PubMed

Hexosamine biosynthesis pathway flux contributes to insulin resistance via altering membrane phosphatidylinositol 4,5-bisphosphate and cortical filamentous actin.

Bhonagiri P, Pattar GR, Horvath EM, Habegger KM, McCarthy AM, Elmendorf JS.

Endocrinology. 2009 Apr;150(4):1636-45. Epub 2008 Nov 26.PMID: 19036880 [PubMed - indexed for MEDLINE]Related articles

A novel membrane-based anti-diabetic action of atorvastatin.

Horvath EM, Tackett L, Elmendorf JS.

Biochem Biophys Res Commun. 2008 Aug 8;372(4):639-43. Epub 2008 Jun 2.PMID: 18514061 [PubMed - indexed for MEDLINE]Related articlesFree article

"Actin"g on GLUT4: membrane & cytoskeletal components of insulin action.

Brozinick JT Jr, Berkemeier BA, Elmendorf JS.

Curr Diabetes Rev. 2007 May;3(2):111-22. Review.PMID: 18220662 [PubMed - indexed for MEDLINE]Related articlesFree article

Interactions of endothelin and insulin: expanding parameters of insulin resistance.

Strawbridge AB, Elmendorf JS, Mather KJ.

Curr Diabetes Rev. 2006 Aug;2(3):317-27. Review.PMID: 18220636 [PubMed - indexed for MEDLINE]Related articles

Antidiabetogenic effects of chromium mitigate hyperinsulinemia-induced cellular insulin resistance via correction of plasma membrane cholesterol imbalance.

Horvath EM, Tackett L, McCarthy AM, Raman P, Brozinick JT, Elmendorf JS.

Mol Endocrinol. 2008 Apr;22(4):937-50. Epub 2007 Dec 28.PMID: 18165437 [PubMed - indexed for MEDLINE]Related articlesFree article

GLUT4's itinerary in health & disease.

McCarthy AM, Elmendorf JS.

Indian J Med Res. 2007 Mar;125(3):373-88. Review.PMID: 17496362 [PubMed - indexed for MEDLINE]Related articlesFree article

Chromium picolinate positively influences the glucose transporter system via affecting cholesterol homeostasis in adipocytes cultured under hyperglycemic diabetic conditions.

Pattar GR, Tackett L, Liu P, Elmendorf JS.

Mutat Res. 2006 Nov 7;610(1-2):93-100. Epub 2006 Jul 25.PMID: 16870493 [PubMed - indexed for MEDLINE]Related articlesFree article

Loss of cortical actin filaments in insulin-resistant skeletal muscle cells impairs GLUT4 vesicle trafficking and glucose transport.

McCarthy AM, Spisak KO, Brozinick JT, Elmendorf JS.

Am J Physiol Cell Physiol. 2006 Nov;291(5):C860-8. Epub 2006 Jun 14.PMID: 16774991 [PubMed - indexed for MEDLINE]Related articlesFree article

Chromium activates glucose transporter 4 trafficking and enhances insulin-stimulated glucose transport in 3T3-L1 adipocytes via a cholesterol-dependent mechanism.

Chen G, Liu P, Pattar GR, Tackett L, Bhonagiri P, Strawbridge AB, Elmendorf JS.

Mol Endocrinol. 2006 Apr;20(4):857-70. Epub 2005 Dec 8.PMID: 16339278 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelin-1 impairs glucose transporter trafficking via a membrane-based mechanism.

Strawbridge AB, Elmendorf JS.

J Cell Biochem. 2006 Mar 1;97(4):849-56.PMID: 16240321 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphatidylinositol 4,5-bisphosphate reverses endothelin-1-induced insulin resistance via an actin-dependent mechanism.

Strawbridge AB, Elmendorf JS.

Diabetes. 2005 Jun;54(6):1698-705.PMID: 15919791 [PubMed - indexed for MEDLINE]Related articlesFree article

Protective effect of phosphatidylinositol 4,5-bisphosphate against cortical filamentous actin loss and insulin resistance induced by sustained exposure of 3T3-L1 adipocytes to insulin.

Chen G, Raman P, Bhonagiri P, Strawbridge AB, Pattar GR, Elmendorf JS.

J Biol Chem. 2004 Sep 17;279(38):39705-9. Epub 2004 Jul 23.PMID: 15277534 [PubMed - indexed for MEDLINE]Related articlesFree article

Disruption of cortical actin in skeletal muscle demonstrates an essential role of the cytoskeleton in glucose transporter 4 translocation in insulin-sensitive tissues.

Brozinick JT Jr, Hawkins ED, Strawbridge AB, Elmendorf JS.

J Biol Chem. 2004 Sep 24;279(39):40699-706. Epub 2004 Jul 6.PMID: 15247264 [PubMed - indexed for MEDLINE]Related articlesFree article

Fluidity of insulin action.

Elmendorf JS.

Mol Biotechnol. 2004 Jun;27(2):127-38. Review.PMID: 15208455 [PubMed - indexed for MEDLINE]Related articles

Sphingomyelinase activates GLUT4 translocation via a cholesterol-dependent mechanism.

Liu P, Leffler BJ, Weeks LK, Chen G, Bouchard CM, Strawbridge AB, Elmendorf JS.

Am J Physiol Cell Physiol. 2004 Feb;286(2):C317-29. Epub 2003 Oct 1.PMID: 14522816 [PubMed - indexed for MEDLINE]Related articlesFree article

Fractionation analysis of the subcellular distribution of GLUT-4 in 3T3-L1 adipocytes.

Elmendorf JS.

Methods Mol Med. 2003;83:105-11. No abstract available. PMID: 12619721 [PubMed - indexed for MEDLINE]Related articles

Analysis of insulin-stimulated glucose uptake in differentiated 3T3-L1 adipocytes.

Lakshmanan J, Elmendorf JS, Ozcan S.

Methods Mol Med. 2003;83:97-103. No abstract available. PMID: 12619720 [PubMed - indexed for MEDLINE]Related articles

Signals that regulate GLUT4 translocation.

Elmendorf JS.

J Membr Biol. 2002 Dec 1;190(3):167-74. Review. No abstract available. PMID: 12533782 [PubMed - indexed for MEDLINE]Related articles

Glucosamine-induced insulin resistance is coupled to O-linked glycosylation of Munc18c.

Chen G, Liu P, Thurmond DC, Elmendorf JS.

FEBS Lett. 2003 Jan 16;534(1-3):54-60.PMID: 12527361 [PubMed - indexed for MEDLINE]Related articles

Osteoblast intracellular localization of Nmp4 proteins.

Torrungruang K, Shah R, Alvarez M, Bowen DK, Gerard R, Pavalko FM, Elmendorf JS, Charoonpatrapong K, Hock J, Rhodes SJ, Bidwell JP.

Bone. 2002 Jun;30(6):931-6.PMID: 12052465 [PubMed - indexed for MEDLINE]Related articles

Ceramide and glucosamine antagonism of alternate signaling pathways regulating insulin- and osmotic shock-induced glucose transporter 4 translocation.

Kralik SF, Liu P, Leffler BJ, Elmendorf JS.

Endocrinology. 2002 Jan;143(1):37-46.PMID: 11751589 [PubMed - indexed for MEDLINE]Related articlesFree article

Calmodulin antagonists inhibit insulin-stimulated GLUT4 (glucose transporter 4) translocation by preventing the formation of phosphatidylinositol 3,4,5-trisphosphate in 3T3L1 adipocytes.

Yang C, Watson RT, Elmendorf JS, Sacks DB, Pessin JE.

Mol Endocrinol. 2000 Feb;14(2):317-26.PMID: 10674403 [PubMed - indexed for MEDLINE]Related articlesFree article

Temporal separation of insulin-stimulated GLUT4/IRAP vesicle plasma membrane docking and fusion in 3T3L1 adipocytes.

Elmendorf JS, Boeglin DJ, Pessin JE.

J Biol Chem. 1999 Dec 24;274(52):37357-61.PMID: 10601305 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin signaling regulating the trafficking and plasma membrane fusion of GLUT4-containing intracellular vesicles.

Elmendorf JS, Pessin JE.

Exp Cell Res. 1999 Nov 25;253(1):55-62. Review. No abstract available. PMID: 10579911 [PubMed - indexed for MEDLINE]Related articles

Synip: a novel insulin-regulated syntaxin 4-binding protein mediating GLUT4 translocation in adipocytes.

Min J, Okada S, Kanzaki M, Elmendorf JS, Coker KJ, Ceresa BP, Syu LJ, Noda Y, Saltiel AR, Pessin JE.

Mol Cell. 1999 Jun;3(6):751-60. Erratum in: Mol Cell 1999 Jul;4(1):following 192. PMID: 10394363 [PubMed - indexed for MEDLINE]Related articles

Molecular basis of insulin-stimulated GLUT4 vesicle trafficking. Location! Location! Location!

Pessin JE, Thurmond DC, Elmendorf JS, Coker KJ, Okada S.

J Biol Chem. 1999 Jan 29;274(5):2593-6. Review. No abstract available. PMID: 9915783 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of insulin-stimulated GLUT4 translocation by Munc18c in 3T3L1 adipocytes.

Thurmond DC, Ceresa BP, Okada S, Elmendorf JS, Coker K, Pessin JE.

J Biol Chem. 1998 Dec 11;273(50):33876-83.PMID: 9837979 [PubMed - indexed for MEDLINE]Related articlesFree article

Guanosine 5'-O-(3-thiotriphosphate) (GTPgammaS) stimulation of GLUT4 translocation is tyrosine kinase-dependent.

Elmendorf JS, Chen D, Pessin JE.

J Biol Chem. 1998 May 22;273(21):13289-96.PMID: 9582374 [PubMed - indexed for MEDLINE]Related articlesFree article

Osmotic shock stimulates GLUT4 translocation in 3T3L1 adipocytes by a novel tyrosine kinase pathway.

Chen D, Elmendorf JS, Olson AL, Li X, Earp HS, Pessin JE.

J Biol Chem. 1997 Oct 24;272(43):27401-10.PMID: 9341192 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of monensin on 2-deoxyglucose uptake, the insulin receptor and phosphatidylinositol 3-kinase activity in rat muscle.

Turinsky J, Damrau-Abney A, Elmendorf JS, Smith TR.

J Endocrinol. 1997 Jul;154(1):85-93.PMID: 9246941 [PubMed - indexed for MEDLINE]Related articles

Growth hormone-induced insulin resistance: role of the insulin receptor, IRS-1, GLUT-1, and GLUT-4.

Smith TR, Elmendorf JS, David TS, Turinsky J.

Am J Physiol. 1997 Jun;272(6 Pt 1):E1071-9.PMID: 9227454 [PubMed - indexed for MEDLINE]Related articles

Phosphatidylinositol 3-kinase and dynamics of insulin resistance in denervated slow and fast muscles in vivo.

Elmendorf JS, Damrau-Abney A, Smith TR, David TS, Turinsky J.

Am J Physiol. 1997 Apr;272(4 Pt 1):E661-70.PMID: 9142889 [PubMed - indexed for MEDLINE]Related articles

Sphingomyelinase stimulates 2-deoxyglucose uptake by skeletal muscle.

Turinsky J, Nagel GW, Elmendorf JS, Damrau-Abney A, Smith TR.

Biochem J. 1996 Jan 1;313 ( Pt 1):215-22.PMID: 8546686 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-stimulated phosphatidylinositol 3-kinase activity and 2-deoxy-D-glucose uptake in rat skeletal muscles.

Elmendorf JS, Damrau-Abney A, Smith TR, David TS, Turinsky J.

Biochem Biophys Res Commun. 1995 Mar 28;208(3):1147-53.PMID: 7702613 [PubMed - indexed for MEDLINE]Related articles