PubMed

Early Intervention of Tyrosine Nitration Prevents Vaso-obliteration and Neovascularization in Ischemic Retinopathy.

Abdelsaid MA, Pillai BA, Matragoon S, Prakash R, Al-Shabrawey M, El-Remessy AB.

J Pharmacol Exp Ther. 2009 Oct 8. [Epub ahead of print]PMID: 19815813 [PubMed - as supplied by publisher]Related articlesFree article

Adaptive Cerebral Neovascularization in a Model of Type 2 Diabetes: Relevance to Focal Cerebral Ischemia.

Li W, Prakash R, Kelly-Cobbs AI, Ogbi S, Kozak A, El-Remessy AB, Schreihofer DA, Fagan SC, Ergul A.

Diabetes. 2009 Oct 6. [Epub ahead of print]PMID: 19808897 [PubMed - as supplied by publisher]Related articles

Minocycline and tissue-type plasminogen activator for stroke: assessment of interaction potential.

Machado LS, Sazonova IY, Kozak A, Wiley DC, El-Remessy AB, Ergul A, Hess DC, Waller JL, Fagan SC.

Stroke. 2009 Sep;40(9):3028-33. Epub 2009 Jul 23.PMID: 19628804 [PubMed - indexed for MEDLINE]Related articles

Early atorvastatin reduces hemorrhage after acute cerebral ischemia in diabetic rats.

Elewa HF, Kozak A, El-Remessy AB, Frye RF, Johnson MH, Ergul A, Fagan SC.

J Pharmacol Exp Ther. 2009 Aug;330(2):532-40. Epub 2009 May 28.PMID: 19478137 [PubMed - indexed for MEDLINE]Related articles

Candesartan augments ischemia-induced proangiogenic state and results in sustained improvement after stroke.

Kozak A, Ergul A, El-Remessy AB, Johnson MH, Machado LS, Elewa HF, Abdelsaid M, Wiley DC, Fagan SC.

Stroke. 2009 May;40(5):1870-6. Epub 2009 Mar 5.PMID: 19265050 [PubMed - indexed for MEDLINE]Related articles

Diabetic retinopathy: current management and experimental therapeutic targets.

Ali TK, El-Remessy AB.

Pharmacotherapy. 2009 Feb;29(2):182-92. Review.PMID: 19170588 [PubMed - indexed for MEDLINE]Related articles

Poly(ADP-ribose)polymerase inhibition counteracts cataract formation and early retinal changes in streptozotocin-diabetic rats.

Drel VR, Xu W, Zhang J, Kador PF, Ali TK, Shin J, Julius U, Slusher B, El-Remessy AB, Obrosova IG.

Invest Ophthalmol Vis Sci. 2009 Apr;50(4):1778-90. Epub 2008 Dec 20.PMID: 19098320 [PubMed - indexed for MEDLINE]Related articles

HMG-CoA reductase inhibitors (statin) prevents retinal neovascularization in a model of oxygen-induced retinopathy.

Bartoli M, Al-Shabrawey M, Labazi M, Behzadian MA, Istanboli M, El-Remessy AB, Caldwell RW, Marcus DM, Caldwell RB.

Invest Ophthalmol Vis Sci. 2009 Oct;50(10):4934-40. Epub 2008 Dec 20.PMID: 19098312 [PubMed - indexed for MEDLINE]Related articles

Neuroprotective effects of cannabidiol in endotoxin-induced uveitis: critical role of p38 MAPK activation.

El-Remessy AB, Tang Y, Zhu G, Matragoon S, Khalifa Y, Liu EK, Liu JY, Hanson E, Mian S, Fatteh N, Liou GI.

Mol Vis. 2008;14:2190-203. Epub 2008 Dec 3.PMID: 19052649 [PubMed - indexed for MEDLINE]Related articlesFree article

Aldose reductase inhibitor fidarestat counteracts diabetes-associated cataract formation, retinal oxidative-nitrosative stress, glial activation, and apoptosis.

Drel VR, Pacher P, Ali TK, Shin J, Julius U, El-Remessy AB, Obrosova IG.

Int J Mol Med. 2008 Jun;21(6):667-76.PMID: 18506358 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of NADPH oxidase and Stat3 in statin-mediated protection against diabetic retinopathy.

Al-Shabrawey M, Bartoli M, El-Remessy AB, Ma G, Matragoon S, Lemtalsi T, Caldwell RW, Caldwell RB.

Invest Ophthalmol Vis Sci. 2008 Jul;49(7):3231-8. Epub 2008 Mar 31.PMID: 18378570 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxynitrite mediates retinal neurodegeneration by inhibiting nerve growth factor survival signaling in experimental and human diabetes.

Ali TK, Matragoon S, Pillai BA, Liou GI, El-Remessy AB.

Diabetes. 2008 Apr;57(4):889-98. Epub 2008 Feb 19.PMID: 18285558 [PubMed - indexed for MEDLINE]Related articlesFree article

Diabetes-induced coronary vascular dysfunction involves increased arginase activity.

Romero MJ, Platt DH, Tawfik HE, Labazi M, El-Remessy AB, Bartoli M, Caldwell RB, Caldwell RW.

Circ Res. 2008 Jan 4;102(1):95-102. Epub 2007 Oct 25.PMID: 17967788 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxynitrite mediates VEGF's angiogenic signal and function via a nitration-independent mechanism in endothelial cells.

El-Remessy AB, Al-Shabrawey M, Platt DH, Bartoli M, Behzadian MA, Ghaly N, Tsai N, Motamed K, Caldwell RB.

FASEB J. 2007 Aug;21(10):2528-39. Epub 2007 Mar 23.PMID: 17384142 [PubMed - indexed for MEDLINE]Related articlesFree article

Simvastatin improves diabetes-induced coronary endothelial dysfunction.

Tawfik HE, El-Remessy AB, Matragoon S, Ma G, Caldwell RB, Caldwell RW.

J Pharmacol Exp Ther. 2006 Oct;319(1):386-95. Epub 2006 Jul 18.PMID: 16849625 [PubMed - indexed for MEDLINE]Related articlesFree article

Neuroprotective and blood-retinal barrier-preserving effects of cannabidiol in experimental diabetes.

El-Remessy AB, Al-Shabrawey M, Khalifa Y, Tsai NT, Caldwell RB, Liou GI.

Am J Pathol. 2006 Jan;168(1):235-44.PMID: 16400026 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxynitrite increases VEGF expression in vascular endothelial cells via STAT3.

Platt DH, Bartoli M, El-Remessy AB, Al-Shabrawey M, Lemtalsi T, Fulton D, Caldwell RB.

Free Radic Biol Med. 2005 Nov 15;39(10):1353-61.PMID: 16257644 [PubMed - indexed for MEDLINE]Related articles

Inhibition of NAD(P)H oxidase activity blocks vascular endothelial growth factor overexpression and neovascularization during ischemic retinopathy.

Al-Shabrawey M, Bartoli M, El-Remessy AB, Platt DH, Matragoon S, Behzadian MA, Caldwell RW, Caldwell RB.

Am J Pathol. 2005 Aug;167(2):599-607.PMID: 16049343 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidative stress inactivates VEGF survival signaling in retinal endothelial cells via PI 3-kinase tyrosine nitration.

el-Remessy AB, Bartoli M, Platt DH, Fulton D, Caldwell RB.

J Cell Sci. 2005 Jan 1;118(Pt 1):243-52.PMID: 15615788 [PubMed - indexed for MEDLINE]Related articlesFree article

Neuroprotective effect of (-)Delta9-tetrahydrocannabinol and cannabidiol in N-methyl-D-aspartate-induced retinal neurotoxicity: involvement of peroxynitrite.

El-Remessy AB, Khalil IE, Matragoon S, Abou-Mohamed G, Tsai NJ, Roon P, Caldwell RB, Caldwell RW, Green K, Liou GI.

Am J Pathol. 2003 Nov;163(5):1997-2008.PMID: 14578199 [PubMed - indexed for MEDLINE]Related articlesFree article

Roles of superoxide, peroxynitrite, and protein kinase C in the development of tolerance to nitroglycerin.

Abou-Mohamed G, Johnson JA, Jin L, El-Remessy AB, Do K, Kaesemeyer WH, Caldwell RB, Caldwell RW.

J Pharmacol Exp Ther. 2004 Jan;308(1):289-99. Epub 2003 Oct 16.PMID: 14563789 [PubMed - indexed for MEDLINE]Related articlesFree article

High glucose-induced tyrosine nitration in endothelial cells: role of eNOS uncoupling and aldose reductase activation.

El-Remessy AB, Abou-Mohamed G, Caldwell RW, Caldwell RB.

Invest Ophthalmol Vis Sci. 2003 Jul;44(7):3135-43.PMID: 12824263 [PubMed - indexed for MEDLINE]Related articlesFree article

Experimental diabetes causes breakdown of the blood-retina barrier by a mechanism involving tyrosine nitration and increases in expression of vascular endothelial growth factor and urokinase plasminogen activator receptor.

El-Remessy AB, Behzadian MA, Abou-Mohamed G, Franklin T, Caldwell RW, Caldwell RB.

Am J Pathol. 2003 Jun;162(6):1995-2004.PMID: 12759255 [PubMed - indexed for MEDLINE]Related articlesFree article

Hyperoxia induces retinal vascular endothelial cell apoptosis through formation of peroxynitrite.

Gu X, El-Remessy AB, Brooks SE, Al-Shabrawey M, Tsai NT, Caldwell RB.

Am J Physiol Cell Physiol. 2003 Sep;285(3):C546-54. Epub 2003 May 7.PMID: 12736139 [PubMed - indexed for MEDLINE]Related articlesFree article