PubMed

Interleukin-10 prevents diet-induced insulin resistance by attenuating macrophage and cytokine response in skeletal muscle.

Hong EG, Ko HJ, Cho YR, Kim HJ, Ma Z, Yu TY, Friedline RH, Kurt-Jones E, Finberg R, Fischer MA, Granger EL, Norbury CC, Hauschka SD, Philbrick WM, Lee CG, Elias JA, Kim JK.

Diabetes. 2009 Nov;58(11):2525-35. Epub 2009 Aug 18.PMID: 19690064 [PubMed - in process]Related articles

Lung vascular endothelial growth factor expression induces local myeloid dendritic cell activation.

Chapoval SP, Lee CG, Tang C, Keegan AD, Cohn L, Bottomly K, Elias JA.

Clin Immunol. 2009 Sep;132(3):371-84. Epub 2009 Jun 24.PMID: 19553159 [PubMed - indexed for MEDLINE]Related articles

Novel biomarkers in asthma: chemokines and chitinase-like proteins.

Hartl D, Lee CG, Da Silva CA, Chupp GL, Elias JA.

Curr Opin Allergy Clin Immunol. 2009 Feb;9(1):60-6. Review.PMID: 19532094 [PubMed - indexed for MEDLINE]Related articles

Primary Neisseria meningitidis Keratitis.

Elias JA, Pandit RT.

Cornea. 2009 Jul;28(6):714-5. No abstract available. PMID: 19512893 [PubMed - indexed for MEDLINE]Related articles

Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis.

Lee CG, Hartl D, Lee GR, Koller B, Matsuura H, Da Silva CA, Sohn MH, Cohn L, Homer RJ, Kozhich AA, Humbles A, Kearley J, Coyle A, Chupp G, Reed J, Flavell RA, Elias JA.

J Exp Med. 2009 May 11;206(5):1149-66. Epub 2009 May 4.PMID: 19414556 [PubMed - indexed for MEDLINE]Related articlesFree article

Acidic mammalian chitinase regulates epithelial cell apoptosis via a chitinolytic-independent mechanism.

Hartl D, He CH, Koller B, Da Silva CA, Kobayashi Y, Lee CG, Flavell RA, Elias JA.

J Immunol. 2009 Apr 15;182(8):5098-106.PMID: 19342690 [PubMed - indexed for MEDLINE]Related articles

Chitin is a size-dependent regulator of macrophage TNF and IL-10 production.

Da Silva CA, Chalouni C, Williams A, Hartl D, Lee CG, Elias JA.

J Immunol. 2009 Mar 15;182(6):3573-82.PMID: 19265136 [PubMed - indexed for MEDLINE]Related articles

Genetic variation in the promoter region of chitinase 3-like 1 is associated with atopy.

Sohn MH, Lee JH, Kim KW, Kim SW, Lee SH, Kim KE, Kim KH, Lee CG, Elias JA, Lee MG.

Am J Respir Crit Care Med. 2009 Mar 15;179(6):449-56. Epub 2008 Dec 23.PMID: 19106306 [PubMed - indexed for MEDLINE]Related articles

[Effects of ramipril and simvastatin on the oxidative stress of diabetic rats]

Elias JA, Delfino VD, Barbosa DS, Fabris BA, Matsuo T.

Arq Bras Endocrinol Metabol. 2008 Oct;52(7):1131-8. Portuguese. PMID: 19082301 [PubMed - in process]Related articlesFree article

Chitin regulation of immune responses: an old molecule with new roles.

Lee CG, Da Silva CA, Lee JY, Hartl D, Elias JA.

Curr Opin Immunol. 2008 Dec;20(6):684-9. Epub 2008 Nov 1.PMID: 18938241 [PubMed - indexed for MEDLINE]Related articles

Acidic mammalian chitinase is secreted via an ADAM17/epidermal growth factor receptor-dependent pathway and stimulates chemokine production by pulmonary epithelial cells.

Hartl D, He CH, Koller B, Da Silva CA, Homer R, Lee CG, Elias JA.

J Biol Chem. 2008 Nov 28;283(48):33472-82. Epub 2008 Sep 29.PMID: 18824549 [PubMed - indexed for MEDLINE]Related articles

Elevated serum angiopoietin 2 levels are associated with increased mortality in sepsis.

Siner JM, Bhandari V, Engle KM, Elias JA, Siegel MD.

Shock. 2009 Apr;31(4):348-53.PMID: 18791490 [PubMed - indexed for MEDLINE]Related articles

TLR-2 and IL-17A in chitin-induced macrophage activation and acute inflammation.

Da Silva CA, Hartl D, Liu W, Lee CG, Elias JA.

J Immunol. 2008 Sep 15;181(6):4279-86.PMID: 18768886 [PubMed - indexed for MEDLINE]Related articlesFree article

Cigarette smoke selectively enhances viral PAMP- and virus-induced pulmonary innate immune and remodeling responses in mice.

Kang MJ, Lee CG, Lee JY, Dela Cruz CS, Chen ZJ, Enelow R, Elias JA.

J Clin Invest. 2008 Aug;118(8):2771-84.PMID: 18654661 [PubMed - indexed for MEDLINE]Related articlesFree article

Endogenous IL-11 signaling is essential in Th2- and IL-13-induced inflammation and mucus production.

Lee CG, Hartl D, Matsuura H, Dunlop FM, Scotney PD, Fabri LJ, Nash AD, Chen NY, Tang CY, Chen Q, Homer RJ, Baca M, Elias JA.

Am J Respir Cell Mol Biol. 2008 Dec;39(6):739-46. Epub 2008 Jul 10.PMID: 18617680 [PubMed - indexed for MEDLINE]Related articles

Developmental regulation of NO-mediated VEGF-induced effects in the lung.

Bhandari V, Choo-Wing R, Lee CG, Yusuf K, Nedrelow JH, Ambalavanan N, Malkus H, Homer RJ, Elias JA.

Am J Respir Cell Mol Biol. 2008 Oct;39(4):420-30. Epub 2008 Apr 25.PMID: 18441284 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of transforming growth factor beta1-driven genetic programs of acute lung fibrosis.

Pulichino AM, Wang IM, Caron A, Mortimer J, Auger A, Boie Y, Elias JA, Kartono A, Xu L, Menetski J, Sayegh CE.

Am J Respir Cell Mol Biol. 2008 Sep;39(3):324-36. Epub 2008 Apr 10.PMID: 18403781 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function.

Ober C, Tan Z, Sun Y, Possick JD, Pan L, Nicolae R, Radford S, Parry RR, Heinzmann A, Deichmann KA, Lester LA, Gern JE, Lemanske RF Jr, Nicolae DL, Elias JA, Chupp GL.

N Engl J Med. 2008 Apr 17;358(16):1682-91. Epub 2008 Apr 9.PMID: 18403759 [PubMed - indexed for MEDLINE]Related articlesFree article

IL-13 receptor alpha2 selectively inhibits IL-13-induced responses in the murine lung.

Zheng T, Liu W, Oh SY, Zhu Z, Hu B, Homer RJ, Cohn L, Grusby MJ, Elias JA.

J Immunol. 2008 Jan 1;180(1):522-9.PMID: 18097054 [PubMed - indexed for MEDLINE]Related articlesFree article

A chitinase-like protein in the lung and circulation of patients with severe asthma.

Chupp GL, Lee CG, Jarjour N, Shim YM, Holm CT, He S, Dziura JD, Reed J, Coyle AJ, Kiener P, Cullen M, Grandsaigne M, Dombret MC, Aubier M, Pretolani M, Elias JA.

N Engl J Med. 2007 Nov 15;357(20):2016-27.PMID: 18003958 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of NF-kappaB activation reduces the tissue effects of transgenic IL-13.

Chapoval SP, Al-Garawi A, Lora JM, Strickland I, Ma B, Lee PJ, Homer RJ, Ghosh S, Coyle AJ, Elias JA.

J Immunol. 2007 Nov 15;179(10):7030-41.PMID: 17982094 [PubMed - indexed for MEDLINE]Related articlesFree article

P21 regulates TGF-beta1-induced pulmonary responses via a TNF-alpha-signaling pathway.

Yamasaki M, Kang HR, Homer RJ, Chapoval SP, Cho SJ, Lee BJ, Elias JA, Lee CG.

Am J Respir Cell Mol Biol. 2008 Mar;38(3):346-53. Epub 2007 Oct 11.PMID: 17932374 [PubMed - indexed for MEDLINE]Related articlesFree article

Semaphorin 7A plays a critical role in TGF-beta1-induced pulmonary fibrosis.

Kang HR, Lee CG, Homer RJ, Elias JA.

J Exp Med. 2007 May 14;204(5):1083-93. Epub 2007 May 7.PMID: 17485510 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of angiopoietin 2 in hyperoxia-induced acute lung injury.

Bhandari V, Elias JA.

Cell Cycle. 2007 May 2;6(9):1049-52. Epub 2007 May 2. Review.PMID: 17438375 [PubMed - indexed for MEDLINE]Related articles

Increased hyperoxia-induced mortality and acute lung injury in IL-13 null mice.

Bhandari V, Choo-Wing R, Homer RJ, Elias JA.

J Immunol. 2007 Apr 15;178(8):4993-5000.PMID: 17404281 [PubMed - indexed for MEDLINE]Related articlesFree article

Developmental differences in the responses of IL-6 and IL-13 transgenic mice exposed to hyperoxia.

Choo-Wing R, Nedrelow JH, Homer RJ, Elias JA, Bhandari V.

Am J Physiol Lung Cell Mol Physiol. 2007 Jul;293(1):L142-50. Epub 2007 Mar 30.PMID: 17400600 [PubMed - indexed for MEDLINE]Related articlesFree article

Recombinant basic fibroblast growth factor inhibits the airway hyperresponsiveness, mucus production, and lung inflammation induced by an allergen challenge.

Jeon SG, Lee CG, Oh MH, Chun EY, Gho YS, Cho SH, Kim JH, Min KU, Kim YY, Kim YK, Elias JA.

J Allergy Clin Immunol. 2007 Apr;119(4):831-7. Epub 2007 Feb 7.PMID: 17289133 [PubMed - indexed for MEDLINE]Related articles

VEGF-induced heme oxygenase-1 confers cytoprotection from lethal hyperoxia in vivo.

Siner JM, Jiang G, Cohen ZI, Shan P, Zhang X, Lee CG, Elias JA, Lee PJ.

FASEB J. 2007 May;21(7):1422-32. Epub 2007 Jan 30.PMID: 17264168 [PubMed - indexed for MEDLINE]Related articlesFree article

IL-18 is induced and IL-18 receptor alpha plays a critical role in the pathogenesis of cigarette smoke-induced pulmonary emphysema and inflammation.

Kang MJ, Homer RJ, Gallo A, Lee CG, Crothers KA, Cho SJ, Rochester C, Cain H, Chupp G, Yoon HJ, Elias JA.

J Immunol. 2007 Feb 1;178(3):1948-59.PMID: 17237446 [PubMed - indexed for MEDLINE]Related articlesFree article

Transforming growth factor (TGF)-beta1 stimulates pulmonary fibrosis and inflammation via a Bax-dependent, bid-activated pathway that involves matrix metalloproteinase-12.

Kang HR, Cho SJ, Lee CG, Homer RJ, Elias JA.

J Biol Chem. 2007 Mar 9;282(10):7723-32. Epub 2007 Jan 5.PMID: 17209037 [PubMed - indexed for MEDLINE]Related articlesFree article

IL-13 is associated with reduced illness and replication in primary respiratory syncytial virus infection in the mouse.

Zhou W, Hashimoto K, Moore ML, Elias JA, Zhu Z, Durbin J, Colasurdo G, Rutigliano JA, Chiappetta CL, Goleniewska K, O'Neal JF, Graham BS, Peebles RS Jr.

Microbes Infect. 2006 Nov-Dec;8(14-15):2880-9. Epub 2006 Oct 24.PMID: 17110149 [PubMed - indexed for MEDLINE]Related articlesFree article

Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death.

Bhandari V, Choo-Wing R, Lee CG, Zhu Z, Nedrelow JH, Chupp GL, Zhang X, Matthay MA, Ware LB, Homer RJ, Lee PJ, Geick A, de Fougerolles AR, Elias JA.

Nat Med. 2006 Nov;12(11):1286-93. Epub 2006 Nov 5.PMID: 17086189 [PubMed - indexed for MEDLINE]Related articlesFree article

Opposing actions of Stat1 and Stat6 on IL-13-induced up-regulation of early growth response-1 and platelet-derived growth factor ligands in pulmonary fibroblasts.

Ingram JL, Antao-Menezes A, Mangum JB, Lyght O, Lee PJ, Elias JA, Bonner JC.

J Immunol. 2006 Sep 15;177(6):4141-8.PMID: 16951379 [PubMed - indexed for MEDLINE]Related articlesFree article

IFN-gamma-dependent DNA injury and/or apoptosis are critical in cigarette smoke-induced murine emphysema.

Kang MJ, Lee CG, Cho SJ, Homer RJ, Elias JA.

Proc Am Thorac Soc. 2006 Aug;3(6):517-8. No abstract available. PMID: 16921135 [PubMed - indexed for MEDLINE]Related articlesFree article

State of the art. Mechanistic heterogeneity in chronic obstructive pulmonary disease: insights from transgenic mice.

Elias JA, Kang MJ, Crothers K, Homer R, Lee CG.

Proc Am Thorac Soc. 2006 Aug;3(6):494-8. Review. Erratum in: Proc Am Thorac Soc. 2007 Aug 15;4(5):473. Crouthers, Kristina [corrected to Crothers, Kristina]. PMID: 16921126 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic control of transforming growth factor-beta1-induced emphysema and fibrosis in the murine lung.

Lee CG, Cho S, Homer RJ, Elias JA.

Proc Am Thorac Soc. 2006 Aug;3(6):476-477. No abstract available. PMID: 16921114 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of 5-lipoxygenase in IL-13-induced pulmonary inflammation and remodeling.

Shim YM, Zhu Z, Zheng T, Lee CG, Homer RJ, Ma B, Elias JA.

J Immunol. 2006 Aug 1;177(3):1918-24.PMID: 16849505 [PubMed - indexed for MEDLINE]Related articlesFree article

Essential role of nitric oxide in VEGF-induced, asthma-like angiogenic, inflammatory, mucus, and physiologic responses in the lung.

Bhandari V, Choo-Wing R, Chapoval SP, Lee CG, Tang C, Kim YK, Ma B, Baluk P, Lin MI, McDonald DM, Homer RJ, Sessa WC, Elias JA.

Proc Natl Acad Sci U S A. 2006 Jul 18;103(29):11021-6. Epub 2006 Jul 10.PMID: 16832062 [PubMed - indexed for MEDLINE]Related articlesFree article

Transgenic modeling of transforming growth factor-beta(1): role of apoptosis in fibrosis and alveolar remodeling.

Lee CG, Kang HR, Homer RJ, Chupp G, Elias JA.

Proc Am Thorac Soc. 2006 Jul;3(5):418-23. Review.PMID: 16799085 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytokines in tolerance to hyperoxia-induced injury in the developing and adult lung.

Bhandari V, Elias JA.

Free Radic Biol Med. 2006 Jul 1;41(1):4-18. Epub 2006 Feb 17. Review.PMID: 16781448 [PubMed - indexed for MEDLINE]Related articles

Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis.

Ma B, Blackburn MR, Lee CG, Homer RJ, Liu W, Flavell RA, Boyden L, Lifton RP, Sun CX, Young HW, Elias JA.

J Clin Invest. 2006 May;116(5):1274-83.PMID: 16670768 [PubMed - indexed for MEDLINE]Related articlesFree article

Association between genetic variations of vascular endothelial growth factor receptor 2 and atopy in the Korean population.

Park HW, Lee JE, Shin ES, Lee JY, Bahn JW, Oh HB, Oh SY, Cho SH, Moon HB, Min KU, Elias JA, Kim YY, Kim YK.

J Allergy Clin Immunol. 2006 Apr;117(4):774-9. Epub 2006 Mar 9.PMID: 16630933 [PubMed - indexed for MEDLINE]Related articles

Role of CCR5 in the pathogenesis of IL-13-induced inflammation and remodeling.

Ma B, Liu W, Homer RJ, Lee PJ, Coyle AJ, Lora JM, Lee CG, Elias JA.

J Immunol. 2006 Apr 15;176(8):4968-78.PMID: 16585593 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential expression of chitinases identify subsets of murine airway epithelial cells in allergic inflammation.

Homer RJ, Zhu Z, Cohn L, Lee CG, White WI, Chen S, Elias JA.

Am J Physiol Lung Cell Mol Physiol. 2006 Sep;291(3):L502-11. Epub 2006 Mar 23.PMID: 16556727 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of early growth response-1 (Egr-1) in interleukin-13-induced inflammation and remodeling.

Cho SJ, Kang MJ, Homer RJ, Kang HR, Zhang X, Lee PJ, Elias JA, Lee CG.

J Biol Chem. 2006 Mar 24;281(12):8161-8. Epub 2006 Jan 26.PMID: 16439363 [PubMed - indexed for MEDLINE]Related articlesFree article

ERK1/2 mitogen-activated protein kinase selectively mediates IL-13-induced lung inflammation and remodeling in vivo.

Lee PJ, Zhang X, Shan P, Ma B, Lee CG, Homer RJ, Zhu Z, Rincon M, Mossman BT, Elias JA.

J Clin Invest. 2006 Jan;116(1):163-73. Epub 2005 Dec 22.PMID: 16374521 [PubMed - indexed for MEDLINE]Related articlesFree article

Allergen-induced airway hyperresponsiveness mediated by cyclooxygenase inhibition is not dependent on 5-lipoxygenase or IL-5, but is IL-13 dependent.

Peebles RS Jr, Hashimoto K, Sheller JR, Moore ML, Morrow JD, Ji S, Elias JA, Goleniewska K, O'neal J, Mitchell DB, Graham BS, Zhou W.

J Immunol. 2005 Dec 15;175(12):8253-9.PMID: 16339565 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of CCR5 in IFN-gamma-induced and cigarette smoke-induced emphysema.

Ma B, Kang MJ, Lee CG, Chapoval S, Liu W, Chen Q, Coyle AJ, Lora JM, Picarella D, Homer RJ, Elias JA.

J Clin Invest. 2005 Dec;115(12):3460-72. Epub 2005 Nov 10.PMID: 16284650 [PubMed - indexed for MEDLINE]Related articlesFree article

Partially adenosine deaminase-deficient mice develop pulmonary fibrosis in association with adenosine elevations.

Chunn JL, Mohsenin A, Young HW, Lee CG, Elias JA, Kellems RE, Blackburn MR.

Am J Physiol Lung Cell Mol Physiol. 2006 Mar;290(3):L579-87. Epub 2005 Oct 28.PMID: 16258000 [PubMed - indexed for MEDLINE]Related articlesFree article

Chitinases and chitinase-like proteins in T(H)2 inflammation and asthma.

Elias JA, Homer RJ, Hamid Q, Lee CG.

J Allergy Clin Immunol. 2005 Sep;116(3):497-500. Review.PMID: 16159614 [PubMed - indexed for MEDLINE]Related articles