, Babu SR, Yu L, Bugawan TL, Erlich HA, Eisenbarth GS, Fain PR.

Genes Immun. 2007 Dec;8(8):628-33. Epub 2007 Aug 30.PMID: 17728790 [PubMed - indexed for MEDLINE]Related articles

Variants of chemokine receptor 2 and interleukin 4 receptor, but not interleukin 10 or Fas ligand, increase risk of cervical cancer.

Ivansson EL, Gustavsson IM, Magnusson JJ, Steiner LL, Magnusson PK, Erlich HA, Gyllensten UB.

Int J Cancer. 2007 Dec 1;121(11):2451-7.PMID: 17688234 [PubMed - indexed for MEDLINE]Related articles

Relative predispositional effects of HLA class II DRB1-DQB1 haplotypes and genotypes on type 1 diabetes: a meta-analysis.

Thomson G, Valdes AM, Noble JA, Kockum I, Grote MN, Najman J, Erlich HA, Cucca F, Pugliese A, Steenkiste A, Dorman JS, Caillat-Zucman S, Hermann R, Ilonen J, Lambert AP, Bingley PJ, Gillespie KM, Lernmark A, Sanjeevi CB, Rønningen KS, Undlien DE, Thorsby E, Petrone A, Buzzetti R, Koeleman BP, Roep BO, Saruhan-Direskeneli G, Uyar FA, Günoz H, Gorodezky C, Alaez C, Boehm BO, Mlynarski W, Ikegami H, Berrino M, Fasano ME, Dametto E, Israel S, Brautbar C, Santiago-Cortes A, Frazer de Llado T, She JX, Bugawan TL, Rotter JI, Raffel L, Zeidler A, Leyva-Cobian F, Hawkins BR, Chan SH, Castano L, Pociot F, Nerup J.

Tissue Antigens. 2007 Aug;70(2):110-27.PMID: 17610416 [PubMed - indexed for MEDLINE]Related articles

HLA-DPB1*0402 protects against type 1A diabetes autoimmunity in the highest risk DR3-DQB1*0201/DR4-DQB1*0302 DAISY population.

Baschal EE, Aly TA, Babu SR, Fernando MS, Yu L, Miao D, Barriga KJ, Norris JM, Noble JA, Erlich HA, Rewers MJ, Eisenbarth GS.

Diabetes. 2007 Sep;56(9):2405-9. Epub 2007 May 18.PMID: 17513705 [PubMed - indexed for MEDLINE]Related articlesFree article

Population samples and genotyping technology.

Mack SJ, Sanchez-Mazas A, Single RM, Meyer D, Hill J, Dron HA, Jani AJ, Thomson G, Erlich HA.

Tissue Antigens. 2007 Apr;69 Suppl 1:188-91. Review.PMID: 17445198 [PubMed - indexed for MEDLINE]Related articles

14th International HLA and Immunogenetics Workshop: report of progress in methodology, data collection, and analyses.

Single RM, Meyer D, Mack SJ, Lancaster A, Erlich HA, Thomson G.

Tissue Antigens. 2007 Apr;69 Suppl 1:185-7. Review.PMID: 17445197 [PubMed - indexed for MEDLINE]Related articles

Homocysteine, 5,10-methylenetetrahydrofolate reductase 677C>T polymorphism, nutrient intake, and incident cardiovascular disease in 24,968 initially healthy women.

Zee RY, Mora S, Cheng S, Erlich HA, Lindpaintner K, Rifai N, Buring JE, Ridker PM.

Clin Chem. 2007 May;53(5):845-51. Epub 2007 Mar 1.PMID: 17332146 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphisms of the renin-angiotensin system genes predict progression of subclinical coronary atherosclerosis.

Kretowski A, McFann K, Hokanson JE, Maahs D, Kinney G, Snell-Bergeon JK, Wadwa RP, Eckel RH, Ogden L, Garg S, Li J, Cheng S, Erlich HA, Rewers M.

Diabetes. 2007 Mar;56(3):863-71.PMID: 17327458 [PubMed - indexed for MEDLINE]Related articlesFree article

Linkage disequilibrium with predisposing DR3 haplotypes accounts for apparent effects of tumor necrosis factor and lymphotoxin-alpha polymorphisms on type 1 diabetes susceptibility.

Noble JA, Valdes AM, Lane JA, Green AE, Erlich HA.

Hum Immunol. 2006 Dec;67(12):999-1004. Epub 2006 Oct 30.PMID: 17174749 [PubMed - indexed for MEDLINE]Related articlesFree article

Celiac disease and HLA in a Bedouin kindred.

Eller E, Vardi P, Babu SR, Bugawan TL, Erlich HA, Yu L, Fain PR.

Hum Immunol. 2006 Nov;67(11):940-50. Epub 2006 Sep 18.PMID: 17145374 [PubMed - indexed for MEDLINE]Related articlesFree article

Normal but increasing hemoglobin A1c levels predict progression from islet autoimmunity to overt type 1 diabetes: Diabetes Autoimmunity Study in the Young (DAISY).

Stene LC, Barriga K, Hoffman M, Kean J, Klingensmith G, Norris JM, Erlich HA, Eisenbarth GS, Rewers M.

Pediatr Diabetes. 2006 Oct;7(5):247-53.PMID: 17054445 [PubMed - indexed for MEDLINE]Related articles

Rotavirus infection frequency and risk of celiac disease autoimmunity in early childhood: a longitudinal study.

Stene LC, Honeyman MC, Hoffenberg EJ, Haas JE, Sokol RJ, Emery L, Taki I, Norris JM, Erlich HA, Eisenbarth GS, Rewers M.

Am J Gastroenterol. 2006 Oct;101(10):2333-40.PMID: 17032199 [PubMed - indexed for MEDLINE]Related articles

Complex gene-gene interactions in multiple sclerosis: a multifactorial approach reveals associations with inflammatory genes.

Motsinger AA, Brassat D, Caillier SJ, Erlich HA, Walker K, Steiner LL, Barcellos LF, Pericak-Vance MA, Schmidt S, Gregory S, Hauser SL, Haines JL, Oksenberg JR, Ritchie MD.

Neurogenetics. 2007 Jan;8(1):11-20. Epub 2006 Sep 22.PMID: 17024427 [PubMed - indexed for MEDLINE]Related articles

Extreme genetic risk for type 1A diabetes.

Aly TA, Ide A, Jahromi MM, Barker JM, Fernando MS, Babu SR, Yu L, Miao D, Erlich HA, Fain PR, Barriga KJ, Norris JM, Rewers MJ, Eisenbarth GS.

Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):14074-9. Epub 2006 Sep 11.PMID: 16966600 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphisms of the phosphodiesterase 4D, cAMP-specific (PDE4D) gene and risk of ischemic stroke: a prospective, nested case-control evaluation.

Zee RY, Brophy VH, Cheng S, Hegener HH, Erlich HA, Ridker PM.

Stroke. 2006 Aug;37(8):2012-7. Epub 2006 Jul 6.PMID: 16825591 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic variants of arachidonate 5-lipoxygenase-activating protein, and risk of incident myocardial infarction and ischemic stroke: a nested case-control approach.

Zee RY, Cheng S, Hegener HH, Erlich HA, Ridker PM.

Stroke. 2006 Aug;37(8):2007-11. Epub 2006 Jun 15.PMID: 16778124 [PubMed - indexed for MEDLINE]Related articlesFree article

The apolipoprotein A-IV Gln360His polymorphism predicts progression of coronary artery calcification in patients with type 1 diabetes.

Kretowski A, Hokanson JE, McFann K, Kinney GL, Snell-Bergeon JK, Maahs DM, Wadwa RP, Eckel RH, Ogden LG, Garg SK, Li J, Cheng S, Erlich HA, Rewers M.

Diabetologia. 2006 Aug;49(8):1946-54. Epub 2006 Jun 13.PMID: 16770585 [PubMed - indexed for MEDLINE]Related articles

Signatures of demographic history and natural selection in the human major histocompatibility complex Loci.

Meyer D, Single RM, Mack SJ, Erlich HA, Thomson G.

Genetics. 2006 Aug;173(4):2121-42. Epub 2006 May 15.PMID: 16702436 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of phosphodiesterase 4D polymorphisms with ischemic stroke in a US population stratified by hypertension status.

Brophy VH, Ro SK, Rhees BK, Lui LY, Lee JM, Umblas N, Bentley LG, Li J, Cheng S, Browner WS, Erlich HA.

Stroke. 2006 Jun;37(6):1385-90. Epub 2006 May 4.PMID: 16675738 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphism in the beta2-adrenergic receptor and lipoprotein lipase genes as risk determinants for idiopathic venous thromboembolism: a multilocus, population-based, prospective genetic analysis.

Zee RY, Cook NR, Cheng S, Erlich HA, Lindpaintner K, Ridker PM.

Circulation. 2006 May 9;113(18):2193-200. Epub 2006 May 1.PMID: 16651467 [PubMed - indexed for MEDLINE]Related articlesFree article

Multi-SNP analysis of MHC region: remarkable conservation of HLA-A1-B8-DR3 haplotype.

Aly TA, Eller E, Ide A, Gowan K, Babu SR, Erlich HA, Rewers MJ, Eisenbarth GS, Fain PR.

Diabetes. 2006 May;55(5):1265-9.PMID: 16644681 [PubMed - indexed for MEDLINE]Related articlesFree article

Multifactor dimensionality reduction reveals gene-gene interactions associated with multiple sclerosis susceptibility in African Americans.

Brassat D, Motsinger AA, Caillier SJ, Erlich HA, Walker K, Steiner LL, Cree BA, Barcellos LF, Pericak-Vance MA, Schmidt S, Gregory S, Hauser SL, Haines JL, Oksenberg JR, Ritchie MD.

Genes Immun. 2006 Jun;7(4):310-5. Epub 2006 Apr 20.PMID: 16625214 [PubMed - indexed for MEDLINE]Related articles

Susceptibility to type 1 diabetes is associated with ApoCIII gene haplotypes.

Hokanson JE, Kinney GL, Cheng S, Erlich HA, Kretowski A, Rewers M.

Diabetes. 2006 Mar;55(3):834-8.PMID: 16505251 [PubMed - indexed for MEDLINE]Related articlesFree article

Multi-locus candidate gene polymorphisms and risk of myocardial infarction: a population-based, prospective genetic analysis.

Zee RY, Cook NR, Cheng S, Erlich HA, Lindpaintner K, Ridker PM.

J Thromb Haemost. 2006 Feb;4(2):341-8.PMID: 16420563 [PubMed - indexed for MEDLINE]Related articles

Genetic prediction of autoimmunity: initial oligogenic prediction of anti-islet autoimmunity amongst DR3/DR4-DQ8 relatives of patients with type 1A diabetes.

Aly TA, Ide A, Humphrey K, Barker JM, Steck A, Erlich HA, Yu L, Miao D, Redondo MJ, McFann K, Roberts CM, Babu SR, Norris JM, Eisenbarth GS, Rewers MJ.

J Autoimmun. 2005;25 Suppl:40-5. Epub 2005 Oct 19. Review.PMID: 16242305 [PubMed - indexed for MEDLINE]Related articles

Type 1 diabetes: evidence for susceptibility loci from four genome-wide linkage scans in 1,435 multiplex families.

Concannon P, Erlich HA, Julier C, Morahan G, Nerup J, Pociot F, Todd JA, Rich SS; Type 1 Diabetes Genetics Consortium.

Diabetes. 2005 Oct;54(10):2995-3001.PMID: 16186404 [PubMed - indexed for MEDLINE]Related articlesFree article

Homozygosity for premature stop codon of the MHC class I chain-related gene A (MIC-A) is associated with early activation of islet autoimmunity of DR3/4-DQ2/8 high risk DAISY relatives.

Ide A, Babu SR, Robles DT, Wang T, Erlich HA, Bugawan TL, Rewers M, Fain PR, Eisenbarth GS.

J Clin Immunol. 2005 Jul;25(4):303-8.PMID: 16133985 [PubMed - indexed for MEDLINE]Related articles

Newborn HLA-DR,DQ genotype screening: age- and ethnicity-specific type 1 diabetes risk estimates.

Emery LM, Babu S, Bugawan TL, Norris JM, Erlich HA, Eisenbarth GS, Rewers M.

Pediatr Diabetes. 2005 Sep;6(3):136-44.PMID: 16109069 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of non-HLA genes with type 1 diabetes autoimmunity.

Steck AK, Bugawan TL, Valdes AM, Emery LM, Blair A, Norris JM, Redondo MJ, Babu SR, Erlich HA, Eisenbarth GS, Rewers MJ.

Diabetes. 2005 Aug;54(8):2482-6.PMID: 16046318 [PubMed - indexed for MEDLINE]Related articlesFree article

Nomenclature for Factors of the HLA System, 2004.

Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Geraghty DE, Hansen JA, Hurley CK, Mach B, Mayr WR, Parham P, Petersdorf EW, Sasazuki T, Schreuder GM, Strominger JL, Svejgaard A, Terasaki PI, Trowsdale J.

Hum Immunol. 2005 May;66(5):571-636. Epub 2005 Mar 3. No abstract available. PMID: 15935895 [PubMed - indexed for MEDLINE]Related articles

"Extended" A1, B8, DR3 haplotype shows remarkable linkage disequilibrium but is similar to nonextended haplotypes in terms of diabetes risk.

Ide A, Babu SR, Robles DT, Wang T, Erlich HA, Bugawan TL, Rewers M, Fain PR, Eisenbarth GS.

Diabetes. 2005 Jun;54(6):1879-83.PMID: 15919812 [PubMed - indexed for MEDLINE]Related articlesFree article

Risk of celiac disease autoimmunity and timing of gluten introduction in the diet of infants at increased risk of disease.

Norris JM, Barriga K, Hoffenberg EJ, Taki I, Miao D, Haas JE, Emery LM, Sokol RJ, Erlich HA, Eisenbarth GS, Rewers M.

JAMA. 2005 May 18;293(19):2343-51.PMID: 15900004 [PubMed - indexed for MEDLINE]Related articlesFree article