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    Results: 34

    1.

    Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design?

    Heid IM, Huth C, Loos RJ, Kronenberg F, Adamkova V, Anand SS, Ardlie K, Biebermann H, Bjerregaard P, Boeing H, Bouchard C, Ciullo M, Cooper JA, Corella D, Dina C, Engert JC, Fisher E, Francès F, Froguel P, Hebebrand J, Hegele RA, Hinney A, Hoehe MR, Hu FB, Hubacek JA, Humphries SE, Hunt SC, Illig T, Järvelin MR, Kaakinen M, Kollerits B, Krude H, Kumar J, Lange LA, Langer B, Li S, Luchner A, Lyon HN, Meyre D, Mohlke KL, Mooser V, Nebel A, Nguyen TT, Paulweber B, Perusse L, Qi L, Rankinen T, Rosskopf D, Schreiber S, Sengupta S, Sorice R, Suk A, Thorleifsson G, Thorsteinsdottir U, Völzke H, Vimaleswaran KS, Wareham NJ, Waterworth D, Yusuf S, Lindgren C, McCarthy MI, Lange C, Hirschhorn JN, Laird N, Wichmann HE.

    PLoS Genet. 2009 Oct;5(10):e1000694. Epub 2009 Oct 23.PMID: 19851442 [PubMed - in process]Related articlesFree article

    2.

    Fine mapping and association studies of a high-density lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian subjects.

    Dastani Z, Pajukanta P, Marcil M, Rudzicz N, Ruel I, Bailey SD, Lee JC, Lemire M, Faith J, Platko J, Rioux J, Hudson TJ, Gaudet D, Engert JC, Genest J.

    Eur J Hum Genet. 2009 Oct 21. [Epub ahead of print]PMID: 19844255 [PubMed - as supplied by publisher]Related articles

    3.

    Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease.

    Elliott P, Chambers JC, Zhang W, Clarke R, Hopewell JC, Peden JF, Erdmann J, Braund P, Engert JC, Bennett D, Coin L, Ashby D, Tzoulaki I, Brown IJ, Mt-Isa S, McCarthy MI, Peltonen L, Freimer NB, Farrall M, Ruokonen A, Hamsten A, Lim N, Froguel P, Waterworth DM, Vollenweider P, Waeber G, Jarvelin MR, Mooser V, Scott J, Hall AS, Schunkert H, Anand SS, Collins R, Samani NJ, Watkins H, Kooner JS.

    JAMA. 2009 Jul 1;302(1):37-48.PMID: 19567438 [PubMed - indexed for MEDLINE]Related articles

    4.

    The functional variant rs1048990 in PSMA6 is associated with susceptibility to myocardial infarction in a Chinese population.

    Liu X, Wang X, Shen Y, Wu L, Ruan X, Lindpaintner K, Yusuf S, Engert JC, Anand S, Tan X, Liu L.

    Atherosclerosis. 2009 Sep;206(1):199-203. Epub 2009 Feb 12.PMID: 19272601 [PubMed - in process]Related articles

    5.

    Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.

    Myocardial Infarction Genetics Consortium, Kathiresan S, Voight BF, Purcell S, Musunuru K, Ardissino D, Mannucci PM, Anand S, Engert JC, Samani NJ, Schunkert H, Erdmann J, Reilly MP, Rader DJ, Morgan T, Spertus JA, Stoll M, Girelli D, McKeown PP, Patterson CC, Siscovick DS, O'Donnell CJ, Elosua R, Peltonen L, Salomaa V, Schwartz SM, Melander O, Altshuler D, Ardissino D, Merlini PA, Berzuini C, Bernardinelli L, Peyvandi F, Tubaro M, Celli P, Ferrario M, Fetiveau R, Marziliano N, Casari G, Galli M, Ribichini F, Rossi M, Bernardi F, Zonzin P, Piazza A, Mannucci PM, Schwartz SM, Siscovick DS, Yee J, Friedlander Y, Elosua R, Marrugat J, Lucas G, Subirana I, Sala J, Ramos R, Kathiresan S, Meigs JB, Williams G, Nathan DM, MacRae CA, O'Donnell CJ, Salomaa V, Havulinna AS, Peltonen L, Melander O, Berglund G, Voight BF, Kathiresan S, Hirschhorn JN, Asselta R, Duga S, Spreafico M, Musunuru K, Daly MJ, Purcell S, Voight BF, Purcell S, Nemesh J, Korn JM, McCarroll SA, Schwartz SM, Yee J, Kathiresan S, Lucas G, Subirana I, Elosua R, Surti A, Guiducci C, Gianniny L, Mirel D, Parkin M, Burtt N, Gabriel SB, Samani NJ, Thompson JR, Braund PS, Wright BJ, Balmforth AJ, Ball SG, Hall AS; Wellcome Trust Case Control Consortium, Schunkert H, Erdmann J, Linsel-Nitschke P, Lieb W, Ziegler A, König I, Hengstenberg C, Fischer M, Stark K, Grosshennig A, Preuss M, Wichmann HE, Schreiber S, Schunkert H, Samani NJ, Erdmann J, Ouwehand W, Hengstenberg C, Deloukas P, Scholz M, Cambien F, Reilly MP, Li M, Chen Z, Wilensky R, Matthai W, Qasim A, Hakonarson HH, Devaney J, Burnett MS, Pichard AD, Kent KM, Satler L, Lindsay JM, Waksman R, Epstein SE, Rader DJ, Scheffold T, Berger K, Stoll M, Huge A, Girelli D, Martinelli N, Olivieri O, Corrocher R, Morgan T, Spertus JA, McKeown P, Patterson CC, Schunkert H, Erdmann E, Linsel-Nitschke P, Lieb W, Ziegler A, König IR, Hengstenberg C, Fischer M, Stark K, Grosshennig A, Preuss M, Wichmann HE, Schreiber S, Hólm H, Thorleifsson G, Thorsteinsdottir U, Stefansson K, Engert JC, Do R, Xie C, Anand S, Kathiresan S, Ardissino D, Mannucci PM, Siscovick D, O'Donnell CJ, Samani NJ, Melander O, Elosua R, Peltonen L, Salomaa V, Schwartz SM, Altshuler D.

    Nat Genet. 2009 Mar;41(3):334-41. Epub 2009 Feb 8.PMID: 19198609 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Identification of susceptibility genes for complex diseases using pooling-based genome-wide association scans.

    Bossé Y, Bacot F, Montpetit A, Rung J, Qu HQ, Engert JC, Polychronakos C, Hudson TJ, Froguel P, Sladek R, Desrosiers M.

    Hum Genet. 2009 Apr;125(3):305-18. Epub 2009 Jan 29.PMID: 19184112 [PubMed - indexed for MEDLINE]Related articles

    7.

    Squalene synthase: a critical enzyme in the cholesterol biosynthesis pathway.

    Do R, Kiss RS, Gaudet D, Engert JC.

    Clin Genet. 2009 Jan;75(1):19-29. Epub 2008 Nov 27. Review.PMID: 19054015 [PubMed - indexed for MEDLINE]Related articles

    8.

    Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies.

    Keating BJ, Tischfield S, Murray SS, Bhangale T, Price TS, Glessner JT, Galver L, Barrett JC, Grant SF, Farlow DN, Chandrupatla HR, Hansen M, Ajmal S, Papanicolaou GJ, Guo Y, Li M, Derohannessian S, de Bakker PI, Bailey SD, Montpetit A, Edmondson AC, Taylor K, Gai X, Wang SS, Fornage M, Shaikh T, Groop L, Boehnke M, Hall AS, Hattersley AT, Frackelton E, Patterson N, Chiang CW, Kim CE, Fabsitz RR, Ouwehand W, Price AL, Munroe P, Caulfield M, Drake T, Boerwinkle E, Reich D, Whitehead AS, Cappola TP, Samani NJ, Lusis AJ, Schadt E, Wilson JG, Koenig W, McCarthy MI, Kathiresan S, Gabriel SB, Hakonarson H, Anand SS, Reilly M, Engert JC, Nickerson DA, Rader DJ, Hirschhorn JN, Fitzgerald GA.

    PLoS One. 2008;3(10):e3583. Epub 2008 Oct 31.PMID: 18974833 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    WW-domain-containing oxidoreductase is associated with low plasma HDL-C levels.

    Lee JC, Weissglas-Volkov D, Kyttälä M, Dastani Z, Cantor RM, Sobel EM, Plaisier CL, Engert JC, van Greevenbroek MM, Kane JP, Malloy MJ, Pullinger CR, Huertas-Vazquez A, Aguilar-Salinas CA, Tusie-Luna T, de Bruin TW, Aouizerat BE, van der Kallen CC, Croce CM, Aqeilan RI, Marcil M, Viikari JS, Lehtimäki T, Raitakari OT, Kuusisto J, Laakso M, Taskinen MR, Genest J, Pajukanta P.

    Am J Hum Genet. 2008 Aug;83(2):180-92.PMID: 18674750 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    K45R variant of squalene synthase increases total cholesterol levels in two study samples from a French Canadian population.

    Do R, Paré G, Montpetit A, Hudson TJ, Gaudet D, Engert JC.

    Hum Mutat. 2008 May;29(5):689-94.PMID: 18350552 [PubMed - indexed for MEDLINE]Related articles

    11.

    Genetic variants of FTO influence adiposity, insulin sensitivity, leptin levels, and resting metabolic rate in the Quebec Family Study.

    Do R, Bailey SD, Desbiens K, Belisle A, Montpetit A, Bouchard C, Pérusse L, Vohl MC, Engert JC.

    Diabetes. 2008 Apr;57(4):1147-50. Epub 2008 Mar 3.PMID: 18316358 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Correction of population stratification in large multi-ethnic association studies.

    Serre D, Montpetit A, Paré G, Engert JC, Yusuf S, Keavney B, Hudson TJ, Anand S.

    PLoS One. 2008 Jan 2;3(1):e1382.PMID: 18196181 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Sphingomyelin phosphodiesterase-1 (SMPD1) coding variants do not contribute to low levels of high-density lipoprotein cholesterol.

    Dastani Z, Ruel IL, Engert JC, Genest J Jr, Marcil M.

    BMC Med Genet. 2007 Dec 18;8:79.PMID: 18088425 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Identification of a chromosome 8p locus for early-onset coronary heart disease in a French Canadian population.

    Engert JC, Lemire M, Faith J, Brisson D, Fujiwara TM, Roslin NM, Brewer CG, Montpetit A, Darmond-Zwaig C, Renaud Y, Doré C, Bailey SD, Verner A, Tremblay G, St-Pierre J, Bétard C, Platko J, Rioux JD, Morgan K, Hudson TJ, Gaudet D.

    Eur J Hum Genet. 2008 Jan;16(1):105-14. Epub 2007 Sep 5.PMID: 17805225 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Familial combined hyperlipidaemia: how can genetic disorders be common, complex and comprehensible?

    Sniderman A, Bailey SD, Engert JC.

    Clin Sci (Lond). 2007 Nov;113(9):365-7.PMID: 17608621 [PubMed - indexed for MEDLINE]Related articles

    16.

    Genetic analysis of 103 candidate genes for coronary artery disease and associated phenotypes in a founder population reveals a new association between endothelin-1 and high-density lipoprotein cholesterol.

    Pare G, Serre D, Brisson D, Anand SS, Montpetit A, Tremblay G, Engert JC, Hudson TJ, Gaudet D.

    Am J Hum Genet. 2007 Apr;80(4):673-82. Epub 2007 Feb 21.PMID: 17357073 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Common polymorphisms in the promoter of the visfatin gene (PBEF1) influence plasma insulin levels in a French-Canadian population.

    Bailey SD, Loredo-Osti JC, Lepage P, Faith J, Fontaine J, Desbiens KM, Hudson TJ, Bouchard C, Gaudet D, Pérusse L, Vohl MC, Engert JC.

    Diabetes. 2006 Oct;55(10):2896-902.PMID: 17003359 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Genetics of high-density lipoproteins.

    Dastani Z, Engert JC, Genest J, Marcil M.

    Curr Opin Cardiol. 2006 Jul;21(4):329-35. Review.PMID: 16755202 [PubMed - indexed for MEDLINE]Related articles

    19.

    Identification of a novel C5L2 variant (S323I) in a French Canadian family with familial combined hyperlipemia.

    Marcil M, Vu H, Cui W, Dastani Z, Engert JC, Gaudet D, Castro-Cabezas M, Sniderman AD, Genest J Jr, Cianflone K.

    Arterioscler Thromb Vasc Biol. 2006 Jul;26(7):1619-25. Epub 2006 Apr 20.PMID: 16627811 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Evidence for a gene influencing high-density lipoprotein cholesterol on chromosome 4q31.21.

    Dastani Z, Quiogue L, Plaisier C, Engert JC, Marcil M, Genest J, Pajukanta P.

    Arterioscler Thromb Vasc Biol. 2006 Feb;26(2):392-7. Epub 2005 Dec 1.PMID: 16322534 [PubMed - indexed for MEDLINE]Related articlesFree article

    21.

    A novel nonsense apolipoprotein A-I mutation (apoA-I(E136X)) causes low HDL cholesterol in French Canadians.

    Dastani Z, Dangoisse C, Boucher B, Desbiens K, Krimbou L, Dufour R, Hegele RA, Pajukanta P, Engert JC, Genest J, Marcil M.

    Atherosclerosis. 2006 Mar;185(1):127-36. Epub 2005 Jul 14.PMID: 16023124 [PubMed - indexed for MEDLINE]Related articles

    22.

    Human resistin gene polymorphism is associated with visceral obesity and fasting and oral glucose stimulated C-peptide in the Québec Family Study.

    Bouchard L, Weisnagel SJ, Engert JC, Hudson TJ, Bouchard C, Vohl MC, Pérusse L.

    J Endocrinol Invest. 2004 Dec;27(11):1003-9.PMID: 15754730 [PubMed - indexed for MEDLINE]Related articles

    23.

    Macrophage scavenger receptor 1 999C>T (R293X) mutation and risk of prostate cancer.

    Hope Q, Bullock S, Evans C, Meitz J, Hamel N, Edwards SM, Severi G, Dearnaley D, Jhavar S, Southgate C, Falconer A, Dowe A, Muir K, Houlston RS, Engert JC, Roquis D, Sinnett D, Simard J, Heimdal K, Møller P, Maehle L, Badzioch M, Eeles RA, Easton DF, English DR, Southey MC, Hopper JL, Foulkes WD, Giles GG; Cancer Research UK/British Association of Urological Surgeons' Section of Oncology Collaborators.

    Cancer Epidemiol Biomarkers Prev. 2005 Feb;14(2):397-402.PMID: 15734964 [PubMed - indexed for MEDLINE]Related articlesFree article

    24.

    Effect of apoC-III gene polymorphisms on the lipoprotein-lipid profile of viscerally obese men.

    Couillard C, Vohl MC, Engert JC, Lemieux I, Houde A, Almeras N, Prud'homme D, Nadeau A, Despres JP, Bergeron J.

    J Lipid Res. 2003 May;44(5):986-93. Epub 2003 Feb 16.PMID: 12588953 [PubMed - indexed for MEDLINE]Related articlesFree article

    25.

    5' flanking variants of resistin are associated with obesity.

    Engert JC, Vohl MC, Williams SM, Lepage P, Loredo-Osti JC, Faith J, Doré C, Renaud Y, Burtt NP, Villeneuve A, Hirschhorn JN, Altshuler D, Groop LC, Després JP, Gaudet D, Hudson TJ.

    Diabetes. 2002 May;51(5):1629-34.PMID: 11978666 [PubMed - indexed for MEDLINE]Related articlesFree article

    26.

    ABCA1 regulatory variants influence coronary artery disease independent of effects on plasma lipid levels.

    Zwarts KY, Clee SM, Zwinderman AH, Engert JC, Singaraja R, Loubser O, James E, Roomp K, Hudson TJ, Jukema JW, Kastelein JJ, Hayden MR.

    Clin Genet. 2002 Feb;61(2):115-25.PMID: 11940086 [PubMed - indexed for MEDLINE]Related articles

    27.

    Rapid detection of the sacsin mutations causing autosomal recessive spastic ataxia of Charlevoix-Saguenay.

    Mercier J, Prévost C, Engert JC, Bouchard JP, Mathieu J, Richter A.

    Genet Test. 2001 Fall;5(3):255-9.PMID: 11788093 [PubMed - indexed for MEDLINE]Related articles

    28.

    Common genetic variation in ABCA1 is associated with altered lipoprotein levels and a modified risk for coronary artery disease.

    Clee SM, Zwinderman AH, Engert JC, Zwarts KY, Molhuizen HO, Roomp K, Jukema JW, van Wijland M, van Dam M, Hudson TJ, Brooks-Wilson A, Genest J Jr, Kastelein JJ, Hayden MR.

    Circulation. 2001 Mar 6;103(9):1198-205.PMID: 11238261 [PubMed - indexed for MEDLINE]Related articlesFree article

    29.

    Unlimited hypothesis research.

    Engert JC.

    Genome Res. 2000 Mar;10(3):271-2. No abstract available. PMID: 10720567 [PubMed - indexed for MEDLINE]Related articlesFree article

    30.

    ARSACS, a spastic ataxia common in northeastern Québec, is caused by mutations in a new gene encoding an 11.5-kb ORF.

    Engert JC, Bérubé P, Mercier J, Doré C, Lepage P, Ge B, Bouchard JP, Mathieu J, Melançon SB, Schalling M, Lander ES, Morgan K, Hudson TJ, Richter A.

    Nat Genet. 2000 Feb;24(2):120-5.PMID: 10655055 [PubMed - indexed for MEDLINE]Related articles

    31.

    Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS): high-resolution physical and transcript map of the candidate region in chromosome region 13q11.

    Engert JC, Doré C, Mercier J, Ge B, Bétard C, Rioux JD, Owen C, Bérubé P, Devon K, Birren B, Melançon SB, Morgan K, Hudson TJ, Richter A.

    Genomics. 1999 Dec 1;62(2):156-64.PMID: 10610707 [PubMed - indexed for MEDLINE]Related articles

    32.

    Proliferation precedes differentiation in IGF-I-stimulated myogenesis.

    Engert JC, Berglund EB, Rosenthal N.

    J Cell Biol. 1996 Oct;135(2):431-40.PMID: 8896599 [PubMed - indexed for MEDLINE]Related articlesFree article

    33.

    Activation of a muscle-specific enhancer by the Ski proto-oncogene.

    Engert JC, Servaes S, Sutrave P, Hughes SH, Rosenthal N.

    Nucleic Acids Res. 1995 Aug 11;23(15):2988-94.PMID: 7659522 [PubMed - indexed for MEDLINE]Related articlesFree article

    34.

    Paired MyoD-binding sites regulate myosin light chain gene expression.

    Wentworth BM, Donoghue M, Engert JC, Berglund EB, Rosenthal N.

    Proc Natl Acad Sci U S A. 1991 Feb 15;88(4):1242-6.PMID: 1847512 [PubMed - indexed for MEDLINE]Related articlesFree article

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